Heavy Traffic Can Be Heartbreaking
...igher for those living 100 meters to 200 meters (328 to 642 feet) away. hoffmann compares the damage wrought by traffic fumes to the effects of aging. "Livi...k, lowering cholesterol, increasing physical activity and quitting smoking, hoffmann said. Reducing air pollution is a larger challenge. In big U.S. cit...David W. Keiser to Retire as President of Alexion
...established in 1992, bringing to the start-up organization nearly 15 years of international experience with leading pharmaceutical companies including hoffmann La Roche and G.D. Searle. At Alexion, he played a central role in managing the Company's manufacturing and regulatory efforts, and then initiated the ...Defining the Value of Medicine in an Evidence-Based Healthcare Marketplace
...alue of medicine during the Summit are: -- Personalized Medicine: How Industry and Government Can Make it Happen George Abercrombie - CEO, hoffmann La-Roche, Inc. -- Keynote Address Tevi D. Troy - Deputy Secretary, HHS -- Paying for Innovation: CMS' Approach to Coverage Steve Phurrough -...Implications of Statin Therapy in Bladder Cancer Patients
...es due to a perceived significant impact on overall mortality from cardiac disease. In the January issue of the New England Journal of Medicine, hoffmann and colleagues reported on a series of patients with bladder cancer who were treated with BCG. Of the 84 patients, 19 were also receiving statin thera...Schering-Plough Expands Vicriviroc Phase II Study in Treatment-Naive Patients With HIV
...mmission filings, including Part II, Item 1A. "Risk Factors" in the Company's first quarter 2009 10-Q, filed May 1, 2009. Endnotes 1 hoffmann C (2007) The epidemiology of HIV coreceptor tropism. Eur J Med Res (2007) 12: 385-390. 2 Atazanavir sulfate is a Bristol-Myers Squibb Company pre...Schering-Plough Initiates Phase II Study With Vicriviroc in Treatment-Naive HIV-Infected Patients
...g- Plough's Securities and Exchange Commission filings, including Part I, Item 1A. "Risk Factors" in Schering-Plough's 2007 10-K/A. References 1 hoffmann C (2007) The epidemiology of HIV coreceptor tropism. Eur J Med Res (2007) 12: 385-390. 2 Atazanavir sulfate is a Bristol-Myers Squibb Company pres...AngioGenex Files Patent on First Small Molecule Id-Inhibitors for the Treatment of Cancer
...al to develop orally active anti-cancer drugs," said Dr. Richard Salvador, President and CEO, and the former global head of Preclinical Development at hoffmann La Roche, Inc. He further stated that, "the work embodied in this patent establishes the 'drugability' of the Id proteins as targets allowing the Comp...Hoffmann Classic Sterile Wrist Kit
Description:... The hoffmann C-Series Colles Wrist Fixator is now available in a convenient, single-use sterile kit with all the necessary instrumentation. The surgical technique ...ETH Zurich-administered fund ends scientific anonymity
...acknowledge authors, who invest time and knowledge in their contributions," hoffmann says in his article. Clear authorship attribution in this next generati...shing can therefore be enhanced with the advantages of a reputation system. hoffmann describes how a self-regulating reputation system can help to settle editin...New breastfeeding study shows most moms quit early
...reastfeeding happens the least," Forste said. "It's a sad irony both in terms of health needs and the expense these families incur buying formula." hoffmann said the research suggests future efforts to increase breastfeeding rates could target specific communities and not just individual mothers. ...Refusal of suicide order: Why tumor cells become resistant
...occur, this is often caused by tumor cells 'refusing' to take the order to commit suicide," Thomas Hofmann explains. To prevent HIPK2 degradation, hoffmann and his colleagues conducted experiments in which they blocked the Siah-1 enzyme. As a result, HIPK2 was able to accumulate even in cells that were on...'Brains R Us': Neuroscience and education town hall
...ilities. Brains R Us a town hall on the science of educating, from synapse to schoolroom, neurons to neighborhoods takes place in the Frederic de hoffmann Auditorium, at the Salk Institute for Biological Studies. The meeting begins at 8 a.m. and runs through 5 p.m., with lunch included and a reception fo...Balzan Foundation announces 2007 winners
...Paris, for European literature (1000-1500) Bruce Beutler (USA) and Jules hoffmann (France), The Scripps Research Institute, La Jolla, California and Acadmie ...ignment of the Prize for Innate Immunity jointly to Bruce Beutler and Jules hoffmann as follows: "for their discovery of the genetic mechanisms responsible for ...American Chemical Society's Weekly PressPac -- Aug. 15, 2007
...l now, said Thomas Hofmann and colleagues. Everybody thinks that caffeine is the main bitter compound in coffee, but thats definitely not the case, hoffmann said. Only about 15 percent of javas perceived bitterness is due to caffeine, he added, noting that caffeinated and decaffeinated coffee both have sim...Fruit flies and global warming -- Some like it hot
...") has been known to have negative effects on Drosophila. But Loeschcke and hoffmann discovered that it can have advantages too. Flies exposed to heat hardening...res, but the heat hardened flies did poorly on cool days. Loeschcke and hoffmann did field releases with colored flies exposed to different heat hardening t...UW-Madison scientists zero in on drugs' sweet spots
...mer UW-Madison graduate student and post-doctoral fellow and now a chemistry professor at Seattle University; Noel R. Peters, and Professor F. Michael hoffmann of the UW-Madison Comprehensive Cancer Center's Small Molecule Screening Facility; and Ilia A. Guzei, director of crystallography in the UW-Madison de...AngioGenex Reviews 2008 Achievements and Sets Goals for 2009
... AGX51 without any apparent side effects. In the corporate area, Dr. Richard Salvador, the former global head of Preclinical Development at hoffmann La Roche, Inc. became Chairman of the Board of Directors and Dr. Garland, who has led the company's drug discovery and development effort, became the ...AngioGenex Appoints New CEO to Direct Development of Anti-Cancer Drugs
... William Garland PhD as Chief Executive Officer. Dr. Garland, formerly with hoffmann La Roche, Inc., has directed research and development programs for a number...rman of the Board, and the former global head of Preclinical Development at hoffmann La Roche, Inc. Dr. Garland, who designed and directed the pre-clinical st...Pharmasset Appoints Herbert J. Conrad as a Director
...d serves on the Medical Advisory Board of Henry Schein. From 1960 to 1993, Mr. Conrad served in a variety of marketing and strategic planning roles at hoffmann LaRoche, and he was the President of the Roche Pharmaceuticals Division and a Member of the Executive Committee and Board of Directors from 1982 throu...William Garland Joins AngioGenex's New Board of Directors
...r Business Development, who is stepping down as Chairman but will remain on the board. The incoming Chairman added: "After a very productive career at hoffmann La Roche, Inc., Dr. Garland left to run research and development for a number of successful smaller companies such as Centaur Pharmaceuticals, Atairgi...EpiStem Successfully Complete First Year of Mucositis Tests for NIH Biodefence Programme
...alls Chief Executive Officer EpiStem Ltd +44-(0)-161-606-7258 Mike Wort, Anna Dunphy MC Bio-Communications Limited +44-(0)-20-7744-7711 Thilo hoffmann Landsbanki Securities (UK) Limited +44-(0)-20-7426-9000 ...Protein Depletion for Plasma and Serum Proteomic Analysis
...oforms as screening biomarkers of ovarian cancer. Proteomics 2005, 5 :4625-4636.