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Heritable in Medical News

Environmental Toxin Causes Heritable Adult-Onset Diseases

A disease you are suffering today could be a result of your great-grandmother being exposed to an environmental toxin during pregnancy – and you may already have passed it along to your children. // That’s the conclusion reached by researchers at Washington State University, who have found t...

Polycystic ovarian syndrome: New light on its causes and its effect on brothers

...e, such as insulin resistance, diabetes and cardiovascular disease. Our findings are also in accordance with the hypothesis that not only is PCOS is a heritable disease, but that factors associated with it, such as insulin resistance, can be passed down to the next generation of either sex." She said that i...

Five UCSF Scientists Elected to National Academy of Sciences

...ious particles composed of the same protein give rise to markedly different heritable prion states. His work established that strains are "encoded" wit...ith no nucleic acid genome to mutate, it was unclear what could account for heritable strain differences. This year, Weissman's lab reported the development ...

ASHG hosts fourth annual DNA Day essay contest, supports genetics education efforts

... in its manifestation by both our internal and external environments...Both heritable and infectious diseases are strongly influenced by both genetics and the ex...n health." Hartzell concluded her essay by stating that, "Those at risk for heritable diseases strongly influenced by environmental factors, such as cancer and h...

American Cancer Society awards 143 research grants to investigators at 83 institutions nationwide

...ned set of clinical features, such as the number and type of colon polyps. Her work holds the promise of increasing the ability to accurately diagnose heritable neoplastic disorders, predictively test family members, and assess and manage cancer risk. Arul M. Chinnaiyan, M.D., Ph.D., University of Michigan...

Researchers identify personality traits

...ates and delayed onsets of cardiovascular disease, hypertension, and diabetes mellitus. Because personality traits have been shown to have substantial heritable components, the researchers hypothesized that certain personality features may be important to the healthy aging observed in the offspring of centenar...

Study IDs Gene Variants Tied to Sudden Cardiac Death

...ch are located in 10 different gene regions. "It is well-established that prolongation of the QT interval in the general population is a potent and heritable risk factor for sudden death. In addition, QT prolongation results from medications leading to drug-induced cardiac arrhythmias and sudden death. This...

Understanding mental illness through gene-environment interactions

...evoted to fundamental new insights into epigenetics, a field of research devoted to understanding how the environment can produce long-lasting or even heritable changes in gene function without altering the DNA sequence. The study of epigenetics in psychiatry promises several key advances, as noted by Eric ...

States Expand Newborn Screening for Life-Threatening Disorders; New March of Dimes Report Finds State-By-State Gaps Nearly Eliminated

... sweeping advance for public health," said R. Rodney Howell, MD, chairman of the federal Health & Human Services Secretary's Advisory Committee on heritable Disorders in Newborns and Children, (ACHDNC). "The March of Dimes and its chapters nationwide can be proud of their leadership role to essentially el...

UCSF Researchers Use New Tools to Move in on Cancer Susceptibility Genes

...plex systems. The technique has been used to study heritable traits such as obesity and to study the workings o...fferent areas of cancer research or other types of heritable diseases that thus far have been difficult to stud...s of virtually any type of moderately or partially heritable cancer, as well as for other inherited diseases th...
Heritable in Medical Technology

Researchers Create First Targeted Knockout Rats Using Zinc Finger Nuclease Technology

... In a paper published in the July 24, 2009 issue of Science , researchers describe the novel application of ZFNs to generate rats with permanent, heritable gene mutations, paving the way for the development of novel genetically modified animal models of human disease. ZFN technology will make the generat...

Sangamo BioSciences Provides Update on Company's 2008 Progress and 2009 Objectives

...simple, efficient genomic editing. CompoZr(TM) ZFN reagents can be used to efficiently create modified cell lines and model organisms with precise and heritable gene deletions, insertions or modifications using simple, widely used laboratory procedures. This is proven technology with strong potential." ...
Heritable in Medical Definition

Personalized medicine

...pace. Because all cancers require a dysfunction in the DNA of cells that regulate growth, it would be foolhardy not to expect all cancers to have some heritable predisposition as well as environmental influence. Personalized medicine aims to identify these families at risk for cancer , heart disease , dia...
Heritable in Medical Dictionary

Scheie syndrome

...Candler, Savannah Georgia GA, ... Scheie syndrome is one of a number of heritable ... Hide & Seek Foundation, Finding Cures for Children with Lysosom..., treatment and prevention. ... Scheie syndrome is one of a number of heritable mucopolysaccharide storage ... Scheie syndrome is an inherited dis...

Mutation

...the biochemical explaination and scientific logic.... A mutation is a heritable change in the nucleotide sequence of an organism's DNA ... a result, the si...a series of mutations must occur in the same cell. ... Mutation = a heritable change. ... Mutations in your arm or knee cap are not going to get pass...

Ectodermal dysplasia

... Dysplasia to live not only normal life spans, but nearly normal lifestyles. The ectodermal dysplasia (ED) syndromes are a group of about 150 heritable ... The emotional pain of ectodermal dysplasia can be overcome with one's own inner ... The most common form of ectodermal dysplasia usu...

Connective tissue

...ective tissue . ... Fibrous connective tissue is composed of large amounts of closely packed ... What Is Connective Tissue and What Does heritable Disorders Mean? ... Connective tissue is made up of dozens of proteins, including collagens, ... ... common cell type of connective tissu...
Heritable in Biological News

Antioxidant overload may underlie a heritable human disease

Despite the popular notion that antioxidants, such as vitamins C and E, offer health-promoting benefits by protecting against damaging free radicals, a new study in the August 10 issue of the journal Cell reveals that, in fact, balance is the key. The researchers show in mice that an overload of n...

Flow of potassium into cells implicated in schizophrenia

...r disordered tuning of circuitry a phenomenon previously implicated in schizophrenia. Showed significantly decreased volume in the hippocampus a heritable trait in anatomical MRI scans. In addition, Isoform 3.1: Showed levels 1,000 times lower in the heart than the other main form of KCNH2...

New nucleotide could revolutionize epigenetics

...experiences, such as the type of care a rat pup receives from its mother, can also result in methylation patterns and corresponding behaviors that are heritable for several generations. Thousands upon thousands of scientific papers have focused on the role of 5-methylcytosine in development. The discovery...

Ali Shilatifard and colleagues aim to clarify the definition of 'epigenetics'

...nition of "Epigenetics" a rapidly growing research field that investigates heritable alterations in gene expression caused by mechanisms other than changes in D...d three categories of signals that operate in the establishment of a stably heritable epigenetic state. The first is a signal from the environment, the second i...

Common gene variants influence risk factor for sudden cardiac death

...the heart to the end of electrical relaxation. "It is well established that prolongation of the QT interval in the general population is a potent and heritable risk factor for sudden death," said Christopher Newton-Cheh, MD, MPH, of the Massachusetts General Hospital (MGH) Center for Human Genetic Research an...

States expand newborn screening for life-threatening disorders

...is a sweeping advance for public health," said R. Rodney Howell, MD, chairman of the federal Health & Human Services Secretary's Advisory Committee on heritable Disorders in Newborns and Children, (ACHDNC). "The March of Dimes and its chapters nationwide can be proud of their leadership role to essentially el...

Rethinking the genetic theory of inheritance

...ealth (CAMH) have detected evidence that DNA may not be the only carrier of heritable information; a secondary molecular mechanism called epigenetics may also ac...ns to dizygotic (genetically different) twins. A trait or disease is called heritable if monozygotic twins are more similar to each other than dizygotic twins. I...

Studies examine genetic determinants of ADHD

... efficacy of ADHD medications, these treatments are not curative and leave patients with residual disability. Because ADHD is also has one of the most heritable of psychiatric disorders, researchers have been searching for genes that underlie the disorder in the hopes that gene discovery will lead to better tr...

International public-private partnership offers new paradigm for medicinal chemistry

... Oxford. The initiative could offer a new model for future interactions between academia and industry. The study of epigenetics tries to understand heritable changes in gene function that occur without a change in the DNA sequence. This signalling is thought to influence the timing, amount and type of prote...

Call Stephen Michnick a gene grammarian

...have to specific diseases. The study provides insight into the fundamental mechanisms of epigenetic control gene expression that are controlled by heritable but potentially reversible changes in DNA which provides a new avenue towards understanding environmental effects on the human genome. "Epigeneti...
Heritable in Biological Technology

OMT announces a breakthrough in the development of a novel human antibody platform

... in the July 24th issue of Science . The creation of rats with permanent, heritable genetic mutations is a critical milestone in the development of OMT's novel... zebrafish embryos, but this is the first example of successful, permanent, heritable gene-editing in a mammal. ...

Sigma-Aldrich Launches Breakthrough Genome-Editing Tools

...c Finger Nuclease Platform enables Precise, Permanent, and heritable Modification of the Genome ST. LOUIS, Sept. 16 /PRNewswire-FirstCall/ -- ... a rapid, single-step procedure, resulting in cell lines with permanent and heritable gene deletions, insertions, or modifications. Additionally, Sigma-Aldrich i...

Biolistic Gene Transfer to Generate Transgenic Schistosomes, Rev A

...chiedlmeier B et al., Nuclear transformation of Volvox carteri, Proc Natl Acad Sci USA 91, 50805084 (1994) Tavernarakis N et al., heritable and inducible genetic interference by doublestranded RNA encoded by transgenes, Nat Genet 24, 180183 (2000) Williams RS et al., I...

RNA Interference and Gene Silencing: History and Overview

....nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9875855&dopt=Abstract">Abstract ) Kennerdell JR, and Carthew RW. (2000) heritable gene silencing in Drosophila using double-stranded RNA. Nature Biotech 18 : 896-898. (

True-breeding

...red with another true breeding organism for the same traits. In other words, to "breed true " means that two organisms with a particular, heritable phenotype produce only offspring with that... (Redirected from Breeding true ) Jump to: navigation, search ... farm animals also have ...

Trait

...it . trait , traits . trait , traits . traits ... A visible trait is the final product of many molecular and biochemical processes. ... The heritable unit that may produce a trait is called a gene. ... The various aspects of the trait are precisely described: gradations and ... That, in sum, ...

Selection

...viduals with advantageous or "adaptive" traits tend to be more successful than their peers... Natural selection is the process by which heritable traits that make it more likely for an organism to survive and successfully reproduce become more common in a population over successive generations...

Random mating

...ortative mating have the effect, respectively, of reducing and increasing the range of variation, or trait variance, when the assorting is cued on heritable traits.... Random Mating . In a population at equlibrium, mating must be random . ... individuals than you would expect in a population w...

Phenotypic variance

... Phenotypic variation (due to underlying heritable genetic variation) is a ... Without phenotypic variation, there would be no evolution by natural selection. ... In genetics, Heritability is ...

Penetrance

...netrance ? Meaning of penetrance medical term. What does penetrance mean? ... penetrance /pen·e·trance/ (pen'ĭ-trins) the frequency with which a heritable ... A new study calculates the odds of developing Huntington's Disease with reduced penetrance range CAG counts. ... an age of onset curve and p...

Neo-darwinism

...o -Darwinists," came to the ... Encyclopedia information on Neo - Darwinism ... Neo - Darwinism postulates that natural selection acts on the heritable (genetic) ... mony of Neo - Darwinism . Each has significance for a revised view ... Neo - Darwinism . 57. by differentially preserving those ran...

Natural selection

... Natural selection is the process by which heritable traits that make it more likely for an organism to survive and successfully reproduce become more common in a population over successive generations...

Mutation

...A sequence! ... A mutation is any spontaneous heritable change in DNA sequence that contributes ... A ne...It is subject to a variety of different types of heritable change ( mutation ) ... With a nonsense mutati...l mistake rate) about one in ... Mutation = a heritable change. ... Mutations in your arm or knee cap ar...

Genetic testing

...sis when a particular ... Aetna considers genetic testing medically necessary to establish a molecular ... Aetna covers genetic testing for heritable disorders in non-Aetna members when ... A Basic Guide to Genetic Testing . When you see this symbol, click ... What is genetic testing ? ... ...
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Breaking Medicine News(10 mins):Health News:Horse Sense & Sensitivity, Jacksonville Non-profit, To Hold 2nd Annual Round-Up 2Health News:Highlights from The North American Menopause Society 25th Annual Meeting 2Health News:Highlights from The North American Menopause Society 25th Annual Meeting 3Health News:Plastics' Chemical May Affect Baby Boys' Genital Development 2Health News:Plastics' Chemical May Affect Baby Boys' Genital Development 3Health News:FDA Approves New Vaccine to Protect Against Meningitis 2Health News:Prostate cancer medications linked with increased risk of heart-related deaths in men with cardiovascular problems 2
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Breaking Biology News(10 mins):SIR 2015: Interventional radiology shapes tomorrow's medicine 2Geneticist and humanitarian: Prof. Mary-Claire King receives Lasker Award 2BGI Tech and Hebei Agricultural University complete the genome sequencing of the jujube tree 2
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