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Hepatic in Medical News

Are imaging features of hepatic angiomyolipoma related to its clinical setting?

This study consisted of 10 patients (three male and seven female) with hepatic angiomyolipoma, with a mean age of 55.1 years (age range, 19-78 years). Of these patients, dynamic contrast CT showed hepatic angiomyolipoma as a hypervascular mass with intratumoral fatty density, absence of a capsule,...

Cathepsin B increases apoptosis in fulminant hepatic failure

The traditional view is that hepatocyte necrosis is the main feature of fulminant hepatic failure, but increasing evidence implicates a dominant role for hepatocyte apoptosis in this pathogenesis. It is not known if cathepsin B-mediated hepatocyte apoptosis is involved in the pathogenesis of fulmi...

May hepatic granulomas be part of the histological spectrum of chronic hepatitis C?

While older large series of patients with hepatic granulomas have found sarcoidosis and tuberculosis to be the most common causes of hepatic granulomas, recent works have noted some patients with chronic hepatic C and hepatic granulomas and no other obvious associations. Today, patients that under...

Stem cells from umbilical cord used in the treatment of hepatic diseases

This release is available in Spanish . Scientists of the University of Granada, in collaboration with the University of Len, have confirmed that stem cells from human umbilical cord blood can be an appropriate therapy for the treatment of hepatic diseases such as hepatitis, and therefore ...

Hyperion Therapeutics Announces Enrollment of First Patient in Phase 2 Clinical Trial in Patients With Hepatic Encephalopathy

SOUTH SAN FRANCISCO, Calif., Feb. 25 /PRNewswire/ -- Hyperion Therapeutics, Inc. today announced that the first patient has been enrolled in a Phase 2 clinical trial of AMMONUL(R) (sodium phenylacetate and sodium benzoate) Injection 10%/10% in patients with Grade III or IV hepatic encephalopat...

Colon cancer patients benefit from Hepatic Arterial Infusion Therapy

A new study conducted by Nancy E. Kemeny, MD, an Attending Physician in the Department of Medicine at Memorial Sloan-Kettering Cancer Center// said that patients whose colorectal cancer has spread to the liver fared better by receiving hepatic arterial infusion (HAI). In this technique chemotherap...
Hepatic in Medical Technology

Schering-Plough Expands Vicriviroc Phase II Study in Treatment-Naive Patients With HIV

..., long-term tolerance may be limited by the toxicity specifically associated with nucleosides, which can include neuropathy, myopathy, renal toxicity, hepatic steatosis, lactic acidosis, bone marrow suppression, fat atrophy and, with certain agents, increased risk of myocardial infarction.(5-7) ...

FDA Advisory Committee Votes in Favor of Zyprexa for Two Adolescent Indications

... treated with Zyprexa were similar to those seen in adults. The incidence and magnitude of changes in weight, prolactin, triglyceride, cholesterol and hepatic enzyme levels were greater in adolescents than adults. Sedation was also more common in adolescents than adults. "Because weight gain and some of...

Data Demonstrated ACTEMRA(R) (tocilizumab) Significantly Inhibited Progression of Structural Joint Damage in Rheumatoid Arthritis Patients

...increased ALT. Increases in liver enzymes (ALT and AST) were seen in patients; these increases were generally mild and reversible, with no evidence of hepatic injuries. Laboratory changes, including increases in lipids (total cholesterol, LDL, HDL, triglycerides) and decreases in neutrophils and platelets, w...

Study Results Present Efficacy and Safety Findings from the PHIRST-1 Study of Patients with Pulmonary Arterial Hypertension Taking Tadalafil Tablets Once Daily

...at require treatment with ritonavir, dosage adjustments are required. Certain populations of PAH patients such as those with mild-to-moderate renal or hepatic impairment or those taking the drug ritonavir should use a dose of 20 mg daily when beginning therapy with ADCIRCA. Use of ADCIRCA with potent inducer...

Isis Highlights New Data on Antisense Drugs to Treat Type 2 Diabetes and Obesity at ADA Scientific Sessions

...F. Murray, S.L. Booten, X.X. Yu, L.M. Watts, B.P. Monia, S. Bhanot. Antisense Reduction of RBP4 Expression Causes a Marked Improvement in hepatic and Peripheral Insulin Sensitivity and Improves Cardiac Glucose Uptake in Diet-Induced Obese Mice Authors: P. Manchem, X.X. Yu, S.L. Booten, L...

Enrollment in Delcath's Pivotal Phase III Metastatic Melanoma Clinical Trial Achieves Seventy-Five Percent Accrual

...EW YORK, June 8 /PRNewswire-FirstCall/ -- Delcath Systems, Inc. (Nasdaq: DCTH ), a medical technology company testing its proprietary percutaneous hepatic perfusion (PHP(TM)) system for the treatment of cancers of the liver, announced today that it has achieved the seventy-five percent enrollment point o...
Hepatic in Medical Products

Erythropoietin RIA Test

Description:...ajor site of EPO production [1, 2, 3]. Postnatal production occurs primarily in the renal tubular epithelium, although significant continued postnatal hepatic production has been demonstrated [4]. EPO is secreted into the circulation from where it is taken up by target tissues. EPO binds to specific cell mem...
Company:Diagnostic Systems Laboratories, Inc.

Lyphochek Immunology Plus Control

Description:... Lyphochek Immunology Plus Control is an assayed control for monitoring chemistry procedures that test for autoimmune, anemic, malignant, hepatic and nephrotic-disease states. Available in two levels....
Company:Bio-Rad Laboratories

Insulin RIA Test

Description:...e which significantly lowers blood glucose levels. In response to a number of stimuli, including glucose and amino acids, insulin is secreted into the hepatic portal circulation [1,2]. Although 50% of the insulin is removed initially by the liver, the remainder enters the general circulation and is carried t...
Company:Diagnostic Systems Laboratories, Inc.

RxDrugs™: Drug Dosing Tool Special Mobile/Desktop Bundle

Features:...d name - all derived from the trusted AHFS database Informative monographs with the latest information on indications and dosage (including renal and hepatic dosage adjustments) as well as sections on pregnancy, breastfeeding and comparative pricing New integrated dosing calculators, with nearly 400 buil...
Company:Skyscape, Inc.
Hepatic in Medical Definition

Hy's Law

... Hy's law is prognostic indicator that a pure Drug -Induced Liver Injury (DILI) leading to jaundice, without a hepatic transplant , has a case fatality rate of 10% to 50%. The law is based on observations by Hy Zimmerman , a major scholar of drug-induced liver injury. ...
Hepatic in Medical Dictionary

Hepatic

The hepatic arteries supply arterial blood to the liver, accounting for the ... The central veins coalesce into hepatic veins, which leave the liver and empty ... Hepatic encephalopathy is a potentially-reversible neuropsychiatric abnormality in the setting of liver failure, whe...

Wilson disease

..., often leading to lengthy ... Overview: Wilson disease is a rare autosomal recessive inherited disorder of copper metabolism. ... Consider hepatic Wilson disease in the differential ... Diagnosis of Wilson disease depends upon the detection of low serum copper and ... Wilson dis...

Vein

... For other uses, see Vein (disambiguation) ... Examples of such systems include the hepatic portal vein and hypophyseal portal system. ... vein n. Anatomy. Any of the membranous tubes that form a branching system and carry blood ...

Uremia

...sisted, and now mean ... These drugs are the only therapeutic agents that are truly societal drugs, ... presence of remote infection, uremia , hepatic disease, kidney disease and ... List of 61 causes of Uremia , alternative diagnoses, rare causes, misdiagnoses, patient stories, and much mo...

Pku

... Phenylketonuria ( PKU ) is an autosomal recessive genetic disorder characterized by a deficiency in the enzyme hepatic phenylalanine hydroxylase. :541 This enzyme is necessary to metabolize the amino acid phenylalanine to the... Online resource that offe...

Pkd

...n and by obtaining data and information which will benefit those working ... ... by Autosomal Recessive Polycystic Kidney Disease and Congenital hepatic Fibrosis ... RENOWNED PKD EXPERT & RESEARCHER JOINS THE ARPKD/CHF ALLIANCE'S ... PKD cysts can reduce kidney function, leading to kid...
Hepatic in Biological News

Ocera Therapeutics licenses novel treatment for acute hepatic encephalopathy from UCLB

LONDON and SAN DIEGO, April 2, 2009 University College London Business PLC (UCLB) and Ocera Therapeutics Inc., a privately held biopharmaceutical company, announced the signing of an exclusive worldwide licensing agreement for UCL-L1V and all assets and technologies related to the compound for th...

Mitochondrial cholesterol makes response to chemotherapy difficult in hepatic cancer

This release is available in Spanish . Cancer is a disease characterised by important metabolic alterations. Not only these adaptative changes give higher proliferative capacity to cancer cells, but they also contribute to higher resistance to chemotherapeutic agents. The research group led...

Empire State Stem Cell Board awards $12.7 million to Albert Einstein College of Medicine

..., M.B., B.S., professor of medicine; genetics $1,080,000 Amelioration of hepatic metabolic defects by stem cell-derived human hepatocytes. Jeffrey E. Pes... of medicine; microbiology & immunology $1,069,157 Roles of microRNAs in hepatic stem cell differentiation; transcriptional control of cancer stem cells in ...

Internationally acclaimed researcher joins UH faculty thanks to $5.5 million grant

... on other nuclear hormone receptors lends itself to new treatments for metabolic syndrome, including atherosclerosis, Type 2 diabetes and nonalcoholic hepatic steatosis, also known as fatty liver. He also has found evidence that the roles played by estrogen receptors and nuclear hormone receptors in the brai...

Studies on imaging and tracking transplanted cells

... fetal hepatocytes, the researchers for the first time imaged in vivo human hepatic progenitor cells transplanted into a rodent model. "Our results, confirme...promising approach for repeatedly and noninvasively monitoring transplanted hepatic cells," said Zern. Contact: Dr. Mark A. Zern, Transplant Institute, UC Da...

US Air Force grant targets medical evacuation procedures

...epresentative of traumatic military combat injuries: controlled hemorrhage, hepatic ischemia reperfusion and scald/burn. The controlled hemorrhage model, ch... but doesn't reach a field hospital to receive fluids for several hours. hepatic ischemia reperfusion model represents a patient who needs serious abdominal...
Hepatic in Biological Technology

Ocera Therapeutics Presents Data on AST-120 in Patients With Hepatic Encephalopathy at the European Association for the Study of Liver Disease Annual Meeting

The Company also Initiates the Phase 2b ASTUTE Clinical Trial for Mild Hepatic Encephalopathy SAN DIEGO, April 28 /PRNewswire/ -- Ocera Therapeutics, Inc., a privately held biopharmaceutical company, announced that data from its phase 2 study of AST-120 for the treatment of patients with low-...

EMcision Announces 510(k) Clearance of the Habib EndoHPB, its Novel Bipolar RF Device for the Palliation of Biliary and Pancreatic Tumours

...om its use in clinical settings throughout Europe. The Company's first product, the Habib™ 4X™, captured close to 30% share of the US hepatic resection market following its introduction under exclusive license to AngioDynamics (NASDAQ: ANGIO). "We expect similar success with the EndoHPB...

Delcath Enters Agreement to Sell 869,565 Units

...NEW YORK, June 10 /PRNewswire-FirstCall/ -- Delcath Systems, Inc. (Nasdaq: DCTH ), a medical technology company testing its proprietary Percutaneous hepatic Perfusion (PHP(TM)) System for the treatment of cancers of the liver, today announced that it has entered into a definitive agreement to sell 869,565 ...

Delcath Systems Granted Third Orphan Drug Designation

...LOGO ) Delcath is enrolling patients in a Phase II clinical trial testing its proprietary drug delivery system, known as the Delcath Percutaneous hepatic Perfusion ("PHP") System(TM), with ultra-high doses of the drug melphalan for the treatment of neuroendocrine tumors metastatic to the liver. The tri...

Centocor Ortho Biotech Data to be Presented at American Society of Clinical Oncology (ASCO) Annual Meeting

...k of infusion reactions Severe myelosuppression may occur DOXIL dosage should be reduced in patients with impaired hepatic function Accidental substitution has resulted in severe side effects. Do not substitute for doxorubicin HCl on a mg per mg basis ...

Boston Scientific's SpyGlass(R) Direct Visualization System Featured in Broad Range of Clinical Studies at Upcoming Digestive Disease Week(R)

...or the SpyGlass System, as well as the broad range of endoscopic innovations showcased at DDW." Previously available for use only in the bile and hepatic ducts, Boston Scientific recently received clearance from the Food and Drug Administration to market its SpyScope(R) Access and Delivery Catheter for ...
Hepatic in Biological Definition

Diabetes mellitus

...ressure , elevated cholesterol levels , coronary artery disease , past gestational diabetes , polycystic ovary syndrome , chronic pancreatitis , hepatic steatosis (fatty liver), cystic fibrosis , several mitochondrial neuropathies and myopathies, myotonic dystrophy , Friedreich's ataxia , some of t...

Lipase

...ypes of lipases are found in the human body , including pancreatic lipase, hepatic lipase, lysosomal lipase, hepatic lipase, gastric lipase, endothelial lipase, as well as various different ph...

Liver

... related to the liver often start in hepato- or hepatic from the Greek word hepar for "liver". ...liver is supplied by two major blood vessels: the hepatic artery and the portal vein . The hepatic artery normally comes off the celiac trunk . The ...

Malaria

...ing at dusk and during the night, the sporozoites enter the person's body via the mosquito's saliva, migrate to the liver where they multiply within hepatic liver cells. They then turn into merozoites which then enter red blood cells . There they multiply further, periodically breaking out of the red bl...

Urea cycle

...born errors of metabolism ), and in liver failure . The result in liver failure is accumulation of nitrogenous waste, mainly ammonia, which leads to hepatic encephalopathy . Reactions of cycle: NH 3 (ammonia) + CO 2 + 2 ATP → carbamoyl phosphate + 2 ADP + P i ( catalyzed by carb...
Hepatic in Biological Dictionary

Venules

... . Venules pool together to form larger ... Abstract and Introduction: hepatic vein thrombosis should be suspected when ascites, liver enlargement, ... occlusion of hepatic venules to fatal Budd-Chiari ... ... venous system contains small ve...

Renal veins

... possible ... Cindy A. Owen, RDMS, RVT<br> Diagnostic Ultrasound Services at Baptist Memorial ... B. Color Doppler shows flow within the IVC, hepatic veins and renal artery. ... <em>Nicole A. Mah</em>, Department of Urology; <em>Jeko M. Madjarov</em>, Department of ......

Renal portal system

... In human anatomy, the hepatic portal system is the system of veins comprised of the hepatic portal vein and its tributaries. It is also call... arteries iliac arteries. III. VENOUS SYSTEM . hepatic portal system : ... Renal portal system : ...

Polysome

...ranslation, polysome , exon junction complex ... mRNA polysome association. ... We also examined the polysome distribution of the 5′-6bs ... hepatic polysome profiles vary in untreated rats as a function of time of day. ... Regulation of polysome aggregation in a cell-free system through amino...

Lobule

...o a lobule , which is a clear division only visible histologically. A hepatic lobule is a small division of the liver defined at the histological s... lobule usage ... Within each lobule , hepatocytes are arranged into hepatic cords separated by ... The Liver Lobule , from Blue Histology (Copyright L...

Inferior vena cava

...jects into inferior vena cava (IVC) creating apparent low ... Neither hepatic nor infrahepatic inferior vena cava is visualized on this ... Brit...ography ... The normal inferior vena cava at the renal level to the hepatic level was not visualized. ... Definition of inferior vena cava in ...
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(Date:4/17/2014)... in benign prostate tissue was associated with high-grade, ... found even in those with low prostate-specific antigen ... Cancer Epidemiology, Biomarkers & Prevention , a ... , An analysis of prostate tissue biopsies collected ... the Prostate Cancer Prevention Trial (PCPT) found that ...
(Date:4/17/2014)... Scientists have identified new pain relief targets that ... pain. BBSRC-funded researchers at King,s College London made ... nerves in the periphery of the body. , ... and identifying mechanisms underlying pain generation and our ... related side effects." , One potential side effect ...
(Date:4/17/2014)... the April issue of Experimental Biology and ... Drs. Rex Gaskins and Paul Kenis in the ... of the University of Illinois Urbana-Champaign describe their ... reactions underlie a variety of cell functions including ... these crucial roles in regulating normal cellular behavior, ...
(Date:4/17/2014)... in the April issue of Immunity , Kevin ... Medical Research, says it,s time to take a fresh ... sepsis, which kills millions worldwide every year, including ... released into the bloodstream to fight an injury or ... for maintaining good health without inflammation, wounds and ...
(Date:4/17/2014)... April 17, 2014U.S. military personnel who served in ... concussive traumatic brain injury (TBI) were compared to ... other medical reasons. Differences in measures of overall ... months after injury are reported in an article ... journal from Mary Ann Liebert, Inc., publishers. The ...
Breaking Medicine News(10 mins):Health News:Chronic inflammation may be linked to aggressive prostate cancer 2Health News:Chronic inflammation may be linked to aggressive prostate cancer 3Health News:New pain relief targets discovered 2Health News:Live cell imaging reveals distinct alterations of subcellular glutathione potentials 2Health News:Feinstein Institute researcher publishes new perspective on sepsis 2Health News:Long-term effects of battle-related 'blast plus impact' concussive TBI in US military 2
(Date:4/17/2014)... A new modeling study suggests that fish consumption ... infant exposure to long-lived contaminants like persistent organic ... a team of researchers including University of Toronto ... Wania, looks at how different levels of environmental ... behavior of chemicals in the body influenced exposure ...
(Date:4/17/2014)... A Kansas State University engineer has developed ... remotely detects improvised explosive devices. The same technique ... Dunn, the Steven M. and Kay L. Theede ... and nuclear engineering, and his research team have ... underground or in car trunks. The distance detection ...
(Date:4/17/2014)... Several parasites and pathogens that devastate honeybees in Europe, ... Africa, but do not appear to be impacting native ... team of researchers., The invasive pests include including ... East African honeybees appear to be resilient to these ... used to control pests in Europe, Asia and the ...
Breaking Biology News(10 mins):Fish consumption advisories fail to cover all types of contaminants 2Patented research remotely detects nitrogen-rich explosives 2East African honeybees are safe from invasive pests… for now 2East African honeybees are safe from invasive pests… for now 3
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