Embryonic Stem Cells Treated With Growth Factor Reverse Hemophilia In Mice: UNC Researchers
University of North Carolina at Chapel Hill researchers have made a discovery that may have implications for the treatment of liver-based genetic defects such as hemophilia A and B in humans. Mouse embryonic stem cells treated in culture with a growth factor and then injected into the liver reverse a form of hemophilia in mice analogous to hemophilia B in humans, the new study shows. A re...Gene therapy advance treats hemophilia in mouse models
Vector improved in two ways creates a sustained, partial correction to bleeding problems in mice Researchers at the University of Iowa Roy J. and Lucille A. Carver College of Me...Ancient DNA helps UF researchers unearth potential hemophilia therapy
A cut can be life-threatening for people with hemophilia, whose bodies don't produce enough of a protein that prevents prolonged bleeding. Now University of Florida researchers may be one step closer to finding a safe way to spur production of this missing protein in patients with the most common form of the hereditary bleeding disorder. Using a dormant strand of DNA that has quietly exist...Gene Therapy shows promise in treating Hemophilia
Researchers at Beth Israel Deaconess Medical Center reported in the current New England Journal of Medicine that an experimental Gene Therapy method has safely introduced new genes into six men suffering from hemophilia. This method shows signs of helping these men fight the disease by producing the blood clotting protein they lack. None of the patients suffers side effects even after one year...Patients With Severe Hemophilia At Risk Of Developing Osteoporosis
A new study suggests that children with hemophilia arthropathy, a severe form of hemophilia that causes joint pain and swelling, are more at risk // than other children for developing osteoporosis in their later years. But there is hope in preventing osteoporosis from hitting these children, say researchers. Hemophiliac children are now encouraged to do more impact activities than was...Hemophilia Can Be Reduced Through Awareness And Proper Treatment
Even as the country focuses on headline-grabbing diseases, hemophilia, a little known blood disorder, is turning out to be a silent killer with over 50,000 people affected. // World Hemophilia Day is observed every April 17 to promote a global effort to secure appropriate care and treatment for a disease that is the oldest known inherited bleeding disorder caused by a defect in the g...Advance in Program for Development of Non-Intravenous Therapy for Hemophilia
Baxter AG and Jerini AG in Germany have announced progress in their collaborative research program to develop a non-intravenous therapy// for the treatment of hemophilia. Extensive in vitro and in vivo analysis has identified several synthetic lead molecules with promising pharmacological properties. "Using our proprietary technology platform, we continue to make important pro...