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Hemochromatosis in Medical News

Leading Blood Centers, LifeSource and Central Blood Bank, Spotlight a Unique Donor Population During National Hereditary Hemochromatosis Awareness Month

CHICAGO, JULY 14 /PRNewswire/ -- According to America's Blood Centers, every two seconds someone is in need of blood - and during the summer season the need is even more profound. In honor of National Hereditary Hemochromatosis (HH) Awareness Month in July, two of the nation's...

Colon cancer risk linked to genes causing Hemochromatosis

A recent study at the University of North Carolina in Chapel Hill that was published in the Jan. 15 Journal of the National Cancer Institute suggests that two genes - C282Y and H63D, which are linked to the iron overload disorder hemochromatosis may also lead to an increased risk of developing colo...

Hyperferritinemia is another surrogate marker of advanced liver disease

... High serum ferritin, being a hallmark of hereditary hemochromatosis , is frequently found in chronic hepatitis C, alcoholic or non-alcoholic steatohepatitis and non-alcoholic fatty liver disease patients . A study in I...

Iron overload: An important co-factor in the development of liver disease in alcoholics

... Alcohol and iron are believed to have a synergistic effect in the development of liver injury. Furthermore, alcohol enhances iron absorption. Primary hemochromatosis is a genetic disorder, mostly resulting from mutations in the HFE gene, with a disturbance in the iron metabolism which leads to iron accumulation tha...

For Rare Blood Disorder, Pumping Iron Is the Cure

...tting is the best available option for people with hemochromatosis MONDAY, Aug. 25 (HealthDay News) -- B...ting is still the preferred means of treatment. hemochromatosis is an inherited disease in which the body becomes ...t sick, some very much so," he said. Hereditary hemochromatosis is one of the most common genetic disorders in the...

UCLA and biotech company develop first blood test to measure key hormone that regulates iron

...ronic disease. When levels are low, too much iron is absorbed from the diet and released into the blood, leading to iron toxicity and conditions like hemochromatosis or iron overload disease. The current tests do not measure hepcidin but instead measure some of its direct and indirect effects on iron and the iron...

Gene Mutation Linked With Risks of Stroke

...er cancer. The disease can also cause diabetes, heart disease, arthritis, and other serious conditions. The study focused on two variations in the hemochromatosis gene - H63D and C282Y. The report published the journal Neurology, says that of all the various combinations of these mutations, only patients with...

Now Fight Iron Disorders With a Drug Against Hypertension

... for General Internal Medicine at the University of Innsbruck. "These effects make nifedipine a promising candidate for a new drug to treat hereditary hemochromatosis and other iron overload disorders." Combining electrophysiology, cell biology and molecular investigations, Weiss and his collaborators found o...

Hemochromatosis Patients' Blood is Safe

... regulations have not promoted blood donation from hemochromatosis patients. "Hemochromatosis patients had no m... blood donations by these patients. If people with hemochromatosis qualify as donors then that could potentially have...ions for blood donation do not prohibit blood from hemochromatosis patients. ...
Hemochromatosis in Medical Products

NGEN HFE ASRs*

Description:...etection of sequences associated with several respiratory viruses. Nanogen offers reagents for detection of three mutations associated with Hereditary hemochromatosis (HH). Reagents include oligonucleotides for the detection of C282Y, H63D, and S65C mutations of the HFE gene. Laboratories may use the reagents to cre...
Company:Nanogen, Inc.
Hemochromatosis in Medical Definition

Family history (medicine)

...ereditary component, many healthy people are now tested early to prevent the symptoms from developing. This has become accepted in cystic fibrosis , hemochromatosis and various other disorders. References ^ Rich EC, Burke W, Heaton CJ, Haga S, Pinsky L, Short MP, Acheson L. Reconsidering the fa...

Hematopathology

...roangiopathic hemolytic anemia , Paroxysmal nocturnal hemoglobinuria ) • Aplastic anemia : ( Acquired pure red cell aplasia , Fanconi anemia ) • hemochromatosis Coagulation / platelets DIC • Hemophilia ( A , B , C ) • Von Willebrand disease • Purpura ( Henoch-Schönlein , ITP , TTP ) ...

Pathology

...roangiopathic hemolytic anemia , Paroxysmal nocturnal hemoglobinuria ) • Aplastic anemia : ( Acquired pure red cell aplasia , Fanconi anemia ) • hemochromatosis Coagulation / platelets DIC • Hemophilia ( A , B , C ) • Von Willebrand disease • Purpura ( Henoch-Schönlein , ITP , TTP ) ...
Hemochromatosis in Medical Dictionary

Hemochromatosis

The term " hemochromatosis " is often associated to iron accumulation associated ... Non-classical hereditary hemochromatosis in Portugal: novel mutations identified ... Hemochromatosis — Comprehensive overview covers symptoms, causes and treatment of this liver disorder....

Neonatal

...days of life, it is called neonatal death. ... Prematurity and its complications cause almost 30 percent of neonatal deaths (2) ... Neonatal hemochromatosis (NH) is a rare condition which occurs while the baby is ... Infants born with neonatal hemochromatosis, an iron storage disorder, ... The neona...

Liver disease

...in which the national organ donation system is organized, some regions, such as the New York tri ... fatty liver disease is clearly ... ... hemochromatosis (HHC), a genetic liver disorder, at Mayo Clinic. ... See all patient stories related to Genetic Liver Diseases . Read all patient stories. ......

Iron Overload

...nd endocrine glands. Learn about hereditary hemochromatosis ( iron overload ) and what causes it, the sympt...ormation written for you to make ... Hereditary hemochromatosis ( iron overload ) is an inherited disorder in w...ich ... The iron overload associated with hemochromatosis can be detected through two blood tests. ... I...
Hemochromatosis in Biological News

Montana State University researchers map iron transport protein

... Conversely, having too much iron, a condition called hemochromatosis, can also hurt the body by releasing destructive free radicals, Lawrence said. hemochromatosis affects about one in every 300 people and is most common in people of northern European ancestry. Left untreated, it can lead to early death, often by...

Europe's most common genetic disease is a liver disorder

... of the genetic iron overload disorder hereditary hemochromatosis (HH) has remained elusive. In a joint effort, rese...ic radicals that lead to tissue damage. Hereditary hemochromatosis is an iron overload disorder that, affecting about...ified a gene, called HFE, that when mutated causes hemochromatosis in mice and humans. But as yet it is unknown in wh...

Putting an old drug to a new use

... for General Internal Medicine at the University of Innsbruck. "These effects make nifedipine a promising candidate for a new drug to treat hereditary hemochromatosis and other iron overload disorders." Combining electrophysiology, cell biology and molecular investigations, Weiss and his collaborators found out...

Iron exporter revealed that may explain common human disorder

...on exporter that functions in key sites of iron absorption and release in the body. The findings suggest that the iron accumulation seen in those with hemochromatosis may stem from a loss of control over iron export through ferroportin, the researchers said. "Iron is essential in the body and abundant in the envi...

Surprising findings reported about iron overload

...en 20,000 people for the group of disorders called hemochromatosis and iron overload. Ronald T. Acton, Ph.D., prof...he massive data arising from the study, called the hemochromatosis and Iron Overload Screening (HEIRS) Study. The stu...the study in 2000, it was known that most cases of hemochromatosis in Caucasians resulted from common mutations in th...
Hemochromatosis in Biological Technology

Rapid, High Throughput Mutation Discovery Using Fluorescent SSCP on the ABI PRISM 3100 and 3100Avant Genetic Analyzers

... S, and Worwood M. A rapid automated SSCP multiplex capillary electrophoresis protocol that detects the two common mutations implicated in hereditary hemochromatosis (HH). Hum Genet . 1999 Jan. 104(1):2935. Ancillary Items 100% w/w glycerol 10xTBE 0.3 N so...
Hemochromatosis in Biological Definition

Diabetes mellitus

...ity-related diabetes", "insulin-resistant diabetes", or "non-insulin-dependent diabetes" (NIDDM). It may be caused by a number of diseases , such as hemochromatosis and polycystic ovary syndrome , and can also be caused by certain types of medications (e.g. long-term steroid use). About 90-95% of all North Ame...

Liver

...sue in the liver, replacing dead liver cells. The death of the liver cells can for example be caused by alcoholism or other toxins, or hepatitis hemochromatosis , a hereditary disease causing the accumulation of iron in the body, eventually leading to liver damage Cancer of the liver (primary hepatoce...
Hemochromatosis in Biological Dictionary

Single-gene disorder

...sive. 1.3 X-linked dominant ... Inheritance of Single Gene Defects - From the The Merck Manual of Diagnosis and Therapy. ... See hereditary hemochromatosis disorder and gene profiles for more ... Monogenic disorder . A disorder caused by mutation of a single gene . ... See also: single - g...

Hereditary

...agic Telangiectasia: Causes and symptoms Diagnosis Treatment Prognosis Prevention Resources Hereditary Hemorrhagic Information about hereditary hemochromatosis from the American Academy of Family Physicians. ... How does my doctor find out if I have hereditary hemochromatosis? ... Hereditary multiple e...
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