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HbA1c in Medical News

Orexigen(R) Therapeutics Announces Second Quarter 2009 Financial Results

...of their body weight after 56 weeks, more than double the 18.9% of patients on placebo (p<0.001). Contrave patients also showed a 0.6% reduction in hba1c from baseline, compared to a 0.1% reduction in placebo. This difference of 0.5% is clinically and statistically significant (ITT, p<0.001). K...

Sex Hormone Protein May Predict Type 2 Diabetes

...pe 2 diabetes risk beyond traditional risk factors," Liu said. "In direct comparison, it significantly outperformed some newer risk predictors such as hba1c (glycated hemoglobin) and C-reactive protein." The researchers also used genetic data to confirm that SHBG may play a causal role in the developme...

Determining Insulin Pump Need for Diabetics

...ramming the pump to adjust basal insulin delivery rates and boluses throughout the day allows for more precise glycemic control, achievement of target hba1c levels, and prevention of long-term complications," Sand said. Demands Patient Skills Sand explained that a concern of health plans about i...

Tight Management of Type 1 Diabetes Worth the Effort

...cent of those in the intensive arm of the DCCT had hba1c levels of less than 7 percent. The EDC trial w...n above normal management was given. Their average hba1c levels at the end of the study were 7.8 percent. ...n the future. Both also pointed out that lower hba1c levels can cause another serious complication -- l...

-Contrave(R) Obesity Research Phase 3 Program Meets Co-Primary and Key Secondary Endpoints; Exceeds FDA Efficacy Benchmark for Obesity Treatments-

... Contrave patients also showed a 0.6% reduction in hba1c from baseline, compared to a 0.1% reduction in pla...risk, food cravings and eating control, as well as hba1c in the COR Diabetes trial. Patients were randomiz...se patients with type 2 diabetes. Measures of hba1c and other measures of glycemic control were ke...

Expert Statement Issued about Lantus(R) Following Recent Publications in Diabetologia

...cent of those diagnosed are not achieving the blood sugar control target of hba1c <7 percent recommended by the ADA. The hba1c test measures average blood glucose levels over the past two- to three-mont...

Weight-Loss Surgery Safe, Effective Type 2 Diabetes Treatment

... were in remission and about 43 percent had improved blood sugar levels. The average fasting glucose level decreased from 146 to 118.5 and the average hba1c (a measurement of glucose levels over time) decreased from about 7.5 percent to around 6.6 percent, the researchers said in a meeting news release. ...

Frost & Sullivan: Self-Monitoring and POC Diabetes Tests Reveal Potential for Significant Growth, Boosting the European Diabetes Diagnostics Market

...development. For instance, limited awareness about hba1c tests is restraining the laboratory market. Howeve... segments are covered in this research: laboratory hba1c testing, self-monitoring blood glucose (SMBG) and ...n A.K. "Efforts are being undertaken to popularise hba1c tests and enhance the adoption rate in POC setting...

Roche to Commence Phase III Trials with Innovative Treatment Designed to Lower Cardiovascular Risk in Diabetes Patients with Recent Heart Attack

...azone. The primary endpoint of dose-dependent reductions from baseline hba1c versus placebo was met and a range of responses observed from -0.36% (95% C...inical trials) demonstrated numerically comparable reductions from baseline hba1c to those observed with pioglitazone (-0.85%, 95% CI: -0.50 to -1.20, P<0...

VIVUS' Qnexa Shows Significantly Improved Blood Sugar Control Through Weight Loss In Patients With Type 2 Diabetes

...sity of Alabama at Birmingham and presenter. "The hba1c reduction seen in this study of Qnexa is significa...ts treated with Qnexa achieved a 1.6% reduction in hba1c (from 8.8% to 7.2%), as compared to 1.1% (from 8.5...ycemic thresholds. Thus, the observed reduction in hba1c in the placebo treated group was the result of mor...
HbA1c in Medical Technology

CV Therapeutics' Anti-Ischemic Agent Ranexa(R) Significantly Reduces HbA1c and Other Markers of Diabetes in MERLIN TIMI-36

- Data confirms safety and HbA1c reductions seen in ischemic patients with diabetes in earlier clinical trials - ORLANDO, Fla., Nov. 6 /PRNewswire-FirstCall/ -- CV Therapeutics, Inc. (Nasdaq: CVTX ) announced today that data from a prospectively identified analysis of 2,220 dia...

Diagnosing Diabetes: Immediate HbA1c Results Improve Glycemic Control

Beth Wegerbauer Contributing Editor According to the American Diabetes Association, the total annual economic cost of diabetes in 2002 was estimated to be $132 billion, or one out of every 10 health care dollars spent in the United States. A chronic disease with no cure, diabetes is a grou...

5-Year Study Published in Diabetologia Demonstrated Long-Term Safety of Lantus(R) Compared to NPH

... blood glucose control. Both groups had comparable hba1c at study end (mean hba1c improved from a baseline of 8.4% and 8.3% to 7.8% ...en groups: : mean age 55, 54% males, mean baseline hba1c 8.4 vs 8.3% (glargine vs NPH) diabetes duration 11...

Sanofi-aventis Stands Behind the Safety of Lantus(R)

...cent of those diagnosed are not achieving the blood sugar control target of hba1c <7 percent recommended by the ADA. The hba1c test measures average blood glucose levels over the past two- to three-mont...

Spherix Announces Positive Phase 2 Study Results

... Preliminary Data Demonstrates Reduction of hba1c Levels With Doses an Order of Magnitude Lower than...The primary endpoint for the study is reduction in hba1c after 6 months on the drug. After 6 months on dru... group experienced an average reduction of 0.3% in hba1c from the...

MacroGenics and Lilly Achieve Targeted Patient Enrollment in PROTEGE, a Global Phase 2/3 Clinical Trial of Teplizumab in Type 1 Diabetes

...4 countries, including the United States. The primary composite endpoint for PROTEGE includes both the patient's total daily insulin usage and his/her hba1c levels at 12 months. Secondary endpoints are evaluated at 24 months. Longer term safety and efficacy data from patients who complete the PROTEGE tria...

Boehringer Ingelheim Unveils Diabetes Pipeline

...ions like metformin. The significant reduction in hba1c levels seen in this trial is encouraging as it ind...formin.(1) The primary endpoint was the change in hba1c from baseline to week 12.(1) Out of the 333 rando...levant and statistically significant reductions in hba1c and fasting blood sugar or fasting plasma glucose ...

Pistachios Offer Protective Benefits Against Heart Disease, Type II Diabetes and Obesity

.... While on each diet intervention, researchers measured the subjects' hba1c (a marker of blood sugar control over the previous three months) as well as...mpared to the full dose muffin group, as well as a significant reduction in hba1c from baseline in the full dose nuts compared to the other two diets. ...

FDA Approves Rapid-Acting Insulin Apidra(R) for Treatment of Children with Diabetes

...ar bound to hemoglobin in the blood. The change in hba1c from baseline to endpoint for Apidra(R) and insulin lispro were similar. The mean hba1c change in the Apidra(R) population was +0.10% (+ o..., with a 95% confidence interval of (-0.24; 0.12). hba1c at baseline was 8.20% (+ or - 1.05) in the glulisi...

Data from One-Year Liraglutide Phase 3 Study Published Online in The Lancet

...eatment-naive patients treated with liraglutide 1.8 mg achieved an average reduction in blood sugar below the American Diabetes Association target for hba1c of less than 7% and maintained this reduction over the 52-week study period. In addition, patients treated with liraglutide had significant weight l...
HbA1c in Medical Products

Afinion HbA1c test

Description: The Afinion HbA1c test and the fully automated Afinion Analyzer, give you reliable facts conveniently available when and where you need them. Advising the patient can be carried out with confidence. The HbA1c Test Cartridge contains all reagents necessary for the measurement of glycated hemoglobin....
Company:Axis-Shield

A1c-Cellular HbA1c Control

Description: A1c-Cellular is the first HbA1c control available with intact red blood cells and tests the entire HbA1c procedure including the lysing of the red blood cell. The product is a ready-to-use liquid control with an open-vial stability of 30 days and a closed-vial stability of six months when refrigera...
Company:Streck

Glycosal HbA1c Tester

Description: Long term complications associated with diabetes continue to have a tremendous impact on the health and quality of life of patients, in addition to the significant economic costs. These complications are known to be associated with elevated levels of blood glucose. The discovery that the level of h...
Company:Provalis

Afinion AS100 Analyzer

Description:... Afinion AS100 Analyzer is designed to enable on-the-spot testing, regardless of the sample type. The hba1c test was launched in December 2004, and the CRP test in May 2005. Assays scheduled for 2005-2006: ACR (albumin:creatinine ratio), PT-INR, hsCRP and Ho...
Company:Axis-Shield

SYNCHRON CX 4 PRO

Description:... specialty testing process dramatically. The SYNCHRON CX4 PRO consolidates DATs, TDMs, esoterics, proteins and other specialty tests, such as thyroid, hba1c and lipids, into one, easy-to-use workstation....
Company:Beckman Coulter, Inc.

SYNCHRON CX® 4 Delta

Description:... Specialty / Drug Clinical System is a random access analyzer that can consolidate Drugs of Abuse, TDM's and other specialty testing, such as thyroid, hba1c and lipids in one convenient system. The CX4 Delta offers a level of automation and flexibility previously unavailable for specialty testing with....
Company:Beckman Coulter, Inc.

Variant II Total GHb Program

Description:...ed and objective assay for the measurement of total glycated hemoglobin using affinity separation technology. The results are reported in standardized hba1c values to assure traceability to DCCT....
Company:Bio-Rad Laboratories

CGMS System Gold Continuous Glucose Monitoring

Description:...anges to medication regimen Evaluation of behavioral modifications affecting glycemic control Patients undergoing erythropoietin therapy because hba1c may be unreliable. ...
Company:Medtronic MiniMed

Synchron

Description:... Synchron Hemoglobin A1c (HbA1c) utilizes two unique cartridges, Hb and A1c, to determine hba1c concentration as a percentage of total hemoglobin....
Company:Beckman Coulter, Inc.

G7 Glycohemoglobin Analyzer

Description:...h at the forefront of diabetes testing in Japan. Now in the United States, Tosohs seventh generation system, the G7 offers advanced automation; stable hba1c results in 2.2 minutes, -thalassemia testing, user-friendly software and a compact size....
Company:Tosoh Bioscience Inc.

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HbA1c in Medical Dictionary

Glycosylated hemoglobin

...obin ; Glycosylated hemoglobin ; Hemoglobin - glycosylated ; A1C; ... hba1c is a test that measures the amount of glycated hemoglobin in your blood. ...A1c; Hemoglobin - glycosylated ; A1C; GHb; Glycohemoglobin; Diabetic ... hba1c is a test that measures the amount of glycosylated hemoglobin in your b...
HbA1c in Biological News

Study shows CGM devices also benefit people with type 1 diabetes

...s people who have achieved excellent control (with hba1c levels below 7 percent) to continue to tightly man..., including eye, kidney, nerve, and heart disease. hba1c is a measure of long term blood sugar control; sta...to the DCCT findings, every one point reduction in hba1c reduces the risk of long-term complications by app...

JDRF-funded clinical trial demonstrates continuous glucose monitoring improves blood sugar control

...ontrol, principally assessed by measurement of the hba1c level. At enrollment into the study, patients had hba1c levels of 7-to-10% (the goal for adults with type ...t for CGM patients 25 years of age or older, whose hba1c levels decreased (improved) during the study by an...
HbA1c in Biological Technology

FDA Approves Ranexa(R) for First Line Anti Anginal Use and Adds New Claims for Reduction of Ventricular Arrhythmias, Bradycardia, New Atrial Fibrillation and HbA1c

- New labeling reinforces strong safety profile of Ranexa - - Conference call scheduled for 8:00 a.m. ET/5:00 a.m. PT - PALO ALTO, Calif., Nov. 6 /PRNewswire-FirstCall/ -- CV Therapeutics, Inc. (Nasdaq: CVTX ) announced today that the U.S. Food and Drug Administration (FDA) has approved a ...

Glenmark's Novel Molecule for Diabetes, Melogliptin to Enter Phase III Trials

...lel group study, Melogliptin significantly reduced hba1c from baseline as compared to placebo with a mean a... In a subgroup of patients with higher baseline hba1c of 8.5%-10%, Melogliptin reduced hba1c from baseline as compared to placebo with a mean a...

Intarcia Therapeutics, Inc. Presents ITCA 650 Phase 1b Study Results as a Late-Breaker at the American Diabetes Association 69th Scientific Sessions

...s impressive reductions in fasting plasma glucose, hba1c and body weight during 28-day treatment NEW O...stantial reductions in postprandial glucose (PPG), hba1c and body weight. (Logo: http://www.newscom....ed consistent dose-dependent reductions. hba1c & Body Weight ITCA 650 ...

Data on VIVUS' Qnexa To Be Presented During Two Podium Presentations at ADA Annual Meeting

...ent and chief executive officer of VIVUS. "In clinical studies to date, Qnexa has demonstrated significant impact on patients' weight, glucose levels, hba1c and other critical cardiovascular risk factors, in patients with and without diabetes. We are delighted that Qnexa data from our previously reported p...

VIVUS Reports First Quarter 2009 Financial Results and Highlights

...hat EQUATE study subjects treated with Qnexa had a significant reduction in hba1c compared to the increase in hba1c observed in the placebo treated subjects. The EQUATE study was designed as ...

Surveyed Experts Indicate That Byetta LAR and Victoza Have Advantages Over Actos in the Treatment of Type 2 Diabetes

...g Agents finds that a drug that is substantially more effective than metformin (Bristol-Myers Squibb/Merck Serono's Glucophage, generics) at reducing hba1c and offers improvements in terms of convenience would earn a 33 percent patient share in type 2 diabetes in the United States and a 30 percent patient...

Isis Initiates Phase 1 Clinical Trial of SGLT2 Antisense Drug

...ntisense inhibitors of SGLT2 effectively reduce target mRNA levels, increase urinary glucose excretion and consequently lower blood glucose levels and hba1c without causing any changes in renal or hepatic function or dangerously low levels of blood sugar known as hypoglycemia. Observations in preclinical s...

Phenomix and Forest Laboratories to Collaborate on Development and Commercialization of Dutogliptin in Diabetes

..., 12-week, 422 patient Phase 2b clinical trial, dutogliptin met all primary and secondary endpoints, including statistically significant reductions in hba1c when administered once-daily in combination with metformin, a glitazone, or metformin and a glitazone for the treatment of Type 2 diabetes. The trial ...

New Data From Head-to-Head Phase 3 Trial Demonstrate That Liraglutide is More Effective Than Exenatide in Treatment of Type 2 Diabetes

... 8.2 8.1 Change in hba1c % (SE) from baseline -1.12* (0.08) -0.79 (0.08) % hba1c <7.0% 54* 43 % hba1c less than or equal to 6.5% ...

Arena Pharmaceuticals Initiates Second and Third Pivotal Trials Evaluating Lorcaserin for the Treatment of Obesity

...5% or greater weight reduction from baseline at week 52 will be the primary efficacy endpoint. Secondary endpoints include changes in serum lipids and hba1c and, in the BLOOM-DM trial, other indicators of glycemic control will also be evaluated. In both of these additional studies, all patients will receiv...
HbA1c in Biological Definition

Diabetes mellitus

...nosis, an elevated glucose bound to hemoglobin , hba1c , of 6.0% or higher (2003 revised US standard); is... in a doctor's clinic is the measurement of blood hba1c levels. This is the ratio of glycosylated red blo...red blood cell lifetime). In the non-diabetic, the hba1c level ranges from 4.0-6.4%; patients with diabetes...

Insulin

...be fatal. A good measure of long term diabetic control (over approximately 90 days in most people) is the serum level of glycosylated hemoglobin ( hba1c ). A shorter term integrated measure (over two weeks or so) is the so-called 'fructosamine' level, which is a measure of similarly glyclosylated prote...
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