Mylan Receives FDA Approval for Additional Strengths of the Antipsychotic Haloperidol
PITTSBURGH, July 20 /PRNewswire-FirstCall/ -- Mylan Inc. (Nasdaq: MYL ) today announced that its subsidiary Mylan Pharmaceuticals Inc. has received approval from the U.S. Food and Drug Administration (FDA) for its supplemental Abbreviated New Drug Application (ANDA) for ...
Olanzapine Long-Acting Injection (LAI) Efficacy and Safety Data Presented at American Psychiatric Association Annual Meeting
... an analysis of PDSS; and a meta-analysis of olanzapine LAI, olanzapine and haloperidol
data. Additionally, a cost-effectiveness simulation analysis comparing olanzapine LAI to risperidone LAI, haloperidol
LAI and oral olanzapine was presented.
The primary o...
Most Newer Antipsychotics No Better Than Older Ones, Just Different
And, only aripiprazole and ziprasidone among the second-generation drugs did not induce more weight gain than the first-generation drug haloperidol
(Haldol), the study found.
Comparing first- and second-generation drugs, Davis's team also found that second-generation drugs produced fewer "extra...
Short-term use of antipsychotics in older adults with dementia linked to serious adverse events
... did not receive antipsychotics, 6,894 were prescribed atypical or newer antipsychotics and 6,894 were prescribed conventional antipsychotics, such as haloperidol
or loxaprine. Among 20,559 older adults with dementia living in nursing homes, 6,853 received no antipsychotics, 6,853 received atypical antipsychotic...
Treatment with an anti-psychotic drug found to cause changes in metabolism earlier than expected
...n the latest study they used 18 male rats which were randomly assigned to one of three groups: (1) those receiving the conventional antipsychotic drug haloperidol
(HA); (2) those receiving the atypical antipsychotic drug olanzapine (OL); or (3) the control (CO) group which did not receive either drug. The medici...
New Drugs No Better Than Older Ones for Schizophrenia
...nger, study finds
FRIDAY, March 28 (HealthDay News) -- Newer, so-called second-generation antipsychotics are no better than the older drug haloperidol
in treating a first episode of schizophrenia, a new study finds.
However, it appears that more patients prefer the newer drugs and are more likely ...
The FDA Warns Consumers Against Purchase of Drugs on Web
...toms such as difficulty in breathing and muscle stiffness. This led to a preliminary examination of these drugs by FDA.
FDA found they contained haloperidol
, the schizophrenia drug.
According to reports, the pills are packaged in plain plastic bags and mailed in envelopes bearing Greek postmarks. Th...
Brain changes in schizophrenia to be analyzed
...of six-month administration of two antipsychotic drugs used commonly in the treatment of schizophrenia and bipolar disorder – clozapine (Clozaril) and haloperidol
(Haldol) – in monkeys. B
The purpose of the monkey studies will be to:
1. Better understand the effects of the two drugs on gene and protein expre...
Mental Hospitals Offer More Problems than Solutions
...igators were startled in December when they observed Patton patients with tardive dyskinesia, a generally irreversible side effect of long-term use of haloperidol
and other psychotropic drugs. Symptoms can include grimacing, tongue protrusion, rapid blinking, and movements of arms and legs.
Hospital staff ...
Ordinary drugs can interfere with death from cardiac problems
...s of such activities are often seen in causing arrhythmias of the heart. Such kinds of drugs are cisapride and domperidone (GI drugs), chlorpromazine, haloperidol
and pimozide (anti-psychotics) and erythromycin and clarithomycin (antibiotics).
The highest level of risk of sudden cardiac death is from admini...
Dainippon Sumitomo Pharma Announces Lurasidone Phase III Data in Patients With Schizophrenia
... of lurasidone (20 mg, 40 mg, and 80 mg/day) did not show statistical differences vs. placebo. This trial is regarded as "failed," or inconclusive, as haloperidol
(10 mg/day), which was included for purposes of assay sensitivity, also failed to distinguish from placebo.
These data showed that lurasidone wa...
Data Presented at the American Psychiatric Association (APA) Annual Meeting Demonstrate Iloperidone's Efficacy and Safety, With Low Rates of Movement and Metabolic Adverse Events
...izophrenia and that iloperidone
is non-inferior to haloperidol
in long-term maintenance measured as time to
relap...0), iloperidone was statistically
non- inferior to haloperidol
in time to relapse (89.8 days with iloperidone
range of iloperidone (4-16 mg/day given BID) to haloperidol
given BID), iloperidone demonstrated ...
New Study Results Show Asenapine More Effective Than Placebo in the Treatment of Acute Schizophrenia
...ine 5 mg twice daily, asenapine 10 mg twice daily, haloperidol
twice daily (active comparator), or placebo f... 5 mg twice
daily, asenapine 10 mg twice daily and haloperidol
versus placebo (-21.3, -
19.4, -20.0 and -14.6, re...y efficacy measures, asenapine 5 mg
and 10 mg, and haloperidol
produced significantly greater reductions in
Acadia Announces Positive Results From ACP-103 Phase II
Schizophrenia Co-Therapy Trial
...ridone plus placebo
(risperidone HD); ACP-103 plus haloperidol
plus placebo (haloperidol arm). The primary endpoi...than 0.0001), a primary endpoint in the study.
arm showed a robust antipsychotic effect and there...
Common treatment for methamphetamine overdose may damage brain cells
The rats in the experiment were injected with either methamphetamine or a saline solution over a period of eight hours. When the rats were given haloperidol
before and nearly halfway through the eight-hour period, Yamamoto and his colleagues noted more than a fivefold rise in base levels of glutamate in th...
Study finds drug may cut down involuntary movements
...ea), as well as changes in personality, behavior, thinking and memory. There are no FDA-approved treatments for the chorea. Anti-psychotic drugs like haloperidol
(Haldol) are commonly used to suppress chorea, but they cause many different side effects. This study shows that tetrabenazine can decrease chorea, a...