Statins don't lower risk of pneumonia in elderly
...o do: lowering cholesterol and risk of heart disease and stroke in people who've had either disease or are at risk for them," said Dublin. Statins are hmg coenzyme A reductase inhibitors, which also include Zocor (simvastatin) and Mevacor (lovastatin). This class of medications lessens inflammation, whic...Research Identifies Predictors for Successful IVF
...rates between the two groups. The study demonstrated that stimulations with hmg are shorter (11.3 days vs. 12.6 days), use more total gonadotropins, and mo... Two studies compared once with twice daily gonadotropin dosing, using both hmg (MENOPUR) and FSH (BRAVELLE). Results of a prospective randomized study of ...New Data Supports Significant Economic and Clinical Value of MENOPUR(R) in IVF
...mized, comparative trial. Fertil Steril 2002; 78(3): 520-528 4. Andersen AN, et al. Clinical outcome following stimulation with highly purified hmg or recombinant FSH in patients undergoing IVF: a randomized assessor-blind controlled trial. Human Reproduction 2006 Dec; 21(12):3217-27. 5. Pl...Low-Density Cholesterol Subfractions: Not all LDL-C Particles are Created Equal
...ction makeup as well. After implementing lifestyle and diet changes, the NCEP recommends the following drug treatments to lower LDL-C and raise HDL-C; hmg CoA reductase inhibitors (statins), bile acid sequestrants, nicotinic acids and Fibric acids. All of these treatments also lower triglyceride levels, ...Flies can turn off their immune response
...g the NF- Bmediated immune response, appear also to participate in its attenuation. In their role as negative regulators, AP-1 and STAT form a complex hmg protein and HDAC, proteins known to be involved in DNA bending and chromatin structure. This complex is then recruited to the promoter regions of NF-B...UT Southwestern researchers find gene mutation that leads to 'broken hearts'
... mutations in genes encoding enzymes in a pathway for synthesis of a small lipid caused this broken heart defect in fruit flies. One of these enzymes, hmg CoA reductase, also plays a key role in the synthesis of cholesterol in humans. In fruit flies, these enzymes are required to generate a small lipid t...Insight into natural cholesterol control suggests novel cholesterol-lowering therapy
...sterol-building process involves more than 25 enzymes, including one called hmg CoA reductase, and many layers of regulatory control, said Russell DeBose-B...orman B. Javitt, and Russell A. DeBose-Boyd: "Insig-mediated degradation of hmg CoA reductase stimulated by lanosterol, an intermediate in the synthesis of...Kowa Company, Ltd. Acquires ProEthic Pharmaceuticals, Inc.
...ely with the company to ensure its future success." The first pharmaceutical product to be launched by the new company will be pitavastatin, a novel hmg CoA reductase inhibitor for the treatment of hyperlipidemia. Pitavastatin is sold in Japan, Korea and Thailand under the brand Livalo(R). Pitavastatin...