HCMV

Also in the March 24 JNCI

...l human cells and tumor cells grown in culture. hcmv has been suspected of causing or promoting cancer,...iferation and immortalization. To learn whether hcmv induces telomerase activity, Dawei Xu, M.D., Ph.D...iploid fibroblasts and malignant glioma cells with hcmv or introduced a copy of the viral immediate early ...

Existing anti-obesity drugs may be effective against flu, hepatitis and HIV

...in many enveloped viral infections and in cancers. hcmv replicates in a variety of human cell types, inclu...resulted in a more than thousand-fold reduction in hcmv replication. C75 (trans-4-carboxy-5-octyl-3-methyl...replication. Influenza A has little in common with hcmv except for its lipid envelope. Extensive clinic...

Virus mimics human protein to hijack cell division machinery

...bles the brakes and hits the gas. Once a host cell is primed toward growth, hcmv takes over and steals the cell's machinery to reproduce itself. The viru...or cell growth. He also sees potential clinical applications down the road. hcmv infection is very common and, though it remains asymptomatic in most people...

Common virus may help doctors treat deadly brain tumors

... According to the researchers, a vaccine targeting hcmv likely would be administered to patients following... with fully functional immune systems, the initial hcmv infection can be symptom-free or it can be associa...ents or those undergoing bone marrow transplant -- hcmv can become reactivated and cause more severe illne...

New Vaccine for CMV Infection

...aid. Researchers at UCSD hope to begin pre-clinical work on development of a human vaccine. If successful, an FDA-approved, commercially licensed hcmv vaccine could be administered to specific at-risk populations, such as females prior to child-bearing years, day care providers, organ transplant reci...

Human Vaccine for Herpes Virus on the Anvil

... Researchers at UCSD hope to begin pre-clinical work on development of a human vaccine. If successful, an FDA-approved, commercially licensed hcmv vaccine could be administered to specific at-risk populations, such as females prior to child-bearing years, day care providers, organ transplant reci...

Pain Killers Keep the Virus Away

...te pain, inflammation and fever. So, scientists wondered if they could keep hcmv from replicating. Suppressing prostaglandins is easy. That's what so-called... In the latest study, Thomas Shenk and his colleagues tried to prevent hcmv replication in human connective tissue cells with a cox-2 inhibitor. When i...

HCMV in Medical Dictionary

Cytomegalovirus

... Cytomegalovirus is a herpes viral genus of the Herpesviruses group: in humans it is commonly known as hcmv or Human Herpesvirus 5 (HHV-5). CMV belongs to the Betaherpesvirinae subfamily of Herpesviridae, which also includes... From the Centers for Disea...

HCMV in Biological News

A viral cloaking device

...us--it thrives but it doesn't affect the host." hcmv is carried by eight in 10 people. Although it gene...ed Kennedy recently had surgery. Understanding how hcmv survives may help in the development of a vaccine,...Yang. She and Bjorkman published their findings on hcmv survival mechanisms in the July 15 edition of Pro...

New vaccine prevents CMV infection and disease in mice

...d. Researchers at UCSD hope to begin pre-clinical work on development of a human vaccine. If successful, an FDA-approved, commercially licensed hcmv vaccine could be administered to specific at-risk populations, such as females prior to child-bearing years, day care providers, organ transplant reci...

HCMV in Biological Technology

RNArticles: RNA Amplification Used to Develop a New In Vitro HCMV Assay

Gene arrays can be used to simultaneously measure the expression levels of thousands of genes in a single experiment. One limitation of this technology is that large amounts of RNA may be required for each array hybridization experiment -- typ...