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HBV in Medical News

Does HBV infection induce acute cellular DNA damage?

Eukaryotic cells employ multiple strategies of checkpoint signaling and DNA repair mechanisms to monitor and repair damaged DNA. There are two branches of the checkpoint response pathway, ataxia telangiectasia-mutated (ATM) pathway and ATM-Rad3-related (ATR) pathway. Virus replication presents the...

Who found some new mechanisms of HBV virulence?

This dreadful HBV is small in size. The genome of this virus is a partial double stranded circle. When made fully double stranded, this genome carries about 3000 base pairs, compared to 200 kilo base pairs of the genome of the smallpox virus. These 3000 base pairs encode an envelope protein, a cor...

HCV and HBV spreading more slowly among injection drug users in San Francisco

Injection drug users are still at a very high risk of acquiring hepatitis C (HCV) and hepatitis B (HBV); however, needle-sharing is less common, and users do not become infected as quickly as they did in the past, according to a new study in the September issue of Hepatology, a journal published b...

Despite Control Efforts HBV Found to Transmit After Dental Surgery

Researchers in the United States have identified the first patient-to-patient transmission of hepatitis B virus (HBV) as a result of dental surgery, despite standard infection// control procedures having been followed. The case report has been published in the Journal of Infectious Diseases ...

JNCI news brief: Hepatitis B virus mutations may predict risk of liver cancer

...er cancer and may help predict which patients with hbv infections are at increased risk of the disease, a...nal Cancer Institute , published online July 2. hbv infection is a known cause of hepatocellular carci...h development of HCC and more prevalent as chronic hbv infection progressed from the asymptomatic state t...

GlaxoSmithKline Travel Health: 55 percent of travellers needlessly put themselves at risk from a potentially fatal virus

...c. as well as through direct transfer of body fluids(9) Many people with hbv (hepatitis B virus) infection have no symptoms while others develop flu-lik...g from accidents or illness while overseas(12) Most new cases of chronic hbv infection, detected in the UK are acquired overseas(4) GlaxoSmithKli...

Cimzia(R) (certolizumab pegol) Now Available for Self-Administration in Adult Patients With Moderate to Severe Crohn's Disease

...ses have been fatal. Evaluate patients at risk for hbv infection for prior evidence of hbv infection before initiating CIMZIA therapy. Exerci...d as carriers of HBV. Patients who are carriers of hbv and require treatment with CIMZIA should be closel...

UCB's CIMZIA(R) (certolizumab pegol) Approved by the U.S. FDA for Adult Patients Suffering From Moderate to Severe Rheumatoid Arthritis

...ses have been fatal. Evaluate patients at risk for hbv infection for prior evidence of hbv infection before initiating CIMZIA therapy. Exerci...d as carriers of HBV. Patients who are carriers of hbv and require treatment with CIMZIA should be closel...

Future for radioembolisation in patients with advanced hepatocellular carcinoma

...the study, said: "In terms of a global strategy, we hope to achieve a major impact on the incidence of HCC through current vaccination strategies for hbv virus infection, screening and treatment for HCV infections, and from the reduction of alcoholic liver disease. However, because the latency period fr...

Do patients at risk for B-cell malignancy need antiviral treatment?

...-cells were detected in the liver of 4 (10%) of 40 HCV-positive patients but were present in only 3 (0.37%) of 808 liver biopsy specimens with chronic hbv infection. Chi-square tesing showed the monoclonal B-cells infiltrating in the liver were more frequent in the HCV-infected patients (P=0.000).A clona...
HBV in Medical Technology

Pharmasset Announces Initiation of Combination Study of Clevudine and Viread(R) for HBV by French National Agency for Research on AIDS and Viral Hepatitis (ANRS)

96-week comparative study of Clevudine versus Viread(R) versus Clevudine+Viread(R) in 150 patients with chronic hepatitis B PRINCETON, N.J., July 8 /PRNewswire-FirstCall/ -- The French National Agency for Research on AIDS and Viral Hepatitis (ANRS), with the support of Pharmasset, In...

Pharmasset Commences Dosing in Phase 3 Registration Studies of Clevudine for HBV

-Two 48-week Superiority Studies versus Hepsera(R) in Patients with Chronic Hepatitis B- -Studies will also Assess Clevudine's Sustained Virologic Response Rate for HBV- PRINCETON, N.J., Oct. 1 /PRNewswire-FirstCall/ -- Pharmasset, In...

SIMPONI(TM) (golimumab) Receives Positive Opinion From CHMP for Once-Monthly Subcutaneous Treatment of Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis

...and monitored prior to the initiation of, during treatment with, and for several months following discontinuation of SIMPONI. In patients who develop hbv reactivation, SIMPONI should be discontinued. Lymphomas have been observed in patients treated with TNF blocking agents, including SIMPONI. The i...

New One-Year Data from REMICADE(R) SONIC Trial Show Sustained Efficacy Compared with Azathioprine in Treatment of Crohn's Disease

... Heart failure - new or worsening symptoms, such as shortness of breath, swelling of ankles or feet, or sudden weight gain. Reactivation of hbv - feeling unwell, poor appetite, tiredness, fever, skin rash and/or joint pain. Liver injury - jaundice (yellow skin and eyes), dark brown uri...

Video: Partnership Unites UCB with Consumer Product Innovator OXO(R)

...ses have been fatal. Evaluate patients at risk for hbv infection for prior evidence of hbv infection before initiating CIMZIA therapy. Exerci...d as carriers of HBV. Patients who are carriers of hbv and require treatment with CIMZIA should be closel...

Pharmasset Initiates First Time in Human Study of PSI-7851 for the Treatment of Hepatitis C (HCV)

...veloping three product candidates. Clevudine, for the treatment of chronic hbv infection, is enrolling Phase 3 clinical trials for registration in North, ... South America, Europe, Japan and Taiwan. Clevudine is already approved for hbv in South Korea and the Philippines. It is marketed in Korea by Bukwang Phar...

Pharmasset Reports Fiscal Year End 2008 Financial Results

...xpenses for clevudine for the treatment of chronic hbv infection, as well as increased drug discovery act...ndidates. Clevudine, for the treatment of chronic hbv infection, is enrolling Phase 3 clinical trials fo...rica and Europe. Clevudine is already approved for hbv in South Korea and marketed by Bukwang Pharmaceuti...

Roche, InterMune and Pharmasset Announce Initiation of INFORM-1, the First Dual-Combination Clinical Trial with Oral Antivirals in Hepatitis C

...eveloping three product candidates. Clevudine, for the treatment of chronic hbv infection, is enrolling Phase 3 clinical trials for registration in North, Central and South America and Europe. Clevudine is already approved for hbv in South Korea and marketed by Bukwang Pharmaceuticals in South Korea under...

CIMZIA(R) (Certolizumab Pegol) Provides Rapid and Sustained Relief from Signs and Symptoms of Rheumatoid Arthritis for Two Years

...ses have been fatal. Evaluate patients at risk for hbv infection for prior evidence of hbv infection before initiating CIMZIA therapy. Exerci...itored for clinical and laboratory signs of active hbv infection throughout therapy and for several month...

CIMZIA(R) (Certolizumab Pegol) Provides Long-Term Benefit Without Dose Escalation in Crohn's Disease Patients

...ses have been fatal. Evaluate patients at risk for hbv infection for prior evidence of hbv infection before initiating CIMZIA therapy. Exerci...itored for clinical and laboratory signs of active hbv infection throughout therapy and for several month...
HBV in Medical Products

Genetic Systems HBsAg EIA 3.0

Description:... Bio-Rad's Genetic Systems™ HBsAg EIA 3.0 screening and confirmatory assays offer outstanding sensitivity and early detection of hbv infection, helping to meet your testing criteria....
Company:Bio-Rad Laboratories

VITROS® Anti-HBs Assay

Features:...BV infection prior to or following vaccination for hbv or when status is unknown Use in diagnosis of hbv diseases associated with hbv infection when used with other serological markers...
Company:Ortho-Clinical Diagnostics
HBV in Medical Definition

Réseau Sentinelles

..., Varicella zoster since 1990, Herpes zoster since 2004, Male urethritis since 1984 and Hepatitis A Virus ( HAV ), Hepatitis B Virus ( hbv ) and Hepatitis C Virus ( HCV ) since 2000 as well as 3 non infectious diseases : Asthma since 2002, Suicidal attempts since 1997 and...
HBV in Medical Dictionary

Liver function tests

...in the interpretation of common blood liver function tests . ... Liver function tests , liver disease, HCV or chronic Hepatitis C, hbv or chronic ... Liver Function Tests . a Simple FactSheet from the AIDS Treatment Data Network ... Liver function tests — Overview cov...

Hepatitis b

... Hepatitis B is a disease caused by hbv hepatitis B virus which infects the liver of hominoidae, including humans, and causes an inflammation called hepatitis . Originally known as &q...

B virus

... virus surface antigen (cured) within one year ... Hepatitis B virus tests look for substances in the blood that show a hepatitis ... hbv DNA testing checks for genetic material (DNA) from the hepatitis B virus . ... ACOG is a nonprofit organization of women's health care phys...
HBV in Biological News

Models simulate nitrate dynamics in Garonne, Southwest France

...nce, using multivariate analysis before applying the linked rainfall-runoff hbv and the Integrated Catchment Model of Nitrogen (INCA-N) models to simulate daily flow and N dynamics. This is the first application of the linked hbv and INCA-N models to a major European river system commensurate with the la...

Weill Cornell science briefs June/July 2008

...compound is being studied in subjects with chronic hbv who have never been treated before by one of the c...polymerase in order to stop the replication of the hbv virus. Dr. Ira Jacobson -- principal investiga...says that the new drug may help many patients with hbv avoid a lifetime of taking drugs to control the in...

BARACLUDE data show low resistance over 5 years in nucleoside-naive hepatitis B patients

...gic breakthrough is defined as a greater than or equal to 1 log increase in hbv DNA from nadir, as measured by the polymerase chain reaction or PCR assay. 2 Undetectable viral load is defined as hbv DNA levels less than 300 copies/mL, as measured by PCR assay. Viral load ...

Nucleonics initiates hepatitis B clinical trial with expressed interfering RNA therapeutic

...he four siRNAs targets a different sequence of the hbv genome, collectively leading to the potential dest...tion or elimination of all RNA species produced by hbv within an infected cell. The result is a potent antiviral effect designed for efficacy against all hbv genotypes, including drug resistant strains. Addit...

Who will recover spontaneously from hepatitis C virus infection

...s, co-infection by hepatitis B virus (HBV) is associated with a higher possibility of self recovery. The investigators suggested that the infection of hbv interferes with the HCV replication, which would finally lead to virus eradiacation.. HCV patients co-infected by hepatitis A virus also have a better...

Liver cancer patients with high serum levels of hepatitis B virus face poorer outcomes

...ever study examining the prognostic value of serum hbv DNA levels for patients with liver cancer undergoi...that patients with high pre-chemotherapy levels of hbv DNA had a significantly increased incidence of sev...www.interscience.wiley.com/journal/hepatology ). hbv is associated with a more than 200-fold increase i...

FDA Approves New Treatment for Chronic Hepatitis B

...illion Americans are chronically infected with the hbv virus. Baraclude slows the progression of chroni...nt improvement in the liver inflammation caused by hbv and an improvement in the degree of liver fibrosis... of Baraclude were of the type typically seen with hbv therapy. They include severe, acute exacerbation o...

Norovirus, AIDS vaccine and Hepatitis Virus

...ns (alpha) is used to treat chronic infection with hbv and HCV. There is a vaccine available to prevent the spread of hbv but not HCV. In the study, a new class of inter...eron lambda, was tested for its ability to inhibit hbv and HCV replication. Results showed 90% inhibition...
HBV in Biological Technology

Cimzia(R) (certolizumab pegol) Provides Long-Term Remission and Response Rates in Infliximab-Refractory Crohn's Patients

...ses have been fatal. Evaluate patients at risk for hbv infection for prior evidence of hbv infection before initiating CIMZIA therapy. Exerci...d as carriers of HBV. Patients who are carriers of hbv and require treatment with CIMZIA should be closel...

ImQuest Presents Data on the Anti-Hepatitis B Virus Activity of Pyrimidinediones at the 13th ISVHLD Meeting in Washington D.C.

...e identified ten pyrimidinediones as inhibitors of hbv replication, with two compounds yielding potent inhibition of hbv replication at sub-micromolar concentration levels...ent of first in class non-nucleoside inhibitors of hbv replication. The data were presented by Todd B. P...

Pharmasset Reports Fiscal First Quarter 2009 Financial Results

...veloping three product candidates. Clevudine, for the treatment of chronic hbv infection, is enrolling Phase 3 clinical trials for registration in North, ...merica and Europe, among other countries. Clevudine is already approved for hbv in South Korea and marketed by Bukwang Pharmaceuticals in South Korea under...

Pharmasset and Roche Obtain FDA Consent to Start a Phase 2b Study With R7128 in Treatment Naive HCV Patients

...veloping three product candidates. Clevudine, for the treatment of chronic hbv infection, is enrolling Phase 3 clinical trials for registration in North, Central and South America and Europe. Clevudine is already approved for hbv in South Korea and marketed by Bukwang Pharmaceuticals in South Korea under...

FDA Approves Most Comprehensive System to Test Donated Blood for HIV, Hepatitis B & Hepatitis C

...cancer in the U.S. More than 1,200,000 people are chronically infected with hbv and about 5,000 people die of complications of HBV every year in the U.S. Many individuals with hbv and HCV show no symptoms of disease, and do not know that they are infected...

New Data Suggest CIMZIA(R) (Certolizumab Pegol) Active in Treating Moderate to Severe Crohn's Patients With Fistulizing Disease

...ses have been fatal. Evaluate patients at risk for hbv infection for prior evidence of hbv infection before initiating CIMZIA(R) therapy. Exe...d as carriers of HBV. Patients who are carriers of hbv and require treatment with CIMZIA(R) should be clo...

Pharmasset to Present at Two Upcoming Investor Conferences

...eveloping three product candidates. Clevudine, for the treatment of chronic hbv infection, is enrolling Phase 3 clinical trials for registration in North, Central and South America and Europe. Clevudine is already approved for hbv in South Korea and marketed by Bukwang Pharmaceuticals in South Korea under...

Pharmasset to Present at the Natixis Bleichroeder Hidden Gems Conference on Monday, October 13th

...eveloping three product candidates. Clevudine, for the treatment of chronic hbv infection, is enrolling Phase 3 clinical trials for registration in North, Central and South America and Europe. Clevudine is already approved for hbv in South Korea and marketed by Bukwang Pharmaceuticals in South Korea under...

Pharmasset to Present at the JMP Securities Healthcare Focus Conference on Monday, October 6th

...eveloping three product candidates. Clevudine, for the treatment of chronic hbv infection, is enrolling Phase 3 clinical trials for registration in North, Central and South America and Europe. Clevudine is already approved for hbv in South Korea and marketed by Bukwang Pharmaceuticals in South Korea under...

Pharmasset Reports Preliminary Results of a 4-week Proof-of-Concept Combination Study of R7128 for the Treatment of Chronic Hepatitis C in Genotype 2 or 3 Non-Responders

...eveloping three product candidates. Clevudine, for the treatment of chronic hbv infection, is enrolling Phase 3 clinical trials for registration in North, Central and South America and Europe. Clevudine is already approved for hbv in South Korea and marketed by Bukwang Pharmaceuticals in South Korea under...
HBV in Biological Dictionary

Hepadnaviridae

...s using novel recombinant baculoviruses which encode ... Hepadnaviridae . Orthohepadnavirus. Hepatitis B virus. Vertebrates. Avihepadnavirus ... hbv is the prototype member of the family Hepadnaviridae : ... Contact us ViralZone Home. Hepadnaviridae . Molecular biology. VIRION. Enveloped, sp...

Encapsidation

... The Heron hbv RNA encapsidation signal epsilon is an RNA struc...e pregenomic RNA required for replication. Duck hbv RNA encapsidation signal epsilon (DHBV) is an element essential for hbv ... Heron...
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