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HAART in Medical News

Need for considering cardiovascular risks before giving HAART for HIV/aids patients

Physicians treating HIV/AIDS patients with highly active antiretroviral treatment (HAART) needs to be careful// of the cardiac risks involved, says researchers from Belgium. Highly active antiretroviral treatment can dramatically improve the quality of a HIV/AIDS patient’s life expectancy. Thi...

The flip side of AIDS cocktails – HAART regime damages live

HIV infected patients on highly active antiretroviral therapy (HAART regime) are forced to stop the treatment because of the toxic side effects of the treatment, which causes liver damage. According to a study led by Dr. Raymond T. Chung, who presented the findings at Digestive Disease Week in Atl...

HIV Patients May Have Stiffer Arteries

...s new insight into the link between HIV infection, haart use and the premature development of cardiovascula...alt treatment, and the study didn't establish that haart causes the stiffness, noted the researchers, from ... studies have found that HIV patients treated with haart had a higher level of arterial stiffness than HIV ...

New Strategy Eyed for AIDS Treatment

...py and what's known as highly active anti-retroviral (HAART) treatments. When HIV viruses hide in immune cells, the researchers explained, existing haart treatments can't reach them. But the study identified where HIV hides in immune cells and the "stealth" mechanisms that enable the virus to elude exis...

New HIV Drug May Help Those Resistant to Therapy

...y active anti-retroviral therapy, which consists of a number of drugs that reduce viral load by stopping the virus from replicating. If it works well, haart can increase recipients' life expectancy, but it's not effective in about 10 percent of people who take it, partly because some develop resistance to ...

HIV Experts Propose New Approach to Eradicate HIV in Latest Issue of Science

...ing the Post-HAART Era Since the arrival of haart more than a decade ago, people diagnosed with HIV ...to live 40-50 years as a result of HAART. However, haart is not the optimal solution for HIV - it requires ... various side effects and the effects of long-term haart are not yet known. And, if...

Long-term HIV treatment may reduce risk for atherosclerosis

...sk factors for atherosclerosis in the general population," said Dr. Kingsley. "The purpose of our study, however, was to investigate whether long-term haart usage was a major risk factor." "These results could be due, in part, to lower lipid values of HIV infected men prior to beginning antiretroviral t...

Study Disproves Belief That Hepatitis C Blunts HIV Drugs

... by HIV -- and whether CD4 cells can rebuild after haart is used to suppress HIV infection. For the study, ... with hepatitis C, we were treating their HIV with haart but didn't always get very good restoration of CD4...ation seen in some HIV/HCV-infected patients after haart may be due to a number of other causes, such as ge...

Researchers disprove long-standing belief about HIV treatment

... with hepatitis C, we were treating their HIV with haart but didn't always get very good restoration of CD4...Years of clinical experience have shown that, with haart treatment suppressing the HIV, CD4 levels are typi...ttribute less than desirable CD4 restoration after haart in co-infected patients to the hepatitis C virus. ...

Death Rates for HIV Patients Decrease Dramatically

... Study found 5-year survival rate for those on haart now equals general population TUESDAY,...important thing to know is that the composition of haart regimen will keep changing for a particular patien...s of action are continuously needed to be added to haart regimen to maintain the low mortality rate." Th...
HAART in Medical Technology

ImQuest Submits Investigational New Product Application to the Food and Drug Administration to Initiate HIV Therapeutic Clinical Trials with IQP-0410

...ents failing long courses of therapy with currently approved RT and protease inhibitors. The compound is well suited for use as a component of primary haart regimens as well as a salvage therapy option. Preclinical studies have also demonstrated the ability of the compound to be used in combination with al...

Pooled-Analysis of 54 Clinical Studies Shows No Increased Risk of Heart Attack With Abacavir Therapy

...ed data from 9,639 subjects on abacavir-containing haart and 5,044 subjects on non-abacavir HAART. Overall,...ation: 2.5 events per 1,000 people in the abacavir haart and 4 events per 1,000 people in the non-abacavir ...t attacks was 1.1 per 1,000 people in the abacavir haart and 1.4 per 1,000 people in the non-abacavir HAART...

Kaiser Permanente - Group Health Study Shows Depression Worsens HIV Treatment

...retroviral therapy (HAART) regimen. The researchers studied the patients' haart adherence, viral loads, and changes in CD4 T-cell counts over a 12-month pe...e-home point of this study is that depression carries a worse prognosis for haart in HIV patients. However, we also found that SSRIs can reverse this and imp...

Insmed Releases Positive Results from Iplex Phase II HIV-Associated Adipose Redistribution Syndrome Clinical Study

...hese features have increased markedly with the advent of highly active antiretroviral therapy (HAART) for HIV. Recent studies performed in subjects on haart suggest nearly 40% of individuals develop the morphologic features characteristic of this syndrome. About IPLEX IPLEX was approved in the United S...
HAART in Medical Definition

Sexual orientation and medicine

...a genetic component to sexual orientation. [3] 1995 Saquinavir , the first protease inhibitor is approved for public use by the FDA . haart radically changes the prognosis of HIV/AIDS . 1996 The US Department of Defense includes homosexuality in a list of "mental disorders," in ...
HAART in Biological News

NIH funds $9.5 million for research on HIV and the human innate immune system

...the researchers' concerns is that prolonged use of haart and/or low level chronic HIV infection may impact ...pression in cells from HIV-infected individuals on haart that impact the cell's cycle and immune responses.... networks affected by chronic HIV infection and/or haart and thereby, better understand the impact of the v...

Potential new HIV drug may help patients not responding to treatment

...f drugs that reduces the viral load by stopping the virus from replicating. haart can increase the life expectancy of an HIV-positive patient substantially i...y, hope their study could ultimately lead to a new treatment that will help haart to work more effectively in these people. In the new study, researchers ...

HIV-1 protease inhibitor induced oxidative stress in pancreatic B-cells: thymoquinone protection

...s in the April 2009 issue of Experimental Biology and Medicine . Although insulin resistance has been clinically observed in HIV-1 patients receiving haart regimen, the molecular mechanisms of this metabolic abnormality have not been delineated. The research team led by Dr. Krishna C. Agrawal, Regents ...

Waking up dormant HIV

... haart (highly active anti-retroviral therapy) has emerge...t keeps virus levels almost undetectable; however, haart can never truly eradicate the virus as some HIV al...active candidate to weed out the hidden virus that haart misses. Matija Peterlin at UCSF and colleagues...

Researchers use chemical from medicinal plants to fight HIV

...hortening, which could make it a key weapon in the fight against HIV. "This has the potential to be either added to or possibly even replace the haart (highly active antiretroviral therapy), which is not tolerated well by some patients and is also costly," said study co-author Rita Effros, a professo...

Efavirenz-based initial therapies associated with better outcomes in HIV-infected adults

...se management program in Africa. Participants were haart nave adults who began nevirapine-based or efvirenz... their purchases of nevirapine- or efavirenz-based haart to estimate adherence to their treatment regimens....nd the frequent use of first-line nevirapine-based haart in such programs the assumption that efavirenz and...

Einstein researchers demonstrate a novel approach to treating AIDS

...n from developing," he says. "But if several days have passed, the virus is able to infect enough cells to cause a chronic HIV infection. By combining haart with radioimmunotherapy, we may be able to prevent lifelong infection in these people by eliminating those initially infected cells." Clinical tri...

HIV-1 kills immune cells in the gut that may never bounce back

...anted to know whether this loss was reversible, and whether giving patients haart during the early infection period helped restore these cells to the GI lini...es report on a trial of 40 HIV-1 positive patients who began treatment with haart shortly after contracting the virus -- during the acute early infection pha...

Human testis harbors HIV-1 in resident immune cells

...ess virus in the blood. The presence of HIV in the semen despite successful haart has intrigued scientists. Researchers led by Dr. Nathalie Dejucq-Rain...ng this organ and may be present at sub-therapeutic levels. Thus, although haart may achieve undetectable virus levels in the blood, virus replication in th...

New study calculates millions of years saved in lives of AIDS patients

...al therapy or HAART). To analyze the impact of haart on patient survival, the investigators used a comp... prevent opportunistic infections. But in the four haart eras spanning 1996 to 2003, per-person survival in...he investigators concluded, widespread adoption of haart regimens, in addition to prophylaxis, led to at le...
HAART in Biological Technology

Sangamo BioSciences Initiates Phase 1 Trial of CCR5-ZFP Therapeutic to Treat HIV/AIDS

...s with HIV will be enrolled in this trial in two treatment cohorts. The first cohort to be treated comprises six subjects who have failed two or more haart (Highly Active Antiretroviral Therapy) regimen. The first three subjects in this cohort will be treated sequentially and monitored for the first 21-da...

According to AlphaDetail, Inc. Merck and Tibotec Therapeutics Lead Among Infectious Disease Specialists

... the conference, the majority of respondents revealed that the most important study indicated a 70% improvement in survival for patients who initiated haart therapy with CD4 counts between 351 and 500 vs. those who initiated at 350 and below. Interestingly, a large percentage of respondents also highlighte...
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