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Glypican in Medical News

BioMosaics' Glypican-3 Antibody (clone 1G12) Validated at PhenoPath Laboratories for Immunohistochemical Detection of Liver Cancer

...ncreasing over the past ten years and is expected to continue to rise over the next decade. Glypican-3, an oncofetal antigen, is a member of the glypican family of GPI-anchored cell-surface heparan sulfate proteoglycans. Many studies have shown that, using the 1G12 antibody, GPC3 is detected at the prot...

Mayo Clinic identifies treatment target for liver cancer recurrence and survival

...ding of a specific growth factor, fibroblast growth factor 2 (FGF2), to tumor cells, and also increased expression of the heparan sulfate proteoglycan glypican 3 (GPC3), which plays an important role in cell division and growth. These findings were confirmed in mouse models. This discovery indicates if sc...
Glypican in Medical Technology

BioMosaics' Glypican-3 Blood & Tissue Tests Receive CE Marking in Europe

...ne 1G12) to detect GPC3 in tissue by immunohistochemistry (IHC), to be marketed in the European Union. GPC3, an oncofetal antigen, is a member of the glypican family of glycosyl phosphatidylinositol-anchored cell-surface heparan sulfate proteoglycans. The anti-GPC3 monoclonal antibody (MAb; clone 1G12) has a...
Glypican in Biological News

Glypican-3 gene function in regulating body size helps inform novel cancer treatments

...ncer Research in which cancer patients are being treated using Hedgehog-inhibitor drugs show promise. GPC3 or glypican-3 is one of six genes of the glypican family. Glypicans are expressed predominantly during development in a stage and tissue specific manner suggesting they play a role in cell growth and...
Glypican in Biological Products

Goat Anti-Human Glypican 2 Polyclonal Antibody, Biotin Conjugated from R&D Systems

Description: Human Glypican 2 Biotinylated Affinity Purified PAb...
Company:R&D Systems
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