Recent breakthroughs in common adult leukemia highlighted in New England Journal of Medicine
When the most common adult leukemia in the United States was last reviewed by the New England Journal of Medicine (NEJM) in 1995, it was seen through the eyes of theories that dated back to the 1960s. As such, the journal recently invited three of the world's foremost experts on chronic lymphocytic leukemia (CLL) to write an authoritative update covering the transformation in the scientific commu...Leukemia Drug Breakthrough Study In New England Journal Of Medicine
Alan List, M.D., leader of the Hematologic Malignancies Program at the H. Lee Moffitt Cancer Center & Research Institute, recently conducted a phase I/II trial of the experimental drug Revlimid showing promise as an innovative way to treat patients with myelodysplastic syndrome (MDS), a form of pre-leukemia. Given in pill form, Revlimid simultaneously blocks the growth of new blood vessels th...Researchers find gland that tells fruit flies when to stop growing
Many baffled parents have wondered whether their teenagers would ever stop growing. The answer is obvious, but researchers have never really quite understood just how an organism determines when it has reached its optimal size and growth should cease. Now University of Washington biologists studying the physiology of Drosophila melanogaster, the common fruit fly, have discovered an organ t...Scientists discover basic defect in cystic fibrosis airway glands
Scientists at Stanford University have determined that the buildup of sticky mucus found in cystic fibrosis is caused by a loss in the epithelial cell's ability to secrete fluid. This research appears as the "Paper of the Week" in the March 17 issue of the Journal of Biological Chemistry, an American Society for Biochemistry and Molecular Biology journal. Cystic fibrosis is the most commo...Study fishes out new role for prostaglandins
Prostaglandins ?the fat-derived compounds linked to pain, inflammation, reproduction and cancer ?can add another biological function to their extensive catalog. A new study by Vanderbilt researchers reveals that prostaglandins help choreograph the intricate cell movements during early embryonic development in zebrafish, highlighting how perturbations in this pathway might influence human d...15(S)-15-methyl Prostaglandin F2alpha from Cayman Chemical
Description:15(S)-15-methyl PGF2α is a metabolically stable analog of PGF2α. It is a potent uterine stimulant and abortifacient which can be administered intramuscularly to induce labor. It induces luteolysis and reduces serum progesterone concentrations when given as an intramuscular injection in non-pregnant rhesus monkeys....Hoagland's No. 2 Basal Salt Mixture from Sigma-Aldrich
Description:Formula variant: With the macro- and micronutrients as described by Hoagland and Arnon (1938). Suitab tst: plant cell culture tested...Ph.D. Peptide Display Cloning System from New England Biolabs
Description:The Ph.D. Peptide Display Cloning System facilitates the display of custom peptide libraries on the surface of bacteriophage M13 as coat protein fusions, creating a physical linkage between each displayed peptide and its encoding DNA sequence. Peptide ligands for a variety of targets can then be selected by the straightforward method of biopanning. The supplied display vector M13KE is an M13 deri...15(R)-17-phenyl trinor Prostaglandin F2alpha isopropyl ester from Cayman Chemical
Description:15(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester (15(R)-17-phenyl trinor PGF2α isopropyl ester) is the latanoprost-related isomer containing both a double bond at 13,14 and an inverted (β) hydroxyl group at C-15. Similar to 15(S)-latanoprost, 15(R)-17-phenyl trinor PGF2α isopropyl ester is a potential impurity in most commercial preparations of the latanoprost...IMPACT-CN System from New England Biolabs
Description:IMPACT (Intein Mediated Purification with an Affinity Chitin-binding Tag) utilizes the inducible self-cleavage activity of engineered protein splicing elements (termed inteins) to purify recombinant proteins by a single affinity column (1-4) (Figures 1 and 2). This system distinguishes itself from other protein fusion systems by its ability to separate a recombinant protein from the affinity tag...GE Healthcare wins $200m slice of Englands digital health-care plan
Englands National Health Service wants to install systems nationwide to allow medical images to be transmitted among hospitals so that experts can lo...What Will Primary Care Look Like In England by 2015?
The forthcoming white paper on health and community services in England will radically affect all our futures; so the BMJ asked people with an interest in general practice to predict the future//. Senior doctors at the Royal College of General Practitioners predict that general practices will be highly evolved strategic organizations collaborating with one another in a community network...Arsenic May Have Been Responsible For The Madness Of King George III Of England
An interesting study from hair of King George III reveals that he may// have been consuming Arsenic and this lead to his unusually severe and prolonged bouts of madness. Lancet has published this report this week and at last has been able to throw light on the reason for the madness of the famous English King George III. The study reports to have found high concentrations of arsenic...Indian Surgeon Conducts 70 Surgeries During His Holidays In England
A doctor with dedication and diligence in Britain of Indian origin hit headlines after conducting 70 //operations during his holiday period. NHS in the UK is well known for its long waiting lists and sometimes patients have to wait for years before getting a routine operation. This has brought NHS under criticism. Satya Agarwal of the Worthing and Southlands Hospital in Sussex h...Illegal Drug Use In England Mounting Up At An Alarming Rate
The trend towards illicit use of drugs is on the rise in England, accounting for more than 1 million visits and 400,000 admissions to the emergency department each year. The findings are based on anonymous interviews with // patients visiting the emergency department of a hospital in South West England. The doctor in charge of emergency care was also asked to assess the need for treat...Brain Injury, A Consequence Of Glandular Fever Could Trigger Fatigue Syndrome
Australian scientists from University of New South Wales have discovered that temporary injury to the brain during early inflammatory stages of glandular fever// could lead to chronic fatigue syndrome (CFS). More specifically, it might be related to specific regions of the brain that play a critical role in the perception pain and fatigue. An acute glandular fever infection could da...Research on New Treatment for Neglected Disease Published in The New England Journal of Medicine
SAN FRANCISCO & NEW DELHI, India--(BUSINESS WIRE)--Jun 21, 2007- The Institute for OneWorld Health, a US-based non-profitpharmaceutical company, today announced that Phase 3 researchrelated to its first approved drug product, Paromomycin IMInjection (Paromomycin), was published in the current issue of TheNew England Journal of Medicine (NEJM). This clinical trial showsthat the medicine...New England Journal of Medicine Publishes New Data on Gardasil, Merck's Cervical Cancer Vaccine
WHITEHOUSE STATION, N.J.--(BUSINESS WIRE)-May 10, 2007--Today, theNew England Journal of Medicine is publishing results from twoPhase III studies of Merck's cervical cancer vaccine, Gardasil(Quadrivalent Human Papillomavirus (Types 6, 11, 16, 18)Recombinant Vaccine). In the first study, Gardasil provided 100percent protection against cervical, vaginal and vulvar diseasescaused by the four H...