Alzheimer's-linked apolipoprotein E produced by neurons, Gladstone study
Scientists at the Gladstone Institute of Neurological Disease have now proved using a specialized mouse model that the controversial protein, apolipoprotein E, is indeed produced by neurons.// The results of this study have for the first time established a definitive association between the two. ...iPierian Appoints Dr. Chad Cowan and Dr. Konrad Hochedlinger to Scientific Advisory Board
...y (SMA), amyotrophic lateral sclerosis (ALS) and Parkinson's disease as well as in cardiovascular disease, where iPierian has a collaboration with The gladstone Institute of Cardiovascular Disease and Dr. Deepak Srivastava, the institute's director. iPierian plans to enhance its partnership efforts to further...Study in Nature: MicroRNAs hold promise for treating diseases in blood vessels
...t of both atherosclerosis and Alzheimer's disease, according to an article published online today in the journal Nature . The study was led by the gladstone Institute of Cardiovascular Disease (GICD) in San Francisco, with key contributions from the Aab Cardiovascular Research Institute at the University o...Building Healthcare Leadership in Africa: A Call to Action
...t Darkoh, Chairman, BroadReach Healthcare, LLC Dr. Warner Greene, President, Accordia Global Health Foundation, and Director and Senior Investigator, gladstone Institute Ms. Carol Spahn, Executive Director, Accordia Global Health Foundation Ms. Kelly Willis, Senior Vice President, Program Development, Accor...Calling All Motorcyclists: 'Da' U.P. Ride For The Red' to Benefit Red Cross
... Scenic ride and summer weekend fun ahead in gladstone GLADSTONE, Mich., April 21 /PRNewswire/ -- ... summer weekend of fun, food, and entertainment in gladstone with the first annual "Da' U.P. Ride for the Red" ... pancake breakfast at the Sports Park, sold by the gladstone Boy Scouts Troop 466. After breakfast, bikers will...UCSF symposium considers biomedical approaches to HIV/AIDS prevention
...ic is a high priority. This symposium will provide a timely overview of the most promising advances," said Warner C. Greene, MD, PhD, director of the gladstone Institute for Virology and Immunology (GIVI) and co-director of the UCSF-GIVI CFAR. Use of antiretrovirals for HIV prevention in uninfected individ...Collagen VI may help protect the brain against Alzheimer's disease
... SAN FRANCISCO, CA January 5, 2008 Scientists from the gladstone Institute of Neurological Disease (GIND), UCSF, and Stanford have discovere...an condition and to define its role in the disease," said Dr. Mucke. The gladstone team had profiled changes in gene expression using DNA microarrays, which p...Gladstone scientists identify role of fatty acids in Alzheimer's disease
... Scientists at the gladstone Institute of Neurological Disease (GIND) and the University of California have found that complete or partial removal of an enzyme that regulates fatt...September is National Pain Awareness Month
...23 years and nothing I was using was helping to stop it," said Campbell. After finally being treated with PRIALT, on the advice of her physician, Dr. gladstone McDowell at Grant Medical Center at OhioHealth in Columbus, Ohio, Campbell is now living with less pain than before. Though it took time to find the c...Gladstone investigators discover how resting T cells avoid HIV infection
Scientists have discovered the mechanism that enables some CD4 T cells -- the main target of HIV -- to thwart the virus. The discovery, reported on April 13 in the online version of Nature, could open the door to an entirely new strategy for preventing the spread of HIV infection in the body's cell...Gladstone scientists identify key factors in heart cell creation
... Scientists at the gladstone Institute of Cardiovascular Disease have identified for the first time key genetic factors that drive the process of generating new heart cells. The d...Gladstone scientists reveal key enzyme in fat absorption
... Scientists at the gladstone Institutes of Cardiovascular Disease (GICD) have found that a key enzyme involved in absorbing fat may also be a key to reducing it. The enzyme, acyl ...Gladstone scientists reveal that fat synthesizing enzyme is key to healthy skin and hair
... Scientists at the gladstone Institutes of Cardiovascular Disease (GICD) have found that an enzyme assoc...eptin, and have abnormalities in mammary gland development and skin. When gladstone researchers in the laboratory of Robert V. Farese, Jr. used genetic enginee...Yamanaka eliminates viral vector in stem cell reprogramming
... Shinya Yamanaka MD, PhD, of Kyoto University and the gladstone Institute of Cardiovascular Disease (GICD) has taken another step forward in improving the possibilities for the practical application of induced plur...Gladstone scientists create Wikipathways to foster research collaboration
...is prompting some scientists to focus on new ways to better manage that data and to make it readily available. The laboratory of Bruce Conklin in the gladstone Institute of Cardiovascular Disease has created a new collaboration tool, WikiPathways to focus on the use of biological pathways. "Biological ...Gladstone and Izumi Bio in partnership in regenerative medicine and cardiovascular disease
...June 16, 2008 --- iZumi Bio, Inc. and The J. David gladstone Institutes, an independent non-profit biomedical r...specific manner to avoid immune rejection. "The gladstone relationship with iZumi Bio combines our work in c... team," said Deepak Srivastava, MD Director of the gladstone Institute of Cardiovascular Disease. "It's an idea...Gladstone's Shinya Yamanaka wins prestigious Shaw Prize
... SAN FRANCISCO, CA June 11, 2008 The J. David gladstone Institutes today announced that senior investigator Shinya Yamanaka, MD, Ph...ch and the development of this technology for regenerative therapies," said gladstone president Robert W. Mahley, MD, PhD. "We're proud that our colleague has re...Embryonic stem cell strategy advanced with UCSF finding
...and diabetes. The reprogramming strategy pioneered by Yamanaka -- who in August began his transition from Kyoto University to the UCSF-affiliated gladstone Institute of Cardiovascular Disease and UCSF -- involved over-activating four genes in mouse skin cells in the culture dish. His team showed that over...Gladstone investigators identify a new protective action for the powerful anti-HIV factor, APOBEC3G
... Scientists at the gladstone Institute of Virology and Immunology (GIVI) have identified a previously un...he large A3G complex against select mobile genetic elements," Greene said. gladstone scientists are now exploring various ways to achieve this desired balance. ...iZumi Bio and Pierian Merge to Form iPierian to Advance Cellular Reprogramming
...gether with Dr. Deepak Srivastava, director of the gladstone Institute of Cardiovascular Disease and professor ...collaborations that have been established with the gladstone Institutes and Kyoto University's Center for iPS... Dr. Deepak Srivastava is the director of the gladstone Institute of Cardiovascular Disease, a professor o...iZumi Bio Appoints Dr. Corey Goodman to Board of Directors and Scientific Advisory Board
...cells. iZumi was founded in 2007 and is backed by Kleiner Perkins Caufield and Byers and Highland Capital Partners. iZumi has a collaboration with The gladstone Institute of Cardiovascular Disease and Deepak Srivastava, M.D., in the area of cardiovascular disease to identify potential targets that address unme...Gladstone scientists identify role of tiny RNAs in controlling stem cell fate
... SAN FRANCISCO, CA March 6, 2008--Researchers at the gladstone Institute of Cardiovascular Disease (GICD) and the University of California...l miRNAs in ES cell differentiation had not previously been determined. The gladstone team showed that miRNAs can control how pluripotent stem cells determine th...Hsiao Dee Lieu, M.D., F.A.C.C. Named VP of Clinical Research of Nile Therapeutics
...ment program for regadenoson, which included two large multinational successful Phase III trials. Dr. Lieu also worked as a researcher at the J. David gladstone Institute of Cardiovascular Disease at the University of California at San Francisco (UCSF) conducting molecular cardiology research in gene manipulat...Shinya Yamanaka reprograms human adult cells
...ough, reported in the journal Cell, should accelerate the pace of stem cell research. Last year, Yamanaka, who is also a senior investigator at the gladstone Institute of Cardiovascular Disease (GICD), reported that he and his Kyoto colleagues had reprogrammed mouse skin cells into pluripotent stem cells, l...Gladstone scientists uncover potential mechanism of memory loss in Alzheimer's disease
...SCO, CA -- September 6, 2007 -- Researchers at the gladstone Institute of Neurological Disease (GIND) and Baylo...sease. In a study published in the journal Neuron, gladstone scientists found that A-beta triggers abnormal ove...neration of nerve cells," said Jorge J Palop, PhD, gladstone research scientist and lead author of the study. "...