Mosaic mouse technique offers a powerful new tool to study diseases and genetics
A powerful laboratory technique used by fruit fly geneticists for more than a decade is now available to scientists studying genes and diseases in mice. Writing in the May 6 edition of the journal Cell, researchers from Stanford University describe a streamlined method for creating a "genetic mosaic mouse"--a rodent whose body is genetically engineered to produce small clusters of cells w...Genetics links whale to two different ocean basins
For the first time ever, a genetic study has followed a single humpback whale from one ocean basin to another, adding to traditional notions of the migratory patterns of these majestic marine mammals in the process, according to researchers from the Wildlife Conservation Society (WCS), the American Museum of Natural History (AMNH), and New York University. In the most recent Royal Society's Biolo...New technique could alter field of mouse genetics
Howard Hughes Medical Institute researchers have harnessed a mobile gene from the cabbage looper moth and modified it for routine use in mice and other vertebrates. If the new tool works as they expect, it will speed understanding of genes involved in human biology and disease and accelerate the search for effective new therapies. The researchers report their study in the August 12, 2005,...Scientists unpick genetics of first 15 minutes of life
Scientists have identified the gene responsible for controlling a first key step in the creation of new life, according to new research published in the journal Nature tomorrow (Thursday 27 October 2005). The gene, known as HIRA, 'chaperones' the early processes that take place once a sperm enters an egg, giving it a crucial role in the most fundamental process in sexually reproducing anim...New research examines genetics of successful aging
A study released today at the American College of Neuropsychopharmacology's Annual Meeting revealed that scientists have identified genes related to reaching age 90 with preserved cognition. The study, which was funded by the National Institutes of Health and conducted at the University of Pittsburgh, is among the first to identify genetic links to cognitive longevity. "While successful...LNA-ISH Cytogenetics - Human centromere alpha satelliteISH probes from Exiqon
Description:Exiqons LNA technology enables sensitive, fast and specific detection of chromosomal sequences directly on intact chromosomes. Related Conte...Mutation Surveyor from SoftGenetics, LLC.
Description:Researchers no longer need to perform time consuming and inaccurate comparison of the entire sample trace. With Mutation Surveyor, any found variants of the sample when compared to the wild type are clearly indicated in our mutation electropherogram as a sharp peak. Accuracy of the software in the bi-directional analysis mode is over 99%, with sensitivity to greater than 5% of the primary peak....GeneMarker from SoftGenetics, LLC.
Description:GeneMarker software has been designed and created in order to provide genetic researchers with a biologist friendly genotyping analysis tool. We incorporated the suggestions and requirements of several research groups into the software. Their main requirements were ease- of- use, high accuracy, flexibility and low acquisition cost. GeneMarker can perform analysis on up to 1,000 lanes of four or...Mutation Explorer from SoftGenetics, LLC.
Description:Mutation Explorer processes up to 48 lanes, 24 bi-directional, of patient DNA sequence traces. Data input can be from either slab gel or capillary sequencers, using either terminator or primer chemistries. The detection parameters in Explorer have been sealed to provide analyst to analyst consistency. We have built Explorer for ease of use, and quick learning. Normal operation involves only two...Wisconsin court affirms damages in Innogenetics, Abbott patent case
Madison, Wis. - The The Madison-based court affirmed the damage award to , a biopharmaceutical company based in Gent, Belg...Third Wave licenses Innogenetics tech to settle lawsuit
The two companies' relationship goes back further. In Aril 2004 Third Wave forged a deal under which Innogenetics was an exclusive distributor...Symposium examines the effect of race on genetics and disease
MADISON Health statistics are often broken down into categories by race. But increasingly, scientists question whether race is a meaningless concept that has no basis in biology or genetics. This was the concern of 40 scientists and ethicists at a symposium titled Race, Genetics & Disease at Grainger Hall April 16 and 17. The University of Wisconsin-Madisons <a href="http://www.sts.wisc...Genetics and cholesterol levels
According to a twin study reveals that cholesterol levels are controlled by both genes and dietary factors. People with high blood cholesterol are often advised to go on a low-fat diet - or to take cholesterol-lowering drugs. It's known that reducing fat intake can reduce cholesterol levels. But there is also a genetic condition called familial hypercholesterolaemia (FH) which leads to high chole...Genetics helps in attacking cancer
According to a new study, a trial of a new anti-cancer drug interacts with specific genes, which may help refine future treatments. Ceflatonin, a natural product, is being tested as an anti-cancer treatment. Meanwhile, the US company ChemGenex is looking at the effect of the drug on the genes that are activated in cancer. They find that specific genes and cellular pathways are affected by ceflat...Alcoholism Influenced By Both Genetics & Family Environment
In a study involving identical and non-identical twins, researchers conducted telephone interviews with 1,213 sets of male-male twins, average age 50.// The researchers’ goal was to better understand the hereditary and environmental effects on developing alcoholism -- not by studying the twins themselves, but by interviewing the twins’ children (ages 12 to 26) and the mothers of those children. <...Genetics linked to leukemia treatment success rate in children
Genes may be at the root of how children react to cancer treatments.// A new study by the researchers funded by American Society of Hematology says that personalized medicine based on the genetic makeup of children may yield better results in treating childhood leukemia. Researchers had looked into the records of 246 children suffering from acute lymphoblastic leukemia (ALL). The patie...Genetics Has A Major Role To Play In Body Shape.
Scientists in a major breakthrough in the study of treating obesity have identified a gene FOX gene,// which is associated with gain in weight. This now explains why people despite not eating too much tend to put on weight and turn obese. The logical sequence for obesity is input of food being greater than the energy expenditure, but in certain situations this is not the case....Cytogenetics, High Resolution & Fragile X DNA
Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...Genetics Journal Thimerosal/Autism Study the 'Best Science Drug Company Money Can Buy'
Critique of Industry-Funded Immune Globulin Study Uncovers SampleManipulation, Design Flaws NIXA, Mo., June 26, 2007 /PRNewswire-USNewswire/ -- An analysisreleased today critically examined a recent industry-sponsoredstudy ruling out a link between autism and Rh immune globulin(RhIg) injections, some of which contained the mercury-basedpreservative thimerosal. Besides extensive design fla...Targeted Genetics Reports Inflammatory Arthritis Clinical Data at European Rheumatology Conference
BARCELONA, SPAIN and SEATTLE, WA -- (MARKET WIRE) -- June 14,2007 -- Targeted Genetics Corporation (NASDAQ: TGEN) today isreporting data from the dose escalation arm of the ongoing PhaseI/II clinical study of tgAAC94 in patients with inflammatoryarthritis. Philip J. Mease, M.D., clinical professor at theUniversity of Washington School of Medicine, chief of rheumatologyclinical research a...