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gene in Medical News

Covance to Acquire Seattle-Based Gene Expression Laboratory from Merck & Co., Inc.

PRINCETON, N.J., July 29 /PRNewswire-FirstCall/ -- Covance (NYSE: CVD ) today announced it has entered into a definitive agreement with Merck & Co., Inc. relating to the supply of genomic analysis services. Under the terms of the agreement Merck has committed to ...

Developing gene therapy to fight blindness

An international team of scientists and clinicians from the United States and Saudi Arabia are working to develop gene therapy for treating a rare, hereditary retinal disease. The therapy has been shown to restore lost vision in animal models of retinitis pigmentosa (RP). Their work is being fun...

Bcl6 gene sculpts helper T cell to boost antibody production

HOUSTON - Expression of a single gene programs an immune system helper T cell that fuels rapid growth and diversification of antibodies in a cellular structure implicated in autoimmune diseases and development of B cell lymphoma, scientists at The University of Texas M. D. Anderson Cancer Center r...

Immune System Gene Discovery Sheds Light on Staph Infections

Findings could lead to better therapies for severe forms of the disease TUESDAY, July 21 (HealthDay News) -- Researchers at the University of Texas Southwestern Medical Center have figured what genes turn on and off in a person's immune system when he or she has a severe staph infectio...

New Gene May Signal Aggressive Breast Cancer

Finding provides insight into tumor growth, metastasis, researchers say MONDAY, July 20 (HealthDay News) -- Scientists have identified a new gene that may contribute to aggressive breast cancer, new research shows. Using a new method of analyzing "microarray expression profiles" of ...

Catastrophic Epilepsy Caused by Defect in One Gene

Mouse study led to discovery of mutation and could advance treatments WEDNESDAY, July 8 (HealthDay News) -- A mutation in a single gene causes catastrophic epilepsy, U.S. scientists say. And that finding, they say, could lead to treatments or a cure for the disorder. People with cat...

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gene in Medical Technology

Diabetes Gene Raises Odds of Lower Birth Weight

PHILADELPHIA, July 29 /PRNewswire-USNewswire/ -- Pediatric researchers have found that a gene previously shown to be involved in the development of type 2 diabetes also predisposes children to having a lower birth weight. The finding sheds light on a possible genetic influence on ...

Bionovo's Estrogen Receptor Beta Selective Drugs Have Unique Gene Expression and Cell Type Specificity

EMERYVILLE, Calif., July 17 /PRNewswire-FirstCall/ -- Bionovo, Inc. (Nasdaq: BNVI ) announced today that a study of the gene regulation in multiple cell lines by several of their estrogen receptor beta (ERb) candidates will be published in Public Library of Science One. ...

More Gene Mutations Linked to Autism Risk

--Combination of Inherited and New Genetic Mutations Acting Together-- PHILADELPHIA, June 26 /PRNewswire-USNewswire/ -- More pieces in the complex autism inheritance puzzle are emerging in the latest study from a research team including geneticists from The Children's Hospital of Philadelphia...

Genomic Health Study Shows Breast Cancers in Men Display Very Similar Gene Signatures to Those in Women

- Largest Genomic Study Comparing Gene Expression in Female and Male Patients Presented at ASCO Annual Meeting - ORLANDO, Fla., May 29 /PRNewswire-FirstCall/ -- Genomic Health, Inc. (Nasdaq: GHDX ) today announced results from a study which summarized the gene signatures identified by the O...

Celladon Provides MYDICAR(R) Program Update of First-In-Human Trial for Advanced Heart Failure at American Society of Gene Therapy Annual Meeting

Phase 1 Data Demonstrate Safety and Evidence of Biological Activity in 9 of 12 Patients; Phase 2 Study Currently Enrolling in 17 Leading U.S. Medical Centers SAN DIEGO, May 28 /PRNewswire/ -- Celladon Corporation presented today Phase 1 data from the Calcium Up-Regulation by Percutaneou...

In Rare Disorder, a Familiar Protein Disrupts Gene Function

-Knowledge May Improve Diagnosis for Children with Cornelia deLange Syndrome- PHILADELPHIA, May 27 /PRNewswire-USNewswire/ -- An international team of scientists studying a rare genetic disease discovered that a bundle of proteins with the long-established function of keeping chromo...

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gene in Medical Products

Prothrombin Nucleotide 20210 G/A Gene Mutation (Factor II), Fetal

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Prothrombin Nucleotide 20210 G/A Gene Mutation (Factor II)

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

mecA Gene by PCR

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Ig Heavy Chain Gene Rearrangement, Tissue

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Ig Heavy Chain Gene Rearrangement, Paraffin

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Ig Heavy Chain Gene Rearrangement, Fluid

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

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gene in Medical Definition

Atransferrinemia

...is inherited in an autosomal recessive pattern, meaning two copies of the gene in each cell are altered. A case study was done in 1961 on a 7-ye...reported in the United States [2] and identified mutations in the TF gene as a probable cause of the disorder. Treatment Treatment with i...

Autoimmune regulator

...1 q22.3 The Autoimmune Regulator, abbreviated AIRE , is a human gene which is expressed in the thymus . It causes transcription of a wide sel...taneous candidiasis. [1] AIRE is expressed primarily in the thymus. A gene knockout of the murine homolog Aire has created a transgenic mouse mode...

Familial isolated vitamin e deficiency

...ciency is a rare autosomal recessive neurodegenerative disease. Symptoms are much like those of Friedreich ataxia and is caused by mutations in the gene for a-tocopherol transfer protein. ...

Medical procedure

...onvulsive therapy Symptomatic treatment Fluid replacement therapy Palliative care Hyperbaric oxygen therapy Oxygen therapy gene therapy Enzyme replacement therapy Intravenous therapy Kinesiotherapy Phage therapy Serotherapy Respiratory therapy Vision ...

Pathology

...tic process in a tissue, and is marked by persistance of immature, poorly differentiated cell forms. Interestingly, there are many similarities in the gene pathways activated in cancer cells, and those activated in cells involved in wound healing and inflammation. [8] Pathology as a medical sp...

Medicine

...idence-based medicine . Many modern molecular tests such as flow cytometry, polymerase chain reaction (PCR), immunohistochemistry , cytogenetics , gene rearragements studies and fluorescent in situ hybridization (FISH) fall within the territory of pathology. Radiology is concerned with ima...
gene in Medical Dictionary

Gene

The main homepage for Human Genome Project information --what the project is; its progress, history, and goals; what issues ... Gene Gateway. Research Archive ... The analysis of gene sets has become a popular topic in recent times, with ... While a number of options for gene set analysis...

Xeroderma Pigmentosum

...eroderma Pigmentosum : symptoms, cause, treatments, complications, prevention, risks ... People with xeroderma pigmentosum have a defect in the gene that is ... A US Department of Health and Human Service project providing information on genetic and rare diseases. A comprehensive body of res...

Wilson disease

...c disease that leads to copper ... Bull PC et al. The Wilson disease gene is a putative copper transporting P-type ... Wilson's Disease info...information on Wilson's Disease . ... If both parents carry an abnormal gene for Wilson's disease there is a: ... Wilson's disease &mda...

Von Hippel-lindau Disease

... Lindau syndrome, is a rare ... At present, this gene is the only gene known to cause von Hippel - Lindau disease ..... The von Hippel - Lindau disease (VHL) gene is a putative tumor suppressor ...

Von Hippel-Lindau

...ndrome, is a rare ... The von Hippel - Lindau gene is located on the short arm of chromosome 3 (3p...tumor suppressor protein is encoded by the VHL gene and ... The von Hippel - Lindau Tumor Suppressor gene and Kidney Cancer" ... Article describes von ...

Vesicle

...in all species, ... GO:0030659 : cytoplasmic vesicle membrane [391 gene products] ... GO:0030120 : vesicle coat [200 ... GO:0030136 : clathrin-coated vesicle [441 gene products] ... vesicle -associated membrane protein synaptobrevin ...

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gene in Biological News

Methods for gene transfer in stem cells featured in Cold Spring Harbor Protocols

COLD SPRING HARBOR, N.Y. (Wed., Aug. 5, 2009) Vectors derived from retroviruses are useful tools for long-term gene transfer because they allow stable integration of transgenes and propagation into daughter cells. Lentiviral vectors are preferred because they can transduce non-proliferating ce...

Cancer's distinctive pattern of gene expression could aid early screening and prevention

AUGUSTA, Ga. Distinctive patterns of genes turned off or left on in healthy versus cancerous cells could enable early screening for many common cancers and maybe help avoid them, Medical College of Georgia scientists say. Researchers are comparing chemical alterations, called DNA methylatio...

Newly discovered gene fusion may lead to improved prostate cancer diagnosis

Researchers from NewYork-Presbyterian Hospital/Weill Cornell Medical Center have discovered a new gene fusion that is highly expressed in a subset of prostate cancers. The results may lead to more accurate prostate cancer testing and new targets for potential treatments. Experts believe that gene ...

Scientists discover gene mutation responsible for hereditary neuroendocrine tumor

SALT LAKE CITY University of Utah researchers and their colleagues have identified the gene that is mutated in a hereditary form of a rare neuroendocrine tumor called paraganglioma (PGL). The gene, called hSDH5, is required for activation of an enzyme complex that plays a critical role in the che...

Reviews of microbial gene language published in special issue of Trends in Microbiology

Blacksburg, Va. -- Ten articles describing how a universal language to describe genes is bringing benefits to the study of the microbial world have been published in a special issue of Trends in Microbiology , co-edited by Virginia Bioinformatics Institute professor Brett Tyler. The Gene Ontology...

Further gene mutations linked to autism risk

Pieces in the complex autism inheritance puzzle are emerging in the latest study from a research team including geneticists from the University of Pennsylvania School of Medicine and The Children's Hospital of Philadelphia (CHOP). The study identified 27 different genetic regions where rare copy n...

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gene in Biological Technology

Cardium Announces New Orthobiologics Product Initiative Extending Gene Activated Matrix Technology to Deliver Bone Growth Factors

SAN DIEGO, July 30 /PRNewswire-FirstCall/ -- Cardium Therapeutics (NYSE Amex: CXM ) today announced plans to develop a DNA-based orthobiologics product portfolio based on research and development by Cardium's Tissue Repair Company that will initially focus on non-union bone fractu...

United States FDA Clears the REGEN Trial to Test Bioheart's Combination Gene and Stem Cell Therapy in Heart Failure Patients

SUNRISE, Fla., July 28 /PRNewswire-FirstCall/ -- Bioheart, Inc., (OTC Bulletin Board: BHRT) a company committed to delivering intelligent devices and biologics that help monitor, diagnose and treat heart failure and cardiovascular diseases announced today that the US FDA cleared a p...

Canadian researchers discover gene related to the appearance of aging

HALIFAX, July 15 /PRNewswire/ - Scientists in Atlantic Canada have found a gene that may play a role in skin aging. Researchers were investigating the genetic cause of a rare disorder known as cutis laxa type 2 (CL2), which causes skin on the hands, feet and face to be loose and older looking, as ...

Novel gene found for dilated cardiomyopathy

Researchers in the Heart Institute at Cincinnati Children's Hospital Medical Center have discovered a novel gene responsible for heart muscle disease and chronic heart failure in some children and adults with dilated cardiomyopathy (DCM). Mutations in the ANKRD1 gene may cause DCM, which is the...

deCODE Discovers a Gene Linked to Risk of Kidney Stones and Osteoporosis

REYKJAVIK, Iceland, June 29 /PRNewswire-FirstCall/ -- A discovery by scientists at deCODE genetics (Nasdaq: DCGN ) and academic colleagues from Iceland, the Netherlands and Denmark has pointed to a common biological mechanism contributing to both kidney stones and decreased bone mineral densi...

Syngenta Licenses Chromatin Gene Stacking Technology for Sugar Cane

RESEARCH TRIANGLE PARK, N.C., June 26 /PRNewswire/ -- Syngenta Biotechnology, Inc. announced today that it has entered into an exclusive worldwide research and commercial license agreement for Chromatin's proprietary gene stacking technology in sugar cane. Chromatin has developed a novel ap...

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gene in Biological Products

Chicken Anti-G4-1 (Hypothetical protein FLJ20644, likely ortholog of mouse phosphatase subunit gene g4-1) Polyclonal Antibody, Unconjugated from GenWay Biotech, Inc.

Description: G4-1, Affinity-Purified Polyclonal IgY Antibodies Hypothetical protein FLJ20644, likely ortholog of mouse phosphatase subunit gene g4-1 Protein Accession #: NP_060387.1 gi number query: 8923600 Genbank Definition: chromosome 14 open reading frame 10; likely ortholog of mouse phosphatase su...
Company:GenWay Biotech, Inc.

21-mer duplex design + syn.; 1 gene from B-Bridge International

Description: siSolutions siRNA Custom Synthesis Service provides you with high-quality, effective duplex RNA to knockdown any gene. We offer standard 21-mers (19 RNA base pairs with terminal dT nucleotides), the recently-published 27-mers, or other lengths of your choice. Each individual sequence includes quali...
Company:B-Bridge International

3x 21-mer duplex design + syn.; 1 gene from B-Bridge International

Description: siSolutions siRNA Custom Synthesis Service provides you with high-quality, effective duplex RNA to knockdown any gene. We offer standard 21-mers (19 RNA base pairs with terminal dT nucleotides), the recently-published 27-mers, or other lengths of your choice. Each individual sequence includes quali...
Company:B-Bridge International

Immunohistochemistry - Gene Discovery from Paragon BioServices

Description: This service involves the optimization of immunostaining. The optimization includes titration of the primary antibody, selection and optimization of secondary reagents (e.g. Alk. Phos., HRP, fluorescence, or biotinylated conjugates), optimization of detection, evaluation by light or fluorescence m...
Company:Paragon BioServices

CopyControl cDNA, Gene and PCR Cloning Kit w/ Chemically Competent E. coli cells from EPICENTRE Biotechnologies

Description: The CopyControl™ PCR Cloning Kits are designed to speed up the PCR cloning process and to ensure that all PCR products, regardless of sequence or type of polymerase used, are efficiently cloned. All PCR products including those that are difficult to clone by other PCR cloning methods or that m...
Company:EPICENTRE Biotechnologies

steadylite plus Reporter Gene Assay System, 1000 mL from PerkinElmer

Description: The steadylite plus assay system offers the following benefits: High assay sensitivity, Designed for batch-processing systems, Long lasting signal, Suitable for higher density microplates such as 384-well and 1536-well plates, Odor free, Convenient storage conditions ( 2 - 8 C)...
Company:PerkinElmer

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gene in Biological Definition

Gene

Genes are entities that parents pass to offspring during reproduction . These entities encode information essential for the construction and regulation of polypeptides , proteins and other molecules that determine the growth and functioning of the organism . The word "g...

Albinism

...xternal links Lack of pigmentation The gene which results in albinism prevents the body from m...aneous albinism, individuals inherit an "albinism gene " from both parents. Where an individual receives one albinism gene and one normal gene, that person will not show out...

Allele

... one of a number of alternative forms of the same gene occupying a given locus (position) on a chromosome . An example is the gene for blossom color in many species of flower - a single gene controls the color of the petals, but there may be...

Allele frequency

... population , or equivalently the richness of its gene pool . Allele frequency is defined as follows: Given a) a particular chromosome locus , b) a gene occupying that locus, c) a population of individu... The frequencies of all the alleles of a given gene often are graphed together as an allele frequency...

Alternative splicing

...to a modification of the definition of a "gene". Some have proposed that a gene should be considered as a twofold information structure: A DNA sequenc... of coding. Others have noted that it is unnecessary to change the DNA of a gene for the evolution of a new protein. Instead, a new way of regulation coul...

Antibody

...ntigens, it must produce millions of B lymphoyctes. It is important to note that to produce such a diversity of antigen binding sites with a separate gene for each possible antigen, the immune system would require many more genes than exist in the genome . Instead, as Susumu Tonegawa showed in 1976, ...

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gene in Biological Dictionary

Gene

A gene is the basic unit of heredity in a living organism. All living things depend on genes. Genes hold the information to build and maintain their cells and pass genetic traits to offspring. A modern working definition of a... Gene therapy is the insertion of genes into an individual...

Structural gene

A structural gene is a gene that codes for any RNA or protein product other than a regulatory factor . It may code for a structural protein, an enzyme, or an RNA molecule not involved in regulation. Aspects of the topic structural - gene are discussed in the following places at B...

Reporter Gene

In molecular biology, a reporter gene is a gene that researchers attach to another gene of interest in cell culture, animals or plants. Certain genes are chosen as reporters because the characteristics they confer on organisms expressing them are easily identified and... The GUS rep...

Recessive gene

In classical genetics, dominance describes a relationship between different forms (alleles) of a gene at a particular physical location (locus) on a chromosome. Typical plants and animals have two sets of chromosomes, one set inherited from each parent, and are... In genetics, dominance desc...

Expressed gene

Genes are expressed by being transcribed into RNA, and this transcript may then ... which a particular gene is expressed within a cell, tissue or organism can give ... ... the transcription machinery when a gene is about to be transcribed and expressed . ... of the n...

Dominant gene

In classical genetics, dominance describes a relationship between different forms (alleles) of a gene at a particular physical location (locus) on a chromosome. Typical plants and animals have two sets of chromosomes, one set inherited from each parent, and are... In genetics, dominance desc...

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