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Gastroparesis in Medical News

NPs-NPR-B/pGC-cGMP signal pathway is involved in diabetic gastroparesis

The natriuretic peptide (NP) receptor type B (NPR-B) gene was expressed in gastric smooth muscles of normal and diabetic rats and the expression was increased in diabetic rats. These results suggest that natriuretic peptide-dependent pGC-cGMP signal is up-regulated and it may contribute to diabeti...

Two Studies at AACE 2009 Annual Meeting Highlight Effects of Welchol(R) (colesevelam HCl) on Blood Glucose and LDL-C in Patients with Type 2 Diabetes

...l were memory impairment (n=1) and increased sweating (n=1). Serious adverse events, all unrelated to Welchol, were breast cancer (n=2), and diabetic gastroparesis and unilateral blindness (n=1). In total, 15 patients had serious adverse events, which were considered not related (n=13) or unlikely related (n=2) ...
Gastroparesis in Medical Technology

Tranzyme Pharma Presents Initial Phase IIa Data for its Novel Ghrelin Agonist, TZP-101, in Patients with Diabetic Gastroparesis

RESEARCH TRIANGLE PARK, N.C. & SHERBROOKE, Quebec--(BUSINESS WIRE)--Jun 26, 2007 - Tranzyme Pharma, a leading biopharmaceutical company developing small molecule drugs for the treatment of gastrointestinal and metabolic diseases, today announced positive results for its novel ghrelin agonist, T...

Mayo Clinic Discovery May Help Diabetic Gastric Problem

... issue of the journal Gastroenterology ( http://www.gastrojournal.org/ ). gastroparesis occurs when the stomach retains food for longer periods. When that food eve...ucose level -- critical for controlling diabetes -- also becomes difficult. gastroparesis can cause pain, nausea, vomiting, stomach spasms and weight loss due to ina...

Synvista Therapeutics' Alagebrium Shows Potential for use in Treating Diabetes-Related Gastrointestinal Complications

...nse investigation and thorough review(1). Diabetic gastroparesis is a motility disorder in which the stomach takes ...sricha is also Chairman of the NIH-funded Diabetic gastroparesis Consortium, which has a mandate to better characte...nal dysfunction, diabetic enteropathy and diabetic gastroparesis and the role that alagebrium may play in those dis...
Gastroparesis in Medical Products

Programmer System (Enterra™ Therapy)

Description:... indicated for the treatment of chronic nausea and vomiting associated with gastroparesis when conventional drug therapies are not providing adequate relief of sympt...tomach. This electrical stimulation may reduce the symptoms associated with gastroparesis including nausea and vomiting....
Company:Medtronic Gastroenterology

Medtronic ITREL 3 Model 7425G Neurostimulator (Enterra™ Therapy)

Description:... indicated for the treatment of chronic nausea and vomiting associated with gastroparesis when conventional drug therapies are not providing adequate relief of sympt...tomach. This electrical stimulation may reduce the symptoms associated with gastroparesis including nausea and vomiting....
Company:Medtronic Gastroenterology

Medtronic Model 4351 Lead (Enterra™ Therapy)

Description:... indicated for the treatment of chronic nausea and vomiting associated with gastroparesis when conventional drug therapies are not providing adequate relief of sympt...tomach. This electrical stimulation may reduce the symptoms associated with gastroparesis including nausea and vomiting....
Company:Medtronic Gastroenterology
Gastroparesis in Medical Definition

Pathology

...alasia - Esophageal cancer - Esophageal varices Stomach Peptic ulcer - Abdominal pain - Stomach cancer - Non-ulcer dyspepsia - gastroparesis - Abdominal angina - Malabsorption (e.g. celiac disease , giardiasis ) - Pyloric stenosis Small intestine Peptic ulcer - Intuss...
Gastroparesis in Medical Dictionary

Gastroparesis

Gastroparesis , also called delayed gastric emptying, is a medical condition consisting of a paresis of the stomach, resulting in food remaining in the stomach for a longer period of time than normal. Normally, the stomach contracts to move food down into the small... Gastroparesi...
Gastroparesis in Biological News

FDA Approves New Drug to Treat Type I and Type II Diabetes

...this risk is greatest in patients with type 1 diabetes and in patients with gastroparesis (motility problems of the stomach-a long-term complication of diabetes). Se...uld not be used if patients cannot tell when their blood sugar is low, have gastroparesis (slow stomach emptying), or are allergic to pramlintide acetate, metacresol...
Gastroparesis in Biological Technology

Evoke Pharma, Inc. Initiates Phase 2b Metoclopramide Intranasal Trial (MINT) in Patients With Diabetic Gastroparesis

SAN DIEGO, May 5 /PRNewswire/ -- - Evoke Pharma, Inc., a privately-held specialty pharmaceutical company, announced today that it has initiated a Phase 2b clinical trial to evaluate EVK-001 for the treatment of adults with symptoms of diabetic gastroparesis. Gastroparesis is a syndrome characteriz...
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