Tips from the journals of the American Society for Microbiology
...nology . Gastrin-releasing peptide (GRP) is an important human peptide that regulates gastric acid secretion and motor function as well as elicits gastrin release. Previous research has shown that GRP plays a significant role in human cancers through atypical expression of the GRP receptor and GRP bindi...Transition Therapeutics Announces Third Quarter Fiscal 2009 Financial Results
... enrolment for a Phase II clinical study of gastrin analogue, TT-223, in patients with type 2 ...e rights to develop and commercialize Transition's gastrin based therapies, including the lead compound TT-22...sales milestones, as well as royalties on sales of gastrin based therapies if any product is successfully com...Transition Therapeutics Announces Second Quarter Fiscal 2009 Financial Results
... enrolment for a Phase II clinical study of gastrin analogue, TT-223, in patients with type 2 ...diabetes animal models demonstrate the efficacy of gastrin analogues alone, or in combination with GLP-1 anal...ith TT-223 in combination with EGF (combination of gastrin analogue and epidermal growth factor analogue) in ...Transition Therapeutics Announces First Quarter Fiscal 2009 Financial Results
...first patient in a Phase II clinical study of gastrin analogue, TT-223, in patients with type 2 dia...ith TT-223 in combination with EGF (combination of gastrin analogue and epidermal growth factor analogue) in ...treatment. Pre-clinical and clinical data suggests gastrin plays an important role in beta cell differentiati...Transition Therapeutics Announces Second Quarter Fiscal 2008 Financial Results
... that 4-weeks of E1-I.N.T. therapy (combination of gastrin analogue and epidermal growth factor analogue) in ...treatment. Pre-clinical and clinical data suggests gastrin plays an important role in beta cell differentiati...tion has commenced the studies to advance its lead gastrin analogue, TT-223, formerly known as "G1", into Pha...Transition Therapeutics Announces Fiscal 2007 Year End Financial Results
...ths. These clinical data support the potential of gastrin as a therapeutic in combination with other diabete...ds the exclusive rights to a series of proprietary gastrin based combination therapies including GLP1-I.N.T.(TM) (a combination of gastrin analogue, G1, and a GLP-1 analogue) and combinatio...Gastrin, Much More Than The Weight Management Hormone
... It has been long contemplated that gastrin is responsible for controlling the urge to eat and...edical Branch at Galveston have linked the hormone gastrin to the body’s ability to maintain normal weight an... on mice, the UTMB researchers found that removing gastrin production triggered obesity, insulin resistance a...Lilly and Transition Therapeutics Announce Licensing and Collaboration Agreement
... Lilly to Acquire Exclusive Rights to gastrin Based Therapies Program for ...e rights to develop and commercialize Transition's gastrin based therapies, including the lead compound TT-22...opment activities and the commercialization of all gastrin based therapeutic products worldwide. Other terms ...Tummy troubles -- gastrin key in bacterial-induced stomach cancer
New York, New York Current research suggests that levels of gastrin play a key role in the development of Helicobacter -induced stomach cancer. The related report by Takaishi et al, "Gastrin is an essential cofactor for Helicobacter -associated gastric corpus carcinogenesis in C57BL/6 mice," a...