VIDEO from Medialink and Shire plc: Rare Diseases Must Be Top of the Health Agenda
...idneys, heart, and brain. The disease is caused by a genetic mutation that results in a lack of, or low level or activity of, an enzyme called alpha galactosidase A (a-Gal A). This enzyme is needed by the body to break down a fatty substance called globotriaosylceramide (Gb3). Without the enzyme this fatty subst...Identification Of Gene Sequence To Promote Growth Of New Arteries
...there was a decrease in the blood flow. The transgenic mice created, by David Lovett, provided a representation of the arterial blockage. The beta galactosidase gene marker was incorporated into the transgenic mice, which turns tissues blue. Different strains of the mice had different fragments of the MMP2 gen...Transient Gene Expression Following Single and Double Exponential Decay Electroporation Pulses
...ng to the manufacturers protocol, collecting the light produced by 20l of extract for 10 sec with an MGM Optocomp I luminometer. galactosidase was determined in the same cell extracts using the chemiluminescent Galacto-Light assay (Tropix, Cambridge, Massachusetts) in the same lumi...Immunodetection of Specific Proteins from QualTek Molecular Laboratories
Description:...Fluorescent, or Electron Microscopy Protein Localization in Transgenic Animals Hundreds of Specialty Markers, Including: Vector Detection with - galactosidase Proliferation Markers - PCNA, Brdu, Ki67 Neural and Glial Markers Apoptosis Related Proteins Visualization of Low Expresser Proteins...