Key Protein Might Shield Brain Cells
... with another protein when it attempts to latch onto a multifunctional molecule called glyceraldehyde-3-phosphate dehydrogenase (GAPDH). By binding to gapdh
itself, GOSPEL prevents the cell death cascade and protects brain cells against toxic compounds, according to the study.
The finding is published i...
Cells Re-Energize to Come Back From the Brink of Death
...apoptosis increases the levels of an enzyme called gapdh
in order to counteract the backup program called caspase-independent cell death (CICD). gapdh
appears to prevent CICD by supporting the function...
The findings also suggest that the increase in gapdh
provides energy to increase autophagy -- the proce...
Basis for Nerve fiber Damage in Multiple Sclerosis Discovered
...nd in spinal fluid bound to two specific enzymes – gapdh
These two enzymes are essential for ef...th. In addition to the energy-production function, gapdh
is involved with a number of genetic activities, s...t studies have shown that binding of inhibitors to gapdh
and TPI causes decreased ATP production in neurons...