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Futility in Medical News

South African policy on adolescents' rights to access condoms is causing confusion

...sive issue. Critics believe that making contraception available encourages sexual activity. But proponents cite the early age of sexual debut and the futility of HIV prevention education that encourages condom use but fails to actually provide condoms. The researchers' own work with Mpilonhle, in which th...

Clot Dissolver Doesn't Boost Survival in Cardiac Arrest Patients

...cardiac arrest "because of low survival," the report said. It was started again with a change in the treatment routine but "terminated prematurely for futility after enrolling a total of 1,050 patients." The 30-day survival rate was actually lower for people given tenecteplase: 14.7 percent versus 17 perce...

Annual medical ethics conference celebrates 20 years of disputes

...evine, Jack Wennberg, Peter Ubel* 4:30-5:30 pm futility and Hope Paper #5: "Pascal's Wager and the Hanging of Crepe." 1975 Paper #6: "The Illusion of futility in Clinical Practice." 1989. Paper #7: "The Rise and Fall of the futility Movement." 2000. Speakers: William May, John Lan...

Biopure Receives Comment Letter From U.K. Regulatory Body on Marketing Application for Hemopure(R)

...n has not advised the company to withdraw its application. The company has been advised that such a request would be the customary means of indicating futility or rejection of an application. "We intend to proceed by meeting and consulting with the UK regulatory review team, as suggested, as soon as possibl...

Genaera Discontinues Lomucin in Cystic Fibrosis Studies

...Genaera Corporation announced that, in conjunction with Cystic Fibrosis Foundation Therapeutics, Inc. (CFFT), both parties have agreed for reasons of futility to discontinue the Phase 2 study of LOMUCIN(TM) for the treatment of cystic fibrosis (CF). Genaera also announced that the Phase 2 study of squalamine...

Bali Bombings Helped Improve Trauma Care

...hysical pain than their injuries would be expected to cause, together with a physical ache over their losses, thoughts of what could have been and the futility of the situation. "All spoke in their own ways of how they felt their safety and personal space had been violated, Guscott added. The early ...

Black and White in ‘Shades of Grey

... biological and cultural evolution. As we dream of a global village and a world sans cross- country borders, it would indeed be apt to ponder on the futility of humans alienating each other on the basis of color and ethnicity. Did the barriers arise in the minds of men before they were transformed into geog...

Motivation Yardstick: Rewards or Punishment? Discover the Superior Performance Trigger

...tutions lacking mechanisms for punishing freeloaders." But Kairen Cullen, a group behavior expert from the University of London, emphasized the futility of negative psychology triggers in a group and said, “In a group you will always get a minority who do not work for the common good. But it is much mo...

Brain death – How to cope with it

... from medical staff. However by witnessing tests to confirm that the patient is actually brain dead, the family and friends can be convinced about the futility of prolonging the life support, say doctors. Two-thirds of consultants and nurses who had previous experience of relatives being present during tes...
Futility in Medical Technology

Neurobiological Technologies Announces Viprinex(TM) Does Not Pass Interim Futility Analysis

EMERYVILLE, Calif., Dec. 17 /PRNewswire-FirstCall/ -- Neurobiological Technologies, Inc. (NTI(R)) (Nasdaq: NTII ) today announced that an independent Data Safety Monitoring Board (DSMB) has determined that the current clinical trials of Viprinex(TM) for the treatment of acute ischemic stroke are...

Neurobiological Technologies Announces FDA Agreement to Consolidate Viprinex Phase 3 Trials Accelerating Time to Pivotal Data

...ted by an independent Data Safety Monitoring Board (DSMB) that will examine futility as well as safety. This constitutes a "go, no-go" decision point for the Viprinex clinical program. Passing the futility analysis would indicate that the drug has met predetermined interim efficac...

Avicena Announces Positive Phase II Data for a Combination Trial Involving AL-08 for the Treatment of Amyotrophic Lateral Sclerosis (ALS)

...y of two drug combinations, AL-08/ minocycline and AL-08/celecoxib. The trial used a group sequential design and a natural history control group for a futility analysis. The primary objective was treatment selection based on which drug combination appeared to slow deterioration in the ALS-Functional Score. ...
Futility in Biological Technology

AutoImmune Inc. Reports 2008 Third Quarter Financial Results

...t track designation by the FDA and that it had received a milestone payment from Eli Lilly for successfully passing an interim analysis for safety and futility in its pivotal phase II/III trial of MBP8208 for treatment of secondary progressive multiple sclerosis. We expect the final trial data will be availab...

Neurobiological Technologies, Inc. Reports First Quarter Fiscal Year 2009 Financial Results

...f 650 patients), the first 500 of which will be considered for the upcoming interim analysis, which we expect to complete by January 2009. The interim futility review will constitute a major go/no-go decision for the Viprinex program, since it is the first efficacy assessment ever by our independent Data Safe...

Biopure Announces MHRA Meeting Update

...n has not advised the company to withdraw its application. The Company has been advised that such a request would be the customary means of indicating futility or rejection of an application. Biopure submitted its application for the treatment of acutely anemic adult orthopedic surgery patients less than 80 y...
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