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Fumarate in Medical News

Concomitant treatment with nebulized formoterol fumarate & tio-significant improvements -- COPD

Napa, CA, (May 20, 2008) A newly published study presents data demonstrating that patients with Chronic Obstructive Pulmonary Disease (COPD), including emphysema and chronic bronchitis, experienced markedly improved bronchodilation and symptom control when treated with a combination of nebulized ...

Mylan Announces Tentative FDA Approval Under PEPFAR for Tenofovir Disoproxil Fumarate Tablets

PITTSBURGH, Dec. 4 /PRNewswire-FirstCall/ -- Mylan Inc. (NYSE: MYL ) today announced that Matrix Laboratories Limited* has received tentative approval from the U.S. Food and Drug Administration (FDA) under the President's Emergency Plan for AIDS Relief (PEPFAR) for its Abbreviated New Drug Ap...

NCCN Updates Infection Guidelines to Include Information About H1N1 Virus (Swine Flu)

...include the addition of doripenem (Doribax(R), Ortho-McNeil-Janssen Pharmaceuticals, Inc.) to the Antibacterial Agents Tables and tenofovir disoproxil fumarate (Viread(R), Gilead Sciences, Inc.) to the Antiviral Agents Tables. NCCN Clinical Practice Guidelines in Oncology(TM) are developed and updated...

St. Louis Named Top Asthma Capital for 2009

...physician." (6) A full report of the rankings, which was sponsored by a grant from AstraZeneca, the makers of SYMBICORT(R) (budesonide/formoterol fumarate dihydrate), is available at www.asthmacapitals.com . Top 2009 Asthma Capitals The top 10 Asthma Capitals for 2009, considered to be the m...

Warner Chilcott and Watson Pharmaceuticals Announce Agreements on Loestrin(R) 24 and Femcon(R) Fe Patent Litigation

...acetate and ethinyl estradiol tablets, USP and ferrous fumarate tablets) and Femcon(R) Fe (norethindrone, ethinyl estradiol tablets, chewable, ferrous fumarate tablets). The agreement covering Loestrin(R) 24 Fe will permit Watson to commence marketing its generic equivalent product on the earlier of January ...

Handa Pharmaceuticals Announces Submission of its First-to-File ANDA for AstraZeneca's SEROQUEL(R) XR

..."), a specialty pharmaceutical company based in Fremont, California, today confirmed that its Abbreviated New Drug Application ("ANDA") for Quetiapine fumarate Extended-Release Tablets, the generic version of AstraZeneca's SEROQUEL(R) XR, has been accepted for filing by the U.S. Food and Drug Administration (...

HIV prevention researchers to compare common ARV as a pill and vaginal gel in unique study

...e of three daily regimens of tenofovir tenofovir gel, tenofovir disoproxil fumarate tablets and the two together and the pharmacokinetics, or how the drug is ...rEP (oral tenofovir and oral Truvada, a combination of tenofovir disoproxil fumarate and another antiretroviral agent called emtricitabine). ...

AstraZeneca submits an sNDA for Symbicort for treatment of asthma in children as young as 6

... New Drug Application (sNDA) to the U.S. Food and Drug Administration (FDA) for approval of a new indication for SYMBICORT® (budesonide/formoterol fumarate dihydrate) Inhalation Aerosol for the long-term maintenance treatment of asthma in pediatric patients ages 6 to 11 years old. SYMBICORT is currently a...

Short-term use of antipsychotics in older adults with dementia linked to serious adverse events

...a report in the May 26 issue of Archives of Internal Medicine, one of the JAMA/Archives journals. Newer antipsychotic drugs (olanzapine, quetiapine fumarate and risperidone) have been on the market for more than a decade and are commonly used to treat the behavioral and psychological symptoms of dementia, ...

Concomitant use of Perforomist & tiotropium -- significant improvements -- COPD

...y with Perforomist Inhalation Solution (formoterol fumarate inhalation solution; FFIS), delivered by nebulizat... the results from Addition of Nebulized Formoterol fumarate to Tiotropium Treatment Relieves Dyspnea and Sympt...oncomitantly with Perforomist nebulized formoterol fumarate and tiotropium over tiotropium alone, said Dr. Tas...
Fumarate in Medical Technology

Schering-Plough Announces U.S. Filing of Mometasone Furoate/Formoterol Fumarate Combination for the Maintenance Treatment of Asthma

KENILWORTH, N.J., July 22 /PRNewswire-FirstCall/ -- Schering-Plough today announced that a New Drug Application (NDA) for a fixed-dose combination of mometasone furoate and formoterol fumarate has been filed in the United States and accepted for review by the U.S. Food and Drug Administration...

Concomitant Treatment With Nebulized Formoterol Fumarate and Tiotropium Provides Clinically Significant Improvements for COPD Patients

- Study shows significantly improved bronchodilation and symptom control with combination therapy - NAPA, Calif., May 20 /PRNewswire/ -- A newly published study presents data demonstrating that patients with Chronic Obstructive Pulmonary Disease (COPD), including emphysem...

Concomitant Use of Nebulized Formoterol Fumarate and Tiotropium Provides Significant Improvement in Dyspnea, COPD Symptoms and Rescue Medication Use over Tiotropium Alone

-- Clinical trial data for Perforomist(TM) (Formoterol Fumarate) Inhalation Solution presented at International ATS Conference -- NAPA, Calif., May 20 /PRNewswire/ -- Data presented today at the International Conference of the American Thoracic Society (ATS) demonstrate that concomitant ...

European Commission Approves ATRIPLA(R) (efavirenz 600 mg/emtricitabine 200 mg/tenofovir disoproxil fumarate 300 mg), the First Once-Daily Single Tablet Regimen for Virologically Suppressed Adults With HIV-1 Infection

- Product Developed Through Joint Venture Between Bristol-Myers Squibb and Gilead Sciences, the First of Its Kind in HIV Treatment - PRINCETON, N.J. and FOSTER CITY, Calif., Dec. 17 /PRNewswire-FirstCall/ -- The European Commission has granted marketing authorization for ATRIPLA(R) (efavi...

Bristol-Myers Squibb and Gilead Sciences Expand Their Alliance to Include Commercialization of ATRIPLA(R) (efavirenz 600 mg/emtricitabine 200 mg/tenofovir disoproxil fumarate 300 mg) in Europe

PRINCETON, N.J. and FOSTER CITY, Calif., Dec. 11 /PRNewswire-FirstCall/ -- Bristol-Myers Squibb Company (NYSE: BMY ) and Gilead Sciences, Inc. (Nasdaq: GILD ) today announced an agreement to commercialize ATRIPLA(R) (efavirenz 600 mg/emtricitabine 200 mg/tenofovir disoproxil fumarate 300 mg)...

European CHMP Issues Positive Opinion for ATRIPLA(R) (efavirenz 600 mg/ emtricitabine 200 mg/tenofovir disoproxil fumarate 300 mg)

- Once Granted by the European Commission, ATRIPLA Would Represent the First and Only Once-Daily Single Tablet Regimen for Many HIV/AIDS Patients in the European Union - PRINCETON, N.J., FOSTER CITY, Calif. and WHITEHOUSE STATION, N.J., Oct. 18 /PRNewswire-FirstCall/ -...

Health Canada Approves ATRIPLA(R) (efavirenz 600 mg/emtricitabine 200 mg/ tenofovir disoproxil fumarate 300 mg), the First Once-Daily Single Tablet Regimen for HIV

- Product Developed Through Joint Venture Between Bristol-Myers Squibb Company and Gilead Sciences, the First of Its Kind in HIV Treatment - PRINCETON, N.J. and FOSTER CITY, Calif., Oct. 17 /PRNewswire-FirstCall/ -- Bristol-Myers Squibb Company (NYSE: BMY ) and Gilead Sciences, Inc. (Nasd...

Tibotec Pharmaceuticals Announces Agreement to Develop and Commercialize a New Fixed-Dose Combination of TMC278 and Truvada(R) With Gilead Sciences

...oside reverse transcriptase inhibitor (NNRTI) TMC278 (rilpivirine hydrochloride 25 mg) and Gilead's Truvada (emtricitabine 200 mg/tenofovir disoproxil fumarate 300 mg) for treatment-naive adult patients with HIV-1. Fixed-dose combinations contain multiple medicines formulated into one tablet and help to simp...

PARI LC Plus and PRONEB Ultra Used in Two Perforomist Studies on Improving COPD Therapies

...ra II) were used to show that nebulized formoterol fumarate (Perforomist, DEY LP, Mylan Inc.) improves pulmona...er control of their COPD with nebulized formoterol fumarate delivered by PARI's LC Plus and PRONEB Ultra II. T...search and Opinion , compared nebulized formoterol fumarate to ipratropium/albuterol delivered via a metered d...

AstraZeneca Responds to FDA Joint Advisory Committees' Recommendation on SYMBICORT(R)

...uded that the benefits of AstraZeneca's SYMBICORT(R) (budesonide/formoterol fumarate dihydrate), a combination LABA/Inhaled Corticosteroid (ICS) medication, out... About SYMBICORT in the U.S. SYMBICORT(R) (budesonide/formoterol fumarate dihydrate) is approved in over 100 countries for the long-term maintenance ...
Fumarate in Biological News

Common allergy drug reduces obesity and diabetes in mice

...ic mice and, for a period of two months, treated them with either ketotifen fumarate (also called Zaditor) or cromolyn, both over-the-counter allergy drugs. ...so work for people?" Shi now intends to test both cromolyn and ketotifen fumarate on obese and diabetic non-human primates. Beyond friendly fire In...
Fumarate in Biological Technology

Nebulized Formoterol Fumarate Has Comparable Pharmacokinetic and Pharmacodynamic Profile to Dry Powder Formulation

- Data from two clinical trials presented at International ATS Conference - NAPA, Calif., May 20 /PRNewswire/ -- Data presented today at the International Conference of the American Thoracic Society (ATS) demonstrate that Perforomist(TM) Inhalation Solution (formoterol fumarate inhalation soluti...

Mylan Reports Adjusted Diluted EPS of $0.32 for the Quarter Ended June 30, 2009

...22.8 million, an increase of 16.0% from third-party sales of $105.9 million for the three months ended June 30, 2008. Perforomist(R), Dey's Formoterol fumarate Inhalation Solution (Perforomist), and EpiPen(R), Dey's Epinephrine auto-injector (EpiPen), were the primary drivers of the increase in revenues. ...

Mylan's Matrix Receives First Tentative FDA Approval Under PEPFAR for Generic Truvada(R)

...ated New Drug Application (ANDA) for Emtricitabine and Tenofovir Disoproxil fumarate Tablets, 200 mg/300 mg. Mylan Vice Chairman and CEO Robert J. Coury sa...ity anti-retroviral franchise." Emtricitabine and Tenofovir Disoproxil fumarate Tablets are the generic version of Gilead Sciences Inc.'s Truvada(R) Tablet...

FDA Approves SYMBICORT(R) for Chronic Obstructive Pulmonary Disease (COPD)

...stCall/ -- AstraZeneca (NYSE: AZN ) today announced that the U.S. Food and Drug Administration (FDA) has approved SYMBICORT (budesonide/formoterol fumarate dihydrate) 160/4.5 mcg for the twice daily maintenance treatment of airflow obstruction in patients with chronic obstructive pulmonary disease (COPD),...

Mylan Reports Adjusted Diluted EPS of $0.26 for the Quarter Ended Dec. 31, 2008, and Adjusted Diluted EPS of $0.80 for the Year Ended Dec. 31, 2008

... months ended Dec. 31, 2007. While Dey realized an increase in revenues from sales of both its epinephrine auto-injector EpiPen(R) and its formoterol fumarate inhalation solution, Perforomist(R), Specialty revenues were negatively impacted by the entrance into the market of generic competition on Dey's DuoNe...

AstraZeneca Submits sNDA for SEROQUEL XR(TM) for the Treatment of Major Depressive Disorder

... development programs are ongoing and regulatory filings are planned for SEROQUEL XR in other indications. Launched in 1997, SEROQUEL(R) (quetiapine fumarate tablets) has been prescribed to millions of patients worldwide. It is approved in 88 countries for the treatment of schizophrenia, in 79 countries for...

Warner Chilcott and Watson Pharmaceuticals Announce Launch of Tilia(TM) Fe

...etween Warner Chilcott and Watson Pharma, Inc., Watson has launched Tilia(TM) Fe (norethindrone acetate and ethinyl estradiol tablets, USP and ferrous fumarate tablets), the generic version of Warner Chilcott's oral contraceptive Estrostep(R) Fe. Under the terms of the agreement, Warner Chilcott will supply ...

PARI Respiratory's LC PLUS & PRONEB Ultra Deliver Dey, L.P.'s New COPD Therapy; Perforomist Launched Yesterday

...many of DEY's products -- including DuoNeb, AccuNEB, and now Perforomist," said Geoff A. Hunziker, President of PARI in the United States. Formoterol fumarate is a rapid, long-acting beta(2)-agonist (LABA) that has been previously available in the U.S. as a dry powder formulation and has twenty years of worl...

Mylan Inc. Subsidiary, Dey, L.P., Announces that Perforomist(TM) (Formoterol Fumarate) Inhalation Solution is Now Available for Maintenance Treatment of COPD

...ronchitis patients to benefit from rapid, long-lasting symptom control with twice-daily dosing of first nebulized formoterol fumarate - NAPA, Calif., Oct. 8 /PRNewswire-FirstCall/ -- Dey, L.P., a subsidiary of Mylan Inc. (NYSE: MYL ), today announced the launch of Perforomist(TM) ...
Fumarate in Biological Definition

Citric acid cycle

...Hydrolysis GDP + P i GTP + CoA-SH VII. Succinate 7. Succinate dehydrogenase Oxidation FAD FADH 2 VIII. fumarate 8. Fumarase Addition ( H 2 O ) H 2 O IX. L - Malate 9. Malate dehydrogenase Oxidation NAD + NADH + H + X...

Citric acid cycle

...Hydrolysis GDP + P i GTP + CoA-SH VII. Succinate 7. Succinate dehydrogenase Oxidation FAD FADH 2 VIII. fumarate 8. Fumarase Addition ( H 2 O ) H 2 O IX. L - Malate 9. Malate dehydrogenase Oxidation NAD + NADH + H + X...

Urea cycle

...P PP i + H 2 O → 2 P i argininosuccinate → arginine + fumarate ( catalyzed by argininosuccinase) arginine + H 2 O → ornithine...reaction: 2 NH 3 + CO 2 + 4 ATP + aspartate → urea + fumarate + 4 ADP + 4 P i External Links http://www.ncbi.nlm.nih.gov...
Fumarate in Biological Dictionary

Urea

...ief nitrogenous urea cycle n. The sequence of chemical reactions that takes place in the liver and that results in ... 3 ATP + 2 H2O urea + fumarate + 2 ADP + 4 Pi ... Describes forms and uses of fertilizer urea , how and when to apply it, and the ... Today, though, considerable urea is manuf...

Polysaccharide

...effects, drug interactions, warnings, and patient ... ... I take ferrous fumarate and iron polysaccharide ? What happens if I miss a ... What are the possible side effects of ferrous fumarate and iron polysaccharide ? ... POLYSACCHARIDE -IRON COMPLEX is an iron ...
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