Molecule aids fight E. Coli Infections
...of the defense tactics of the immune system of the fruitfly Drosophila led investigators to pinpoint a molecul...f this paper is they've been able to solve how the fruitfly responds to the E. coli bacteria and to show the r...hough there are similarities between the human and fruitfly defense systems, "somehow too many investigators a...Vastox Awarded £400,000 Grant to Support R&D at Carbohydrate Chemistry Facility
...ombine world-class expertise in both medicinal and carbohydrate chemistry with high-volume, high-content screening using its proprietary zebrafish and fruitfly technologies (chemical genomics). These whole organism screens have the potential to dramatically decrease the time and cost of drug discovery and dev...Tumor suppressor gene in flies may provide insights for human brain tumors
...rotein in the fly's brain, with a counterpart in mammals, that can apparently prevent brain tumors from forming. "Our data explicitly show that the fruitfly protein PP2A (protein phosphatase 2A) suppresses brain tumor formation and controls the balance of self-renewal and differentiation of neural stem cel...Genetic based human diseases are an ancient evolutionary legacy
...olutionary processes. Although it was already known that many disease associated genes occur also in other organisms distant to humans, such as the fruitfly Drosophila or the round worm Caenorhabditis, the analysis of Domazet-Loo and Tautz shows now for the first time that this is systematically true for t...Like father, like son: Attractiveness is hereditary
... in Current Biology, shows that attractiveness is hereditary. The research team, based on the University of Exeters Cornwall Campus, focused on the fruitfly Drosophila simulans. They paired up males and females at random and found the length of time it took for them to mate ranged from just two minutes to ...Corals -- More complex than you?
...rnover times ?like fruit flies ?shed genes particularly fast. Corals which take at least 5years to reach sexual maturity (compared with the laboratory fruitfly whose generation lasts only 3-4 weeks), and which have long and overlapping generation times, may thus be a living ‘museum?of ancestral animal genes....Brain region linked to fly slumber
...by Ravi Allada, assistant professor of neurobiology and physiology, shows that the so-called mushroom bodies are essential for sleep regulation in the fruitfly Drosophila melanogaster. (In the same issue, a second study, led by Amita Sehgal of the Howard Hughes Medical Institute, produced similar results usin...Parkinson's disease mechanism discovered
... The researchers next studied whether enhancing activity of the mammalian Ytp1p counterpart, called Rab1, suppressed alpha-synuclein toxicity in the fruitfly Drosophila, the roundworm C. elegans and in cultures of rat neurons. Bonini and her colleagues tested the effect in fruitflies; co-author Guy Caldwell...Researchers identify genes in fruitflies that may shed light on human cancer spread
... By searching through all the genes in the fruitfly genome, Johns Hopkins scientists have identified t...ntially turned on in so-called border cells of the fruitfly ovary that migrate during normal development. Two ...ination." Although border cell migration in the fruitfly ovary may seem a far stretch for studying human ca...How Fruitflies Know It's Time for Lunch
...bolic need, while external signals relay information about the quality of available food, determined by its smell and taste. Scientists studying the fruitfly Drosophila have traced the path of olfactory signals beginning with chemical receptors in the mouth, which set off neurons that signal the antennal lo...Reversal of role for a viral protein associated with the development of lymphoma
...e experimental data with computational and phylogenetic analyses of several fruitfly and other insect species. "Our experimental results agreed with the com...by Lopez also indicate that recursive splicing plays a role in at least 124 fruitfly introns, with up to seven potential cutting steps identified for a single i...