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FlashPlate in Medical Products

ViewLux ultraHTS Microplate Imager

Description:...rad modes-- the first system with true high throughput processing of radiometric assays, by exploiting the high quantum efficiency of the latest Image flashplate technology....
Company:PerkinElmer Life And Analytical Sciences, Inc.
FlashPlate in Biological Technology

Evaluation of FlashPlate in a Helicase Assay

Abstract This study demonstrated the efficacy of the FlashPlate as a high throughput screening (HTS) platform for a helicase functional assay. Helicase activity was measured on a streptavidin coated FlashPlate (SMP103), using two DNA oligos. One of the oligos was biotinylated;...

Use of FlashPlate Technology for In Vitro Measurement of 125I-Labeled TGF-1 Binding on Chimeric Extracellular Domain of Type II Transforming Growth Factor Receptor

Sylviane Komesli, Martine Page, and Patrick Dutartre Dpartement dImmunologie, Laboratoires Fournier S.A., France Abstract TGF- type I and type II receptors form ligand dependent heteromeric signaling complexes, in which transforming growth fact...

Use of Novel FlashPlate Technology to Measure cAMP Accumulation in Chinese Hamster Ovary Cells Expressing Human -2 Adrenoreceptors

J. Watson SmithKline Beecham Pharmaceuticals, UK Introduction Due to recent technologies in the pharmaceutical industry that have resulted in an increase in the production of potential drug candidates, it has become vital that screening assays are high th...

Use of FlashPlate Technology for In Vitro Measurement of [35S]-GTPγS Binding in CHO Cells Expressing the Human 5-HT1B Receptor

J. Watson and J.V. Selkirk SmithKline Beecham Pharmaceuticals, UK Abstract FlashPlate is a 96-well white polystyrene microplate with scintillant-coated wells designed for highvolume, in-plate radiobinding assays. This study investigates the use...

In Vitro Measurement of the Second Messenger cAMP: RIA vs. FlashPlate

Introduction Abnormalities in neurotransmission within the brain can lead to several disease states, including anxiety, depression or schizophrenia. Extensive research has been carried out to discover the mode of action of various transmitters, in order to understand and comba...

Development of Radioligand Binding Assays for the Motilin Receptor Using ScreenReady Targets.

...r detection of ligand-receptor interactions. Using flashplate microplates as the homogeneous platform, we have...d efficient immobilization of recombinant GPCRs on flashplate microplates. Assays are microformatted to a minimu...formatted to 50 μl. Membrane-coated flashplate microplates are supplied with the appropriate Perk...

Counting FlashPlates on the Wallac MicroBeta

...bes, one above the sample and one below. flashplate is a solid white plate and so MicroBeta measuremen...ce is made when measuring the same assay with both flashplate and ScintiPlate. APPLICATION I ...se Assay was performed using a Streptavidin coated flashplate (SMP103). In this assay, a biotinylated DNA oligon...

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