Innate immune system targets asthma-linked fungus for destruction
...roup for proteomics and functional genomics will be invaluable in this respect. We suspect that the dysregulated immune responses to Alternaria, other filamentous fungi, and perhaps chitin-encased insects, such as mites and cockroaches, may play a pivotal role in chronic inflammation and the subsequent developme...Protein-dependent 'switch' regulates intracellular trafficking in epithelial cells
...the outer surface, where the cell interacts with its environment," Dr. Kreitzer explains. These kinesin "trains" work by moving their cargoes along filamentous tracks, known as microtubules. "When everything is working right, appropriate surface markers end up where they need to go. However, in rare cases, mi...How Candida albicans transforms from its normally benign form into life-threatening form
...e fungus starts its 'attack' on a patient by changing its oval shape into a filamentous form, which has thin, threadlike appendages emerging from the cell body. Wa... to start the transformation from the harmless oval shape to the infectious filamentous form. "One question remained, however - how does it activate the cellul...Bak Protein Sets Stressed Cells on Suicide Path
...and used the common chemotherapeutic agent cisplatin, then documented that filamentous mitochondria became fragmented very early and quickly in apoptosis. ...ria-shaping proteins called mitofusins, which help mitochondria keep their filamentous shape in non-stressed cells. Dr. Dong suspects Bak may also play a role in...Selective Marker Found to Indicate Aggressive Form of Breast Cancer
...ited mutations in BRCA1 display the basal phenotype, DiRenzo and colleagues found high levels of nestin in these tumors as well. Nestin is a long filamentous protein found in adult stem cells in the central nervous system. While scientists do not know its exact function, the protein is thought to have a rol...Selective Marker Found to Indicate Aggressive Form of Breast Cancer
...ed mutations in BRCA1 display the basal phenotype, DiRenzo and colleagues found high levels of nestin in these tumors as well. Nestin is a long filamentous protein found in adult stem cells in the central nervous system. While scientists do not know its exact function, the protein is thought to have a rol..."Anti Aging" Skin Cream Developed at Clarkson University
...f aging, such as hardening of the arteries, joint stiffness, cataracts, Alzheimer’s and dementia. The Clarkson team observed the increasing density of filamentous fibers, known as f-actin, is a major source of the increasing rigidity. Sokolov used the Internet to research the process for making homemade em...Reviews of microbial gene language published in special issue of Trends in Microbiology
... and lead to disease. They include descriptions of bacterial effector proteins, virulence factors, effector protein delivery systems, and infection by filamentous pathogens. Joo Setubal, Associate Professor at the Virginia Bioinformatics Institute, remarked: "Symbiotic microbes have developed many ingenious ways...Unusual microbial ropes grow slowly in cave lake
... Deep inside the Frasassi cave system in Italy and more than 1,600 feet below the Earth's surface, divers found filamentous ropes of microbes growing in the cold water, according to a team of Penn State researchers. "Sulfur caves are a microbiology paradise. Many differen...Research about plant viruses could lead to new ways to improve crop yields
...destructive group of plant viruses known: flexible filamentous viruses. The cost of worldwide crop losses due...s (after fungi). The 300-plus species of flexible filamentous viruses are responsible for more than half of all ...w-resolution structures of two species of flexible filamentous viruses: soybean mosaic virus and potato virus X. ...Structures of important plant viruses determined
... UPTON, NY - Flexible filamentous viruses make up a large fraction of known plant viruses and are responsible for more than half the viral damage to crop plants throughout the world. N...US Department of Energy Joint Genome Institute announces new genome sequencing projects
...lulose, and lignin. Many microorganisms are capable of utilizing cellulose and hemicellulose as carbon and energy sources, but a much smaller group of filamentous fungi has evolved with the ability to depolymerize lignin, the most recalcitrant component of plant cell walls. Collectively known as white rot fungi,...Single-celled bacterium works 24-7
...y, the oxygen produced by photosynthesis degrades nitrogenase, making nitrogen fixation difficult or impossible in photosynthetic organisms. Other filamentous cyanobacteria perform photosynthesis and nitrogen fixation in different cells. As a single-celled bacterium, however, Cyanothece cannot separate these...Bacteria that cause urinary tract infections invade bladder cells
...eviously suggested that some bacteria progress to a filament-like shape when exiting out of the biofilm. Rosen was able to identify bacteria with this filamentous morphology in 41 percent of samples from patients with symptomatic UTIs. Neither indicator was detected in urine from women who did not have active...Stem cell nuclei are soft 'hard drives,' Penn study finds
..., followed by hematopoietic stem cells, HSCs, that generate a wide range of blood and tissue cells. Both types of stem cells lack lamins A and C, two filamentous proteins that interact to stabilize the inner lining of the nucleus of most tissue cells. Lamins A and C stiffen cell nuclei and are expressed in cel...A tiny pinch from a 'z-ring' helps bacteria cells divide
...ed bacteria during cell division. The researchers knew that each rod-shaped bacterium possesses, around the inside of its midsection, a belt made of a filamentous protein called FtsZ. Most of the time, this ring is inactive. But when a bacterium cell is healthy and has sufficient food, it seeks to reproduce by d...Transformation of Filamentous Fungi by High-Voltage Electroporation
Contributed by G.H. Goldman, R. Geremia, M. Van Montagu, and A. Herrera-Estrella, Laboratorium voor Genetica, Rijksuniversiteit Gent, B-9000 Gent, Belgium Introduction Virtually all fungal transformation protocols call for the addition of ...Transformation of Filamentous Fungi by Microprojectile Bombardment
Roland W. Herzog, Molecular Genetics Program, Department of Botany and Microbiology, 101 Life Sciences Building, Auburn University, AL 36849-5407, USA Introduction The vast majority of transformation protocols for filamentous fungi are ...Efficient Transfection of Neurospora Crassa
... INTRODUCTION: The diverse reproductive capabilities and the nutritional conventions of Neurospora crassa have made this filamentous fungus a model organism in the field of molecular biology and genetics for more than a half a century. In fact, N. crassa was us...Efficient Transfection of Neurospora Crassa
... INTRODUCTION: The diverse reproductive capabilities and the nutritional conventions of Neurospora crassa have made this filamentous fungus a model organism in the field of molecular biology and genetics for more than a half a century. In fact, N. crassa was us...