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fibrosis in Medical News

Genetic Breakthrough Spells Hope for Lung Fibrosis Patients

Might help those with advanced disease buy time until transplant, study shows WEDNESDAY, July 8 (HealthDay News) -- Genes that can help doctors predict when patients with idiopathic pulmonary fibrosis are becoming seriously ill have been identified by U.S. researchers, who said the fin...

All Fifty States to Screen Newborns for Cystic Fibrosis by 2010

BETHESDA, Md., July 7 /PRNewswire-USNewswire/ -- The Cystic Fibrosis Foundation announced today that all 50 states plus the District of Columbia have passed legislation requiring that all newborns be screened for cystic fibrosis (CF) by the year 2010. Early diagnosis of cystic fibrosis, a li...

Cystic Fibrosis Treatment May Cause Hearing Loss

Ear evaluation urged for youngsters taking common antibacterial medication THURSDAY, July 2 (HealthDay News) -- A common antibacterial treatment for cystic fibrosis can cause sensorineural hearing loss, finds a new study. Researchers reviewed the medical records of 50 cystic fibrosi...

Women with cystic fibrosis can have safe and successful fertility treatment

Amsterdam, The Netherlands: Women with cystic fibrosis can have fertility treatment to help them have babies without any long-term adverse effects on either themselves or their children, according to new research presented at the 25th annual meeting of the European Society of Human Reproduction an...

CPF Announces Dates for Seventh Annual National Pulmonary Fibrosis Awareness Week

2009 Awareness Efforts Set for August and September, PF Week Sept. 14 - 21 SAN JOSE, Calif., June 25 /PRNewswire-USNewswire/ -- The Coalition for Pulmonary Fibrosis (CPF) announced today it has scheduled its 2009 National Pulmonary Fibrosis (PF) Awareness Week for September 14-21, 2009. Th...

CPF, Pulmonary Fibrosis Experts Guests on Sirius and XM Satellite Radio Show June 16th

"Doctor Radio" Host Interviews CPF Co-Founder, PF Advocate, and Top PF Researcher and Clinician NEW YORK, June 15 /PRNewswire-USNewswire/ -- The Coalition for Pulmonary Fibrosis (CPF) today announced its co-founder and other Pulmonary Fibrosis (PF) experts will be guests on the Sirius and XM ...

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fibrosis in Medical Technology

Cystic Fibrosis - Liposomal Tobramycin Receives Second Orphan Drug Designation Within Weeks

ZURICH, July 16 /PRNewswire/ -- An innovative treatment for infections of the respiratory tract in cystic fibrosis patients has received a second orphan drug designation in the US only weeks after a first designation was granted. The recent designation relates to Burkholderia cepacia pathogens...

Transave Receives $2.2 Million Cystic Fibrosis Foundation Award for Development of ARIKACE(TM)

Company Also Receives Patent Covering ARIKACE for Once-Daily Treatment of Pseudomonas Lung Infections MONMOUTH JUNCTION, N.J., June 25 /PRNewswire/ -- Cystic Fibrosis Foundation Therapeutics Inc., the nonprofit affiliate of the Cystic Fibrosis Foundation, has provided a $2.2 million award to ...

Pharmaxis Announces Positive Results of Phase 3 Cystic Fibrosis Trial

SYDNEY, Australia, May 4 /PRNewswire-Asia-FirstCall/ -- Pharmaceutical company Pharmaxis (ASX: PXS; Nasdaq: PXSL ) is pleased to announce positive results of its recently completed international Phase III trial of Bronchitol(TM) in people with cystic fibrosis. The study represents one of th...

Cystic Fibrosis - Orphan Drug Designation for Innovative Treatment Against Lung Infections by Axentis Pharma AG

ZURICH, Switzerland, April 30 /PRNewswire/ -- An innovative treatment for infections of the respiratory tract in cystic fibrosis patients has received orphan drug designation in the US. Axentis Pharma of Zurich, Switzerland announced today that this sought-after designation has been granted to...

PTC Announces Data Showing That PTC124 Causes Statistically Significant Improvements in Chloride Channel Function in Cystic Fibrosis Patients

- PTC124 Highlighted in Multiple Presentations at North American Cystic Fibrosis Conference - SOUTH PLAINFIELD, N.J. and ORLANDO, Fla., Oct. 24 /PRNewswire/ -- PTC Therapeutics, Inc. (PTC) today announced that results from a randomized Phase 2a European study demonstrated that treatment with...

Cystic Fibrosis Axentis Pharma Initiates Clinical Trial for Lung Infections

ZURICH, Switzerland, September 4 /PRNewswire/ -- Axentis Pharma AG has initiated a clinical phase IIa trial to assess the safety and tolerability of a new therapeutic formulation for the treatment of severe pulmonary infection in cystic fibrosis patients. The new formulation allows an establis...
fibrosis in Medical Products

Cystic Fibrosis Mutation Panel with Reflex to CFTR Full Gene Analysis

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Cystic Fibrosis Cis-Trans

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Cystic Fibrosis 3199del6 Only(ARUP Medical Director or Genetic Counselor approval required prior to testing)

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Tag-It™ Cystic Fibrosis Kit

Description: Tm Bioscience introduces the Tag-It™ Cystic Fibrosis Kit, the first FDA cleared IVD for cystic fibrosis genotyping. With validated performance criteria, this highly accurate and reproducible (>99.9%) assay will provide superior mutation coverage for carrier screening in adults and as an aid t...
Company:Tm Bioscience Corporation

Tag-It Cystic Fibrosis ASPE Mix

Description: The Tag-It™ Cystic Fibrosis ASR reagents can be used by high complexity CLIA approved laboratories for detection of up to 70 mutations and 6 variants (polymorphisms) in the cystic fibrosis transmembrane conductance regulator (CFTR) gene....
Company:Tm Bioscience Corporation

Tag-It Cystic Fibrosis ASPE Mix B

Description: The Tag-It™ Cystic Fibrosis ASR reagents can be used by high complexity CLIA approved laboratories for detection of up to 70 mutations and 6 variants (polymorphisms) in the cystic fibrosis transmembrane conductance regulator (CFTR) gene....
Company:Tm Bioscience Corporation

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fibrosis in Medical Definition

Family history (medicine)

...th a known hereditary component, many healthy people are now tested early to prevent the symptoms from developing. This has become accepted in cystic fibrosis , hemochromatosis and various other disorders. References ^ Rich EC, Burke W, Heaton CJ, Haga S, Pinsky L, Short MP, Acheson L. R...

Pathology

...aberrent healing response can lead to progressive fibrosis , contractures, or other changes which can comprom...Other Alpha 1-antitrypsin deficiency - Cystic fibrosis - Amyloidosis ( Familial Mediterranean fever ) ...iosis - Pneumoconiosis - Silicosis - Bauxite fibrosis - Berylliosis - Siderosis - Byssinosis - H...
fibrosis in Medical Dictionary

Pulmonary Fibrosis

Interstitial lung disease (ILD), also known as diffuse parenchymal lung disease (DPLD), refers to a group of lung diseases affecting the interstitium . It concerns alveolar epithelium, pulmonary capillary endothelium,... Idiopathic pulmonary fibrosis (IPF), formerly known as cryptogenic...

Cystic fibrosis

Cystic fibrosis is a genetic disorder known to be an inherited disease of the secretory glands, including the glands that make mucus and sweat. Information for cystic fibrosis families and patients including forums, online newsletter, articles, therapies, and other resources. ...

Trypsinogen

... trypsinogen test ... Immunoreactive trypsinogen (IRT) is used as part of a ... Overview of the trypsinogen test, used to screen for cystic fibrosis and evaluate pancreatic function ... Formal name: Immunoreactive trypsinogen ... Trypsinogen is a precursor of trypsin, an enzyme produced ...

Systemic sclerosis

...ximately 5 ... festations of systemic sclerosis range from localized skin ... Systemic sclerosis is characterized by. inflammation and fibrosis leading to changes in the ... Frankly it is terrifying to have this diagnosis but at the same time I at last know what is happening and that I a...

Silicosis

...20 years) ... Accelerated silicosis -- occurs after exposure to larger amounts of silica over ... Silicosis results in conditions such as lung fibrosis and emphysema. The form and severity in which silicosis manifests itself depend on the type and ... 2) Accelerated silicosis ... Through pass...

Scleroderma

... Scleroderma is a chronic autoimmune disease characterized by fibrosis (or hardening), vascular alterations, and autoantibodies. There are two major forms: Limited cutaneous scleroderma (or morphea) mainly affects t...
fibrosis in Biological News

Pitt team first to profile genes in acutely ill idiopathic pulmonary fibrosis patients

PITTSBURGH, July 7 The first findings from a one-of-a-kind, patient-driven effort to provide lung tissue for research might help doctors predict when patients with idiopathic pulmonary fibrosis (IPF) are becoming dangerously ill and also could point the way to interventions that could sustain the...

Cystic fibrosis testing -- next steps

San Juan Capistrano, CA and Chantilly, VA Three reports describing advances in cystic fibrosis genetic testing appear in the May 2009 issue of The Journal of Molecular Diagnostics . Cystic fibrosis is a hereditary disease that affects mucus secretions in the lungs, liver, pancreas, and intes...

Two-pronged model could help foil tough cystic fibrosis infections

Hanover, NH--Dartmouth Medical School researchers have devised a novel approach for thwarting the relentless bacterial infections that thrive in the lungs of people with cystic fibrosis (CF), unlocking new possibilities against a tenacious and toxic hallmark of the common genetic disease. Combi...

Nanoemulsion potent against superbugs that kill cystic fibrosis patients

ANN ARBOR, Mich. University of Michigan scientists report highly encouraging evidence that a super-fine oil-and-water emulsion, already shown to kill many other microbes, may be able to quell the ravaging, often drug-resistant infections that cause nearly all cystic fibrosis deaths. Cystic fi...

New test promises quicker, more accurate evaluation for cystic fibrosis patients

Researchers at National Jewish Health have identified a simple gene-based blood test that more accurately and quickly measures cystic fibrosis patients' response to therapy than current tests. The test, a measure of inflammatory gene expression, could improve patient care and help clear a backlog ...

New approach to treating cystic fibrosis lung infection shows promise

Toronto, ON (September 22, 2008) Researchers at the University of Calgary have found a new method of fighting severe lung infections in people with cystic fibrosis (CF). These findings are published in Proceedings of the National Academy of Science USA, this week. Communities of bacteria gr...

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fibrosis in Biological Technology

Phase 3 Cystic Fibrosis Trial Results Presented at European Conference

SYDNEY, June 16 /PRNewswire-Asia/ -- Pharmaceutical company Pharmaxis (ASX: PXS; Nasdaq: PXSL ) is pleased to announce that additional results of its recently completed international Phase III trial of Bronchitol in patients with cystic fibrosis have been presented at the 2009 European Cysti...

Study Finds Noninvasive Blood Test for Liver Fibrosis May Alleviate Need for Liver Biopsies for Some Patients with Chronic Hepatitis C

MADISON, N.J., June 8 /PRNewswire-FirstCall/ -- A study in the June issue of Clinical Gastroenterology and Hepatology , published by Elsevier, demonstrates that the Hepascore(TM) liver fibrosis blood-serum test panel may help physicians more accurately diagnose and stage liver fibrosis in patie...

Pigs bred with cystic fibrosis provide model to mimic human disease

COLUMBIA, Mo. Cystic Fibrosis (CF) continues to be a lethal disease for humans despite the identification of the problematic gene two decades ago. Many humans born with CF the most common genetic disease in Caucasians - often die because of a lung disease developed later. Scientists have been un...

40 High-Achieving Students with Cystic Fibrosis Receive $100,000 Total in Higher Education Scholarships From SolvayCARES(SM)

- One Outstanding Student to Become the SolvayCARES Thriving Student Achiever and Receive $10,000 to Further Academic Goals - MARIETTA, Ga., Sept. 15 /PRNewswire/ -- Solvay Pharmaceuticals, Inc. has awarded scholarships totaling $100,000 to 40 students living with cystic fibrosis (CF)...

Cystic Fibrosis - Axentis Pharma Takes Over Patents and Continues Development of Innovative Platform Technology

ZURICH, Switzerland, June 26 /PRNewswire/ -- The rights to key patents for an innovative screening tool for treatments for cystic fibrosis were transferred today to Swiss biotech company Axentis Pharma AG. The company has acquired the rights from an Austrian firm that has made a vital contribu...

Coalition for Pulmonary Fibrosis and American Thoracic Society Continue Research Partnership Through 2010

CPF and ATS to Jointly Award $200,000 in research funding TORONTO, May 21 /PRNewswire-USNewswire/ -- The Coalition for Pulmonary Fibrosis (CPF) and the American Thoracic Society (ATS), the world's leading professional organization for pulmonary, critical care and sleep physicians, today...
fibrosis in Biological Products

Endoplasmic Reticulum Isolation Kit from Sigma-Aldrich

Description:...ynthesis, degradation and metabolic pathway analysis. Metabolic abnornalities of ER include carnitine acetyltransferase deficiency in children, cystic fibrosis and many more ER protein retention discorders. Suitable for up to 50g of tissue. Features and Benefits: Specially formulated extraction reagents fo...
Company:Sigma-Aldrich
fibrosis in Biological Definition

Computed axial tomography

...disease (such as pneumonia ) or cancer , ordinary non-contrast scans are adequate. For evaluation of chronic interstitial processes ( emphysema , fibrosis , and so forth), thin sections with high spatial frequency reconstructions are used. For evaluation of the mediastinum and hilar regions for lympha...

Diabetes mellitus

...coronary artery disease , past gestational diabetes , polycystic ovary syndrome , chronic pancreatitis , hepatic steatosis (fatty liver), cystic fibrosis , several mitochondrial neuropathies and myopathies, myotonic dystrophy , Friedreich's ataxia , some of the inherited forms of neonatal hyperinsulin...

Gene therapy

...ists took the logical step of trying to introduce genes straight into human cells, focusing on diseases caused by single-gene defects, such as cystic fibrosis , hemophilia , muscular dystrophy and sickle cell anemia . However, this has been much harder than modifying simple bacteria, primarily because of...

Genetics

... 1989 The first human gene is sequenced by Francis Collins and Lap-Chee Tsui , it encodes the CFTR protein, defects in this gene cause cystic fibrosis 1995 The genome of Haemophilus influenzae is the first genome of a free living organism to be sequenced 1996 Saccharomyces cerevisiae is...

Guthrie test

... of the baby, at or before 4 days of age. The test typically screens for the following diseases: Phenylketonuria Hypothyroidism Cystic fibrosis Galactosemia ...

Human Genome Project

...sive and easy to administer genetic tests that can show predisposition to a variety of illnesses, including breast cancer , blood clotting , cystic fibrosis , liver diseases and many others. There are also many tangible benefits for biological scientists. For example, a researcher investigating a certa...
fibrosis in Biological Dictionary

Screening

... criminal background checks that are returned in seconds. The state report is $12.95 and the national is $16.95. Volume discounts available. Cystic fibrosis Foundation, Newborn Screening ... What does the newborn screening test for CF reveal? ... to encourage states to provide CF newborn screening ? ....

Muscularis

... TUBULAR GLANDS Often branched. Mucosa deepest ... Results: The usefulness of clinical and biochemical indices to define the ... higher degree of fibrosis in the submucosa and muscularis mucosae and ... tunica muscularis synonyms. tunica muscularis usage examples and tunica muscularis quot...

Longitudinal axis

...are fibrous bands or sheets of connective tissue linking ... Anterior Longitudinal . Axis – Sacrum. Extension & reinforces front of annulus fibrosis ... US6857147: Synchronization drive for a longitudinal axis telescopic guidance mechanism > ... guidance along a longitudinal axis in a...

Homozygote

...lled a homozygote . ... Online Medical Dictionary and glossary with medical definitions ... For example, a girl who is a homozygote for cystic fibrosis (CF) received the CF ... homozygote n. An organism that has the same alleles at a particular gene locus on homologous ... What is the diffe...

Gene therapy

...tor information, gene therapy jobs and educational reviews. Does anyone know how gene therapy is helping cystic fibrosis? Posted in Cystic fibrosis Gene Therapy about 1 year ago, 0 replies ... A gene therapy news and information community. ... Until now, attempts to use gene therapy ...

Chromosome jumping

...me jumping . Full text ... The use of chromosome jumping should now be applicable to any genetic locus for ... Identification of the cystic fibrosis gene: chromosome walking and jumping . ... Yeast artificial chromosome This is a photo of two copies of the Washington ... chromosome clone...
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