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Fibroblasts in Medical News

Video: New Online Film Introduces Longevinex Advantage(TM) -- The First Resveratrol-Based Dietary Supplement to Address Both Cellular and Connective Tissue Aging

...edients in Longevinex Advantage(TM), in particularly hyaluronan, a natural water-holding, nerve and joint cushioning molecule, stimulates cells called fibroblasts to resume youthful production of hyaluronan. The pure form of hyaluronan used in Longevinex Advantage(TM) has been shown in published studies to ...

Cardium Presents Gene Activated Matrix Technology and Update on Excellarate Clinical Development Program at ASGT Annual Meeting

...at PDGF-B is believed to stimulate angiogenesis and granulation tissue formation through the recruitment and proliferation of cells such as monocytes, fibroblasts and endothelial cells, which are critical for the effective stimulation of a variety of wound healing processes. The Excellarate product candidate re...

Cardium Reports on New Excellarate(TM) Product Formulations to Expand Commercialization Potential Into Multiple Wound Healing Applications

.... PDGF-B is believed to stimulate angiogenesis and granulation tissue formation through the recruitment and proliferation of cells such as monocytes, fibroblasts and endothelial cells, which are critical for the effective stimulation of a variety of wound healing processes. On May 6, 2009, Cardium announce...

New universal breast cancer marker predicts recurrence and clinical outcome

...expressed by cells in the stroma called fibroblasts, which are present in the connective tissue surrounding cancer cells. When cancer cells arise, the fibroblasts stop making caveolin-1. "The idea that a prognostic biomarker is present in the stroma rather than the epithelial cancer cell is paradigm-shifting,...

Scientists Find New Way to Create Stem Cells

...ery excited about this breakthrough in generating embryonic-like cells from fibroblasts [cells that give rise to connective tissue] without using any genetic mater...ly reprogram the adult cells. The reprogrammed embryonic-like cells from fibroblasts behaved the same as embryonic stem cells in terms of molecular and function...

iZumi Bio and Kyoto University Form Collaboration to Advance Induced Pluripotent Stem Cell Technology

...se by using four transgenes - Oct3/4, Sox2, Klf4 and c-Myc - delivered into fibroblasts via retroviral vectors, which became the world's first report of its kind. ...air of plasmid vectors to introduce the four iPS genes into embryonic mouse fibroblasts as part of CiRA's efforts to establish safe and efficient methods to genera...
Fibroblasts in Medical Technology

HEALTHPOINT-Sponsored Venous Leg Ulcer Clinical Trial Enrolls First Subject for Second Phase II Study

... Previous research strongly suggests that wound healing is accelerated by the application of living cells, particularly when both keratinocytes and fibroblasts are present together. By allowing the cells to be in contact with each other following spraying onto the wound surface, it is thought that growth prom...

Cardium Announces Completion of Patient Recruitment in Phase 2b Clinical Trial of Excellarate(TM) for the Potential Treatment of Diabetic Foot Ulcers

...ound site is believed to stimulate angiogenesis and granulation tissue formation through the recruitment and proliferation of cells such as monocytes, fibroblasts and endothelial cells. These cell types are critical for the effective stimulation of a variety of wound healing processes. MATRIX Study Comple...

New Study Using Combination of Bioengineered Skin and Stem Cells Shows Promise in Treatment of Non-Healing Wounds

...provided by bioengineered skin -- a bi-layered, substitute skin that consists of living human keratinocytes (cells that make the upper skin layer) and fibroblasts (cells that make collagen) -- derived from neonatal foreskin following a circumcision and preserved for medical research. From this initial study...

Isolagen Completes Pivotal Efficacy Portion of Phase III Studies of Isolagen Therapy(TM) for Wrinkles

...) is an innovative cellular processing system which creates a natural, living cell therapy. By multiplying a patient's own collagen-producing cells or fibroblasts into tens of millions of new cells, a personalized treatment is created which is then returned to the patient's skin. This treatment, known as the Iso...

Cardium and Tissue Repair Company's Excellarate Candidate for Healing Diabetic Wounds Gains Media Focus in Multiple Regions Across U.S.

...ound site is believed to stimulate angiogenesis and granulation tissue formation through the recruitment and proliferation of cells such as monocytes, fibroblasts and endothelial cells, which are necessary for the stimulation of a variety of wound healing processes. A previous Phase 1/2 clinical trial showed tha...

Isolagen, Inc. Completes Enrollment in Isolagen Therapy(TM) Phase II/III Acne Scar Study

...) is an innovative cellular processing system which creates a natural, living cell therapy. By multiplying a patient's own collagen-producing cells or fibroblasts into tens of millions of new cells, a personalized treatment is created which is then returned to the patient's skin. This treatment, known as the Iso...
Fibroblasts in Medical Products

Insulin Binding, Fibroblasts

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Carnitine Transport, Fibroblasts

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Repliform® Tissue Regeneration Matrix

Description:...generation Matrix is an acellular human dermal allograft that when surgically implanted is intended to function as a template, facilitating the body's fibroblasts to regenerate normal soft tissue rather than scar....
Company:Boston Scientific Corporation
Fibroblasts in Medical Dictionary

Keloids

...n Keloids are overgrowths of fibrous Keloids are raised, reddish nodules that develop at the site of an injury.After ... With keloids , the fibroblasts continue to multiply even after the wound is ... InteliHealth - Featuring Harvard Medical School's consumer health information. ... Keloids are ...
Fibroblasts in Biological News

Reprogramming human cells without inserting genes

...ed a novel way to turn on stem cell genes in human fibroblasts (skin cells) without the risks associated with ins...uction of Stem Cell Gene Expression in Adult Human fibroblasts without Transgenes," published online July 21, 200...ulture conditions alone, we can achieve changes in fibroblasts that would be beneficial in development of patient...

New trigger for chronic inflammation in rheumatoid arthritis discovered

...g in the joints by increasing levels of molecules that cause inflammation. The researchers took human immune cells called macrophages and cells called fibroblasts from the swollen joint of patients with rheumatoid arthritis and added tenascin-C. After the tenascin-C was added, the cells produced more molecules t...

Heart attacks: The tipping point

... "Seventy percent of the heart is made up of myocytes, which are contractile muscle cells. The remaining 30% is mostly rigid structural cells called fibroblasts that work to hold the muscle in place," Dr. Zlochiver explains. "As the heart ages and contends with factors such as high blood pressure or genetic di...

New method developed by UC San Diego bioengineers gives regenerative medicine a boost

...rogrammable chips into padlock probes. In the meantime, Zhang and his team plan to further their research in this area. "We have already compared fibroblasts with induced pluripotent stem cells, which was to examine what happened when we turned the clock back," he said. "The natural thing we want to do now ...

Locking parasites in host cell could be new way to fight malaria

...cess, Greenbaum worked with Roos, who has pioneered the use of T. gondii for a wide range of molecular genetic and cellular studies. Infecting mouse fibroblasts with T. gondii , the team used genetic techniques to remove, and restore, calpain activity. They found that in the absence of calpain, parasites coul...

Eye cells believed to be retinal stem cells are misidentified

...main adult ciliary epithelial cells. Dyer said that a particularly promising alternative is the possibility of taking samples of adult cellssuch as fibroblasts that form connective tissuefrom a patient with retinal degeneration and exposing them to genetic cues that induce them to revert to stem cells. Those ...
Fibroblasts in Biological Technology

Cardium Provides Update on Phase 2b Excellarate Clinical Study and Plans for Additional Tissue Repair Applications

...ound site is believed to stimulate angiogenesis and granulation tissue formation through the recruitment and proliferation of cells such as monocytes, fibroblasts and endothelial cells. These cell types are critical for the effective stimulation of a variety of wound healing processes. The Excellarate pr...

Histogen Hair Regrowth Clinical Trial Presented at ISHRS Annual Meeting

...tive medicine company developing solutions based on the products of newborn fibroblasts grown under embryonic conditions, shared the results of the Company's preli...gen's proprietary bioreactors that mimic the embryonic environment, newborn fibroblasts are encouraged to naturally produce the vital proteins and growth factors f...

Histogen Aesthetics Launches ReGenica Rejuvenation System

...sthetics products are based on Histogen's core technology, in which newborn fibroblasts are grown in a proprietary simulated embryonic environment. From this proce...gen's proprietary bioreactors that mimic the embryonic environment, newborn fibroblasts are encouraged to naturally produce the vital proteins and growth factors f...

Histogen to Present Preliminary Hair Regrowth Clinical Results at Stem Cell Summit

...eloping solutions based on the products of newborn fibroblasts grown under embryonic conditions, will address att...liquid formula created by the culturing of newborn fibroblasts in an embryonic-like environment, and then harvest...tors that mimic the embryonic environment, newborn fibroblasts are encouraged to naturally produce the vital prot...

David Bagley Joins Histogen as President

...s without the use of embryonic stem cells or animal products. Through Histogen's proprietary bioreactors that mimic the embryonic environment, newborn fibroblasts are encouraged to naturally produce the vital proteins and growth factors from which the company has developed its rich product portfolio. Histogen ha...

Histogen Featured on Economic Report Television Series

...hannel 7, on Saturday, December 6th, at 6:00am. Through Histogen's proprietary bioreactor process which mimics the embryonic environment, newborn fibroblasts are encouraged to naturally produce the vital proteins and growth factors from which the company has developed its rich product portfolio. Histogen ha...
Fibroblasts in Biological Products

normal human fibroblasts from Exalpha Biologicals, Inc.

Description: normal human fibroblasts Source: Cell Lysate Form: Ready to Use Application: Western Blotting Control...
Company:Exalpha Biologicals, Inc.

Anti-TIMP-4 (Tissue Inhibitor of Metalloproteinases-4), Loop #3 Polyclonal Antibody, Unconjugated from CHEMICON

Description:... Timp-4 has been reported in heart tissues, and is produced by some fibroblasts in cell culture conditions. Treatment of cells with phorbol ester TPA stimulates production of TIMP-4 in some cell types, but the low protein levels ...
Company:CHEMICON

Mouse Anti-Human Complex IV, assembly factor SURF1 Monoclonal Antibody, Unconjugated, Clone 21H2BG4 from MitoScience LLC

Description:...embly is incomplete because of mutations in genes for structural subunits of the enzyme SURF1 is significantly over-expressed. This is evident in Rho0 fibroblasts which are missing mtDNA and hence cannot synthesize subunits I, II and III of cytochrome c oxidase....
Company:MitoScience LLC

Rat Anti-Vitamin D Receptor Monoclonal Antibody, Unconjugated, Clone 9A7 from ABR-Affinity BioReagents

Description:...ans while the VDRs of mammalian species appear as single bands within the 52-55 kDa range. Immunohistochemical staining of VDR in cultured human skin fibroblasts with MA1-710 results in strong nuclear staining. MA1-710 antigen is partially purified chicken intestinal cytoplasmic 1,25-(OH)2D3 receptor prote...
Company:ABR-Affinity BioReagents

RCF (R306-05) from European Collection of Cell Cultures (ECACC)

Description:... Rat Cardiac fibroblasts (RCF) (>500,000 cells)...
Company:European Collection of Cell Cultures (ECACC)

RLF (R506-05) from European Collection of Cell Cultures (ECACC)

Description:... Rat Lung fibroblasts (RLF) (>500,000 cells)...
Company:European Collection of Cell Cultures (ECACC)
Fibroblasts in Biological Definition

Cartilage

...er that lines most types of cartilage. There are two distinct layers, an outer fibrous layer and inner chondrogenic layer. The fibrous layer contains fibroblasts which can produce collagen fibers while the inner layer contains undifferentiated or osteogenic cells capable of forming chondrocytes. If cartilage i...

Collagen

... bone . Type II collagen - Articular cartilage Type III collagen - This is the collagen of granulation tissue , and is produced quickly by young fibroblasts before the tougher type I collagen is synthesised. Type IV collagen - Basal lamina Type V collagen - most interstitial tissue, assoc. with typ...

Intermediate filament

...a keratin filament. Type III IFs Desmin IFs are structural components of the sarcomeres in muscle cells. Vimentin IFs can be found in fibroblasts and endothelial cells , they support the cell membrane and keep some organelles in a fixed place within the cytoplasm . Peripherin found in...

Skin

...n the hair papilla and epidermis, can contract, resulting in the hair fibre pulled upright and consequentially goose bumps . The main cell types are fibroblasts , adipocytes (fat storage) and macrophages . Sebaceous glands are exocrine glands which produce sebum , a mixture of lipids and waxy substances...
Fibroblasts in Biological Dictionary

Somatic hypermutation

... ... Somatic hypermutation , gene conversion and class-switch recombination are ... is sufficient to generate somatic hypermutation in fibroblasts cells (Science ... Somatic hypermutation of immunoglobulin variable genes, which increases antibody ... KlinmanNR (2001) Decreased frequenc...

Phagemid

...Vectors " Cloning Vectors " Viral Cloning Vectors " Phagemid Cloning Vectors ... Generation of Induced Pluripotent Stem Cells by Reprogramming Human fibroblasts ... phagemid DNA can be packaged into the coat of a ... The antibody fragments are cloned into the phagemid ... A variety of different metho...

Microfilament

...its. ... Retrieved from "http://en.wikipedia.org /wiki/ Microfilament " ... Microfilament Actin cytoskeleton of mouse embryo fibroblasts , stained with Fluorescein isothiocyanate - phalloidin Microfilaments (or actin filaments microfilament n. Any of the minute fibers located thr...

Aponeurosis

...anchors a muscle or connects it with the part that the muscle moves. The aponeurosis is composed of dense fibrous connective tissue containing fibroblasts (collagen-secreting spindle-shaped cells) and bundles of collagenous fibres in ordered arrays. Aponeuroses are structurally similar to tendons and.....
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(Date:7/11/2014)... July 11, 2014 Yisrayl Hawkins, Pastor and ... a letter pleading to let the children from other nations, ... allowed to come. Yisrayl says President Barack Obama is fighting ... the United States, and he wants to help him. ... from Guatemala, Honduras and El Salvador being treated as if ...
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Breaking Medicine News(10 mins):Health News:Yisrayl Hawkins Backs Barack Obama’s Pleas to Let the Children Come to the U.S. in New Letter 2Health News:Yisrayl Hawkins Backs Barack Obama’s Pleas to Let the Children Come to the U.S. in New Letter 3Health News:Netmail Heads to Washington, D.C. to Demonstrate New Release of Netmail 5.3 at WPC 2014 July 13-17, 2014 2Health News:Netmail Heads to Washington, D.C. to Demonstrate New Release of Netmail 5.3 at WPC 2014 July 13-17, 2014 3Health News:New Trial Delivers Chemotherapy to Brain Tumor Through Artery in Leg 2Health News:New Trial Delivers Chemotherapy to Brain Tumor Through Artery in Leg 3Health News:Paul McCartney Tickets for San Diego: Ticketability.com Announces Discounted Tickets for McCartney’s Tour Stop at Petco Park on September 28 2Health News:Portable Communication Systems Market Projected to Reach $39.52 Billion by 2019 - New Report by MarketsandMarkets 2Health News:Portable Communication Systems Market Projected to Reach $39.52 Billion by 2019 - New Report by MarketsandMarkets 3Health News:Portable Communication Systems Market Projected to Reach $39.52 Billion by 2019 - New Report by MarketsandMarkets 4
(Date:7/10/2014)... This news release is available in German . ... scientists, including researchers from DESY, has caught a central step ... led by Prof. Petra Fromme from Arizona State University used ... Accelerator Laboratory SLAC to record still frames of a molecular ... and oxygen, a process that maintains the oxygen in earth,s ...
(Date:7/10/2014)... While careful management has helped stabilize or even ... parts of Europe, the situation in the Mediterranean ... a new report evaluating nine fish species reported ... on July 10, scientists call for stringent ... fisheries regulations, and advanced management plans in Mediterranean ...
(Date:7/10/2014)... of overfishing in the English Channel has resulted in ... and left fishermen ,scraping the barrel, for increasing amounts ... cod, haddock and many other species at the head ... many removed from the area completely., These are some ... biologists at Plymouth University, in association with international non-profit ...
Breaking Biology News(10 mins):Scientists watch photosynthesis in action 2Scientists watch photosynthesis in action 3Mediterranean fish stocks show steady decline 2Overfishing in the English Channel leaves fisherman scraping the bottom of the barrel 2Overfishing in the English Channel leaves fisherman scraping the bottom of the barrel 3
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