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Fibrinogen in Medical News

CSL Behring Receives FDA Approval of RiaSTAP(TM), First and Only Approved Treatment of Acute Bleeding Episodes in Patients with Congenital Fibrinogen Deficiency

KING OF PRUSSIA, Pa., Jan. 16 /PRNewswire/ -- CSL Behring announced today that the U.S. Food and Drug Administration (FDA) has granted marketing approval for RiaSTAP(TM), the first and only treatment of acute bleeding episodes in patients with congenital fibrinogen deficiency, including afibrino...

AMDL Inc. Introduces New Brand Name for Its DR-70 (FDP) In Vitro Diagnostic Cancer Test

...s to effectively monitor and/or detect solid tumor cancers by measuring the accumulation of specific breakdown products in the blood called Fibrin and fibrinogen Degradation Products (FDP). The product is researched, developed and manufactured in AMDL's Tustin, California-based facilities and sold to 3rd party...

AMDL, Inc. Enters Into Distribution Agreements With GenWay Biotech, Inc. to Advance Commercialization of the DR-70 (FDP) Cancer Test in the US and Canada

...effectively monitor and/or detect certain types of cancers by measuring the accumulation of specific breakdown products in the blood called Fibrin and fibrinogen Degradation Products (FDP). FDP levels rise dramatically with the progression of cancer. DR-70 can be used as a simple, non-invasive blood test to m...

NORD to Honor Rare Disease Pioneers

... CSL Behring, for developing and bringing to market RiaSTAP(TM), the first and only treatment for acute bleeding episodes in patients with congenital fibrinogen deficiency, an extremely rare, potentially life-threatening bleeding disorder Eisai Inc., for bringing to the patient community Banzel(TM), a ...

Frost & Sullivan Commends Nycomed for Excellence in Product Differentiation Innovation

...Sil combines the bioactive mechanism of action of human coagulation factors fibrinogen and thrombin with a collagen patch for mechanical support." TachoSil e...e of bovine diseases since it contains only the coagulation factors - human fibrinogen and human thrombin." TachoSil has been registering high growth rates o...

Final Patient Completes Treatment In Boehringer Ingelheim's RE-LY(R) Study, The Largest Atrial Fibrillation Outcomes Trial To Date

...cking the activity of thrombin (both free and clot-bound), the central enzyme in the process responsible for clot (thrombus) formation - conversion of fibrinogen to fibrin. Dabigatran etexilate is not approved by the FDA. Dabigatran etexilate is approved as Pradaxa(R) in over 28 countries for the primary ...

Simple Test Helps Predict Heart Attack Risk

...ree conditions: an abnormal ABI or elevated plasma fibrinogen or elevated plasma C-reactive protein (CRP). "Even...ly perform better in terms of risk prediction than fibrinogen or C-reactive protein because it may be more speci...ther tests are needed. Elevated results for plasma fibrinogen and plasma C-reactive protein, laboratory-based te...

Haemacure Restructures - Seeks Financing or Sale of the Company

...ned manufacturing facility in Sarasota, Florida for the production of fibrinogen and thrombin; - intellectual property allowing for low-cost and high-yield production of fibrinogen and thrombin; - an open IND with the U.S. Food and Drug Administration ...

Pine bark reduces inflammatory marker CRP in osteoarthritis

...o group a marginal lowered CRP level was detected. Other blood parameters indicative of acute inflammation likewise decreased with Pycnogenol, such as fibrinogen (lowered 37.1 %) and reactive oxygen species (lowered by 29.9 %). "The decrease of systemic inflammatory markers, particularly CRP, suggests Pycno...

Bad Bosses Are Hard on the Heart

...king and delegating authority. For the study, Nyberg's team collected data on more than 3,100 Swedish men who participated in the Work, Lipids, and fibrinogen Stockholm study. The men, 19 to 70 years of age, had their hearts checked at work between 1992 and 1995. The researchers then matched these men with h...
Fibrinogen in Medical Technology

CSL Behring Receives Orphan-Drug Exclusivity for RiaSTAP(TM), First and Only Approved Treatment of Acute Bleeding Episodes in Patients with Congenital Fibrinogen Deficiency

KING OF PRUSSIA, Pa., March 11 /PRNewswire/ -- CSL Behring has been informed by the U.S. Food and Drug Administration (FDA) that because RiaSTAP(TM) is the first FDA-approved treatment of acute bleeding episodes in patients with congenital fibrinogen deficiency, the company is entitled to seven ye...

ProFibrix Steps up Recombinant Fibrinogen Program With PER.C6(R) License From Crucell

LEIDEN, The Netherlands, January 13 /PRNewswire/ -- ProFibrix B.V., today announced that it has concluded a commercial license agreement with Crucell N.V. (Euronext, NASDAQ: CRXL ; Swiss Exchange: CRX) for PER.C6(R), a unique human protein production platform. The PER.C6(R) platform allows P...

ProFibrix Initiates Phase II Clinical Trial of its Lead Topical Hemostat Product Fibrocaps(TM)

...s, with a subsidiary in Seattle, WA. The company leverages its expertise in fibrinogen technology to develop and market innovative products for the hemostasis and regenerative medicine markets. Human fibrinogen plays a pivotal role in blood clotting and tissue healing. ProFibrix is led...

HEALTHPOINT-Sponsored Venous Leg Ulcer Clinical Trial Enrolls First Subject for Second Phase II Study

...dysfunction. About HP802-247 HP802-247 consists of two components that are sprayed sequentially on the wound bed at the time of treatment: a fibrinogen solution and a cell preparation containing a mixture of growth arrested, living, allogeneic epidermal keratinocytes and dermal fibroblasts. Based on ...

Arena Pharmaceuticals Announces Lorcaserin Data Demonstrating Highly Significant Categorical and Absolute Weight Loss and Improvements in Secondary Endpoints Associated with Cardiovascular Risk

...mic Parameters: fasting glucose, fasting insulin and insulin resistance Inflammatory Markers of Cardiovascular Risk: high-sensitivity CRP and fibrinogen Quality of Life, as assessed by the Impact of Weight Questionnaire - Lite, also improved to a significantly greater extent in th...

Healthpoint Initiates Phase II, Dose-Finding Study to Evaluate Effectiveness of a Unique Cell Based Therapy in Venous Leg Ulcers

...and Europe." About HP802-247 HP802-247 consists of two components that are sprayed sequentially on the wound bed at the time of treatment: a fibrinogen solution and a cell preparation containing a mixture of growth arrested, living, allogeneic epidermal keratinocytes and dermal fibroblasts. Base...

New Study Using Combination of Bioengineered Skin and Stem Cells Shows Promise in Treatment of Non-Healing Wounds

...es advantage of the immediate polymerization, or 'gluing,' of stem cells in fibrinogen when mixed with thrombin," said Dr. Falanga. "Both fibrinogen and thrombin are naturally occurring substances in blood which, when mixed ...

Analysis of Earlier European Stroke Trial Supports Treatment Regimen for Viprinex(TM) in Current International Phase 3 Clinical Trials

...rrhages were more likely to have had prolonged low fibrinogen blood levels, to have received higher doses of anc...the drug over five to seven days, which kept blood fibrinogen levels low for too long," said David Levy, Vice Pr...ee-hour infusion which has been designed to reduce fibrinogen levels quickly, while also avoiding prolonged low...

Neurobiological Technologies, Inc. Presents Dosing Rationale for Viprinex(TM) (ancrod) at the European Stroke Conference

...ed in blood clotting and blood viscosity. Elevated fibrinogen levels are a risk factor for stroke and may be ass...isability. Prior studies with Viprinex that target fibrinogen have shown a benefit from this approach. "The pr...le, three-hour intravenous dose designed to reduce fibrinogen levels quickly, while avoiding the prolonged low...

Nostrum Announces the Successful Completion of Early Proof-of-Concept Study for its Novel Clot Busting Therapeutic Protein

...hinning and severe bleeding due to a significant degree of spontaneous plasminogen activation even in the absence of Fibrin. Moreover, SMRX11 protects fibrinogen levels in the blood, while dissolving the clot, and hence further lowering the risk of bleeding. Nostrum recently successfully completed a proof-of-...
Fibrinogen in Medical Products

STA FIBRINOGEN 5

Description: Quantitative determination of Fibrinogen by STA Analyzers (Clauss Method). Freeze-dried human thrombin (~100NIH units/mL) with heparin inhibitor and calcium....
Company:Diagnostica Stago, Inc.

STA DEFICIENT II

Description:... Substrate Plasma for Factor II Assay by STA© Analyzers. Freeze-dried human serum and absorbed bovine plasma, the latter providing factor V and fibrinogen to the test system....
Company:Diagnostica Stago, Inc.

FIBRI-PREST AUTOMATE 2

Description:... Quantitative determination of fibrinogen (Clauss Method). Freeze-dried human thrombin (~100NIH units/mL) with heparin inhibitor and calcium....
Company:Diagnostica Stago, Inc.

ELECTRA 1400C Coagulation System

Description:...o achieve low daily operational costs with extended walkaway capabilities. This system includes automated primary tube sampling and performs APTT, PT, fibrinogen and factor assays in a single setup. It also has an integrated barcode reader and automatic preparation of reference curves and patient sample dilutio...
Company:Beckman Coulter, Inc.

Fibrinogen Control

Description:... The K-ASSAY fibrinogen Control is an assayed quality control material intended for use in monitoring the accuracy and precision of the quantitative determination of fibrinog...
Company:Kamiya Biomedical Company

Pastorex® Staph Plus Kit

Description:...antigens and capsular antigens in culture media isolates. Pastorex® Staph Plus is a rapid agglutination test for the simultaneous detection of the fibrinogen affinity (clumping factor), protein A and capsular polysaccharides of Staphylococcus aureus. The test is based on a latex particle agglutination reac...
Company:Bio-Rad Laboratories

VerifyNow IIb/IIIa Assay

Description:...upon the ability of activated platelets to bind to fibrinogen coated beads. The detection well of the VerifyNow ...n of the GP IIb/IIIa receptor to a form that binds fibrinogen (Iso-TRAP). Additionally, the detection well also ...tes are blocked by the drug and cannot bind to the fibrinogen coated beads. In this instance, there will be mini...
Company:Accumetrics

TISSEEL VH Fibrin Sealant

Description:... TISSEEL VH Fibrin Sealant has been shown to be a highly effective adjunct in surgical repair. Containing uniform, reproducible concentrations of fibrinogen and thrombin, TISSEEL VH Fibrin Sealant simulates the final stage of the coagulation cascade to produce a biocompatible fibrin matrix clot that firmly...
Company:Baxter Healthcare

FLOSEAL

Features:...utes median time Clinically proven 97% effective Can be used on brisk or profuse arterial bleeding Does not require any clotting factors except fibrinogen Saves operating time / costs Mixes in 2 minutes Ss resorbed by the body within 68 weeks ...
Company:Baxter Healthcare

ACL 1000 Coagulation Analyzer

Features:... for operator safety Bar code capability to reduce manual input Proven technology to provide accurate results 110 throughput per hour for PT and fibrinogen Minimum maintenance required...
Company:Beckman Coulter, Inc.

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Fibrinogen in Medical Definition

Proteopathy

...reditary amyloidosis Gelsolin Lysozyme amyloidosis Lysozyme fibrinogen amyloidosis fibrinogen Dialysis amyloidosis β2-microglobulin Inclusion body myopathy...
Fibrinogen in Medical Dictionary

Fibrinogen

Fibrin is made from fibrinogen , a soluble plasma glycoprotein that is synthesised by the liver. ... In patients with fibrinogen deficiency, the correction of ... Explains how fibrinogen is used; when fibrinogen is used; what the results of fibrinogen might mean ... Fibrinogen ...

Total protein

...rom the VA National Hepatitis C Program. Note that the total protein (as measured by refractometer) provided with the ... The contribution of fibrinogen to total protein content in plasma compared to serum. ... Total protein Western blots for proteomics, gene discovery, & protein ...

Temporom

...erminology,medical terms,medical ... root, cracked tooth syndrome, temporom andibular disease, impaction, eruption, ... Histamine release and fibrinogen adsorption mediate acute ... prostheses [18], temporom andibular [19] and other join t. implants [20] ... Section 1 combines military websites...

Clot

... blood cells, and platelets entrapped in a fibrin clot n. A thick, viscous, or coagulated mass or lump, as of blood. ... Clot retraction and fibrinogen content of the blood sample are also influential. ... Read about blood clot in the legs (deep vein thrombosis, DVT) caused by ... occur i...
Fibrinogen in Biological News

GenWay Biotech obtains exclusive rights to AMDL's DR-70 cancer test in US and Canada

.... However, a growing body of data reveals that the test is effective as a general cancer screen as well. The DR-70 ELISA assay quantifies Fibrin and fibrinogen Degradation Products (FDP) in the blood, which are elevated in the presence of a malignant tumor and increase as the malignancy grows. International ...

Simple test helps predict heart attack risk

...ree conditions: an abnormal ABI or elevated plasma fibrinogen or elevated plasma C-reactive protein (CRP). "Even...ly perform better in terms of risk prediction than fibrinogen or C-reactive protein because it may be more speci...ther tests are needed. Elevated results for plasma fibrinogen and plasma C-reactive protein, laboratory-based te...

A novel target for therapeutics against Staph infection

...vered how a bacterial pathogen interacts with the blood coagulation protein fibrinogen to cause methicillin-resistant Staphylococcus aureus (MRSA) infections, a...f S. aureus. The group found that ClfA binds to the blood-clotting protein fibrinogen (Fg) at a site that is also responsible for inducing platelet activation an...

Indicators for risk of heart disease are higher in passive smokers

...cotinine groups had significantly higher levels of fibrinogen and homocysteine than the 'no detectable' group, with fibrinogen levels estimated at 9?0 milligrams per decilitre h...igher. Dr Venn said: "The increased levels of fibrinogen and homocysteine seen in relation to second-hand s...

Exploring the molecular origin of blood clot flexibility

...the three, tightly twisted rod-like regions within fibrinogen molecules, called alpha-helical coiled-coils. The ...sured this change by pulling engineered strands of fibrinogen molecules using an atomic force microscope. This a...'t known before that the coiled coil region of the fibrinogen molecule would be the part to unfold under the str...

Inhibiting blood to save the brain

...elin sheath is associated with the accumulation of fibrinogen deposits in the brain of human MS patients. In this study, Akassoglou and colleagues showed that fibrinogen is not merely associated with the damage in MS, but an active participant. fibrinogen activates macrophage cells in the brain called mic...
Fibrinogen in Biological Technology

Atherotech to Exhibit its VAP(R) Cholesterol Test at Internal Medicine 2009 in Philadelphia

... available immediately and also include homocysteine, creatinine, creatine kinase (CK), HbA1c, TSH, ALT, AST, urea nitrogen (BUN), glucose, vitamin D, fibrinogen and insulin. The tests can be ordered individually, or bundled as part of a custom risk profile that may also include the VAP Test. Atherotech r...

Atherotech Unveils New Cardiometabolic Test Panels

... available immediately and also include homocysteine, creatinine, creatine kinase (CK), HbA1c, TSH, ALT, AST, urea nitrogen (BUN), glucose, vitamin D, fibrinogen and insulin. The tests can be ordered individually, or bundled as part of a custom risk profile that may also include the VAP Test. The VAP Test...
Fibrinogen in Biological Dictionary

Serum

... Blood serum is blood plasma without fibrinogen or the other clotting factors (i. ... Transferrin saturation = Serum iron / Total iron-binding capacity ... Serum may refer to: The serum i...

Dimer

...> Clinical Laboratory News > 2009 > April ... Thrombin converts fibrinogen into soluble fibrin monomer. ... Thrombin also activates factor XIII, which... C-Reactive Protein as Cardiac Risk Factor. Erythrocyte Sedimentation Rate. fibrinogen ... Used in conjunction with non-invasive studies. Reduces the need for ......
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