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Ferritin in Medical News

Ruben Studdard, American Idol Winner and R&B Pop Star, Spreads the Word about Sickle Cell Disease and the Dangers of Iron Overload

... and Spanish) -- Free, on-site iron overload screenings (serum ferritin tests) for eligible patients -- Declaration of...s at risk for iron overload due to blood transfusions. A serum ferritin level of over 1,000 mcg/L means that a person may be at risk f...

Early treatment of systemic onset JIA with anakinra restores the IL-18 response

...after 3 days. A rapid decrease in ESR (erythrocyte sediment rate; an indication of inflammation), CRP (C reactive protein; a marker for inflammation), ferritin (a test of iron stores in the body) and sIL-2R (soluble interleukin 2 receptor) was observed. No differences of IL-1alpha, IL-1beta and IL-33 were obs...

DaVita Study Demonstrates Clinical Application of Sysmex Reticulocyte Hemoglobin Equivalent (RET-He) Parameter

...arameters studied were Hb, Hct, reticulocyte Hb (RET H e or CHr), TSAT and ferritin levels. The purpose of the DaVita(R) study was to evaluate the clinica...H e or CHr) were useful analytes to guide ESA and IV iron therapy, whereas ferritin and TSAT were not reliable guides for month to month dose adjustments for E...

Retrospective Analysis Finds Treatment of Cancer Chemotherapy Patients With Epoetin Alfa Associated With Lower Drug Cost Than Darbepoetin Alfa

...valuated. Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or functional iron deficiency may develop and all patients will eventually requi...

Hyperferritinemia is another surrogate marker of advanced liver disease

...A study in Italy has investigated the link between ferritin and steatosis in a non-obese cohort of non-alcohol...c patients. In southern European populations, high ferritin levels, after exclusion of diagnosis of HH, repres...onic liver disease characterized by elevated serum ferritin levels, of varying etiology, excluding hemochromat...

Study finds iron levels not predictive of survival for form of blood cancer

...usion at diagnosis were stronger predictors for patient survival than serum ferritin level (a protein that stores iron), which is often used as a proxy for iron...ood. "Although iron chelation therapy in PMF would probably lower serum ferritin level in such patients, its value in terms of meaningful health outcomes re...

Blood protein may hold key to stopping tumor growth in cancer patients

...rowth. Researchers found that a protein called ferritin binds to and cripples the ability of another blood...is that if they can somehow prevent the binding of ferritin and HKa, it will allow HKa to prevent new blood ve...erefore possible that by increasing the binding of ferritin to HKa, one could increase the rate at which a ser...

Exjade(R) Benefits Chronically Transfused Patients by Significantly Reducing Toxic Iron That Can Damage Key Organs, According to Landmark Trial

...olled in the study showed that Exjade significantly reduced levels of serum ferritin (SF), a key measure of iron in the body, by 253.0 ng/mL from baseline (P=0....ntake, with subsequent dose titration at 3-monthly intervals based on serum ferritin (SF) trends. With 1,744 patients, this trial is the largest ever conducted ...

Researchers to Present Additional Data on Soliris(R) (eculizumab) for the Treatment of PNH at the ASH Annual Meeting

...r. Richard Kelly, et al. Abstract: http://ash.confex.com/ash/2008/webprogram/Paper11166.html -- "Effect of Reducing Intravascular Hemolysis on ferritin Homeostasis in Eculizumab Treated Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients," Dr. Alexander Roeth, et al. Abstract: http://ash.co...

Low Iron Levels Cut Cancer Risk in Men With PAD

...A, leading to cancer development. "Findings from this study support the hypothesis that ambient levels of body iron stores represented by the serum ferritin level are associated with cancer risk and that lowering iron levels reduces cancer risk," the authors wrote. An accompanying editorial in the journ...
Ferritin in Medical Technology

Siemens Healthcare Diagnostics Launches B12, Folate, and Ferritin Tests on Its Dimension vista Intelligent Lab System

Anemia test menu expanded through use of advanced LOCI(R) chemiluminescence technology DEERFIELD, Ill., Jan. 16 /PRNewswire-FirstCall/ -- Siemens Healthcare Diagnostics, today announced that it has launched the LOCI(R) Folate, LOCI(R) B12, and LOCI(R) Ferritin tests...

Observational Study Finds Changes in Medicare Reimbursement for Erythropoiesis-Stimulating Agents Associated With Increased Need for Blood Transfusion

...valuated. Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or functional iron deficiency may develop and all patients will eventually requi...

Data From Investigational Use of PROCRIT(R) (Epoetin alfa) Presented at American Society of Nephrology Annual Meeting

...d. -- Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or functional iron deficiency may develop and all patients will eventu...

Observational Studies Assess the Potential Impact of Limiting Erythropoiesis-Stimulating Agent Availability on Frequency of Blood Transfusions

...ated. -- Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or functional iron deficiency may develop and all patients will eventua...

New Data Highlighting Possible Impact of ESA Reimbursement Policies on Patient Care, Nation's Blood Supply, to be Presented at American Society of Clinical Oncology (ASCO) Annual Meeting

...ated. -- Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or functional iron deficiency may develop and all patients will eventua...

Data From Ortho Biotech-Sponsored Studies to be Presented at National Kidney Foundation 2008 Spring Clinical Meetings

...ated. -- Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or functional iron deficiency may develop and all patients will eventua...

Ortho Biotech Statement on U.S. Food and Drug Administration Oncologic Drugs Advisory Committee Vote

...ated. -- Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or functional iron deficiency may develop and all patients will eventual...

Totality of Available Data Reaffirms PROCRIT(R) (Epoetin alfa) Is Safe and Effective When Used Appropriately as Labeled to Treat Chemotherapy-Induced Anemia

...ated. -- Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or functional iron deficiency may develop and all patients will eventua...

Observational Data Show Transfusion Patterns in Chemotherapy-Induced Anemia Patients Receiving Erythropoiesis-Stimulating Agents

...ated. -- Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or functional iron deficiency may develop and all patients will eventua...

Research Identifies Need for Improved Understanding of Sickle Cell Disease in Adulthood

...in comparison to normal values. In addition, after one year of treatment, the deferiprone-deferoxamine group showed greater efficacy in terms of serum ferritin level reduction than the deferoxiamine-only arm of a previous randomized clinical trial in which a comparable cohort of patients were studied. -- ...
Ferritin in Medical Products

Quantimune Ferritin IRMA

Description: Bio-Rad isotopic anemia assays feature standardized protocols and minimal pipetting steps for greater efficiency. Clear information about the processes involved in isotopic testing and the benefit to your laboratory is available from our customer support specialists....
Company:Bio-Rad Laboratories

Human Ferritin

Description: The BioCheck Ferritin ELISA is intended for the quantitative determination of ferritin in human serum. This assay is to be used in the diagnosis of diseases affecting iron metabolism....
Company:BioCheck, Inc.

Ferritin IRMA Test

Description:... ferritin is the main storage protein for iron. The ferritin molecule consists of a protein shell (apoferritin)...line core containing iron oxide and phosphate [1]. ferritin is synthesized in the liver, spleen and numerous o...
Company:Diagnostic Systems Laboratories, Inc.

Ferritin

Description:... The DSL-10-3000 ACTIVE ferritin Enzyme-Linked Immunosorbent (ELISA) Kit provides materials for the quantitative measurement of ferritin in serum....
Company:Diagnostic Systems Laboratories, Inc.
Ferritin in Medical Dictionary

Ferritin

Ferritin is a globular protein complex consisting of 24 protein subunits and is the primary intracellular iron-storage protein in both prokaryotes and eukaryotes, keeping iron in a soluble and non-toxic form. Ferritin that is... Ferritin is found in the liver, spleen, skeletal ...

Serum iron

...st might mean Serum Iron . Also ... stage, ferritin will be low, but serum iron and TIBC are usua...ron is in your blood. ... Iron and serum ferritin tests and their significance in understanding ha...oss ... An explanation of what iron and serum ferritin test results mean for hair loss ... Serum ...
Ferritin in Biological News

Scientists discover novel way to remove iron from ferritin

November 2, 2007 - Oakland, CA -- A new study led by Children's Hospital Oakland Research Institute senior scientist, Elizabeth Theil, Ph.D., is the first to suggest that a small protein or heptapeptide (seven amino acids wrapped into one unit) could be used to accelerate the removal of iron from ...

Penn researchers demonstrate a new model for drug discovery with a fluorescent anesthetic

...A by other anesthetics attenuates the fluorescence signal and allows determination of anesthetic affinity, that is, the drugs that bind tightly to the ferritin anesthetic site. In this way, 1-AMA fluorescence could be used to discover new anesthetics. This provides a unique fluorescence assay for compound s...

Plant studies reveal how, where seeds store iron

...ng seed crops such as grains and beans with increased content of this important nutrient." The findings reveal how essential it is to look beyond ferritin to understand how iron is stored by plants. The researchers say the stored iron in the vacuole is a key source of iron for developing seedlings. Seedl...

Plant studies reveal how, where seeds store iron

...ng seed crops such as grains and beans with increased content of this important nutrient." The findings reveal how essential it is to look beyond ferritin to understand how iron is stored by plants. The researchers say the stored iron in the vacuole is a key source of iron for developing seedlings. Seedl...

Novel live reporting system to track cells

...rtment, developed the capacity of the iron-bearing ferritin molecule to serve as a sort of gene "spy" by makin...tic modifications to cells. This approach rendered ferritin sensitive to tetracycline (TET), a common antibiotic, so that when TET is present, the ferritin is "off" and when TET is absent,...
Ferritin in Biological Technology

Centocor Ortho Biotech Data to be Presented at American Society of Clinical Oncology (ASCO) Annual Meeting

...valuated. Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or functional iron deficiency may develop and all patients will eventually requi...

Beckman Coulter Announces Fourth Quarter and Full Year 2008 Results; Earnings Outlook Achieved on Strong Fundamentals

...a wide range of test mix and volume requirements. Received FDA clearance for the Access(R) Soluble Transferrin Receptor assay and the sTfR/log ferritin index as aids in the diagnosis of iron deficiency anemia and anemia of chronic disease. Launched the SPRI-TE(TM) Nucleic Acid Extractor for si...

Soliris(R) Reduced Measures of Thrombosis and Inflammation, and Decreased Indicators of Pulmonary Hypertension, in Studies of Patients with PNH

...ard dose. For details, visit: http://ash.confex.com/ash/2008/webprogram/Paper8331.html . A poster titled "Reducing Intravascular Hemolysis on ferritin Homeostasis in Eculizumab Treated Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients" was presented yesterday at the ASH annual meeting by Alexander R...

New Study by BioTrends Highlights Anemia Practice Patterns According to Anemia Managers in Both Dialysis Units and CKD Clinics/Offices

...n in the next three months, and over one-third report changing their IV iron protocol in the past three months -- most often allowing higher levels of ferritin before holding IV iron and making more effort to keep patients on maintenance therapy (by extending dosing frequency, for example) instead of disconti...

Ortho Biotech Modifies Prescribing Information for PROCRIT(R) (Epoetin alfa)

...ated. -- Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or functional iron deficiency may develop and all patients will eventua...

Ortho Biotech Statement On JAMA Publication Regarding Erythropoiesis-Stimulating Agents

...ated. -- Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or functional iron deficiency may develop and all patients will eventual...

Ortho Biotech Modifies Prescribing Information for PROCRIT(R) (Epoetin alfa) Label Reflects Recommendations from Recent FDA Advisory Committee Meetings

...ated. * Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or functional iron deficiency may develop and all patients will eventua...

Ortho Biotech Supports FDA Advisory Committees' Recommendations on Use of ESAs in Chronic Renal Failure Patients

...ated. -- Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or functional iron deficiency may develop and all patients will eventua...
Ferritin in Biological Dictionary

Transferrin receptor

...ivity (see key) ... Transferrin Receptor antibody. ICC, WB. Rabbit polyclonal ... The Usefulness of the Serum Transferrin Receptor to Serum ferritin Ratio for ... transferrin , human protein, human serum, iron binding, receptor , transferrin ... ( A recently described second transferrin...
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