Inflammatory molecules released by pollen trigger allergies
How do pollen particles provoke allergic reactions? A new study in the February 21 issue of The Journal of Experimental Medicine puts some of the blame on bioactive molecules that are released from pollen. These molecules bind to immune cells and cause them to launch a typical allergy-promoting immune response. Pollen from plants exposed to air pollutants produce more of these allergy-provoking c...How an AIDS-Related Cancer Unleashes Inflammation
Although new HIV treatments have drastically reduced the incidence of Kaposi's sarcoma in developed countries, it remains a health threat in many developing countries. Now, researchers have discovered one way that Kaposi's sarcoma ?a cancer-like viral disease traditionally associated with AIDS ?triggers severe inflammation. Don Ganem, a Howard Hughes Medical Institute (HHMI) investigator,...Researchers report new pro-inflammatory role for anti-inflammatory enzyme
Part of the immune system's pro-inflammatory response to bacterial invasion is to increase nitric oxide levels with an enzyme called inducible nitric oxide synthase. In a study published in the Journal of Biological Chemistry, scientists report that the predominantly anti-inflammatory enzyme, endothelial nitric oxide synthase, is also involved in nitric oxide production in response to infection....B cells are required for development of epithelial cancer associated with chronic inflammation
Chronic inflammation is linked to the development of certain types of cancer, but mechanisms mediating inflammation during premalignancy are not well understood. A new research study published in the May issue of Cancer Cell identifies B lymphocytes as important regulators of premalignancy associated with chronic inflammation. The results suggest that drugs targeted against B lymphocytes or recru...Corning Proculture Spinner Flask,15L,Vertical S/Arm, No. Of S/A 4,Cent Neck 100mm from Sigma-Aldrich
Description:This CLS number is a new product number, created to easily match Cornings product number. If showing no availability yet, please order under the old Sigma-Aldrich number (Z71,487-9) or contact customer service for assistance. ID clarifier: centre neck 100 mm, No. of sidearm 4 Mfr Desig: Corning 4510-15L...FLAG Immunoprecipitation Kit from Sigma-Aldrich
Description:Sigmas FLAG Immunoprecipitation kit allows a rapid and efficient immunoprecipitation and elution of an active FLAG-tagged protein. The immunoprecipitation is performed with ANTI-FLAG-M2 affinity gel, which is a highly specific monoclonal antibody covalently attached to agarose resin. The use of affinity resin allows an efficient binding of FLAG-tagged proteins without the need for preliminary ste...Automatic Cuff Inflation Pump from IITC Life Science
Description:The IITC Model 20-NW cuff pump is a dedicated cuff pump for small animal noninvasive blood pressure testing. This cuff pump replaces manual inflation and can be used for all IITCs indirect blood pressure test systems for mouse and rat; from single up to multi-channel systems are available. The IITC Model 20-NW cuff pump has adjustable cut-off pressure in 50 mmHg increments, adjustable deflation r...1 Liter Flask Clip from Thermo Scientific
Description:Heavy duty stainless-steel shaker flask clips, purpose-designed to firmly retain glassware, even at high speeds. All clips are equipped with a top retainer spring; larger clips (over 1L.) also include a bottom retainer spring, and silicon tubing spring covers, to prevent scratching of expensive glassware. Clips include the required mounting screws. Microplate clip is a one-piece, stainless...250/300ml Flask Clip from Thermo Scientific
Description:Heavy duty stainless-steel shaker flask clips, purpose-designed to firmly retain glassware, even at high speeds. All clips are equipped with a top retainer spring; larger clips (over 1L.) also include a bottom retainer spring, and silicon tubing spring covers, to prevent scratching of expensive glassware. Clips include the required mounting screws. Microplate clip is a one-piece, stainless...Simple, Sensitive, and Rapid Detection of FLAG -Tagged Fusion Proteins
-TaggedFusion Proteins Qiyi Xie Quinn Lu Tanya Hosfield Peter Pingerelli Weiping Yang Stratagene...High-Level Protein Expression, One-Column Purification, and FLAG Epitope Tagging in E. coli
Epitope Tagging in E. coli Katherine Felts Denise Wyborski John Bauer PeterVaillancourt Stratagene LIC cloning kit...Structural Determination of Flavonoids Using MSn
Jack Cunniff, Philip Tiller, Michael Harvey, and Adrian Land, Thermo Finnigan The data presented here can be acquired using the Thermo Finnigan LCQ Series of ion trap mass spectrometers....Purification of Recombinant Flavonone 3beta-Hydroxylase Using Bio-Scale CHT5-1 Hydroxyapatite Column
Flavanone 3b-hydroxylase (FHT), a typical 2-oxoglutaratedependent dioxygenase, catalyzes the 3b-hydroxylation of 2S-flavanones to 2R,3R-dihydroflavonols which are intermediates in the biosynthesis of flavanoids, catechins, proanthocyanidins, and anthocyanidins in plants. To understand the complex reaction mechanism,...Evaluation of FlashPlate in a Helicase Assay
P]-γ-ATP. The oligos wer...Safeguarding anti-inflammatory users from ulcers
Abolishing a common stomach-dwelling bacterium makes the long-term use of anti-inflammatory drugs safer. Many people would benefit from chronic usage// of non-steroidal anti-inflammatory drugs (NSAIDs) like aspirin and diclofenac. Not only do these drugs relieve the symptoms of arthritis, they also protect against heart attack, stroke and maybe even Alzheimer's disease. But the NSAIDs h...Vannas straight capsulotomy flat handle scissors
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Description:...Array BioPharma Reports New Clinical Data on Its Anti-Inflammatory Drugs
BOULDER, Colo.--(BUSINESS WIRE)--Jun 20, 2007 - Array BioPharmaInc. (Nasdaq: ARRY) announced new Phase 1 clinical data on its MEKinhibitor, ARRY-162, and its p38 inhibitor, ARRY-797. These resultswere presented at the Annual European Congress of Rheumatology(EULAR) in Barcelona, Spain, and at the International Associationof Inflammation Societies' (IAIS) 8th World Congress onInflammation in...Targeted Genetics Reports Inflammatory Arthritis Clinical Data at European Rheumatology Conference
BARCELONA, SPAIN and SEATTLE, WA -- (MARKET WIRE) -- June 14,2007 -- Targeted Genetics Corporation (NASDAQ: TGEN) today isreporting data from the dose escalation arm of the ongoing PhaseI/II clinical study of tgAAC94 in patients with inflammatoryarthritis. Philip J. Mease, M.D., clinical professor at theUniversity of Washington School of Medicine, chief of rheumatologyclinical research a...Nonsteroidal anti-inflammatory drugs
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