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FFPE in Medical News

Pathwork Diagnostics Launches Version of Its Tissue of Origin Test for FFPE Specimens

New Version Increases Physician Access SUNNYVALE, Calif., Jan. 13 /PRNewswire/ -- Pathwork Diagnostics, Inc., launched today an additional version of the Pathwork(R) Tissue of Origin Test that has the capability of analyzing formalin-fixed, paraffin-embedded (FFPE) tissue specimens. This mole...

Pathwork Tissue of Origin Test Validation Study Published in Journal of Clinical Oncology

...ozen tissue samples, a separate validation study performed by Pathwork with ffpe (formalin-fixed, paraffin-embedded) specimens showed similar performance. Both the frozen and ffpe versions of the test are commercially available as a service through Pathwo...
FFPE in Medical Technology

Johns Hopkins University Researchers to Clinically Assess Rosetta Genomics' miRview(TM) Squamous Assay

...n due to different side effect profiles or different levels of efficacy. Combining Rosetta Genomics' proprietary microRNA extraction technology from ffpe samples, sensitive quantification platforms, and microRNA molecular biomarkers identified by the company, Rosetta Genomics has developed a test which ...

HERmark(TM) Assay Results in Metastatic Breast Cancer Presented at the San Antonio Breast Cancer Symposium

...Rmark studies have provided data which consistently indicate that HERmark can precisely measure HER2 expression and HER2:HER2 dimer levels in clinical ffpe samples, and that those patients with higher levels of expression have significantly better clinical outcomes than those with lower levels. These data...
FFPE in Biological Technology

GenomiPhi amplification of FFPE tissue DNA for array CGH

Key words: formalin-fixed paraffin-embedded (FFPE) • GenomiPhi • whole-genome amplification (WGA) • degenerate oligonucleotideprimed PCR (DOP-PCR) • Cy3/Cy5-dCTP probe labeling • comparative genomic hybridization (CGH) • bacterial...

Optimum FFPE RNA Isolation Kit

Total RNA Isolation from Formalin Fixed Paraffin Embedded (FFPE) Tissues Phenol-free isolation of total RNA from FFPE tissues Optimized for qRT-PCR ffpe tissue is particularly important as this is the standard fixation and stora... complexes and post-translational modifications such as phosphorylation, in ffpe tumor samples and can aide cancer drug development and clinical evaluation....

Henry Ford Hospital and Rosetta Genomics to Develop MicroRNA-based Diagnostics for Brain Cancer

...omarkers, is that they do not degrade when the tumor sample is stored as an ffpe block. As ffpe blocks can be stored at room temperature, these sample types are readily av...

Genomic Analysis of Formalin-Fixed Paraffin Embedded (FFPE) Tissues through the use of Whole Genome Amplification (WGA)

...orly on samples stored in unbuffered formalin or ffpe preserved samples. This so-called formalin problem...researchers have shown that the ability to analyze ffpe derived material in applications such as microar...een successful in varying degrees when used with ffpe DNA, MSD has suffered in that it relies on a highl...

miRNeasy Mini Kit and miRNeasy 96 Kit

...ed, paraffin-embedded (FFPE) tissue sections (using the RNeasy ffpe Kit), a supplementary protocol is available at www.qiagen.com/m...y 96 Kit, RNeasy MinElute Cleanup Kit, RNeasy 96 Kit, and RNeasy ffpe Kit are intended for research use. No claim or representation is...

A Novel Process for Gene Expression Profiling of Rat and Mouse Tissues from Formalin-Fixed Paraffin-Embedded Sections Using Microarrays

...nd Paraffin-Embedding. Since the macromolecules in ffpe tissues are crosslinked, efficiently extracting an...tes efficient isolation of total cellular RNA from ffpe sections, linear amplification of transcripts from...inase K solution (Paradise Reagent System) for ffpe sections. If needed, multiple tissue sections we...

Recover High Yields of Total Nucleic Acid from Formalin-fixed, Paraffin-embedded (FFPE) Tissue

... Kit For decades, ffpe tissue has been the staple of...nd making patient diagnoses. More than 400 million ffpe tissue samples exist for canc... and RNA, including miRNA) from the same ffpe sample. Efficient protease di...

Protocol for GenomePlex Whole Genome Amplification from Formalin-Fixed Parrafin-Embedded (FFPE) tissue

... IV. Protocol for Extraction of DNA from ffpe tissue ..............................................col for GenomePlex Whole Genome Amplification from ffpe tissue ........................4 ...s is essential. However, amplifying the ffpe tissue can be a difficult task due to the damaged ...
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