Navigation Links
FAK in Biological News

When cancer cells can't let go

...rily attaching to the ECM through focal adhesions. fak spurs focal adhesions to disengage, and it is more abundant in metastatic tumors. Whether fak also regulates invadopodia was unknown. When Ch...ly sticky. The protein Src serves as FAK's helper. fak and Src work together to phosphorylate tyrosines i...

JCI online early table of contents: Jan. 19, 2009

...p?id=33216 ONCOLOGY: Role for the protein fak in breast cancer A team of researchers, led b...pathways are under development. In this study, the fak gene was found to be amplified in a substantial nu...ving a role in tumor development, mice lacking the fak gene in breast tissue were protected in a model of...

Dense tissue promotes aggressive cancers

...h the motors themselves are not present in the drilling structures. The investigators also implicated the activities of two signaling proteins called fak and p130Cas in the rigidity-induced invadopodia activity. These signaling proteins were present in an activated state in the invadopodia, suggesting t...

Leading cause of death in 'preemies' might be controlled by resetting a molecular switch

...arm in mice with NEC by interfering with production of a focal adhesion kinase (FAK) that the researchers found associated with TLR4. By shutting down fak with small interfering RNA, the TLR4 siren was silenced. Under these conditions, the researchers watched enterocytes regain the ability to migrate, a ...

Fatty spheres loaded with siRNA shrink ovarian cancer tumors in preclinical trial

... They received liposomes that contained either the fak siRNA, a control siRNA, or were empty. Some mice ...h and penetrating cells. The next step for the fak siRNA-DOPC liposome is toxicity testing. "So far ...n the future." In addition to ovarian cancer, fak is overexpressed in colon, breast, thyroid, and he...

Molecular force field helps cancer cells defend against attack

...s of tumor survival. These medicines would prevent fak from linking with the protein known as vascular en...rs. Cance and colleagues were the first to pull fak out of human tumors and to show that human cancers...ntists also have identified some protein receptors fak binds to; VEGFR-3 is the latest they've discovered...
FAK in Biological Technology

YOUR DATA: Direct Real-time RT-PCR on Sympathetic Neuron Lysates Silencing of Focal Adhesion Kinases with Silencer Validated siRNAs

...elated focal adhesion kinases fak (PTK2) and Pyk2 (PTK2B) -- in the ...ne Silencing of the Related Focal Adhesion Kinases fak and Pyk2 . HeLa cells were transfec...ecific for F ocal A dhesion K inase, fak (PTK2), or P roline-rich t yrosine k...

YOUR DATA: Direct Real-time RT-PCR on Sympathetic Neuron Lysates Silencing of Focal Adhesion Kinases with Silencer Validated siRNAs

...elated focal adhesion kinases fak (PTK2) and Pyk2 (PTK2B) -- in the ...ne Silencing of the Related Focal Adhesion Kinases fak and Pyk2 . HeLa cells were transfec...ecific for F ocal A dhesion K inase, fak (PTK2), or P roline-rich t yrosine k...

Setting up a kinase profiler with IMAP

...ontrast, a validated IMAP substrate for fak had not yet been found, so the IMAP SF ...gure 6, the initial assay with 0.07 U/mL fak (Panel A) was then repeated with 0.02 U/... Table 2. Top-Ranking fak Substrates SF...
Other Tags
(Date:10/31/2014)... Monica Williams-Murphy MD , advanced care ... the chaos that can occur for people who have ... of Americans who come into the emergency department facing ... for the moment and so are their families." She ... a catalyst for a family to get the critical ...
(Date:10/31/2014)... 31, 2014 Activz Whole-Food Nutrition ... Silver line offering natural silver healing support† in ... a century, silver has been used to support natural ... products is the most advanced version available. This latest ... chemical structure that supports the existing healing mechanisms in ...
(Date:10/31/2014)... 2014 (HealthDay News) -- Obesity increases the risk of ... Hispanic women, two new U.S. studies show. One ... overweight or obese increased the risk for estrogen receptor-negative ... "We,ve known this for a long time for white ... Hispanic women," study author Esther John, a senior research ...
(Date:10/31/2014)... engineers have invented a lab device to give cancer ... way that tumor cells spread through the body, causing ... light on precisely how tumor cells travel, the device ... , The inventors, from the university,s Whiting School of ... and images from their new system recently in the ...
(Date:10/31/2014)... Beach, Florida (PRWEB) October 31, 2014 ... or, the “Company”) today announced it has signed a ... Canada-based companies in the urban cultivation sector - Urban ... (BC Northern Lights”), and W3 Metal Inc. (“W3 Metal” ... the “Target Companies”). Pursuant to the LOI and ...
Breaking Medicine News(10 mins):Health News:This Thanksgiving or Christmas Family Gathering, Use The New App ListStuffFast to Start "The Conversation" With a Parent That Has No Plan For End-of-Life 2Health News:This Thanksgiving or Christmas Family Gathering, Use The New App ListStuffFast to Start "The Conversation" With a Parent That Has No Plan For End-of-Life 3Health News:New Collection of Nano-particle Natural Silver Products by Activz Whole-Food Nutrition 2Health News:New Collection of Nano-particle Natural Silver Products by Activz Whole-Food Nutrition 3Health News:New Collection of Nano-particle Natural Silver Products by Activz Whole-Food Nutrition 4Health News:Study Confirms Obesity-Breast Cancer Link for Blacks, Hispanics 2Health News:Viewing cancer on the move: New device yields close-up look at metastasis 2Health News:Viewing cancer on the move: New device yields close-up look at metastasis 3Health News:Urban Hydroponics Inc. Signs Definitive Agreement to Merge with Canadian Hydroponics Companies 2Health News:Urban Hydroponics Inc. Signs Definitive Agreement to Merge with Canadian Hydroponics Companies 3Health News:Urban Hydroponics Inc. Signs Definitive Agreement to Merge with Canadian Hydroponics Companies 4Health News:Urban Hydroponics Inc. Signs Definitive Agreement to Merge with Canadian Hydroponics Companies 5
(Date:10/29/2014)... ceremony held in New York City on September 19, ... American Cancer Society Professor of Genome Sciences and Medicine ... Honorary Doctor of Philosophy of Tel Aviv University, was ... Science. , In addition to her honorary degree from ... the TAU School of Medicine, and for the past ...
(Date:10/29/2014)... kind of stem cell, those referred to as ,facultative, ... is apparently nothing that differentiates these cells from the ... they retain the capacity to become stem cells again. ... an organ that hosts cells that stimulate tissue growth, ... case of a transplant. Knowledge of the underlying ...
(Date:10/29/2014)... the living world compete with members of their ... much they invest into their competitive ability. Some ... access to high-quality resources, while others seem to ... lower-quality resources that are left over for them. ... human societies seems to fluctuate considerably over time. ...
Breaking Biology News(10 mins):Geneticist and humanitarian: Prof. Mary-Claire King receives Lasker Award 2A mechanism that allows a differentiated cell to reactivate as a stem cell revealed 2Evolution of competitiveness 2Evolution of competitiveness 3
Other Contents