Bellicum Pharmaceuticals Announces Initiation of Phase I/II Clinical Trial of Novel Vaccine for Patients With Advanced Prostate Cancer

...whose disease has not progressed at the end of this acute phase will be eligible to receive booster vaccinations every eight weeks for up to one year. exploratory efficacy endpoints include prostate-specific antigen dynamics, circulating tumor cell count, antigen-specific immune response, and clinical response. ...

Radiation Plus Chemo a Good Option in Lung Cancer

... rates of the 396 patients after five years to draw their conclusions. They found no statistically significant difference in overall survival. In an exploratory analysis, the researchers found that overall survival did improve for patients who only had part of a lung removed (lobectomy) rather than an entire l...

Colon capsule endoscopy diagnoses 64 percent of total polyps detected by conventional colonoscopy

...is sense, the improvements put forward as a result of the study focus on the importance of a more thorough cleaning of the colon before initiating the exploratory test, given that, with conventional colonoscopy, the specialist can clean relatively with water some of the dirty areas found during the exploration ...

C'elle(SM) Featured on ABC Action News in Tampa Bay

...ation, among others. In 2008, the Company announced its collaboration with the National Institutes of Health (NIH), whose scientists are conducting an exploratory study of MenSCs for potential utilization in the treatment of breast cancer. This collective body of ongoing research may potentially change the types...

VIVIMIND(TM) granted certificate of free sale as food supplement in Italy - Premarket notification filed in the U.S.

... Aisen, S. H. Ferris, D. Saumier, A. Duong, D. Haine, et al. (2009). Effect of Tramiprosate in Patients with Mild-to-Moderate Alzheimer's Disease: exploratory Analyses of the MRI Sub-group of the Alphase Study. Journal of Nutrition, Health and Aging, Volume 13, Number 6/June 2009, 550-557. Certain s...

Omega-3 Fatty Acid Falls Short in Alzheimer's Trials

...ative people should be on DHA," Quinn said. "We don't know a mechanism that would account for a benefit in e4-negative people and we don't know if our exploratory analysis would be confirmed in future trials." His study, funded by the U.S. National Institute on Aging, included 402 people, average age 76, with...

Perceptive Informatics Enhances CNS and Oncology Medical Image Processing and Analysis Capabilities Through Alliance With Biospective

...ialized medical imaging process and analysis software to supplement its existing technology in support of independent reviews of imaging data for both exploratory and large-scale, multi-center studies. Experts from Perceptive Informatics will discuss these enhanced capabilities at Booth #333 in the exhibit...

New Program May Help Teens at High Risk for Depression

... Dr. Lorrin Koran, professor and chairman emeritus of the department of psychiatry at Duke University, said that he viewed the study as "an important exploratory effort to identify ways of preventing depression in adolescents." However, he added, "the results are puzzling and somewhat disappointing, in that ...

Computer modeling shows strategies to rein in epidemics need to be retooled for rural populations

... the Great Plains. Caterina Scoglio, associate professor of electrical and computer engineering, is leading an Epicenter research project called SGER: exploratory research on complex network approach to epidemic spreading in rural regions. Scoglio is working with Todd Easton, associate professor of industrial...

Strategies to Rein in Epidemics Need to be Retooled for Rural Populations, Say K-State Engineers Using Computers to Model Disease Outbreaks in Rural Areas

... the Great Plains. Caterina Scoglio, associate professor of electrical and computer engineering, is leading an Epicenter research project called SGER: exploratory research on complex network approach to epidemic spreading in rural regions. Scoglio is working with Todd Easton, associate professor of industr...

Exploratory in Medical Technology

PRA International: Participating Sponsor for Exploratory Clinical Development World in London

RALEIGH, N.C., May 12 /PRNewswire/ -- PRA International, a leading Clinical Research Organization, announces it is participating as a sponsor for Exploratory Clinical Development World (ECDW), 13-14 May 2009, in London, UK. ECDW is considered to be Europe's largest and most highly regarded early ...

Scios Announces Results From Exploratory Nesiritide Study Providing Important New Renal and Mortality Safety Data with a Neutral Effect on the Primary Endpoint

-- Data from Serial Outpatient Infusion Study in Patients with Chronic Decompensated Heart Failure Presented at the American College of Cardiology 56th Annual Scientific Session -- MOUNTAIN VIEW, Calif. and NEW ORLEANS, March 25, 2007 /PRNewswire/ -- Scios Inc. announced today that an exploratory,...

Results From Trials of DHA in Alzheimer's Disease and Age-Related Cognitive Decline

... DHA for patients with Alzheimer's," Quinn said. In a pre-planned exploratory data analysis, study participants were divided according to whether or not ...amination, another test of mental function. "This is an intriguing exploratory result," said Quinn. "However it must be treated with appropriate caution. ...

First Patient of NOTES Investigational Device Exemption (IDE) Study Successfully Treated With Ethicon Endo-Surgery Devices

...nostic peritoneoscopy with laparoscopic assistance prior to a laparoscopic gastric bypass procedure. The transgastric diagnostic peritoneoscopy is an exploratory surgery of the abdomen with the potential to treat adhesions, biopsy, etc. "Using the Ethicon Endo-Surgery Toolbox, we were able to perform a tho...

SIMPONI(TM) (golimumab) Receives Positive Opinion From CHMP for Once-Monthly Subcutaneous Treatment of Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis

...een more often than in the general population. The potential role of TNF-blocking therapy in the development of malignancies is not known. Based on an exploratory clinical trial in patients with COPD, caution should be exercised when using any TNF-blocking therapy in COPD patients, as well as in patients with an...

ThermoGenesis Announces National Institute of Health Grant

... under this initial contract is completed. "Being awarded this grant is an important milestone for the Company. These funds enable us to conduct exploratory research in animal models to identify the best methods of combining stem cells with biomaterials," noted Mel Engle, Chief Executive Officer of ThermoG...

Results of Two Phase 3 CAPACITY Studies of Pirfenidone in IPF Presented at American Thoracic Society (ATS)

...1, the primary endpoint was not met (p=0.501). An exploratory analysis of pooled primary endpoint data from both...e primary efficacy outcome, InterMune conducted an exploratory analysis that interrogated the time course of the pirfenidone treatment effect. The results of an exploratory repeated measures analysis of ranked change from b...

NovaBay(R) Pharmaceuticals Enters into Agreement to Broaden Intellectual Property Estate and Expand Clinical Opportunities for Its Aganocide(R) Compounds

...e the biological activity of the natural compound while adding pharmaceutically acceptable stability. Professors Gottardi and Nagl have pioneered the exploratory use of NCT compounds in humans in a number of indications that overlap with and even go beyond those for which NovaBay's Aganocide compounds are curre...

Hyperion Therapeutics Announces Results for Phase II Study in Urea Cycle Disorders

... ten adult subjects with UCDs. The primary endpoint was safety; secondary outcome measures included pharmacokinetics (PK), pharmacodynamics (PD), and exploratory efficacy as measured by time-normalized area under the curve (TNAUC) for ammonia. Patients were enrolled on their stable dose of BUPHENYL and 24-hour...

Neurocrine Announces Top-Line Results From 702 Study (Lilac PETAL Study) of Elagolix for Treatment of Endometriosis Pain

... EFFICACY IN VALIDATED ENDPOINTS; MIXED RESULTS IN exploratory ENDPOINTS COMPANY TO HOST CONFERENCE CALL AND...ile limitations were discovered in some of the new exploratory efficacy measures, elagolix again showed strong ef... before utilized in an endometriosis trial. These exploratory endpoints included three daily assessments using a...

Exploratory in Medical Products

SmartPill GI Monitoring System

Description:...a belt or lanyard). The SmartPill Data Receiver records pressure, temperature and pH measurement data, and elapsed and real time. After the outpatient exploratory examination is completed, the patient returns the SmartPill Data Receiver to the Physician who places it in the SmartPill Data Receiver Docking Statio...
Company:SmartPill Corporation

Exploratory in Medical Dictionary

Laparoscopy

...scribes a group of operations performed with the aid of a camera ... Today, exploratory laparoscopy is used after abdominal injury, and in cases of ... From .... Initially, laparoscopy was used for procedures such as tubal ... Today, exploratory laparoscopy is used after abdominal injury, and in cases of ... Provi...

Insulinoma

...rithmic Diagnosis ... Insulinoma is a pancreatic tumor commonly found in ferrets. ... If an insulinoma is diagnosed, you are correct that an exploratory surgery is required. ... INTRODUCTION Low blood glucose concentrations were recognized as a feature of ... Functioning insulinoma -incidenc...

Abdominal exploration

...ow to ... An abdominal exploration , also known as a laparotomy, ... Abdominal exploration . • A • Aug 17 05. Alternative names. Laparotomy; exploratory ... Abdominal exploration is a type of surgery where the abdomen is opened ... Abdominal exploration - Overview, Abdominal explorat...

Exploratory in Biological News

Results from trials of DHA in Alzheimer's disease and age-related cognitive decline

...use of DHA for patients with Alzheimer's," Quinn said. In a pre-planned exploratory data analysis, study participants were divided according to whether or not ...ate examination, another test of mental function. "This is an intriguing exploratory result," said Quinn. "However it must be treated with appropriate caution. ...

Nematode courting caught on camera

...the California Institute of Technology investigated the role of the excitatory neurotransmitter acetylcholine in regulating tail muscles to achieve an exploratory embrace. The video shows an intimate moment between two nematodes of the species Caenorhabditis elegans . As the hermaphrodite does not actively ...

Salt block unexpectedly stretches in Sandia experiments

...it left the surface of the salt. More intense examination showed that surface salt molecules formed a kind of bubble a ductile meniscus with the exploratory tip as it withdrew from penetrating the cube. In this, it resembled the behavior of the surface of water when an object is withdrawn from it. But unli...

Mouse model provides clues to human language development

... neurological functions. The mice carrying the humanized Foxp2 gene showed no physiological abnormalities. However, behavioral tests showed an altered exploratory behavior and reduced movement activity both results point to altered brain functions. Further investigations carried out by the colleagues in Leipzig...

AIBS recognizes diversity in the biological sciences

.... Lee's current research is an examination of individual differences and behavioral syndromes. Her dissertation is titled "Individual differences in exploratory behavior of prairie voles, Microtus ochogaster". Lee is an active member of the Animal Behavior Society (ABS), including ABS's Education and Diversit...

SRI International receives $100,000 Grand Challenges Explorations grant

...y exciting and innovative work," said Dr. Tachi Yamada, president of the Gates Foundation's Global Health Program. "I'm optimistic that some of these exploratory projects will lead to life-saving breakthroughs for people in the world's poorest countries." ...

A genomic CluE for cloud computing

...ven Salzberg, director of the center and Horvitz Professor of computer science, recently received a grant from the National Science Foundation Cluster exploratory Program (CluE) to fund research aimed at discovering how remote cluster computers, computer networks available over the internet, might be used to pro...

Harnessing cloud computing for data-intensive research on oceans, galaxies

...g to teach cloud computing. The projects are funded through NSF's Cluster exploratory program, which will access a cloud datacenter established for educational u... year. Climate modelers are beginning to use computer simulations in more exploratory ways, said Bill Howe, a researcher at the UW's eScience Institute, a newly ...

UGA study reveals ecosystem-level consequences of frog extinctions

...on and was initiated by Catherine Pringle (UGA Odum School of Ecology) and Karen Lips (Southern Illinois University) in 2000 through a Small Grant for exploratory Research (SGER) from the NSF. Connelly and Pringle are monitoring in-stream effects of the population decline on algae, while other team members are s...

SNM releases new fact sheet on breast cancer and molecular imaging

...rly onat its most curable stage; Create a portrait of what cells are doing and how they function over time; Eliminate the need for unnecessary exploratory surgery or multiple surgeries; Provide a painless and cost-effective alternative to more expensiveand less accuratediagnostic tests; Confirm a...

Exploratory in Biological Technology

Charleston Laboratories, Inc. Completes Exploratory Bioequivalence Study of CL-108

CHARLESTON, S.C., May 18 /PRNewswire/ -- Charleston Laboratories, Inc., an emerging specialty pharmaceutical company dedicated to reducing opioid-induced nausea and vomiting (OINV) in opioid pharmaceuticals, announced today they successfully completed the Exploratory Bioequivalence Study on CL-108...

BioMS Medical reports results of exploratory phase II trial of dirucotide in relapsing remitting multiple sclerosis

Toronto Stock Exchange Symbol: MS EDMONTON, Jan. 30 /PRNewswire-FirstCall/ - BioMS Medical Corp. (TSX: MS), a leading developer in the treatment of multiple sclerosis (MS), today announced results from MINDSET-01, an exploratory phase II clinical trial evaluating dirucotide in patients with r...

RVX-208 Exploratory Study Illustrates Early Potential for Alzheimer's Disease

First in class drug illustrates early signal of transport of key amyloid marker from brain TSX Exchange Symbol: RVX CALGARY, Nov. 10 /PRNewswire-FirstCall/ - Resverlogix Corp. ("Resverlogix") (TSX:RVX) announced today that treatment with its lead drug RVX-208, a first in class ApoA-I/Prebet...

InterMune Reports Second Quarter 2009 Financial Results and Business Highlights

...rved with pirfenidone compared to placebo. Adverse events were comparable to previous clinical studies of pirfenidone. New, pre-specified exploratory efficacy data from CAPACITY pertaining to dose-effect relationships, mean change in FVC volume and Six-Minute Walk Test distance that was presented pr...

Nile Therapeutics, Inc. Announces Dosing of First Patient in Phase 2 Study of CD-NP for the Treatment of Acute Heart Failure

...y and tolerability of CD-NP when infused for up to 72 hours in patients with acute heart failure and mild to moderate renal insufficiency. Additional exploratory endpoints will include assessments of CD-NP's ability to relieve symptoms of acute heart failure and its effects on biomarkers of heart failure and re...

Elagolix Successful in Six Month Lilac Petal Study; Safety and Efficacy Confirmed in Patients With Endometriosis

...ly dose, chosen to inform us about the upper limit of dosing, met the pre-defined threshold for bone impact." From an efficacy standpoint, the exploratory daily pain scales for Dysmenorrhea and Non-Menstrual Pelvic Pain demonstrated that women had minimal endometriosis pain symptoms at month six (mean sc...

Nile Therapeutics, Inc. To Raise $3.4 Million in Private Placement

...y and tolerability of CD-NP when infused for up to 72 hours in patients with acute heart failure and mild to moderate renal insufficiency. Additional exploratory endpoints will include assessments of CD-NP's ability to relieve symptoms of acute heart failure and its effects on biomarkers of heart failure and re...

Burnham Institute for Medical Research and Magellan BioScience Group, Inc. Announce Drug Discovery Collaboration

...ers in the United States. The fully-integrated automated system combines robotic screening with high-content image analysis, hit-to-probe chemistry, exploratory pharmacology expertise, and informatics, provides a technology platform that is virtually unprecedented in the not-for-profit research world. &l...

Insmed Announces Results of IPLEX(TM) Phase II Trial in Myotonic Muscular Dystrophy

...aq: INSM ), a biopharmaceutical company, today announced results from its exploratory U.S. Phase II clinical trial evaluating IPLEX(TM) (mecasermin rinfabate) in...U.S. enrolled 69 patients with MMD, for a six-month period. As this was an exploratory trial, a primary endpoint was not pre-defined. The trial explored measures...

OncoGenex Pharmaceuticals Announces OGX-011 Treatment Provides Survival Benefit in Randomized Phase 2 Trial in Advanced Metastatic Prostate Cancer

... Patients treated with OGX-011 had a rate of death 51% lower than patients treated with docetaxel alone (HR=0.49; p=0.012). Additional exploratory analyses found that the lower rate of death was associated with the effect of OGX-011 treatment even when varying amounts of chemother...

Exploratory in Biological Definition

Astrobiology

...ified), making xenobiology a valid field for scientific enquiry. Likewise, computer simulations of basic life processes have made it possible to do exploratory engineering of alternate life forms (like left-handed DNA ) to determine their characteristics. Research primarily involves studying data from te...