Sea skate experiment sheds light on human cell transport
Along with Mark Musch, a longtime University of Chicago collaborator, Goldstein conducted an experiment with the red blood cells of skates to understand how these skinny, graceful fish can swim from salt water to fresh water. For humans, such a drastic environmental change would prompt an equally drastic physiological change: Our cells would take in too much water, diluting blood and other body f...Experiments provide proof of how traveling in groups protects insects
Few events involving animals are more dramatic than when they band together and head out on the march cross-country. Among examples are the many thousands of wildebeests and other hoofed mammals that form herds and migrate across the African plains. and young locusts also sometimes unite with their...Experiments provide proof of how traveling in groups protects insects
Few events involving animals are more dramatic than when they band together and head out on the march cross-country. Among examples are the many thousands of wildebeests and other hoofed mammals that form herds and migrate across the African plains. and young locusts also sometimes unite with their...NIAID Initiates Trial of Experimental Avian Flu Vaccine
Fast-track recruitment has begun for a trial to investigate the safety of a vaccine against H5N1 avian influenza, the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), announced today. Sites in Rochester, NY, Baltimore and Los Angeles will enroll a total of 450 healthy adults. The clinical sites are part of the NIAID-sponsored V...World's largest rainforest drying experiment completes first phase
Scientists with The Woods Hole Research Center are analyzing the surprising results of the first phase of a drydown experiment occurring in the Amazonian rainforest. From January 2000 to July 2004, rainfall was excluded from a one-hectare (2.2 acre) plot in the middle of the Tapajós National Forest, in Brazil. A total of 6 feet of rainfall was diverted with six thousand 2' by 6' clear plas...General Considerations for Successful Transfection Experiments
Keep an eye on your cells; ensure they are in good condition and set a suitable plating protocol for optimal cell density from the beginning to the end of transfection....PCR Grade Deoxynucleotides Additional power to perfect your PCR experiments
Deoxynucleotides are vital components in amplification reactions, and the purityof these reagents significantly influences the results of your experiments. Roche Applied Science developed a new manufacturing and purificationprocess for...Housekeeping Genes: Universal Positive Controls in siRNA Knockdown Experiments
RNA interference is a powerful technique for geneknockdown experiments in academic research and animportant tool for target identification and target validationin therapeutic research. A growing number of different cell lines are us...Choose the Right Transfection Agent for Your RNAi Experiment
The success of any RNA interference experiment depends on the efficient delivery of siRNA or siRNA expression vehicles (plasmids, PCR fragments) into cells. Many researchers use cationic liposomal and polyamine based reagents to deliver these molecules into cultured mammalian c...Designing a Successful qRT-PCR Experiment
A Successful One Step qRT-PCR Experiment Requires Careful Consideration of Several Important Factors: To determine if your gene of interest is represented in an RNA sample, end point PCR followed by gel based staining is suitable. For target q...Experimental treatment for Ebola Virus Shows promising results in mice
Scientists at the Center for Disease Control and Prevention (CDC) in Atlanta, Georgia, have said that an experimental treatment for the deadly Ebola virus has shown promising results in mice. In the study, researchers led by Dr. Manish Gupta took antibodies from the immune systems of mice that had survived infection with the deadly Ebola virus and injected them into other Ebola-free mice...Experimental drug to fight flu
RECENT research has shown that new compounds developed for preventing and treating the flue have shown promise in animal studies, and may require only one dose to be effective.// The compounds, known collectively as multimeric zanamivir, are based on the existing flu drug relenza, or zanamivir, which the U.S. Food and Drug administration approved in 1999 for treating influenza A and B. R...FDA approves Phase 0 trial which tests experimental drugs on humans
Good news for researchers has FDA has approved testing of small quantities of experimental drugs in human beings. Approval of small quantity drug clinical trial will be very helpful for researchers to// understand the path of the drug in the body and its efficacy if the drug is proved effective in small quantities researchers can proceed with a phase I clinical trial. Researchers feel...Experimental vaccine for shingles is effective
Researchers have discovered a newer form of chicken pox vaccine to// effectively control the painful condition called shingles. Shingles (also known as herpes zoster) is the condition that gets symptoms of rashes or blisters on the skin, along with sensations of burning pain, tingling, and numbness on the area. There may be fever with chills, headache or upset stomach. The infection i...Trophos Publishes ALS Article in Journal of Pharmacology and Experimental Therapeutics
Trophos Describes Identification, Characterization and BroadNeuroprotective Properties of TRO19622 in Journal of Pharmacologyand Experimental Therapeutics Neurodegenerative Disease Specialists Publish Details of a NovelDrug Candidate for ALS That Targets Mitochondrial Proteins MARSEILLE, June 19th, 2007 - Trophos SA, a biopharmaceuticalcompany specializing in the discovery an...Alnylam Reports Results of Human Experimental Infection Model with Respiratory Syncytial Virus
CAMBRIDGE, Mass.--(BUSINESS WIRE)--May 7, 2007 - AlnylamPharmaceuticals, Inc. (Nasdaq: ALNY), a leading RNAi therapeuticscompany, presented data from its experimental infection study atthe 2007 Pediatric Academic Societies' (PAS) Annual Meeting beingheld in Toronto. This study represents an important component ofthe company's clinical development program for ALN-RSV01, an RNAitherapeutic fo...