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Exogenous in Medical News

Watson Pharmaceuticals Resumes Shipment of INFeD(R) (Iron Dextran Injection, USP)

...ute phase of infectious kidney disease. Unwarranted therapy with parenteral iron will cause excess storage of iron with the consequent possibility of exogenous hemosiderosis, which is particularly apt to occur in patients with hemoglobinpathies and other refractory anemias. About Watson Pharmaceuticals,...

Stem Cells Buy Freedom From Insulin for Type 1 Diabetics

... holy grail of diabetes research. Some patients have received transplantations of insulin-producing cells from a donor, but none have remained free of exogenous (outside) insulin for longer than five years, said Dr. Spyros Mezitis, an endocrinologist with Lenox Hill Hospital in New York City. This was because ...

Long-term L-carnitine supplementation prevents development of liver cancer

...al protective effects against many mitochondrial toxic agents. It is derived from two sources; endogenous synthesis, in the liver and kidney, and from exogenous dietary sources such as red meat and dairy products. L-carnitine is an essential cofactor for the translocation of long chain fatty acids from the cyt...

Naturally produced estrogen may protect women from Parkinson's disease

...o found that women who were taking hormone therapy did not have a lower risk for Parkinsons. Thus, our data does not support a role for treatment with exogenous hormones, that is, hormones that originate outside the body, to prevent Parkinsons. In fact, hormone therapy can have harmful neurological effe...

Study identifies potential 'safe period' for hormone replacement use

...detrimental for the breast than the use of estrogen alone. But more data from large prospective studies are needed to fully characterize the impact of exogenous hormones on breast cancer incidence by type of hormone preparation and histology of the cancer. To investigate the association in more detail, Amer...

Breast cancer drug shows promise for treating, preventing progestin-dependent tumors

...RIMA-1 also suppressed the emergence of any new progestin-accelerated tumors in the animal model. "Postmenopausal women worldwide are exposed to exogenous progestin in the form of hormone replacement therapy, and clinical studies have associated combined exposure to progestin and estrogen with an increas...
Exogenous in Medical Technology

Pluristem to Present Two Scientific Posters at the International Society for Cellular Therapy

... PluriX(TM) 3D bioreactor that imitates the natural microstructure of bone marrow and does not require supplemental growth factors, cytokines or other exogenous materials. Pluristem believes the resultant expanded cells, termed PLX cells, are multipotent and able to differentiate into a variety of cell types a...

HepaLife Announces Scientific Presentation of PBS-1 Cell Line at International Influenza Meeting

...s, and concerns over existing cell lines, which all require the addition of exogenous agents. The single most important step towards the production of a cell-c...implifying downstream processing. Additionally, PBS-1 cells are free of any exogenous agents, are non-tumorigenic, and are readily adaptable to a variety of cult...

Repros' Androxal Shows Highly Statistically Significant Positive Effects in Men with Secondary Hypogonadism

...as pituitary function is normalized and the subjects benefit from a normal testosterone production and are not subjected to the suppressive effects of exogenous testosterone replacement. Androxal has the potential to change the way in which secondary hypogonadism is treated in the future." Repros anticipates...

Phase III Clinical Trial with 4-Month Long-Acting Formulation of Triptorelin: Ipsen Decides Not to Perform Further Administration

...tary receptor LHRH triggers the release of luteinizing hormone, a key factor for the regulation of reproductive function. Continuous administration of exogenous LHRH or its agonists such as triptorelin leads to a rapid desensitization of its pituitary receptor resulting in a paradoxical effect that translates ...

Pluristem's PLX Cells Demonstrate Potential to Treat Parkinson's Disease

... PluriX(TM) 3D bioreactor that imitates the natural microstructure of bone marrow and does not require supplemental growth factors, cytokines or other exogenous materials. Pluristem believes the resultant expanded cells, termed PLX cells, are multipotent and able to differentiate into a variety of cell types a...

HepaLife's PBS-1 Cells for Influenza Vaccine Production Prove Superior at International Conference

...and MDCK cells, neither CEK cells nor HepaLife's PBS-1 require the need for exogenous proteases, such as Trypsin, therefore eliminating an additional step in man...l lines, and is able to eliminate a cumbersome manufacturing step involving exogenous proteases," explained Mr. Menzler. "Our cell line is able to remain free of...
Exogenous in Medical Products

IGF-II, w/ Extraction IRMA Test

Description:... IGF-II are also dependent on GH secretion. IGF-II levels are low in GH deficiency [7], although IGF-II levels may also decrease in GH excess and with exogenous administration of IGF-I [3]. The combined molar concentrations of IGF-I and IGF-II (i.e. Total serum IGF) is proportional to serum IGFBP-3 and consequ...
Company:Diagnostic Systems Laboratories, Inc.

IGF-II, w/ Extraction ELISA Test

Description:... IGF-II are also dependent on GH secretion. IGF-II levels are low in GH deficiency [7], although IGF-II levels may also decrease in GH excess and with exogenous administration of IGF-I [3]. The combined molar concentrations of IGF-I and IGF-II (i.e. Total serum IGF) is proportional to serum IGFBP-3 and consequ...
Company:Diagnostic Systems Laboratories, Inc.

IGF-II, Non-Extraction IRMA Test

Description:... IGF-II are also dependent on GH secretion. IGF-II levels are low in GH deficiency [7], although IGF-II levels may also decrease in GH excess and with exogenous administration of IGF-I [3]. The combined molar concentrations of IGF-I and IGF-II (i.e. Total serum IGF) is proportional to serum IGFBP-3 and consequ...
Company:Diagnostic Systems Laboratories, Inc.

IGF-II, Non-Extraction ELISA Test

Description:... IGF-II are also dependent on GH secretion. IGF-II levels are low in GH deficiency [7], although IGF-II levels may also decrease in GH excess and with exogenous administration of IGF-I [3]. The combined molar concentrations of IGF-I and IGF-II (i.e. Total serum IGF) is proportional to serum IGFBP-3 and consequ...
Company:Diagnostic Systems Laboratories, Inc.

Calcitonin IRMA Test

Description:... of calcium from bone [1]. This effect is most evident in conditions associated with high levels of bone remodeling (e.g. in Pagets disease) following exogenous administration of calcitonin. Exogenously administered calcitonin has also been shown to reduce pain associated with Pagets disease and malignancy, ap...
Company:Diagnostic Systems Laboratories, Inc.

Calcitonin, Ultra-Sensitive RIA Test

Description:... of calcium from bone [1]. This effect is most evident in conditions associated with high levels of bone remodeling (e.g. in Pagets disease) following exogenous administration of calcitonin. Exogenously administered calcitonin has also been shown to reduce pain associated with Pagets disease and malignancy, ap...
Company:Diagnostic Systems Laboratories, Inc.
Exogenous in Medical Definition

Proteopathy

... protein, or a decrease in its clearance. Advancing age frequently is a risk factor. In some proteopathies, abnormal assembly can be templated on an exogenous protein, typically a misfolded form of the same protein. In this way, the disease state can be induced in a susceptible host by the introduction of di...
Exogenous in Medical Dictionary

Thrombosis

...sis. Venous thrombosis is a common multicausal disease occurring as the result of ... Pregnancy and puerperium still cause thrombosis , as do exogenous hormones in ... Detailed information on thrombosis , including causes, symptoms, diagnosis, and treatment ... Thrombosis occurs when clots ob...

Surfactant

...er selective surfactant administration, reduce mortality and pulmonary ... Abstract and Introduction: A systematic review and meta-analysis of exogenous surfactant administration to assess whether this therapy may be useful in adult ... Surfactant , a short discussion of complex monolayers. ... ...

Precocious puberty

... Precocious puberty is an unusually early onset of puberty , the process of sexual maturation triggered by the brain or exogenous chemicals, which usually begins in late childhood and results in reproductive maturity and completion of growth. Early puberty may be a... Prec...

Porphyria

...ment at Mayo Clinic. ... rare acute intermittent porphyria (AIP) are often ... manifestations of porphyria can be triggered by a variety of exogenous factors ... reported to cause porphyria cutanea tarda. ... ...

Pharmacology

... Pharmacology is the study of drug action. More specifically it is the study of the interactions that occur between a living organism and exogenous chemicals that alter normal biochemical function. If substances have medicinal... In general terms, pharmacology is the science of drug action...

Insulin

...ailable for taking insulin in addition to needles and syringes. ... What alternative devices for taking insulin are available? ... The role of exogenous insulin in treating diabetes mellitus ... Insulin is a hormone produced by the beta cells of the pancreas. ... Type 2 diabetes may be ...
Exogenous in Biological News

DNA repair patterns may predict risk of pancreatic cancer

...th pancreatic cancer and 780 people without cancer. DNA repair is the guardian of the genome. When DNA repair failed to fix the DNA damages caused by exogenous agents such as tobacco carcinogens or endogenous agents such as reactive oxygen species, there is an increased chance of getting cancer. Researc...

Novel technique changes lymph node biopsy, reduces radiation exposure

... Molecules already present in the body (endogenous molecules, as opposed to exogenous ones that are from outside the body), such as melanin, hemoglobin, or lipid.... This allows us to see through the tissue by listening to the sound." exogenous contrast agents, like the gold nanocages developed by Xia's group, can be u...

Novel technique changes lymph node biopsy, reduces radiaiton exposure

... Molecules already present in the body (endogenous molecules, as opposed to exogenous ones that are from outside the body), such as melanin, hemoglobin, or lipid.... This allows us to see through the tissue by listening to the sound." exogenous contrast agents, like the gold nanocages developed by Xia's group, can be u...

New scientific knowledge on juvenile diabetes

...ease in which the immune system attacks the insulin producing pancreatic beta cells. The gradual loss of beta cells results in life-long dependence on exogenous insulin. At the moment, the earliest identifiable process in the pathogenesis of type 1 diabetes has been the development of autoimmunity to pancre...

Ultrasound shown to exert remote control of brain circuits

...trodes, requiring direct contact with nervous tissue or the introduction of exogenous proteins, such as those used for the light-activation of neurons," Tyler ex...uency ultrasound permit deep-brain stimulation procedures without requiring exogenous proteins or surgically implanted medical devices," he adds. Tyler and t...

Scientists from Granada find a potential treatment to prevent diabetes and obesity

...he Baker Heart Research Institute and a member of the Advisory Scientific Committee of Vitagenes, points out that "we obtained surprising results. The exogenous administration of interleukin-6 improved insulin sensitivity and the absorption of glucose, essential for diabetics". In addition, according to Mesa, ...
Exogenous in Biological Technology

Glossary for The BioPharm Guide to Fermentation and Cell Culture

...nisms, often multicellular, whose cells contain nuclei. exogenous Developing from outside, originating externally. exogenous fac tors can be external factors such as food and light that affe...

The Genesis of Gendicine: The Story Behind the First Gene Therapy

...ated endocytosis and begins to over-express the encoded exogenous p53 gene. The overexpressed p53 protein triggers multiple tumor ... minimizing the side effects of Gendicine treatment. expressed exogenous p53 protein can be detected by immunohistochemistry analysis in the int...

The New Affymetrix GeneChip Scanner 3000

... coefficients from Signal values. (Detailed in this Technical Note.) Identify differences in the ability of the scanners to detect and quantify exogenous spiked transcripts in a complex cRNA target background, considering metrics such as Detection call accuracy, Change call accuracy, and Signal Log Rati...

Fine Tuning Your Data Analysis: Tunable Parameters of the Affymetrix Expression Analysis Statistical Algorithms

...alues for individual probe sets can vary. Figure 5 shows Detection p-values for two transcripts expressed in a normal rat heart sample, as well as two exogenous spikes. A given transcripts Detection p-value responds in an individual way to changes in tau, since the p-value calculation is based on how individua...

LIVE/DEAD Viability/Cytotoxicity Assay for Animal Cells Using the SpectraMax Gemini XS Fluorescence Microplate Reader (MaxLine Application Note #43)

...lease. Human Immunology 37: 264-270 (1993). 5. Hausner, J. M. L., Buehrer, B. M., and Bell, R. M. Role of ceramide in mitogenesis induced by exogenous sphingoid bases. J. Biol. Chem. 269: 6803-6809 (1994). 6. Jacobson, M. D., Weil, M. and Raff, M. C. Role of Ced-3/ICE-family proteases in st...

Transient Gene Expression Following Single and Double Exponential Decay Electroporation Pulses

...red... (and) the second low-voltage pulse delivers energy to those cells shocked by the first pulse, therefore favoring entry of exogenous molecules into the cells by means of creating an active electrophoresis field. 1 While the transient formation of pores in the plasma memb...
Exogenous in Biological Products

GenoStat Inducible Expression System from Upstate

Description:... The GenoStat Inducible Expression System provides tightly regulated control of exogenous gene expression in mammalian cells and is capable of repeated on/off expression kinetics. This degree of control is mediated by the highly specific in...
Company:Upstate

PULSin Protein & Antibody Delivery Reagent from Polyplus Transfection

Description:...unctional proteins to the cytoplasm of living cells. Unlike DNA transfection, with PULSin Protein & Antibody Delivery Reagent the amount and timing of exogenous proteins in cells can be controlled, even lethal proteins can now be studied. Real time function blocking and protein localization studies can now be...
Company:Polyplus Transfection

jetSI conc. 10 mM from Polyplus Transfection

Description:... in: Z. Hassani, G.-F. Lemkine, P. Erbacher, G. Alfama, C. Giovannangeli, J.-P. Behr, and B.-A. Demeneix. Lipid-mediated siRNA delivery down regulates exogenous gene expression in the mouse brain at picomolar levels. J. Gene Med., 2005, 7, 198-207....
Company:Polyplus Transfection
Exogenous in Biological Definition

Antigen

...on. We can also classify antigens according to where they come from: exogenous antigens exogenous antigens are antigens that have entered the body, e.g., by inhalation, inge...

Cancer

...to be the result of a long biological process related to the interaction of exogenous exposures with genetic and other endogenous characteristics among susceptib...etrimentally) include certain sexual and reproductive practices, the use of exogenous estrogens, exposure to ionizing radiation and ultraviolet radiation, certai...

Insulin

...s. It also affects other tissues. Insulin is used medically in some forms of diabetes mellitus . Patients with Type 1 diabetes mellitus depend on exogenous insulin (injected subcutaneously) for their survival because of an absolute deficiency of the hormone; patients with Type 2 diabetes mellitus have e...
Exogenous in Biological Dictionary

Transgenic mouse

...e Transgenic Mouse Facility is a core facility that provides ... Transgenic Mouse Facility. 121 BSA ... Transgenic mice provide for the exogenous expression of a protein in some or all ... If no transgenic mice are obtained after 100-egg implantation (this is due to ... ... for the pr...

Transfection

...oration) ... Transfection reagents are highly efficient for plasmid DNA and siRNA ... Transfection is the transient or stable introduction of exogenous molecules and ... Information on FuGene, FuGENE HD, X-tremeGENE siRNA, DOTAP, and DOSPER Transfection Reagents ... DOTAP Liposomal Transfection ...

Testes

... 4.2 Diseases and conditions that affect the testes . 4.3 Effects of exogenous hormones ... Lymphatic drainage of the testes follows the testicular ...m. ... 4.2 Diseases and conditions that affect the testes . 4.3 Effects of exogenous hormones ... Tes┬Ěte n. [So called fr. L. teste , abl. of testis a witn...

Myofibrils

...plinary research from ... the roles played by individual sarcomeric proteins in the assembly of myofibrils . ... Ordered myofibrils containing exogenous human MHC have defined H zones in ... However, it is possible that myofibrils in adult feline myocytes are more ... www.ihop ... become associa...

Exogenous DNA

... exogenous DNA refers to any deoxyribonucleic acid that or...s outside of the organism of concern or study. exogenous (or exogeneous) refers to an action or object c...s, something generated from within the system. exogenous , DNA ,biological ,biology dictionary,biology term...

Cytochromes

...rt. Cytochrome P450 is a very large and diverse superfamily of hemoproteins found in all domains of life. Cytochromes P450 use a plethora of both exogenous and endogenous compounds as substrates in enzymatic reactions. Usually... What is Cytochromes ? Meaning of Cytochromes medical term. What does ...
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