Rigel's R788 Evaluated in Phase 2 Trial in Multiple Cancers
SOUTH SAN FRANCISCO, Calif., June 1 /PRNewswire-FirstCall/ -- Rigel Pharmaceuticals, Inc. (Nasdaq: RIGL ) today announced that its oral Syk inhibitor, R788, is being evaluated in a Phase 2 clinical trial funded, designed and implemented by the National Cancer Institute (NCI), part of the U.S. Na...Weight-Loss Medication Evaluated By Nutrition Expert
A 60 mg low-dose version of the prescription weight-loss medication orlistat (marketed by GlaxoSmithKline as Xenical? 120 mg) was found to be safe, effective and tolerable in overweight individuals,// according to new data presented today at the 2005 Annual Meeting of NAASO, The Obesity Society in ...The Dangers Of Herb-Drugs Evaluated
St. Johns wort is a popular herb taken by many Americans. While some research suggests St. John’s wort interacts with certain drugs and that it can be dangerous,// none of the research has been conclusive. Investigators reviewed 22 research trials that examined drug interactions with St. John’s wor...More Effective Chemotherapy for Breast Cancer Evaluated
Canadian breast cancer researchers have opined on the basis of recent studies that the commonly employed //chemotherapy drugs may not guarantee the prevention of a relapse. AC/T, a widely accepted chemotherapy might be ineffective in preventing a relapse as compared to CEF, which has been pro...The Effectiveness Of NSAIDs Evaluated
Consuming over-the-counter non-steroidal anti-inflammatory pills, will not do much to relieve knee pain associated with osteoarthritis, // say researchers who analyzed the results of 23 studies comparing the drugs to placebos. The study involved nearly 10,900 patients. About 7,800 received NSAI...New Analysis Evaluated Impact of Genetic Variation on Response to Prasugrel
TOKYO and INDIANAPOLIS, Ind., May 5 /PRNewswire-FirstCall/ -- A new substudy from 1,466 patients from the Phase III TRITON-TIMI 38 clinical trial showed that patients who took prasugrel and had a reduced function of the CYP2C19 gene did not have an increased risk of cardiovascular death, heart att...Isis Reports Strong Financial Results and Highlights for Second Quarter of 2009
...ogy," concluded Ms. Parshall. Drug Development Highlights Mipomersen, the most advanced drug in Isis' cardiovascular pipeline, is being evaluated in a broad Phase 3 program in patients who cannot adequately control their cholesterol levels with current therapies and who need new treatment option...Video: FDA Approves INVEGA(R) SUSTENNA(TM) for the Acute and Maintenance Treatment of Schizophrenia
...y improving PANSS scores relative to placebo. The efficacy of INVEGA(R) SUSTENNA(TM) in maintaining symptomatic control in schizophrenia was evaluated in a multicenter, randomized, double-blind, placebo-controlled, parallel-group study (n=410). Time-to-first relapse -- the primary endpoint of the stu...Popular Breast Cancer Drug Used with Certain Antidepressants Puts New Jersey Women at Risk
...ard-looking statement, whether as a result of new information, future events, or otherwise. Forward-looking statements in this press release should be evaluated together with the risks and uncertainties that affect our business, particularly those mentioned in the Risk Factors section of the Company's Annual R...Multi Drug Screen Tests - Rapid Test
Description:...graphy based one step in vitro test. It is designed for qualitative determination of drug substances in human urine specimens. This assay has not been evaluated in the point of care location and is for use by Healthcare Professionals only....Promising new drug being evaluated as possible treatment option for fragile X syndrome
(Chicago) A pilot trial of an oral drug therapy called fenobam has shown promising initial results and could be a potential new treatment option for adult patients with Fragile X syndrome (FXS). Findings of the open label, single-dose study by researchers at Rush University Medical Center and th...Moving to the US increases cancer risk for Hispanics
...es and learn what predisposes different population groups to certain types of cancer, in order to improve health outcomes. Pinheiro and colleagues evaluated the kinds of cancers occurring in each Hispanic population group and compared their risk after moving to the United States. They conducted the study i...Women often opt to surgically remove their breasts, ovaries to reduce cancer risk
...d the increase in risk-reduction surgery among women with breast cancer and evaluated the impact of cancer risk, timing and age. Rate of increase was measure... BRCA2 gene mutations to reduce the risk for breast and ovarian cancer. evaluated by gene type, bilateral risk-reducing salpingo-oophorectomy was more common...National assessment done on potential invasive snail and slug pests in US
...Bulletin is authored by snail/slug biologist Robert H. Cowie of the UH Manoa Center for Conservation Research and Training (CCRT) and his team. They evaluated all known snail and slug pests globally to determine which species would be of greatest concern if introduced nationally, in terms of their potential ...Nanoparticle-delivered 'suicide' genes slowed ovarian tumor growth
...et Sawicki, Ph.D., a professor at the Lankenau Institute for Medical Research. Sawicki and colleagues at the Massachusetts Institute of Technology evaluated the therapeutic efficacy of a cationic biodegradable beta-amino ester polymer as a vector for the nanoparticle delivery of a DNA encoding diphtheria t...Health benefits of physical activity more pronounced in women
...uestionnaire and this was non-scientific, though the particular methodology used has been extremely reliable in other studies. They also note that all evaluated participants were healthy, so these results cannot be generalized to individuals with diabetes or those on cholesterol-lowering medications. ...NeurogesX Reports Second Quarter 2009 Results
...X-5752, novel prodrugs of acetaminophen, have been evaluated in in vivo and in vitro preclinical studies an...ling acetaminophen to a liver protectant, has been evaluated in vitro and in vivo . Equivalent dose levels o...ed in NeurogesX' opioid prodrug platform, has been evaluated in proof of concept in vivo and in vitro precl...GenVec Reports Second Quarter 2009 Financial Results
...ct, TNFerade(TM), is currently in a pivotal clinical study (PACT) in locally advanced pancreatic cancer. TNFerade has also been and is currently being evaluated for its potential use in the treatment of several other cancers, including esophageal cancer, rectal cancer, and head and neck cancer. GenVec also use...ThermoGenesis Provides Update on Fiscal 2009 Results
... positive trends to continue during 2010. Recent addition of the New England Cord Blood Bank as a customer for the AXP. The AXP is also being evaluated at other prospective sites which, if successful, is expected to generate additional revenues. Positive clinical response to the MXP. The Comp...OncoGenex Reports Second Quarter 2009 Financial Results
...wed that OGX-427 was well tolerated as a monotherapy. In addition, OGX-427 demonstrated declines in circulating tumor cells at all doses evaluated as well as evidence of reduction in tumor markers. Reductions in circulating tumor cells and tumor markers both suggest single-agent act...Rabbit Anti-Human PTEN, phospho (Ser385) Antibody, Unconjugated from Upstate
Description:...ng to amino acid region encompassing the human, mouse, and rat phospho-PTEN (Ser385), Accession Number: NM_000314 Quality Assurance: Routinely evaluated by immunoblot. Available Date: 38832...Rabbit Anti-Human IRS1, phospho (Tyr896) Antibody, Unconjugated from Upstate
Description:...ng to amino acid region encompassing the human, mouse, and rat phospho-IRS1 (Tyr896). Accession Number: NM_005544 Quality Assurance: Routinely evaluated by immunoblot. Available Date: 38832...Mouse Anti-Human Clusterin alpha chain Monoclonal Antibody, Unconjugated, Clone 41D from Upstate
Description:...en : Native clusterin purified from human serum Formulation: 0.1M Tris-glycine, pH 7.4, 0.15M NaCl and 0.05% sodium azide Quality Assurance: routinely evaluated on RIPA lysates from HeLa cells or MCF-7 cell lysates. Recognizes clusterin α chain...Anti-MBPK Red, 20X Antibody, Unconjugated from Upstate
Description:...containing MBPK antibody at 20X concentration for use in KinEASE™ 645nm FarRed fluorescence polarization assays. Quality Assurance Routinely evaluated with KinEASE™ 645nm FarRed fluorescence polarization assays. Stability 6 months at -20°C from date of shipment...Rabbit Anti-Human acetyl-Histone H3 (Lys 4) Antibody, Unconjugated from Upstate
Description:...K] corresponds to acetyl lysine 4 of human histone H3 Accession Number: NM_003493 Molecular Weight: Mr ~17kDa Quality Assurance: Routinely evaluated by immunoblot....Rabbit Anti-Human FAK, phospho (Ser843) Antibody, Unconjugated from Upstate
Description:...ing to amino acid region encompassing the human, mouse, and rat phospho-FAK (Ser843) Accession Number: NM_153831 Quality Assurance: Routinely evaluated by immunoblot. Molecular Weight: 125 kDa Available Date: 38903...