evades

Researchers Discover How Cancer Evades the Immune System

A study on various kinds of cancer, conducted by researchers at the University of Southern California, has brought about the discovery of a new method to identify the genetic changes that enable tumours to evade the body's immune system. The findings, demonstrated in human breast and colo...

Herpes Infects Cornea, Evades Immune Cells

Herpes virus has an unusual strategy for infecting cornea cells that may also explain how it evades the immune system, according to a study by researchers// at the University of Illinois at Chicago College of Medicine. The study appears in the Sept. 25 issue of the Journal of Cell Biology. ...

Mass. General-based research center will investigate why immune system fails to control hepatitis C

...epatology in the MGH Gastrointestinal Unit and co-director of the research center. "Improving our understanding of how and why the virus consistently evades immune system control should lead us to better ways of treating hepatitis C and possibly other chronic viral infections." Chung will lead a project t...

TB breakthrough could lead to stronger vaccine

...at prevent the development of stronger immune responses. Investigators at the UT Health Science Center at Houston investigated mechanisms by which BCG evades immune stimulating mechanisms and devised two means to neutralize them. The scientists used genetically-modified organisms and a drug used for organ t...

Study first to show that RNA interference can facilitate vaccine development

...iruses, the exact same strain of RSV can infect the same person repeatedly. Scientists are just now beginning to understand the many ways in which RSV evades the memory immune response, but Tripp's finding reveals that keeping RSV replication and protein expression at a low level prevents the virus from elu...

Study unmasks how ovarian tumors evade immune system

...t tied a specific T cell in the body's defensive immune system to ovarian cancer. "Our study findings lay out for the first time how ovarian cancer evades a critical check-point in the immune response, opening the door to future drug development that can halt, limit, reverse or even bypass the blockage, ...

Future Looks Bright For Non-Invasive Diagnosis Of Skin Cancer; Study Shows Novel Light Device Detects Cancerous Lesions From Normal Tissue

... detect changes brewing beneath the skin before it even raises a red flag.     "Cancers communicate via chemical signaling that evades traditional diagnostics, so we're hopeful that one day this device could listen in to cancer's conversations deep within the skin's surface and alert ...

Drug Re-Sensitizes Breast Tumors to Treatment

..." Isaacs said. "To manage breast cancer long-term, it's apparent that we may need to continually switch drugs to keep up with how a cancer evolves and evades each approach. In a sense, for each step back, we hope to take two steps forward." The study was to be presented Sept. 5 at the 2008 ASCO Breast Ca...

1 step back ... 2 steps forward

...acs concludes. "To manage breast cancer long term, it's apparent that we may need to continually switch drugs to keep up with how a cancer evolves and evades each approach. In a sense, for each step back, we hope to take two steps forward." ...

New Hope Against the Cold Sore Virus

...- until this gene is interrupted somehow," Umbach said. This, then, appears to be the elusive mechanism by which herpes simplex 1 stays dormant and evades drug therapy. The next step, according to Umbach, is to find an agent that blocks LAT RNA, thereby waking up the entire population of virus at once...

evades in Medical Technology

Research Indicates Geron's Human Embryonic Stem Cell-Based Therapeutic for Spinal Cord Injury Evades Direct Attack by the Human Immune System

MENLO PARK, Calif.--(BUSINESS WIRE)--Jun 11, 2007 - Geron Corporation (Nasdaq:GERN) today announced the presentation of research studies indicating that GRNOPC1, the company's human embryonic stem cell (hESC)-based therapeutic for the treatment of spinal cord injury, evades a direct attack by the h...

Researchers Discover Method for Identifying How Cancer Evades the Immune System

PHILADELPHIA, July 3, 2007-- One of the fundamental traits of a tumor – how it avoids the immune system – might become its greatest vulnerability, according to researchers from the University of Southern California. Their findings, demonstrated in human breast and colorectal cancers, ...

New Insight Into the Controls on a Go-To Enzyme

...ze only calpains, rather than mistakenly attach to other similar enzymes in the cell. Furthermore, the researchers discovered how calpastatin evades being chewed up by calpain. Calpastatin's survival enables it to be repeatedly recycled to inhibit calpain, making it an even more effective regulator...

evades in Biological News

Study shows how herpes infects cornea, evades immune cells

Herpes virus has an unusual strategy for infecting cornea cells that may also explain how it evades the immune system, according to a study by researchers at the University of Illinois at Chicago College of Medicine. The study appears in the Sept. 25 issue of the Journal of Cell Biology. Bot...

Alzheimer's, asthma, cancer, malaria and TB focus of new Singapore grants

...wide and kills over 1 million yearly. "A key challenge to successful malaria intervention is our limited understanding of how the malarial parasite evades detection by the spleen our immune system's control centre," said Dr. Preiser. "With this grant, we will use new imaging tools to visualise and meas...

For cancer cells, genetics alone is poor indicator for drug response

...-cell hypothesis. For that, scientists have posited that certain cancers survive standard treatments because a population of tumor-specific stem cells evades chemotherapy or radiation. This paper, however, offers an alternative explanation, namely, that purely through chance, certain cells produce quantitie...

Scientists discover how deadly fungus protects itself

... February 3, 2009 (Bronx, NY) Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered how a deadly microbe evades the human immune system and causes disease. The study, published in the journal Proceedings of the National Academy of Sciences ( PNAS ), may h...

New insight into the controls on a go-to enzyme

...ecognize only calpains, rather than mistakenly attach to other similar enzymes in the cell. Furthermore, the researchers discovered how calpastatin evades being chewed up by calpain. Calpastatin's survival enables it to be repeatedly recycled to inhibit calpain, making it an even more effective regulator...

Deep biosphere research points to new methods for recovering petroleum

...detailed and coherent picture of the global carbon cycle. Yet a complete understanding of how carbon is produced and consumed in the environment still evades researchers because much of what is known is based on processes that act on short time-scales and at Earth's surface. Deep biosphere microbes, lik...

NC State researchers get to root of parasite genome

...deposited in public databases, so other researchers interested in the root-knot nematode - how it develops, establishes a host-parasite interaction or evades host defenses, for example - are now able to use the map of the parasite's genes as a tool to discover more specific information about the parasite. ...

Researchers develop nano-sized 'cargo ships' to target and destroy tumors

...ey.com/journal/121376053/abstract?CRETRY=1&SRETRY=0 "The idea involves encapsulating imaging agents and drugs into a protective 'mother ship' that evades the natural processes that normally would remove these payloads if they were unprotected," said Michael Sailor, a professor of chemistry and biochemis...

Viral recombination another way HIV fools the immune system

...e patient's viral loads stabilized for a while but rose again several months later, when it was found that a second HIV mutation that more effectively evades control by HLA-B27 had developed, possibly in response to a second recombination of viral sequences. "The first Gag recombination event facilitat...

Scripps research scientists reveal key structure from ebola virus

...gether with the viral glycoprotein helps reveal the mechanisms by which the molecules assemble on the viral surface and helps explain how the pathogen evades and exploits the human immune system. The structure also provides a guide for the design of drugs and vaccines to block this protein, potentially prev...

evades in Biological Technology

Cystic Fibrosis - Axentis Pharma Takes Over Patents and Continues Development of Innovative Platform Technology

...ture is marked with ubiquitin. These ubiquitin-marked proteins are degraded by multiple mechanisms prematurely. If this marker is missing, the protein evades destruction and can regulate the concentration of water and salt secretion in the lung despite its minor structural defect. Joerg Zielasek, presiden...

Brown Deer start-up wants to serve up foreign film through broadband box

... only better." Free markets Going one step further, Gupte said movie markets flow more freely when the downloader becomes the vendor and the price evades the impulse to pirate. For instance, software designed at precise points of purchase would make it possible for a client to buy a movie, add subtitles...

New digs for UW AIDS researchers

...rs in the laboratory of David Watkins, professor of pathology and laboratory medicine, announced they'd discovered an important way that the HIV virus evades the body's immune system, the so-called "killer T cells." Now they want to mimic those responses in an AIDS vaccine. The discovery was published in th...