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Eukaryotic in Medical News

J. Craig Venter Institute Awarded $43 Million, Five Year Contract From NIAID to Continue to Develop and Provide Sequencing, Genotyping, and Bioinformatics Expertise and Services in Infectious Diseases

...actor under what was previously referred to as the NIAID Microbial Genome Centers program. During that contract period JCVI sequenced and analyzed 185 eukaryotic and prokaryotic genomes, and more than 3000 viral genomes. JCVI's participation in the NIH Human Microbiome program was also initiated under this con...

E. coli persists against antibiotics through HipA-induced dormancy

...lation occur in bacteria, HipA phosphorylates proteins at their serine or threonine amino acids. This kinase activity is more commonly associated with eukaryotic cells, which make up animals, plants and fungi, and are generally thought to be more complex. "These 'simple bacteria' are so complex. We're findi...

Biologist finds plant polymerases IV and V are really variants of Polymerase II

...nuclear RNA Polymerases IV and V (Pol IV and V), found only in plants, are actually specialized forms of RNA Polymerase II, an essential enzyme of all eukaryotic organisms, including humans. "We've caught evolution in the act," said Craig Pikaard, Ph.D., Washington University professor of biology in A...

Work with fungus uncovering keys to DNA methylation

...ctoral researcher in the Selker lab, document that the enzyme protein phosphatase PP1 is necessary for normal methylation of DNA. In the nucleus of eukaryotic cells, DNA is wrapped around histone proteins to form chromatin, and one histone, H3, turns out to be critical for DNA methylation. "It was long thoug...

Does HBV infection induce acute cellular DNA damage?

... eukaryotic cells employ multiple strategies of checkpoint signaling and DNA repair mechanisms to monitor and repair damaged DNA. There are two branches of the ch...

A potential approach to treatment of hepatitis B virus infection

... eukaryotic cells employ multiple strategies of checkpoint signaling and DNA repair mechanisms to monitor and repair damaged DNA. There are two branches in the ch...
Eukaryotic in Medical Technology

Artelis and Selexis Report Record Antibody Production Levels in CHO Cells of Over 31 Grams Per Liter

...ut the Selexis Genetic Elements(TM): Selexis Genetic Elements (TM) are applied to control the dynamic organization of transgenes in the chromatin of eukaryotic production cells. The Selexis Genetic Elements(TM) enable the creation of loops of open chromatin upon the stable integration of the SGE containing ve...

Senesco's Preclinical Pancreatic Islet Data to be Presented at Upcoming Conferences

...'s Vice President of R&D, Richard Dondero, are both co-authors of the study entitled "In vivo application of siRNA technology reveals a novel role for eukaryotic initiation factor 5A in cytokine-mediated islet dysfunction." Dr. Mirmira will present these results at the Keystone Islet and Beta Cell Symposium w...

Lexicon Pharmaceuticals and Fox Chase Publish Findings on Immune Deficiency

...ertain T cell immune deficiency diseases and some types of lymphoid cancers." Rpl22 is one of several proteins that comprise the large subunit of eukaryotic ribosomes, cellular complexes that are responsible for translating messenger RNA and assembling proteins. Although not-required for translation, Rpl22...
Eukaryotic in Medical Products

hGH ELISA

Description:... of five members of a gene family. The hGH ELISA is used to quantitatively measure the expression of hGH released into the cell culture supernatant of eukaryotic cells transfected with a plasmid containing a reporter gene encoding for hGH. hGH Elisa is standardized, highly sensitive, specific, fast, no leaching...
Company:Roche Diagnostics
Eukaryotic in Medical Dictionary

Yeast

... Yeasts are eukaryotic microorganisms classified in the kingdom Fungi, with about 1,500 species currently described; they dominate fungal diversity in the oceans. Most repro...

Toxins

...verview of the biochemistry and mechanism of action of bacterial toxins from the Center for Disease Control (CDC) ... These toxins , which affect eukaryotic ... Toxins that are insoluble will also dissolve in this water. ... But the stuff about drawing " toxins " out of your body is pure bunk. ... ...

Spores

...extended periods of time in unfavorable conditions. Spores form part of the life cycles of many bacteria, plants, algae, fungi... In contrast to eukaryotic spores , which are produced by many eukaryotes for ... The spore is sometimes surrounded by a thin covering known as the exosporium, ... Simu...

Macrophage

...ting factor, or M-CSF, is a secreted cytokine which influences hemopoietic stem cells to differentiate into macrophages or other related cell types. eukaryotic cells also produce M-CSF in order to... This suggests either that macrophage tropism is defined by structural ... Shioda T, Levy JA, Cheng-Mayer...

Endophthalmitis

...ndophthalmitis may result from various causes such as retained native ... Endophthalmitis ... Severe endophthalmitis . ... Overview: Fungi are eukaryotic organisms that are ubiquitous in nature. ... Endogenous fungal endophthalmitis is frequently an ocular manifestation of a ... Endogenous endo...

Cilia

... A cilium (plural cilia ) is an organelle found in eukaryotic cells. Cilia are tail-like projections extending approximately 5–10 micro...lash") (and not spelt " ... Cilia and and flagella are covered by ... eukaryotic cilia and flagella are specialized organelles found at the periphery ... ...
Eukaryotic in Biological News

JCVI program trains USDA scientists on eukaryotic genome analysis

As part of the ongoing mission to train and educate scientists on the latest tools, methods and advances in genomics, the J. Craig Venter Institute's (JCVI) Eukaryotic Genome Annotation and Analysis Team will travel to Lubbock, TX March 3rd-5th to train 40 United States Agriculture Department (USD...

All eukaryotic kinases share 1 common set of substrates

Kinase mediated phosphorylation is generally recognised as the major regulator of virtually all metabolic activities in eukaryotic cells including proliferation, gene expression, motility, vesicular transport and programmed cell death. Dysregulation of protein phosphorylation plays a major role in ...

Spontaneous assembly

... reproducible for succeeding generations of cells. eukaryotic cells feature distinct subcellular structures, suc...may prove to be widespread in both prokaryotic and eukaryotic cells." Liphardt and his research group are now applying PALM to signaling complexes in eukaryotic membranes to see how widespread is stochastic self...

Cells use import machinery to export their goods as well

...mmon form of cellular export process called constitutive exocytosis, a continual ferrying of goods involved in the regular life and maintenance of all eukaryotic cells. This sort of shipping was assumed to end with the vesicles fusing completely to the membrane and delivering their whole load of proteins and li...

MIT reels in RNA surprise with microbial ocean catch

...e photosynthetic microbe, Prochlorococcus, in the lab created a method for amplifying the RNA extracted from small amounts of seawater by modifying a eukaryotic RNA amplification technique. When Shi began lab studies of the RNA in their samples, she found that much of the novel RNA they expected to be prot...

EMBL scientists develop first fully automated pipeline for multiprotein complex production

...ntly designed to express proteins in the standard system Escherichium coli, the automated pipeline will in future be adapted for complex production in eukaryotic cells. This will allow the study of even larger, more complicated complexes of human origin, including many promising drug targets. The system has alr...
Eukaryotic in Biological Technology

Examples of Electro-Transfected Eukaryotic and Prokaryotic Cells

Mammalian Hamster fibroblast (CHO) Human B Human, B lymphomas: BJAB,P3HR-1, B95-8, UC729-6 Human, B-cell, JY, Epstein-Barr virus transformed Human, C-4I, cervical carcinoma Human epith...

Efficient Cloning and Electro-transformation of Large Eukaryotic DNA Fragments

Contributed by John M. Sedivy, Department of Molecular Biophysics and Biochemistry, Yale University, 333 Cedar Street, New Haven, CT 06510. Introduction Genes of higher eukaryotes can be hundreds of kilobases in size. The need to rapid...

Bacterial RNA Isolation From Infected Eukaryotic Hosts

Remove >90% of mammalian RNA from complex mixtures of host-bacterial samples Simple procedure takes less than 2 hours Works with any bacterial species Seamless integration with MICROB Express ...

Bacterial RNA Isolation From Infected Eukaryotic Hosts

Remove >90% of mammalian RNA from complex mixtures of host-bacterial samples Simple procedure takes less than 2 hours Works with any bacterial species Seamless integration with MICROB Express ...

Eppendorf Multiporator Transfection Protocols for Eukaryotic Cells

Bacteria, gram negative Actinobacillus pleuropnomoniae Actinobacillus pleuropnomoniae eukaryotic cell reproduction that involves mitosis. Both lead to the production of two...

Vacuoles

...lopedia. ... Vacuoles are found in the cells of plants, protists, and some primitive ... Vacuoles are membrane-bound compartments within some eukaryotic cells that serve ... Vacuoles and their contents are considered to be distinct from the cytoplasm, ... Vacuole summary with 7 pages of encycl...

Unicellular

... Of eukaryotic groups, the protists are most commonly unicellular and microscopic. ......lular species, such as baker's yeast (Saccharomyces ... Yeasts are eukaryotic microorganisms classified in the kingdom Fungi, with about 1,500 species...

Tubulin

...1032 β- Tubulin Blocking Peptide ... These straight, hollow cylinders, composed of tubulin proteins, are found throughout the cytoplasm of all eukaryotic cells and perform a number of functions. FUNCTION: Tubulin is the major constituent of microtubules. ... This tubulin does not have a C-termi...

Trans-splicing

... 13 ... In molecular biology, splicing is a modification of an RNA after ... Cis- and trans - splicing of mRNAs mediated by tRNA sequences in eukaryotic cells". Proc. ... leader RNA was tested for trans - splicing function in vivo. by mutating the intron. ... within positions 20 –39 permitted accu...

Transmembrane receptor

...lly activates Alk ... transmembrane - receptor - Ig superfamily ... David Nelson Dec. 14, 2000 Seven transmembrane segment receptors are eukaryotic proteins. ... Searches for seven transmembrane receptors and G- proteins in ... ,biological,biology definition,biology terminology,biology te...

Transient transfection

...s into cells by non-viral methods. The term "transformation" is preferred to describe non-viral DNA transfer in bacteria and non-animal eukaryotic cells; "transduction" is often used to describe virus-mediated DNA... Encyclopedia information on Transient Transfection ... In tran...
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(Date:8/21/2014)... Line: Patients with advanced laryngeal cancer appear to ... surgery than nonsurgical chemoradiation. , Author: Uchechukwu C. ... Medicine at Mount Sinai, New York, and colleagues. ... laryngeal cancer are diagnosed each year and squamous ... these tumors. Prior to 1991, total surgical removal ...
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(Date:8/21/2014)... North Carolina State University have developed a novel and ... has applications for creating new materials as well as ... new technique allows us to model much larger and ... more quickly," says Nan Li, lead author of a ... NC State,s Department of Materials Science and Engineering. "This ...
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