Estrogen

Newly appreciated membrane estrogen receptor important therapeutic target for breast cancer

PROVIDENCE, RI New research at Rhode Island Hospital has uncovered the biological effects of a novel membrane estrogen receptor, a finding that has potential implications for hormonal therapy for breast cancer. The study is published in the July edition of the journal Molecular Endocrinology. T...

New study suggests Rx estrogen delivery through the skin may show safety benefits as opposed to oral delivery

NEW YORK, NY (March 25, 2009) Transdermal delivery of estrogen therapy available by prescription "seems not to alter" the risk of venous thromboembolism (VTE), or blood clotting, in postmenopausal patients when compared to oral delivery, a new study suggests. The study was conducted by researche...

Naturally produced estrogen may protect women from Parkinson's disease

February 25, 2009 (Bronx, NY) Women who have more years of fertility (the time from first menstruation to menopause) have a lower risk of developing Parkinsons disease than women with fewer years, according to a large, new study by researchers at Albert Einstein College of Medicine of Yeshiva Un...

New study finds adverse effects of estrogen replacement therapy are related to the dose

SAN DIEGO, CA Recent clinical trials indicate that estrogen replacement therapy (ERT) may increase the risk of cardiovascular diseases. A new study in mice has examined whether adverse effects of ERT are related to the doses used. The study found that moderate and high doses of ERT increased prob...

New link between estrogen and breast cancer

The female sex hormone estrogen turns on a gene linked to breast cancer, according to new research by Brisbane scientists. The cancer biology team from UQ's Diamantina Institute for Cancer, Immunology and Metabolic Medicine, believe their finding will help explain the link between breast cance...

Previously unseen switch regulates breast cancer response to estrogen

A tiny modification called methylation on estrogen receptors prolongs the life of these growth-driving molecules in breast cancer cells, according to research by scientists at Emory University's Winship Cancer Institute. The results are published in the May 9, 2008 issue of the journal Molecul...

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Estrogen in Medical Technology

Bionovo's Estrogen Receptor Beta Selective Drugs Have Unique Gene Expression and Cell Type Specificity

EMERYVILLE, Calif., July 17 /PRNewswire-FirstCall/ -- Bionovo, Inc. (Nasdaq: BNVI ) announced today that a study of the gene regulation in multiple cell lines by several of their estrogen receptor beta (ERb) candidates will be published in Public Library of Science One. ...

New Study Suggests Rx Estrogen Delivery Through the Skin May Show Safety Benefits as Opposed to Oral Delivery

NEW YORK, March 31 /PRNewswire/ -- Transdermal delivery of estrogen therapy available by prescription "seems not to alter" the risk of venous thromboembolism (VTE), or blood clotting, in postmenopausal patients when compared to oral delivery, a new study suggests. The study was conducted by res...

Bionovo's VG101 Shows Greater Efficacy Than Estrogen in the Treatment of Vaginal Dryness

Results to be Presented at the North American Menopause Society 19th Annual Meeting EMERYVILLE, Calif., Sept. 25 /PRNewswire-FirstCall/ -- Bionovo, Inc. (Nasdaq: BNVI ) will present an abstract in a presentation on their new drug candidate, VG101, for the treatmen...

Bionovo Elucidates Mechanism of Breast Cancer Control by Estrogen Receptor Beta

- Results Presented at Endocrine Society's 90th Annual Meeting - SAN FRANCISCO and EMERYVILLE, Calif., June 16 /PRNewswire-FirstCall/ -- Bionovo, Inc. (Nasdaq: BNVI ) today announced results on the role of estrogen receptor beta in breast cancer growth regulation. The data, which were pre...

Bionovo Discovers New Estrogen Regulatory Elements for Breast Cancer and Osteoporosis Drugs

- Results Presented at Endocrine Society's 90th Annual Meeting - SAN FRANCISCO and EMERYVILLE, Calif., June 16 /PRNewswire-FirstCall/ -- Bionovo Inc. (Nasdaq: BNVI ) today announced results on the role of estrogen regulatory elements important in developing drugs for breast cancer and ost...

New Position Statement from The North American Menopause Society Addresses Use of Local Estrogen for Treatment of Vaginal Atrophy in Postmenopausal Women

CLEVELAND--(BUSINESS WIRE)--May 10, 2007 - An evaluation of the safety and effectiveness of local vaginal estrogen therapy for the treatment of vaginal atrophy, a frequent complaint of postmenopausal women, has just been released by The North American Menopause Society (NAMS). Entitled "The role of...

Estrogen in Medical Products

Estronex 2/16 OH Estrogen Ratio

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

DHEA RIA Test

Description:...roepiandrosterone (DHEA) is produced in the adrenal cortex and, to a lesser extent, the gonads [1,2,3]. DHEA serves as a precursor in testosterone and estrogen synthesis, and has relatively weak androgenic activity, estimated at ~10% that of testosterone [1]. However, in neonates, peripubertal children and in...
Company:Diagnostic Systems Laboratories, Inc.

DHEA EIA Test

Description:...roepiandrosterone (DHEA) is produced in the adrenal cortex and, to a lesser extent, the gonads [1,2,3]. DHEA serves as a precursor in testosterone and estrogen synthesis, and has relatively weak androgenic activity, estimated at ~10% that of testosterone [1]. However, in neonates, peripubertal children and in...
Company:Diagnostic Systems Laboratories, Inc.

DHEA-S-7 RIA Test

Description:...sion of DHEA in adrenal and extradrenal tissues. DHEA is the major C19 steroid secreted by the adrenal cortex, and is a precursor for testosterone and estrogen biosynthesis. DHEA possesses relatively weak androgenic activity, which for unsulfated DHEA has been estimated at ~10% that of testosterone [1]. Howev...
Company:Diagnostic Systems Laboratories, Inc.

DHEA-S-7 EIA Test

Description:...sion of DHEA in adrenal and extradrenal tissues. DHEA is the major C19 steroid secreted by the adrenal cortex, and is a precursor for testosterone and estrogen biosynthesis. DHEA possesses relatively weak androgenic activity, which for unsulfated DHEA has been estimated at ~10% that of testosterone [1]. Howev...
Company:Diagnostic Systems Laboratories, Inc.

DHEA-S-7 (saliva) EIA Test

Description:...sion of DHEA in adrenal and extradrenal tissues. DHEA is the major C19 steroid secreted by the adrenal cortex, and is a precursor for testosterone and estrogen biosynthesis. DHEA possesses relatively weak androgenic activity, which for unsulfated DHEA has been estimated at ~10% that of testosterone [1]. Howev...
Company:Diagnostic Systems Laboratories, Inc.

Estrogen in Medical Definition

Growth attenuation

... Growth attenuation is an elective medical treatment which involves administering estrogen to cause closure of the epiphyses of the bones , resulting in a reduced adult height. Since the 1960s this treatment has been performed primarily ...

Estrogen in Medical Dictionary

Estrogen

Estrogen receptor refers to a group of receptors that are activated by the hormone 17β-estradiol ( estrogen ). Two types of estrogen receptor exist: ER which is a member of the nuclear hormone family of intracellular receptors... Menopause ... The symptoms of menopause are caused by...

Vulvovaginitis

...nital tract" ... Vulvovaginitis , vulvitis, and vaginitis are general terms that refer to the ... Also, vulvovaginitis can be caused by low estrogen levels (called "atrophic ... Free articles and multimedia from The NY Times, including information on symptoms, diagnosis, treatments, tests, and...

Turner syndrome

...for Turner syndrome to occur is, therefore, not associated with the ... Osteoporosis – Women with Turner syndrome who do not get adequate estrogen often ... Diabetes – People with Turner syndrome are at higher risk for Type II diabetes. ... Detailed information on Turner syndrome , in...

Thyroxine

...ockers, Iodide ... Original Article from The New England Journal of Medicine -- Increased Need for Thyroxine in Women with Hypothyroidism during estrogen Therapy Original Article from The New England Journal of Medicine -- Effects of Thyroxine as Compared with Thyroxine plus Triiodothyronine in ...

Soy

...sm. ... A possible relationship between dietary soy and the prevention of hormone ... Soy phytoestrogens are very complex -- they bind to estrogen receptors and ... Mayo Clinic offers award-winning medical and health information and tools for healthy living. ... Soy has been a dietary stap...

Progesterone

...rogesterone achieve their effects ... called the estrogen (or progesterone ) response elements ... Regulation of estrogen and Progesterone ... progesterone natural ...e declines towards the time of delivery, leaving estrogen to increase ... High doses of progesterone ...

Estrogen in Biological News

'New' estrogen receptor found to be key player in tamoxifen resistance

Washington, D.C. Researchers at Georgetown University Medical Center have discovered a novel way in which breast cancer cells become resistant to tamoxifen, the world's largest-selling breast cancer prevention and treatment drug. They say the findings could provide a way to identify tamoxifen us...

Chronic exposure to estrogen impairs some cognitive functions

University of Illinois researchers report this week that chronic exposure to estradiol, the main estrogen in the body, diminishes some cognitive functions. Rats exposed to a steady dose of estradiol were impaired on tasks involving working memory and response inhibition, the researchers found. ...

Improved estrogen reception may sharpen fuzzy memory

GAINESVILLE, Fla. Estrogen treatments may sharpen mental performance in women with certain medical conditions, but University of Florida researchers suggest that recharging a naturally occurring estrogen receptor in the brain may also clear cognitive cobwebs. The discovery suggests that drugs ...

High levels of estrogen associated with breast cancer recurrence

PHILADELPHIA Women whose breast cancer came back after treatment had almost twice as much estrogen in their blood than did women who remained cancer-free despite treatment with anti-estrogen drugs in a majority of the women according to researchers in a study published in the March issue of Canc...

Changing length of days reverses how estrogen affects aggressiveness in mice

New research shows how simply varying the length of daylight to which mice are exposed to can change how aggressively they react to other mice. The study found that in the short days of winter, the class of hormones called estrogens acts to increase aggression in males of a particular type of mo...

New path from estrogen to survival in breast cancer cells described

After years of research, scientists at The University of Texas M. D. Anderson Cancer Center are now able to explain, in exquisite molecular detail, how the estrogen hormone can help keep breast cancer cells alive. In the Sept. 24 issue of the journal, Nature Cell Biology, they assign roles to a ...

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Estrogen in Biological Technology

Bionovo Publishes Discoveries in Predictable Tissue Selectivity for Selective Estrogen Receptor Modulators Platform

EMERYVILLE, Calif., Jan. 2 /PRNewswire-FirstCall/ -- Bionovo, Inc. (Nasdaq: BNVI ) announced today results describing predictable estrogen regulatory elements that can be used to identify estrogenic drugs that are safer. The data, published in Molecular and Cellular Endocrinology, showed tha...

Genomic Health Announces Expansion of Oncotype DX(R) Breast Cancer Test to Include Quantitative Estrogen Receptor (ER) and Progesterone Receptor (PR) Scores

Study Published in the Journal of Clinical Oncology Proves Accurate Measurement of ER and PR Status Using Quantitative Reverse-Transcriptase Polymerase Chain Reaction (RT-PCR) REDWOOD CITY, Calif., June 2 /PRNewswire-FirstCall/ -- Genomic Health, Inc. (Nasdaq: GHDX ) tod...

deCODE Discovers Fourth Major Set of Common Genetic Variants Linked to Risk of Estrogen Receptor-Positive Breast Cancer

Markers will form the basis of a DNA diagnostic test to identify women who may benefit from more intensive screening; latest findings folded into deCODEme(TM) REYKJAVIK, Iceland, April 27 /PRNewswire-FirstCall/ -- Scientists from deCODE genetics (Nasdaq: DCGN ) ...

Analysis of Phenolic Estrogen Mimics in River Water by Negative Ion Electrospray LC/MS/MS

Z. Yang, Varian, Inc. Introduction Bisphenol A (BPA) is a primary raw material used for the production of polyacrylates, epoxy resin, phenolic resin, and polycarbonate plastic. 4-Nonylphenol (4-NP) is a degradation product of alkylphenol ethoxylate detergents used i...

Sanofi-aventis Announces Second Quarter 2009 Results

... product in association with chemotherapy in women with metastatic triple negative breast cancer (mTNBC), i.e. with a tumor that expresses neither the estrogen receptor nor the progesterone receptor and does not over-express the HER2 receptor. Enrolment to the Phase III study, evaluating NV1FGF in crit...

Genomic Health Reports Favorable Commentary on Value of Multigene Assays From the St. Gallen Expert Consensus Meeting on the Primary Treatment of Early Breast Cancer

...in breast cancer treatment planning and selection in Europe. According to the guidelines, the threshold for recommending chemotherapy in treating estrogen receptor (ER) positive, HER2-negative breast cancer is difficult to define. Clinical research in the United States and other countries shows that inf...

Estrogen in Biological Products

ER-beta Fluorescence polarization Assay Kit from Invitrogen

Description:... estrogen Receptor (ER) Competitor Assay Kits Green for estrogen Receptors-alpha and -beta (ER-Alpha and ER-Beta) are ideal for screening novel estrogen receptor binding compounds and endocrine disruptor...
Company:Invitrogen

Rat Anti-Vitamin D Receptor Monoclonal Antibody, Unconjugated, Clone 9A7 from ABR-Affinity BioReagents

Description:...1-710 detects vitamin D receptor (VDR) from human, rat, mouse, hamster, chicken, amphibian, and fish tissues. This antibody does not cross-react with estrogen or glucocorticoid receptors. MA1-710 detects both the occupied and unoccupied forms of the receptor. MA1-710 has been successfully used in Weste...
Company:ABR-Affinity BioReagents

Estrogen in Biological Definition

Anabolism

...r catabolic. Classic anabolic hormones include Growth hormone IGF1 and other insulin-like growth factors Insulin Testosterone estrogen Classic catabolic hormones include Cortisol Glucagon Adrenalin and other catecholamines Cytokines Newer hormones associat...

Cancer

...n E or both experience a reduced incidence of prostate cancer in comparison to men taking placebo pills. Daily use of tamoxifen , a selective estrogen receptor modulator, for up to 5 years, has been demonstrated to reduce the risk of developing breast cancer in high-risk women by about 50%. Cis-re...

Anabolism

...r catabolic. Classic anabolic hormones include Growth hormone IGF1 and other insulin-like growth factors Insulin Testosterone estrogen Classic catabolic hormones include Cortisol Glucagon Adrenalin and other catecholamines Cytokines Newer hormones associat...

Parthenogenesis

...e to their hormonal cycles, which cause some to act as males when levels of estrogen are low, and others to take the role of female when estrogen levels are high. Lizards that act out the courtship ritual have greater f...

Estrogen in Biological Dictionary

Estrogen

From menarche to menopause the primary estrogen is 17β-estradiol. ... In males, estrogen regulates certain functions of the reproductive system ... estrogen is a hormone or chemical messenger produced in both men and women ... Estrogen is probably the most widely known and discusse...

Receptor

...stimulated. alpha and beta receptors ... ... estrogen receptor , accessory proteins, ERE, estrogens, estrogen antagonists, ... Interaction of steroid- receptor... that specifically ... ( receptor ) ... Selective estrogen receptor modulator: Bazedoxifene, ... Inform...

Primary oocyte

...s | Reference ... The primary oocyte produces yolk granules and the follicular cells change from ... is secreted by the primary oocyte . estrogen is secreted by granulosa ... ... oogenesis, only one functional fertilizable cell develops from a primary oocyte . ... to form several layers ...

Polysome

... Polysome preparation and probe labeling were performed as described (3) ... The highest amount of polysome -bound PMR1 was observed prior to estrogen ... Preparation of liver extracts, mRNP and polysome fractions ... ... splicing, translation, polysome , exon junction complex ... mRNA po...

Maternal effect

...rigin of the possible maternal effect in multiple sclerosis is unknown, but ... That there is a maternal effect at all is ... Effect of estrogen on maternal behaviour after hysterectomy + ovariectomy. Summary table: Effect of hormones on maternal behaviour ... To measure the materna...

Hormone

...al mess. For decades, women were told that HRT -- usually a combination of estrogen and ... Explains about hormone therapy, types of therapies, menopausa...al hormone replacement therapy HRT Explains the use of the hormones estrogen and progestin to treat symptoms and side effects of menopause. Hormone...