What is different in reflux esophagitis between African-Americans and non-Hispanic whites?

There is minimal data evaluating the prevalence of GERD complications in any United States general population, other than non-Hispanic whites. Presently, it is thought that such complications occur less frequently in African-Americans than in non-Hispanic whites. A research group in Jacksonville, ...

Is esomeprazole the best choice for reflux esophagitis patients?

In patients with gastroesophageal reflux disease (GERD), esomeprazole, has demonstrated pharmacological and clinical benefits beyond those seen with the other proton pump inhibitors( PPIs ). However it has not hitherto been fully determined whether differences in the onset of antisecreatary activi...

Age, burden, divorce and heavy tea consumption are significant risk factors for erosive esophagitis

Gastroesophageal reflux disease (GERD) is a common disorder with a high incidence rate in adults of 10 - 38%. The diagnosis and treatment of GERD are therefore important because the disease, in addition to the highly disturbing typical symptoms, has a series of known consequences. The presence of ...

Erosive esophagitis healing connected to acid control

Los Angeles – Novel study has shown the direct connection between controlling stomach acid and a remedy for erosive esophagitis that is spurred on by acid reflux disease//. The results of the study and the trial have been presented at the annual Digestive Disease Week. Results from the multi-...

Drug Limits Stomach Trouble in Patients Taking Low-Dose Aspirin

... the famotidine group and in 19 percent of the placebo group. "Famotidine is effective in the prevention of gastric and duodenal ulcers and erosive esophagitis in patients taking low-dose aspirin," concluded Dr. Ali S. Taha, of the University of Glasgow, and colleagues. The findings from the FAMOUS trial w...

AstraZeneca Studies Show Relief of Nighttime Heartburn and Reduction in GERD-Related Sleep Disturbances

... 40 mg and 20 mg daily are indicated for short-term treatment (4 to 8 weeks) in healing and symptomatic resolution of diagnostically confirmed erosive esophagitis (EE). NEXIUM 20 mg is indicated to maintain symptom resolution and healing of EE (controlled studies did not extend beyond 6 months), and for treatmen...

Procter & Gamble Wins Patent Infringement Lawsuit for Osteoporosis Therapy Actonel

...pairment (creatinine clearance < 30 mL/min). Bisphosphonates, including Actonel, may cause upper gastrointestinal disorders such as dysphagia, esophagitis and esophageal or gastric ulcers. Actonel should be taken according to the dosing instructions to minimize the risk of these events. Patients should...

Chronic diarrhea unresponsive to conventional medication: Are you taking lansoprazole?

...iarrhea 4 to 9 times a day. She had interstitial pneumonia at 67 and reflux esophagitis at 70. Lansoprazole 30 mg/day had been prescribed for reflux esophagitis for nearly 6 months. Lansoprazole was withdrawn due to its possible side ef...

Health Alliance Announces First Fracture Protection Program for Actonel(R) (risedronate sodium) Tablets

...irment (creatinine clearance < 30 mL/min). Bisphosphonates, including Actonel, may cause upper gastrointestinal disorders such as dysphagia, esophagitis and esophageal or gastric ulcers. Actonel should be taken according to the dosing instructions to minimize the risk of these events. Patients should...

Alcohol types and socioeconomic status are associated with Barrett's esophagus risk

...ed, studies investigating the association between alcohol intake and reflux esophagitis (RE), Barrett's esophagus (BE) and esophageal adenocarcinoma (EAC) have rep...lcohol consumption in early adulthood may lead to the development of reflux esophagitis (RE), according to a new study in Gastroenterology. However, more recent al...

Esophagitis in Medical Technology

Takeda's Investigational PPI TAK-390MR Demonstrated Higher Healing Rates Compared to Lansoprazole as the Severity of Erosive Esophagitis Grade Increased, a New Integrated Analysis Showed

TAK-390MR Data Presented at the American College of Gastroenterology Annual Meeting ORLANDO, Fla., Oct. 6 /PRNewswire/ -- Combined results from two Phase 3 studies presented at the American College of Gastroenterology Annual Scientific Meeting (ACG) in Orlando, Fla...

Ception Therapeutics Initiates Phase II/III Clinical Trial for Its Lead Product Reslizumab in Eosinophilic Esophagitis (EE) in Children

FDA Also Grants Orphan Drug Status to Reslizumab for Pediatric EE MALVERN, Pa., March 5 /PRNewswire/ -- Ception Therapeutics, Inc. announced today the initiation of a multi-center, Phase II/III clinical trial to evaluate reslizumab, a humanized monoclonal antibody (mAb) against interleukin-...

Meritage Pharma Initiates Phase 2b Clinical Trial of Oral Viscous Budesonide for Pediatric Patients With Eosinophilic Esophagitis

SAN DIEGO, Jan. 22 /PRNewswire/ -- Meritage Pharma, Inc. announced today that it has initiated a dose-ranging Phase 2b clinical trial to evaluate oral viscous budesonide (OVB) for the treatment of children and adolescents with eosinophilic esophagitis (EoE), an allergic inflammatory condition of t...

TAP Pharmaceutical Products Inc. Announces Phase 3 TAK-390MR Data Demonstrating Higher Overall Healing Versus Lansoprazole in Patients with Erosive Esophagitis

-- Additional Data Demonstrated Higher Overall Maintenance of Healed Erosive Esophagitis and Symptom Relief versus Placebo -- SAN DIEGO, May 18 /PRNewswire/ -- TAP Pharmaceutical Products Inc. today reported results from three pivotal Phase 3 studies evaluating investigational new dru...

AstraZeneca Submits NDA for Low Dose Aspirin/Esomeprazole Combination Product

... 40 mg and 20 mg daily are indicated for short-term treatment (4 to 8 weeks) in healing and symptomatic resolution of diagnostically confirmed erosive esophagitis (EE). NEXIUM should be used only for the conditions, dosages, and durations specified in the Prescribing Information. For more information visit...

Cephalon Signs Option Agreement to Acquire Ception Therapeutics

... Trial for the Treatment of Pediatric Eosinophilic esophagitis FRAZER, Pa. and MALVERN, Pa., Jan. 13 /PRN... trial for the treatment of pediatric eosinophilic esophagitis (EE) and in a Phase II clinical trial for the trea...l serve." About Reslizumab and Eosinophilic esophagitis Reslizumab is a humanized monoclonal antibod...

AstraZeneca Submits sNDA for NEXIUM(R) I.V. for Peptic Ulcer Bleed Indication

... treatment (up to 10 days) of GERD adult patients with a history of erosive esophagitis as an alternative to oral therapy in patients when therapy with NEXIUM Dela....V. for Injection as a treatment of GERD patients with a history of erosive esophagitis for more than 10 days have not been demonstrated. For more information vi...

FDA Concludes There is No Increased Risk of Cardiac Events for Patients Treated with omeprazole and NEXIUM(R) (esomeprazole magnesium)

...EC is also indicated for the short-term treatment (4 to 8 weeks) of erosive esophagitis that has been diagnosed by endoscopy. The efficacy of PRILOSEC used for l... these patients has not been established. If there is recurrence of erosive esophagitis or GERD symptoms (e.g., heartburn), additional 4 to 8 weeks courses of omep...

Studies Show Body Mass Index Has No Effect on Resolution and Healing of GERD Symptoms

...ca, LP, Wilmington, DE, USA. (2) Vakil N, Sharma P, Monyak J, Silberg, D: Is Obesity the Cause of Reduced Healing Rates in Advanced Grades of Erosive esophagitis (EE)? The American College of Gastroenterology Annual Scientific Meeting poster. Supported by AstraZeneca, LP, Wilmington, DE, USA. (3) Hampel H, Abr...

New Phase III Data Presented for Once Monthly Dosing Regimen of Risedronate to Treat Postmenopausal Osteoporosis

...for use in patients with severe renal impairment (creatinine clearance Bisphosphonates may cause upper gastrointestinal disorders such as dysphagia, esophagitis and esophageal or gastric ulcer. Patients should pay particular attention to the dosing instructions, as failure to take the drug according to instruc...

Esophagitis in Medical Dictionary

Esophagitis

If caused by GERD, the diseases is also called reflux esophagitis . ... Esophagitis (Candidal) · rupture (Boerhaave syndrome, Mallory-Weiss syndrome) ... Esophagitis is frequently caused by the backflow of acid-containing fluid from ... An autoimmune disorder called eosinophilic e...

Esophagitis in Biological Technology

FDA Approves KAPIDEX(TM) (Dexlansoprazole) delayed release capsules for the Treatment of GERD

...geal Reflux Disease (GERD), the healing of erosive esophagitis (EE) and the maintenance of healed EE. KAPIDEX (30...or lesions can occur, a condition known as erosive esophagitis (EE). About KAPIDEX (dexlansoprazole) de...roved for the healing of all grades of erosive esophagitis (EE) for up to eight weeks, maintaining healing of...

TAP Pharmaceutical Products Inc. Files New Drug Application for TAK-390MR in Patients with Acid-Related Disorders

...nd Drug Administration (FDA) for the use of TAK-390MR in the treatment of acid related diseases and treatment and maintenance of patients with erosive esophagitis and non-erosive reflux disease. TAK-390MR is a proton pump inhibitor that utilizes a novel delivery system. "This compound and its novel delivery sy...