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Erythropoietin in Medical News

National Patient Advocate Foundation (NPAF) Statement Regarding New FDA Label on Erythropoietin Stimulating Agents (ESAs)

WASHINGTON, Nov. 9 /PRNewswire-USNewswire/ -- The non-profit National Patient Advocate Foundation (NPAF), representing the voice of millions of patients assisted nationally in more than a decade through our direct-patient-services affiliate Patient Advocate Foundation (PAF), continues to routi...

3SBio Inc. Announces Unaudited First Quarter 2009 Results

...nt year's presentation basis. First Quarter 2009 Business Highlights: -- EPIAO, the Company's flagship injectable recombinant human erythropoietin ("EPO") products, demonstrated resilient growth despite a challenging environment, with net revenue from EPIAO rising 21.0% over the fir...

Retrospective Analysis Finds Treatment of Cancer Chemotherapy Patients With Epoetin Alfa Associated With Lower Drug Cost Than Darbepoetin Alfa

...penias, associated with neutralizing antibodies to erythropoietin have been reported in patients treated with PROCRI...ssays for binding and neutralizing antibodies. If erythropoietin antibody-mediated anemia is confirmed, PROCRIT sho... Treatment of patients with grossly elevated serum erythropoietin levels (e.g., >200 mUnits/mL) is not recommende...

Anemia Drugs May Raise Death Risk in Cancer Patients

... drugs would still be made available for people for whom transfusion isn't a good option -- but those are very limited circumstances." ESAs include erythropoietin (Epogen, Procrit) and darbepoetin (Aranesp). They work by stimulating the bone marrow to produce new red blood cells, according to the U.S. National I...

The Walter and Eliza Hall Institute Announces the Next Director

...Harvey Lodish. During this time, he worked on trying to understand how the dedicated receptor on the surface of red blood cells recognizes the hormone erythropoietin (also known as EPO), famous for its clinical use in patients with renal failure and infamous for its illicit use by some sports people. Since ret...

Nephros, Inc. Receives the 2009 Frost & Sullivan Medical Device Patient Care Company of the Year Award

...ny inflammation-related parameters, better nutritional indices, reduced beta-2-microglobulin levels, and improved anemia management achieved with less erythropoietin stimulating agents when hemodialysis patients are treated with ultrapure dialysate, in comparison with standard dialysate. Studies have laude...

Monash wins $32m for health and medical research

...Monash University researchers will share in a total of $32M for 62 individual projects, including: $1.8 million for research into the effect of erythropoietin (EPO) on traumatic brain injury; $491,250 to research testicular development and disease; $312,500 to explore novel treatment strategies for c...

Story ideas for health reporters covering the summer Olympic Games

.... Creating reliable tests for these illegal compounds has been difficult. Several recent studies show that testing in humans for both steroids and erythropoietin (EPO), a hormone that induces red blood cell production, is very difficult. In testing for EPO, for example, a study suggests the tests are ineffectiv...

New study examines the validity of epo testing

... BETHESDA, Md. (June 26, 2008)Recombinant human erythropoietin (rHuEpo) is a genetically engineered hormone sometimes misused by high-perf...or. The Study The study is entitled, "Testing for Recombinant Human erythropoietin in Urine: Problems Associated with Current Anti-Doping Testing," and was co...

Anemia Drugs May Speed Tumor Growth in Some Cancer Patients

...her a patient is susceptible to having their tumor progress if treated with erythropoietin and, alternatively, we may be able to predict patients it would be safe to ...revious phase III trial of erythropoietin. Scientists measured levels of erythropoietin receptor (EpoR) messenger RNA (mRNA). High levels of EpoR mRNA in patie...
Erythropoietin in Medical Technology

XTL Biopharmaceuticals Announces the Acquisition of the Use Patent on Recombinant Erythropoietin (rHuEPO) for the Treatment of Multiple Myeloma

REHOVOT, Israel, March 18 /PRNewswire-FirstCall/ -- XTL Biopharmaceuticals Ltd. (Nasdaq: XTLB ; TASE: XTL) announced today that it has entered into an asset purchase agreement with Bio-GAL Ltd, a private company, for the rights to a use patent on Recombinant Erythropoietin ("rHuEPO") for the...

Modigene Announces Successful Completion of Pharmacokinetic & Pharmacodynamic Pre-Clinical Experiments for Proprietary Long-Acting Human Growth Hormone, Long-acting Interferon Beta and Long-acting Erythropoietin

VIENNA, Va., June 20, 2007 /PRNewswire/ -- Modigene Inc., a Nevada corporation today announced the successful completion of pharmacokinetic and pharmacodynamic pre-clinical experiments for long-acting human growth hormone, long-acting interferon beta and long-acting erythropoietin. Modigene's ph...

Final Results of Boceprevir Phase II HCV SPRINT-1 Study Showed Significantly Higher SVR Rates Compared to Standard of Care in Treatment-Naive Genotype 1 Hepatitis C Patients

...the HCV SPRINT-1 study, anemia occurred in approximately half of the patients in the boceprevir arms and over a third of patients in the control arm. erythropoietin (EPO) supplementation was allowed in the study at the discretion of the investigator and was used by 26 percent of patients in the control arm and 39-...

Medgenics' Phase I/II Clinical Trial Now Shows EPODURE Continuous Anemia Treatment Lasting 5 Months in Kidney Disease Patients

... thus effectively treating their anemia without receiving any injections of erythropoietin (EPO) during this period. One of the patients received his last EPO inject...velopment based on this technology: EPODURE - producing erythropoietin (EPO) to treat anemia INFRADURE - producing interferon-alpha (IFN-a...

Medgenics Announces Positive Data From Phase I/II Clinical Trial of EPODURE Treatment of Anemia in Chronic Kidney Disease

...any's ongoing Phase I/II clinical trial, a one-time administration of EPODURE, producing and delivering the low dose of 18-25 IU/kg/day of the protein erythropoietin (EPO), was sufficient to sustain therapeutic elevation of hemoglobin in most patients. The earliest patients to receive treatment have shown sustained...

Observational Study Finds Changes in Medicare Reimbursement for Erythropoiesis-Stimulating Agents Associated With Increased Need for Blood Transfusion

...penias, associated with neutralizing antibodies to erythropoietin have been reported in patients treated with PROCRI...ssays for binding and neutralizing antibodies. If erythropoietin antibody-mediated anemia is confirmed, PROCRIT sho... Treatment of patients with grossly elevated serum erythropoietin levels (e.g., >200 mUnits/mL) is not recommende...

Data From Investigational Use of PROCRIT(R) (Epoetin alfa) Presented at American Society of Nephrology Annual Meeting

...s, associated with neutralizing antibodies to erythropoietin have been reported in patients treated with PROCRI...ssays for binding and neutralizing antibodies. If erythropoietin antibody-mediated anemia is confirmed, PROCRI... Treatment of patients with grossly elevated serum erythropoietin levels (e.g., >200 mUnits/mL) is not recommen...

Soliris(R) Improved Fatigue Independent of Changes in Anemia in Patients with PNH by Controlling Hemolysis

...anges in their anemia. This improvement was larger than the improvement in fatigue reported in a separate study of anemic cancer patients treated with erythropoietin (EPO). Furthermore, in contrast to the improvement in fatigue of anemic cancer patients treated with EPO which occurred only when anemia was also impr...

Observational Studies Assess the Potential Impact of Limiting Erythropoiesis-Stimulating Agent Availability on Frequency of Blood Transfusions

... without other cytopenias, associated with neutralizing antibodies to erythropoietin have been reported in patients with chronic renal failure receiving PRO...27-5624) to perform assays for binding and neutralizing antibodies. If erythropoietin antibody-mediated anemia is confirmed, PROCRIT should be permanently di...

New Data Highlighting Possible Impact of ESA Reimbursement Policies on Patient Care, Nation's Blood Supply, to be Presented at American Society of Clinical Oncology (ASCO) Annual Meeting

... without other cytopenias, associated with neutralizing antibodies to erythropoietin have been reported in patients with chronic renal failure receiving PRO...27-5624) to perform assays for binding and neutralizing antibodies. If erythropoietin antibody-mediated anemia is confirmed, PROCRIT should be permanently di...
Erythropoietin in Medical Products

EPO EIA Human Cytokines 021-SDX021 Erythropoietin Anemia

Description: EPO EIA Human Cytokines 021-SDX021 Erythropoietin Anemia...
Company:ALPCO Diagnostics

Erythropoietin (EPO) ELISA

Description:... is intended for the quantitative determination of erythropoietin (EPO) in human serum. This assay is intended for i...th the advent of the administration of recombinant erythropoietin as a biologic therapy to increase red blood cell mass, an erythropoietin assay may be used also to aid in the prediction an...
Company:MD Biosciences

CGMS System Gold Continuous Glucose Monitoring

Description:... Evaluation of therapeutic changes to medication regimen Evaluation of behavioral modifications affecting glycemic control Patients undergoing erythropoietin therapy because HbA1c may be unreliable. ...
Company:Medtronic MiniMed
Erythropoietin in Medical Dictionary

Erythropoietin

Erythropoietin , or its alternative erythropoetin or EPO, is a glycoprotein hormone that controls erythropoiesis, or red blood cell production. It is a cytokine for erythrocyte precursors in the bone marrow. Also called... Learn about erythropoietin (EPO), and important hormone pro...

Hemoglobin

...low hemoglobin measurement usually means the person has anemia. ... Original Article from The New England Journal of Medicine -- Augmentation by erythropoietin of the Fetal- Hemoglobin Response to Hydroxyurea in Sickle Cell Disease Information about hemoglobin in the free online English dictionary and ...

Blood

...od Funny Cute Baby Kids Playing Fun expressions Mouth Brother Head Cut child ... If one takes a sample of blood , treats it with an agent to ... erythropoietin (EPO), produced by the kidneys, enhances the production of red blood cells (RBCs) ... Get TV Updates. This component requires the FLASH 8 plug-i...
Erythropoietin in Biological News

Brain-nourishing molecule may predict schizophrenia relapse

...DNF levels. Two drugs currently on the market for other medical conditions erythropoietin for anemia and cysteamine for cystinosis can as well. Dr. Pillai hopes his...istered along with any of the above drugs. He adds that both cysteamine and erythropoietin have been well studied for their potential to enhance cognitive function. ...

American Chemical Society's Weekly PressPac -- Aug. 6, 2008

...g drugs, including round-the clock monitoring of urine and blood samples. Many of these tests will focus on identifying human growth hormone (hGH) and erythropoietin (EPO), two products of recombinant DNA technology that athletes have used to boost muscle mass and increase endurance. Although analytical instrum...

Cell Therapy for Cardiovascular Diseases

...cute myocardial infarction will be presented by Dr. Joshua M. Hare MAGIC 5: combined approach using granulocyte colony stimulating factor (G-CSF), erythropoietin mobilization, and intracoronary cell infusion in patients with heart attack, presented in detail here by Dr. Hyo-Soo Kim Data presented by Dr. Han...

A search for protection against chemotherapy cardiotoxicity

...rsity of Grenoble, in France, have discovered that erythropoietin administration prevents acute cardiotoxic effects ...The research article describing this work entitled erythropoietin pretreatment protects against acute chemotherapy t...dioprotective effect afforded by recombinant human erythropoietin (rhEPO) against various stresses, through experime...

Top scientists meet for global conference on stem cell therapy for cardiovascular diseases

...al infarction will be presented by Dr. Joshua M. Hare MAGIC 5: combined approach using granulocyte colony stimulating factor (G-CSF), erythropoietin mobilization, and intracoronary cell infusion in patients with heart attack, presented in detail here by Dr. Hyo-Soo Kim Data present...

Fourth Annual International Conference on Cell Therapy for Cardiovascular Diseases

...cute myocardial infarction will be presented by Dr. Joshua M. Hare MAGIC 5: combined approach using granulocyte colony stimulating factor (G-CSF), erythropoietin mobilization, and intracoronary cell infusion in patients with heart attack, presented in detail here by Dr. Hyo-Soo Kim Bone marrow-derived stem ...

GlycoFi and Dartmouth report full humanization of yeast glycosylation pathway in Science

...yated N-glycans today in the September 8, 2006 issue of the journal Science . To demonstrate the utility of the engineered yeast strains, recombinant erythropoietin (Epo), a protein that stimulates the production of red blood cells, was expressed, purified and its activity demonstrated in vivo. "Re-engineerin...

Mutation in blood stem cells provides clues to cancer development

... mutation in the JAK2 signaling pathway allows the cells to bypass the body's usual mechanism of red blood-cell production, the binding of the hormone erythropoietin (EPO) to its receptor, a process which normally regulates the production of red blood cells. As a result of this intrinsic defect, the bone marrow pr...

Researchers Find Drug May Give Some Cardiac Protection 24 Hours After Heart Attack

...ty in Philadelphia, and his co-workers knew that the drug Darbepoietin alpha would protect the ischemic heart. Darbepoietin is a long-acting cousin of erythropoietin (EPO), which has been shown to offer some protection to the heart from injury from ischemia, or a lack of oxygen. In previous studies, Dr. Koch had gi...
Erythropoietin in Biological Technology

PROLOR Biotech Awarded Two U.S. Patents for Its Longer-Acting Human Growth Hormone and Longer-Acting Erythropoietin

NES-ZIONA, Israel, June 30 /PRNewswire-FirstCall/ -- PROLOR Biotech, Inc. (OTC Bulletin Board: PBTH), formerly Modigene Inc., today announced that the U. S. Patent and Trademark Office (PTO) has issued two new patents for the company's long-acting CTP-enhanced human growth hormone (hGH-CTP) and hu...

Centocor Ortho Biotech Data to be Presented at American Society of Clinical Oncology (ASCO) Annual Meeting

...penias, associated with neutralizing antibodies to erythropoietin have been reported in patients treated with PROCRI...ssays for binding and neutralizing antibodies. If erythropoietin antibody-mediated anemia is confirmed, PROCRIT sho... Treatment of patients with grossly elevated serum erythropoietin levels (e.g., >200 mUnits/mL) is not recommende...

Preclinical Data From Amgen's Oncology Pipeline to be Presented at AACR

...rophages (TAMs) and tumor growth in vivo Lead author: Bonham L. Abstract No. 2077 (Monday, April 20, 2009, 3:40 pm - 3:55 pm) -- erythropoietin Receptor (EpoR) Was Expressed at Low to Undetectable Levels in Tumor Cell Lines: Expression Was Not Regulated by Hypoxia and No Epo-In...

3SBio Inc. Announces Unaudited Fourth Quarter and Fiscal Year 2008 Results

...current year's presentation basis. Fiscal Year 2008 Business Highlights: -- EPIAO, the Company's flagship injectable recombinant human erythropoietin ("EPO") products, continued to outpace EPO market growth in China. Net revenue from EPIAO increased 32.0% year-over-year in the fourth q...

3SBio Inc. Announces Third Quarter 2008 Results

...s: -- Total net revenues increased 21.6% over the third quarter 2007 to RMB68.2 million (US$10.0 million). -- Net revenue from recombinant human erythropoietin ("EPO") products, marketed under the EPIAO brand, increased 17.5% over the third quarter 2007 to RMB42.7 million (US$6.3 million). -- Net rev...

Medgenics Announces Encouraging Preliminary Data For Phase I/II Clinical Trial of EPODURE In Renal Anemia

...treatment of a range of chronic diseases. Medgenics currently has two products in development based on this technology: -- EPODURE -- producing erythropoietin (EPO) to treat anaemia -- INFRADURE -- producing interferon-alpha (IFN-a) to treat hepatitis C The Company has demonstrated proof of principle of t...

3SBio Inc. Announces Second Quarter 2008 Results

...net revenues increased 38.4% over the second quarter 2007 to RMB59.6 million (US$8.7 million). -- Net revenue from our flagship recombinant human erythropoietin ("EPO") products, marketed under our EPIAO brand, increased 23.7% over the second quarter 2007 to RMB37.1 million (US$5.4 million). -- Net re...

Shire Delivers Strong Quarter: Driven by $243m of New Product Sales (+164% YOY Growth). Revenue Guidance Upgrade.

... Changes in the external environment including the launch of several bio-similars at lower prices have proved challenging for DYNEPO, a gene-activated erythropoietin indicated for use in treating anemia associated with kidney disease, making it an uneconomic product for Shire. Product sales will wind down over the ...

3SBio Inc. Announces First Quarter 2008 Results

...ncreased 56.8% over the first quarter 2007 to RMB55.5 million (US$7.9 million). -- Net revenue from our flagship injectable recombinant human erythropoietin ("EPO") products, marketed under our EPIAO brand, increased 41.2% over the first quarter 2007 to RMB35.5 million (US$5.1 million). -- Net rev...

Ortho Biotech Modifies Prescribing Information for PROCRIT(R) (Epoetin alfa)

... without other cytopenias, associated with neutralizing antibodies to erythropoietin have been reported in patients with chronic renal failure receiving PRO...27-5624) to perform assays for binding and neutralizing antibodies. If erythropoietin antibody-mediated anemia is confirmed, PROCRIT should be permanently di...
Erythropoietin in Biological Products

Human Erythropoietin, Unconjugated from R&D Systems

Description:... Recombinant Human erythropoietin (Tissue Culture Grade)...
Company:R&D Systems
Erythropoietin in Biological Definition

Hormone

...sin, AVP) atrial-natriuretic peptide (ANP, also atriopeptin) calcitonin cholecystokinin (CCK) corticotropin-releasing hormone (CRH) erythropoietin ( EPO ) follicle stimulating hormone (FSH) gastrin glucagon gonadotropin-releasing hormone (GnRH) growth hormone-releasing hormone...

Kidney

...talsis . Renal functions Renal functions include the excretion of waste material from the bloodstream, secretion of hormones - particularly erythropoietin and renin and maintaining serum electrolyte, acid-base levels and osmolality. For more info see Renal physiology . Diseases and disorders ...
Erythropoietin in Biological Dictionary

Glycoprotein

...col. ... Information about glycoprotein in the free online English ... erythropoietin - a glycoprotein secreted by the kidneys that stimulates the ... Onlin...ry), ...descendants requires particular kinds of CSFs; for example, the CSF erythropoietin is ... Cancer is a leading cause of death worldwide with WHO global esti...
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