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Erythematosus in Medical News

Anxiety and depression lower quality of life in majority of systemic lupus erythematosus patients

Copenhagen, Denmark, Friday 12 June 2009: 92.8% of patients with systemic lupus erythematosus (SLE) suffer anxiety and depression which significantly affects both their physical and emotional quality of life (QoL), according to the results of a new study presented today at EULAR 2009, the Annual C...

Novel DNA vaccine leads to kidney damage prevention in systemic lupus erythematosus models

Copenhagen, Denmark, Thursday 11 June 2009: DNA vaccination using lupus autoantigens and interleukin-10 (IL-10, a cytokine that plays an important role in regulating the immune system) has potential as a novel therapy to induce antigen specific tolerance and may help to prevent kidney damage in pa...

Uptake of Branded Agents Will Drive the Systemic Lupus Erythematosus Drug Market to Quadruple to $1.4 Billion in 2016

Entry of Novel Therapies Including Rituxan/MabThera and Increased Uptake of CellCept Will Provide Effective Treatment Options, According to a New Report from Decision Resources WALTHAM, Mass., Feb. 25 /PRNewswire/ -- Decision Resources, one of the world's leading research ...

Reminder - Human Genome Sciences to Host Conference Call to Discuss Top-Line Phase 3 Results for BENLYSTA(TM) (Formerly LymphoStat-B(R)) in Systemic Lupus Erythematosus

ROCKVILLE, Maryland July 20 /PRNewswire-FirstCall/ -- Human Genome Sciences, Inc. (Nasdaq: HGSI ) will host a conference call today at 8:15 AM Eastern to discuss the results from BLISS-52, the first of two pivotal Phase 3 clinical trials of BENLYSTA(TM) (belimumab, formerly Ly...

Ovarian function and fertility preserved in women with severe systemic lupus erythematosus

Paris, France, Thursday 12 June 2008: Ovarian function can be preserved and disease activity controlled in women with severe systemic lupus erythematosus (SLE) when treated with a 6-month course of cyclophosphamide (CYC), a chemotherapy drug, followed by the immunosuppressant mycophenolate mofeti...

Oral contraceptives safe for women with Lupus erythematosus

Lupus erythematosus (lupus) is a disease in which the body's immune system mistakenly attacks and damages healthy tissues of the skin, joints and internal organs.// A study has found that women who suffer from this disease can take oral contraceptives safely without any complications like increased...
Erythematosus in Medical Technology

Human Genome Sciences and GlaxoSmithKline Announce Positive Phase 3 Study Results for BENLYSTA(TM) in Systemic Lupus Erythematosus

ROCKVILLE, Maryland and LONDON, July 20 /PRNewswire-FirstCall/ -- Human Genome Sciences, Inc. (Nasdaq: HGSI ) and GlaxoSmithKline PLC (GSK) today announced that BENLYSTA(TM) (belimumab, formerly LymphoStat-B(R)) met the primary endpoint in BLISS-52, the first of two pivotal P...

Human Genome Sciences Reports Positive Long-Term Data for LymphoStat-B in Patients With Active Systemic Lupus Erythematosus

- Phase 2 data demonstrate sustained improvement in disease activity through three years of LymphoStat-B (belimumab) therapy - - No increase in adverse events, malignancies, infections or laboratory abnormalities over time - ROCKVILLE, Md., June 12 /PRNewswire-F...

Tolerx Achieves Milestone with Completion of Phase Ib Clinical Study of TRX1 in Cutaneous Lupus Erythematosus

CAMBRIDGE, Mass., Jan. 15 /PRNewswire/ -- Tolerx, Inc., a biopharmaceutical company engaged in the discovery and development of novel therapies for the treatment of immune-mediated diseases, announced today the successful completion of a Phase Ib clinical study of TRX1, a novel humanized anti-...

Human Genome Sciences Reports Positive Data from Long-Term Treatment with LymphoStat-B(R) in Patients with Active Systemic Lupus Erythematosus

- Sustained improvement in disease activity observed through 2.5 years of LymphoStat-B therapy in a Phase 2 continuation trial - - No observed increase in rates of adverse events, serious adverse events, malignancies and infections over 2.5 years of LymphoStat-B treatment - ROCKVILL...

Coley Pharmaceutical Group Diversifies Pipeline with First-in-Class TLR Antagonist for the Treatment of Systemic Lupus Erythematosus

-- CPG 52364, Coley's First Orally-Available, Small Molecule Drug Candidate, Enters Phase I Clinical Development -- WELLESLEY, Mass., Oct. 29 /PRNewswire-FirstCall/ -- Coley Pharmaceutical Group, Inc. (Nasdaq: COLY ), today announced that it has dosed its first subject in a Phase...

Human Genome Sciences Reports That a Phase 2 Study of LymphoStat-B Showed Significant Reductions in Disease Activity in Patients with Active Systemic Lupus Erythematosus

-LymphoStat-B(R) significantly reduced signs and symptoms of SLE disease at 52 Weeks and demonstrated durable clinical and biological activity at 76 weeks- ROCKVILLE, Md., June 14, 2007 /PRNewswire-FirstCall/ -- Human Genome Sciences, Inc. today announced the presentation of Phase 2 trial data dem...
Erythematosus in Medical Products

Systemic Lupus Erythematosus (SLE) Latex Test

Description: Latex agglutination slide test for the qualitative and semi-qualitative detection of antinuclear antibodies to aid in the diagnosis of systemic lupus erthyematosus....
Company:Inverness Medical Innovations

ImmunoDOT™ DNA/ENA Autoimmunity Screening Panel

Description:...oantibodies against various specific nuclear antigens (ANA, DNA, SS-A/SS-B, RNP/Sm) in serum, and is used as an aid in the diagnosis of systemic lupus erythematosus (SLE), mixed connective tissue disease (MCTD), and Sjgren's syndrome....
Company:GenBio

ImmunoDOT Autoimmunity Screening Panel 6

Description:...gainst various specific nuclear antigens (SS-A, SS-B, RNP/Sm, Sm, Jo-1, and Scl-70) in serum, and is used as an aid in the diagnosis of systemic lupus erythematosus (SLE), mixed connective tissue disease (MCTD), Sjgren's syndrome and other rheumatoid diseases....
Company:GenBio

ImmunoDOT Autoimmunity Screening Panel 4

Description:... against various specific extractable nuclear antigens (SS-A, SS-B, RNP/Sm, and Sm) in serum, and is used as an aid in the diagnosis of systemic lupus erythematosus (SLE), mixed connective tissue disease (MCTD), and Sjgren's syndrome....
Company:GenBio

ImmunoWELL Cardiolipin Antibody (IgM) Test

Description:... detection of antibodies to cardiolipin antigen in serum and is used as an aid for assessing the risk of thrombosis in individuals with systemic lupus erythematosus (SLE) and lupus-like disorders....
Company:GenBio

ImmunoWELL Cardiolipin Antibody (IgG) Test

Description:... detection of antibodies to cardiolipin antigen in serum and is used as an aid for assessing the risk of thrombosis in individuals with systemic lupus erythematosus (SLE) and lupus-like disorders....
Company:GenBio
Erythematosus in Medical Dictionary

Systemic lupus erythematosus

Systemic lupus erythematosus is a chronic autoimmune connective tissue disease that can affect any part of the body. As occurs in other autoimmune diseases, the immune system attacks the body’s cells and tissue, resulting in... Get information on lupus (SLE) disease treatment, s...

Lupus erythematosus

Systemic lupus erythematosus is a chronic autoimmune connective tissue disease that can affect any part of the body. As occurs in other autoimmune diseases, the immune system attacks the body’s cells and tissue, resulting in... Lupus erythematosus is a connective tissue disease. ...

Discoid lupus erythematosus

Discoid lupus erythematosus can be divided into localized, generalized and childhood discoid lupus erythematosus . Discoid lupus erythematosus information including symptoms, diagnosis, misdiagnosis, treatment, causes, patient stories, videos, forums, prevention, and prognosis. ...

Turner syndrome

... Genetic Features of Turner Syndrome (National Institute of Child ... Article: 46,X,del(X)(q13) Turner's syndrome women with systemic lupus erythematosus in a... In Turner syndrome , cells are missing all or part of an X chromosome. ... Growth hormone may help a child with Turner syndrome g...

Systemic sclerosis

...F. Haustein, MD. Dermatology Online ... Systemic sclerosis (SSc) is a clinically heterogeneous generalized disorder ... ... systemic lupus erythematosus and scleroderma (also known as systemic sclerosis ) ... Because systemic sclerosis patients do not always tolerate conventional ... The S...

Systemic

...temic risk. about 85 more... Systemic Lupus erythematosus (SLE) Authored by: Becky Lundgren, DVM. Systemic lupus erythematosus (SLE) is a fairly rare chronic and potentially ... Systemic lupus erythematosus (SLE) is a chronic, often life-long, ... Systemic...
Erythematosus in Biological News

Genes linked with lupus are revealed, giving hope for new treatments

...re Genetics. In an international genetic study of more than 3,000 women, researchers found evidence of an association between Lupus (systemic lupus erythematosus or SLE) and mutations in several different genes. The findings, by scientists from Imperial College London and institutions in the USA and Sweden...

DNA variations signal lupus risk

...lished in the journal Nature Genetics . The study, the largest of its kind to date, is the work of the International Consortium for Systemic Lupus erythematosus (SLEGEN), of which UAB is a member. SLE is the medical term for systemic lupus erythematosus, a common form of the disease. Looking at the genomes ...

Steps toward Stopping Autoimmune Disease

...ndmark genetic study has identified multiple genes linked to systemic lupus erythematosus (SLE), or lupus, a debilitating autoimmune disease that affects an estimate... Lupus Research (ALR) formed and supported the International Systemic Lupus erythematosus Genetics (SLEGEN) Consortium, charging scientists with searching for genet...

UT Southwestern secures $5 million NIH grant for lupus research

... grant from the National Institutes of Health to fund the Center of Research Translation, which will investigate the autoimmune disease systemic lupus erythematosus (SLE). There are a limited number of these centers around the country, so this is a major accomplishment for UT Southwestern, said Dr. David Karp, ...

Lupus gene finding prompts call for more DNA samples

...as called for more patients to volunteer DNA samples to enable them to further study the underlying causes of the disease. Lupus or Systemic Lupus erythematosus (SLE) is an autoimmune disease which frequently causes skin rash, joint pains and malaise, but can also lead to inflammation of the kidneys and other...

HGS announces positive Phase 2 LymphoStat-B at ACR meeting

...se flares over time, and was well tolerated through 2.5 years on treatment in combination with standard of care in patients with active systemic lupus erythematosus (SLE). The results will be the subject of an oral presentation today in Boston at the Annual Scientific Meeting of the American College of Rheumatolo...
Erythematosus in Biological Technology

Trubion Pharmaceuticals, Inc. Announces Initiation of Phase 1 Study of SBI-087 for the Treatment of Systemic Lupus Erythematosus (SLE)

SEATTLE, March 25 /PRNewswire-FirstCall/ -- Trubion Pharmaceuticals, Inc. (Nasdaq: TRBN ) announced today that its collaboration partner Wyeth Pharmaceuticals, a division of Wyeth (NYSE: WYE ), has initiated a Phase 1 clinical trial of SBI-087, Trubion's next generation CD20 drug candidate, fo...

Human Genome Sciences to Host July 20 Conference Call to Discuss Top-Line Phase 3 Results for Benlysta(TM) (Formerly Lymphostat-B(R)) in Systemic Lupus Erythematosus

ROCKVILLE, Maryland, July 1 /PRNewswire-USNewswire/ -- Human Genome Sciences, Inc. (Nasdaq: HGSI ) today announced that it expects to have top-line results available on Monday, July 20, from BLISS-52, the first of two pivotal Phase 3 clinical trials of BENLYSTA(TM) (belimumab, formerly LymphoSta...

Human Genome Sciences Reports Positive Long-Term Data for BENLYSTA(TM) (Formerly LymphoStat-B(R)) in Patients With Active Systemic Lupus Erythematosus

- Phase 2 continuation data demonstrated sustained improvement in disease activity and patient response rate through four years of BENLYSTA therapy - - Frequency of disease flares as measured by the SELENA SLEDAI flare index and by BILAG A or B organ domain scores decreased over four years o...

Trubion Pharmaceuticals Inc. Announces Work-Force Reductions and Restructuring

... Phase 1 rheumatoid arthritis trial data by end of Q4 2009 (currently enrolling; conducted by Wyeth) -- Initiate SBI-087 Phase 1 systemic lupus erythematosus trial by end of Q1 2009 (conducted by Wyeth) "Concentrating our resources on our clinical stage product candidates, as well as our preclinica...

Cephalon's New Product Launches Pace Record 2008 Sales

...seases. Recently we announced a number of deals including the worldwide license for the drug candidate LUPUZORTM, for the treatment of systemic lupus erythematosus and the option to acquire Ception Therapeutics including its drug candidate reslizumab for eosinophilic esophagitis. Our ability to move quickly when...

Corgenix Receives Two Additional Patents on AtherOx(R) Technology

... be a more physiologic and accurate way of assessing the risk of progressive atherosclerotic cardiovascular disease in individuals with systemic lupus erythematosus and lupus-like disorders. Corgenix licensed this technology in 2002, and is developing additional products utilizing this unique platform. In additi...
Erythematosus in Biological Definition

Apoptosis

...l factor in the pathogenesis of numerous diseases including cancer, neuro-degenerative and ischemic diseases, AIDS and autoimmunity. In systemic lupus erythematosus (SLE) the antigen responsible for most anti-DNA antibodies, exclusively generated in this disease, are derived from nucleosomes. As nucleosomes are ma...

Immune system

... On the other end of the scale, an overactive immune system figures in a number of other disorders, particularly autoimmune disorders such as lupus erythematosus , type I diabetes (sometimes called "juvenile onset diabetes"), multiple sclerosis , psoriasis , and rheumatoid arthritis . In these the immune s...

Immunology

...es include chronic granulomatous disease ), and autoimmunity , in which the immune system attacks its own antigens (examples include systemic lupus erythematosus , rheumatoid arthritis , Hashimoto's disease and myasthenia gravis ). Other immune system disorders include different hypersensitivities , in whi...
Erythematosus in Biological Dictionary

Serosa

...y adventitia a layer ... The serosa reduces friction as the digestive system organs work and slide across ... Clinical overview of Systemic Lupus erythematosus (SLE), a chronic, ... the joints, skin, kidney, brain, lung, heart, serosa and gastrointestinal tract. ... ... the internal reproductive organs o...

Pericardium

...icles on Diseases of the pericardium ... Ongoing Trials on Diseases of the pericardium at Clinical Trials.gov ... pericardium . systemic lupus erythematosus ... Chest x-rays may detect calcium deposits in the pericardium . ... Normally, the pericardium is less than 1/8 inch ... Chest x-rays may detec...
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