Gene Therapy Eradicates Pancreatic Cancer in Mice
Researchers at the University of Texas M. D. Anderson Cancer Center have found in pre-clinical trials that a molecularly engineered therapy selectively embeds a gene in pancreatic cancer that shrinks or eradicates tumours, inhibits metastasis, and prolongs survival virtually without toxicity. ...Combining targeted therapy drugs may treat previously resistant tumors
...als, and in this paper we show that, while either agent alone has a minor effect on K-Ras-driven tumors in mice, combining inhibitors of both pathways eradicates these tumors with minimal toxicity." Kwok-Kin Wong, MD, PhD, of DFCI, also a co-corresponding author, adds, "The results of our study are truly re...JCI online early table of contents: April 8, 2008
...f the vaccination is combined with treatment with a neu-specific antibody, the efficient antitumor response enables mice to remain tumor-free and even eradicates transplanted neu-expressing tumors. In this study, the combination therapy was shown to markedly improve the CD8+ T cell antitumor immune response by ...New strategies work to put cancer on the firing line
...ransportation. The vector obviously good at getting in and surviving in the body will ideally help generate a potent, memorable immune response that eradicates cancer or an infection in the first place then leaves an immune army waiting should it return. Vaccination is by far the most effective approach fo...Surgeons Remove Gallbladder Through Vagina
...ate the potential for natural orifice transluminal endoscopic surgery in improving patient care," the researchers wrote. "A surgical intervention that eradicates the need for any incision, avoiding bodily trauma, is attractive to patients and also has an aura that surgeons find hard to resist." But Ren thin...Helicobacter pylori Antibiotic Treatment of Peptic Ulcer May not Prevent Gastric lymphomas
...so a causative agent of gastric lymphoma, specifically gastric B cell lymphoma of mucosa-associated lymphoid tissue (MALT). While antibiotic treatment eradicates the bacteria and promotes tumor regression, the effects of re-infection on disease are more severe. Dr. Mueller's group used a mouse model of Hel...MIT Holding, Georgia Southern University, and MEVLABS successfully test the PROVECTOR
...sing illness in hundreds of thousands of people. Dengue cases have also been reported on the border of the United States. The PROVECTOR geographically eradicates the problem while preventing negative impact within the ecosystem. William C. Parker, Chief Executive Officer of MIT Holding, Inc., said, This is ...Protein found that slows hepatitis C growth in liver cells
... Hepatitis C chronically infects approximately 170 million people worldwide. The most effective treatment for the virus, interferon-based therapy, eradicates the virus less than 50 percent of the time and causes debilitating side effects. Those for whom that treatment fails are at high risk for fatal cirrho...A Jekyll and Hyde of cytokines: IL-25 both promotes and limits inflammatory diseases
... fight infection. In mice that lack the ability to produce IL-25, researchers saw a dramatic reduction in the ability to mount a type 2 response that eradicates the parasites. Furthermore, in the absence of IL-25, mice developed a destructive inflammatory response similar to that observed in models of inflamm...Dangerous tricksters: Some bacterie use immune cells to reproduce
...estigate which bacterial features are important for preventing the merger of phagosomes and lysosomes, and how the immune system normally successfully eradicates an infection despite all the tricks the bacteria use. Rhodococci, incidentally, can also cause diseases resembling TB in AIDS patients which may be...Medical Breakthrough ... Doctor Discovers 'Penetrating Carrier' That Eradicates Fungus
Innovative Custom Products, Inc., has obtained exclusive distribution rights to a 'first of its kind' product line, CureCeuticals, invented by Dr. Marc Selner, a nationally renowned Sports Podiatrist; Cure Toenail Fungus and Cure Athlete's Foot. MILWAUKEE, Nov. 7 /PRNe...