Epilepsy

Catastrophic Epilepsy Caused by Defect in One Gene

Mouse study led to discovery of mutation and could advance treatments WEDNESDAY, July 8 (HealthDay News) -- A mutation in a single gene causes catastrophic epilepsy, U.S. scientists say. And that finding, they say, could lead to treatments or a cure for the disorder. People with cat...

Findings in Epilepsy Gene in Animals May Guide Treatment Directions for Infants

PHILADELPHIA, June 1 /PRNewswire-USNewswire/ -- Researchers studying a difficult-to-treat form of childhood epilepsy called infantile spasms have developed a line of mice that experiences seizures with features closely resembling those occurring in patients with infantile seizures. These genetical...

Findings in epilepsy gene in animals may guide treatment directions for infants

Researchers studying a difficult-to-treat form of childhood epilepsy called infantile spasms have developed a line of mice that experiences seizures with features closely resembling those occurring in patients with infantile seizures. These genetically engineered mice provide a new opportunity for...

'Singing brains' offers epilepsy and schizophrenia clues

Studying the way a person's brain 'sings' could improve our understanding of conditions such as epilepsy and schizophrenia and help develop better treatments, scientists at Cardiff University have discovered. Research by a team working in Cardiff University's Brain Research Imaging Centre (CUB...

The Epilepsy Foundation Commends Rock Star Prince for Talking About It

WASHINGTON, April 28 /PRNewswire-USNewswire/ -- The Epilepsy Foundation applauds legendary rock star Prince for sharing his childhood experiences with epilepsy. Prince revealed he had epilepsy during PBS's Tavis Smiley show . The award-winning musician said, "I used to have seizures when ...

Pregnant Women With Epilepsy Should Avoid Valproate

New guidelines stress that, with good planning, most moms-to-be will do fine,,,, MONDAY, April 27 (HealthDay News) -- Despite recent concerns about fetal malformations linked to the anti-seizure medication valproate, most women with epilepsy can expect to have a relatively uneventful ...

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Epilepsy in Medical Technology

Video: UCB Launches Vimpat(R) in the U.S. for Add-On Treatment of Epilepsy in Adults

- New antiepileptic drug with novel mechanism of action helps address critical unmet medical need for many people living with uncontrolled epilepsy - Vimpat(R) offers hope to people with epilepsy who still have uncontrolled partial onset seizures with current treatment ATLANTA, May 26 ...

VIDEO from Medialink and the Epilepsy Foundation: New Study Suggests Different Versions of the Same Epilepsy Medication Can Be Harmful

WASHINGTON, May 12 /PRNewswire/ -- The Epilepsy Foundation recently announced findings that show people with epilepsy, whose seizures have been controlled with a consistent drug therapy, have a greater chance of increased seizures, greater side effects or sudden death when their medications are sw...

Retigabine Significantly Reduces the Number of Seizures in Adults With Inadequately Controlled Partial-Onset Epilepsy

SEATTLE, Dec. 6 /PRNewswire-FirstCall/ -- Results from RESTORE 2, a placebo-controlled, Phase III study demonstrated that the investigational compound retigabine significantly reduced the number of seizures in adult patients with refractory partial-onset epilepsy when a 600 mg or 900 mg dose was a...

New Data Show Efficacy of Zebinix(TM) in the Treatment of Epilepsy

PORTO, Portugal, September 24 /PRNewswire/ -- - Novel Treatment Also Demonstrated Significant Improvement in Quality of Life and Reduction in Depressive Symptoms Positive data from three phase III studies presented today at the 8th European Congress of Epileptology, Berlin, Germany, demons...

Data Presented at AAN Support Potential for Adjunctive use of Intravenous Lacosamide as Short-Term Replacement for Oral Treatment in Partial Epilepsy

SMYRNA, Ga., April 18 /PRNewswire/ -- Data presented today at a platform session of the 60th Annual Meeting of the American Academy of Neurology (AAN) in Chicago support the potential for adjunctive use of intravenous lacosamide 200-600 mg/day using infusion durations as fast as 10 minutes for...

New Data Published in Neurology Show Once-Daily Lamictal XR Significantly Reduced Partial Seizures in Patients with Epilepsy

Investigational Extended-Release Formulation Reduced Seizures in Patients Who Were Inadequately Controlled RESEARCH TRIANGLE PARK, N.C., Oct. 15 /PRNewswire-FirstCall/ -- New recently published data show that Lamictal(R)XR(TM) (lamotrigine) Extended- Release Tablets significa...

Epilepsy in Medical Products

Integra Epilepsy Sphenoidal Electrodes

Description: Sphenoidal electrodes provide a less invasive method of recording brain activity in the epilepsy patient. Like all Integra Epilepsy electrodes, sphenoidal electrodes are fabricated from implant-grade stainless steel or platinum materials...
Company:Integra LifeSciences Corporation

Integra Epilepsy Foramen Ovale Electrodes and Accessories

Description: Foramen ovale electrodes typically are guided through the foramen ovale and are positioned on the medial surface of the temporal lobe. The ultra-thin 1.0 mm diameter electrodes are flexible yet firm enough to allow guidance to the desired target point....
Company:Integra LifeSciences Corporation

Integra Epilepsy Specialty Electrodes

Description: Dual-sided, Interhemispheric Grid Electrode with 16 Contact Leads; Cortical Grid Electrode with 16 Contact Leads; Pediatric Grid Electrode with Flex Connector, 0.5 cm spacing...
Company:Integra LifeSciences Corporation

Integra Epilepsy Epidural Peg Electrodes and Accessories

Description: Peg electrodes typically are positioned in a burr hole to enable epidural recording of brain activity. They have platinum contacts and are furnished in several lengths to accommodate various skull thicknesses. A 4.6 mm twist drill is suitable for installation of peg electrodes in the patient....
Company:Integra LifeSciences Corporation

Integra Epilepsy Depth Electrodes

Description: These are superior quality electrodes, fabricated from a single length of polyurethane tubing for strength and uniform smoothness. They are furnished with a specially-designed rigid stylet to facilitate stereotactic placement in the patient....
Company:Integra LifeSciences Corporation

Integra Epilepsy Strip Electrodes

Description: Integra Epilepsy cortical strip electrodes are extra thin and flexible to facilitate intracranial placement through a burr hole. The narrow cylindrical connector design simplifies tunneling and enables quick and secure attachment to the patented connection system. Like all Integra Epilepsy electrod...
Company:Integra LifeSciences Corporation

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Epilepsy in Medical Definition

Breath-holding spells

...t after 5 years of age. They are unusual before 6 months of age. A positive family history can be elicited in 25% of cases. It is often confused with epilepsy . There are two types of breath holding spells. Cyanotic breath-holding spells are usually precipitated by anger or frustration although they may ...

Epilepsy in Medical Dictionary

Epilepsy

Epilepsy is a common chronic neurological disorder characterized by recurrent unprovoked seizures. These seizures are transient signs and/or symptoms of abnormal, excessive or synchronous neuronal activity in the brain. About... Epilepsy and seizure disorders information page compiled...

Toxocariasis

..... Toxocariasis is a zoonotic (animal to human) infection caused ... Toxocariasis is one of the most commonly reported zoonotic helminth ... epilepsy and seizure diagnosis, treatment, and information for Professionals ... Toxocariasis is caused by nematodes of the genus Toxocara. ... Causal ...

Titer

...easures the presence and amount of ... Depending on the strength of the titer , this could mean that your immune system ... Learn about canine epilepsy and medications used to contol seizures in dogs. ... Taking blood for an annual titer test, to check a dog's level of immune defenses, ... ...

Temporal

...ited by time: a temporal dimension; temporal and spatial boundaries ... world; worldly: the temporal possessions of the ... temporal -lobe epilepsy ( ′temprəl ¦lōb ′epə′lepsē ) ( medicine ) Recurrent seizures originating in lesions of the temporal lobe of the The term Temporal Logic h...

Temporal lobe seizure

...occur as a single ... Diagnosis of temporal lobe seizure is suspected primarily on the basis of the ... The seizures of temporal lobe epilepsy (TLE) can start at almost any age. ... Some people with temporal lobe seizures are candidates for surgery. ... Temporal lobe seizure ...

Stimulants

...s are substances that induce a number of characteristic symptoms. ... effects of the more common stimulants are discussed in other articles ... epilepsy and seizure diagnosis, treatment, and information for Professionals ... Stimulants ... Currently available stimulants and the dose ranges approv...

Epilepsy in Biological News

Drops in blood oxygen levels may be key to sudden death in some epilepsy patients

(SACRAMENTO, Calif.) A new study by researchers at UC Davis Medical Center suggests that the sudden unexplained deaths of some epilepsy patients may be a result of their brains not telling their bodies to breathe during seizures. "Significant drops in blood oxygen levels are more common than w...

Brain study may lead to improved epilepsy treatments

Using a rodent model of epilepsy, researchers found one of the bodys own neurotransmitters released during seizures, glutamate, turns on a signaling pathway in the brain that increases production of a protein that could reduce medication entry into the brain. Researchers say this may explain why a...

Early treatment stops epilepsy in its tracks

New Haven, Conn.Yale School of Medicine researchers have shown for the first time that it is possible to suppress the development of epilepsy in genetically predisposed animalswhich could open the door to treating epilepsy as a preventable disease. According to the study published this month i...

Rutgers research tackles childhood epilepsy

NEW BRUNSWICK, N.J. Rutgers researchers have discovered a potential new way to treat childhood epilepsy using a widely available therapeutic drug. Rutgers neuroscientist Gabriella D'Arcangelo and her colleagues have published their research findings in the journal Disease Models and Mechanism...

Drug prevents seizure progression in model of epilepsy

PITTSBURGHCarnegie Mellon University researchers have identified a new anticonvulsant compound that has the potential to stop the development of epilepsy. The findings are published in the March issue of the journal Epilepsia . The research discovery builds on previous work identifying a sp...

Researchers discover that gene switches on during development of epilepsy

WINSTON-SALEM, N.C. A discovery made by researchers at Wake Forest University School of Medicine while studying mice may help explain how some people without a genetic predisposition to epilepsy can develop the disorder. In a study published this month in the Journal of Neuroscience , senior ...

Epilepsy in Biological Technology

Victhom announces the filing of a patent application to address sudden unexplained death in epilepsy (SUDEP)

QUEBEC, Feb. 11 /PRNewswire-FirstCall/ - Victhom Human Bionics Inc., "Victhom" (TSX: VHB), announced today the filing of a patent application for the detection and treatment of a physiological disorder that most likely leads to sudden unexplainable death in epileptic patients during seizure. Vic...

Multiple Vimpat(R) (lacosamide) Studies Presented at American Epilepsy Society Annual Meeting

ATLANTA, Dec. 8 /PRNewswire/ -- UCB today announced new findings from analyses of pooled Vimpat(R) (lacosamide) clinical trial data, demonstrating that the new antiepileptic drug (AED) starts working during the first week of treatment and across doses in a challenging patient population, when admi...

Beyond Seizure Control in the Treatment of Epilepsy With New Anti-Epileptic Drug, Zebinix(TM)

PORTO, Portugal, December 8 /PRNewswire/ -- - Data Highlight The Efficacy, Safety and Significant Improvement in Quality of Life and Depressive Symptoms With Zebinix(TM) (Eslicarbazepine Acetate) Positive data from three phase III studies presented today at the American Epilepsy So...

Synosia Announces Encouraging Results of Proof-of-Concept Clinical Trial for Epilepsy Drug rufinamide as a Treatment for Mood Disorders

Speed in Reaching First Clinical Milestone Validates Approach SAN FRANCISCO, January 22 /PRNewswire/ -- Synosia Therapeutics today announced the successful completion of its first clinical trial, a proof-of-concept study that evaluated new therapeutic options for SYN-111 (rufinamide), a s...

UCB Announces New Data Showing Investigational Drug Lacosamide Significantly Reduced Seizures in Refractory Epilepsy Patients

ATLANTA, Dec. 3 /PRNewswire/ -- UCB today announced new data demonstrating that the investigational drug lacosamide, with the proposed brand name Vimpat(TM), administered as oral, adjunctive therapy, significantly reduced the frequency of seizures and was generally well-tolerated in patients w...

Biovista Inc. Announces Positive Efficacy Results in a Pre-Clinical Trial of its BVA-601 Repositioned Drug for Epilepsy

CHARLOTTESVILLE, Virginia, June 23 /PRNewswire/ -- Biovista Inc. today announced that BVA-601, its small-molecule drug targeting epilepsy, has shown positive results in the Kainic acid murine model of temporal lobe epilepsy. BVA-601, an existing drug that Biovista repositioned in epilepsy, exh...

Epilepsy in Biological Definition

Neural tube

...aly , encephalocele , and spina bifida . The incidence of neural tube defects is 2.6 in 1,000 worldwide. Pregnant women taking medication for epilepsy have a higher chance of having a child with a neural tube defect. Research has shown that women with folic acid deficiences also have a higher cha...

Epilepsy in Biological Dictionary

Mispairing

...1976; 264(5584):369-70 (ISSN: 0028-0836) ... The point mutation in the tRNA(Lys) gene of mitochondrial DNA (mtDNA) from patients with myoclonic epilepsy and ragged red fibers (MERRF) was quantitatively analyzed ... In the present work, mispairing frequency of fU with G and cellular repair ... Mis...

Consanguinity

... videos, listen to free streaming mp3s, & read Consanguinity's blog. that there is significantly higher rate of consanguinity of parents of epilepsy patients. ... and consanguinity in the department of Neurology, G.B Pant ... ...