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India Approves Baraclude? (entecavir) For Treatment Of Chronic HEPATITIS B

Bristol-Myers Squibb has announced the launch of BARACLUDE? (entecavir) for the treatment of chronic hepatitis B virus infection //following its approval by the Drug Controller General of India. BARACLUDE (entecavir) is indicated for the treatment of chronic hepatitis B virus infection in adults with evidence of active viral replication and either evidence of persistent elevations in...

Challenges in Entecavir Drug Treatment

According to a new report in the New England Journal of Medicine,treating hepatitis B patients with the drug entecavir can cause those who are also infected with HIV to become resistant to two of the most important drugs in the anti-HIV arsenal. the researchers reported that a patient infected with both hepatitis B and HIV who was treated with entecavir developed a mutant strain of H...
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Baraclude (Entecavir) Treatment Demonstrated Greater Viral Load Reduction Compared to Adefovir at 48 Weeks in Study of Antiviral-Naive Chronic Hepatitis B E-Antigen Positive Patients

WASHINGTON, May 21, 2007/PRNewswire-FirstCall/ -- Bristol-MyersSquibb Company (NYSE: BMY) today announced new data from studyETV-079, which showed that treatment with Baraclude (entecavir)demonstrated greater viral load reduction than adefovir at 48 weeks-- a result that was also seen at weeks 12 (primary endpoint) and24. These data from an open-label, randomized viral kinetics studyof 6...

Baraclude (entecavir) Therapy Resulted in Undetectable Levels of Hepatitis B Virus in Cohort of Patients Who Re-Started Treatment

93 Percent of Nucleoside-Naive Chronic Hepatitis B e-Antigen(HBeAg)-Negative Patients Achieved Undetectable Viral Load by Week48 of Re-Treatment PRINCETON, N.J., April 13, 2007 /PRNewswire-FirstCall/ --Bristol-Myers Squibb Company today announced data from a cohort ofnucleoside-naive HBeAg-negative chronic hepatitis B patients(ETV-027/901, n=99). These data showed that patients whoexperi...
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