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Encoded in Medical News

Scientists Decode HIV Genome

...s that cause influenza, hepatitis C and polio, HIV carries its genetic information as single-stranded RNA rather than double-stranded DNA. Information encoded in RNA is more complex. The HIV RNA genome is huge, composed of two strands of almost 10,000 nucleotides each. Previously, scientists had managed t...

Health Story Project Offers Perspective on "Meaningful Use" Definition

...onal document services turn clinical dictation directly into structured and encoded clinical documents which makes it easy to share information across provider...d narrative in one document." This use of structured narrative and encoded data supports the Committee's observations regarding meaningful use: -&nbs...

Study in Nature: MicroRNAs hold promise for treating diseases in blood vessels

...rentiation and growth. Gene expression is the process where information encoded in genes is converted into proteins, the workhorse molecules that make up the body's structures and carry its signals. While genes are encoded in chains of deoxyribonucleic acids (DNA), they are copied into chains of m...

Roux-en-Y weight loss surgery raises kidney stone risk

...ts who had similar characteristicsincluding age, gender, and body mass indices that indicate obesitybut not the surgery. Using medical information encoded in the database for both patient populations, the researchers looked to see which patients were either diagnosed with kidney stones or had treatment f...

Dad's Genes May Play Greater Role Than Thought

...packaging in sperm," he said. "This firmly shows that information that's there can be information that is passed across generations and that is not encoded in DNA," Kelly said. More information The Yale Fertility Center has more on the causes and treatment of infertility . ...

Expression of infrared fluorescence engineered in mammals

...several reasons. "First, all fluorescent proteins derived from corals, jellyfish, and now bacteria are powerful in basic research because they are encoded by a gene," said Tsien. "Introducing such genes into people would pose big scientific and ethical problems." He explained that, secondly, humans a...
Encoded in Medical Technology

Researchers Create First Targeted Knockout Rats Using Zinc Finger Nuclease Technology

...t gene for rat antibody production. Inactivation of rat IgM expression is the first step in generating rats that exclusively express human antibodies encoded by transgenic human immunoglobulin genes. "Creating a knockout rat was the biggest challenge OMT faced," said Dr. Roland Buelow, CEO of OMT and a sen...

Fruitfly Model of a Neuropathic Disease Demonstrates Novel Role for Proteins in the Family of aTyr Pharma's Product Class

...w mutations in the tRNA synthetase gene disrupt the neurological system of a complex organism, this study showed that there are neurological functions encoded in this gene." According to Jeff Watkins, CEO of aTyr Pharma, "In the past few years, Professor Schimmel has discovered a whole new area of biolo...

MultiCell Technologies Signs Liver Stem Cell R&D Agreement To Develop Products for the Study of Liver Cancer

...f life science research reagent tool kits which can be used to isolate liver stem cells, and help to elucidate liver stem cell gene function and their encoded proteins. MultiCell plans to further leverage this research effort involving liver stem cells to identify therapeutic targets, and diagnostic a...

International Team Locates Key Player in Muscle Regeneration

...n and is necessary for the genetic reprogramming required to complete the muscle tissue regeneration process. "By administering cdk9-55 or a protein encoded by a cdk9-55 gene directly to the muscle or on a resorbable material applied to injured or diseased muscle tissue or to an area missing muscle tissue,...

Vical Advances RapidResponse(TM) DNA Vaccine Platform Under $6 Million Grant from NIH

...ery that administering polynucleotides such as DNA or RNA to tissues, without the use of viral delivery vehicles, may cause expression of the proteins encoded by the polynucleotides. Vical's patent coverage includes delivery of linear DNA as well as plasmid DNA. Currently plasmid DNA vaccines, which are un...

Genetic Immunity to Present at 2008 BIO International Convention

...of concept with the DermaVir Patch, which includes HIV-specific plasmid DNA encoded antigens. About Genetic Immunity(R) Genetic Immunity is a US/Hungarian ...ented nanoformulation technology that includes disease-specific plasmid DNA encoded antigens. DermaPrep is the topical administration device that delivers Nano...
Encoded in Medical Products

Leptin IRMA Test

Description:... Leptin is a proteohormone with a molecular weight of 16 kDa. Leptin is a protein encoded by the ob gene and produced by adipocytes [1,2]. Leptin is thought to play a key role in the regulation of body weight [1-3]. In the human, leptin l...
Company:Diagnostic Systems Laboratories, Inc.

Leptin Soluble Receptor ELISA Test

Description:... Leptin is a 16kDa peptide encoded by the ob gene and is produced exclusively by adipocytes. It is believed to play a key role in the regulation of body weight by influencing energy int...
Company:Diagnostic Systems Laboratories, Inc.

Leptin ELISA Test

Description:... Leptin is a proteohormone with a molecular weight of 16 kDa. Leptin is a protein encoded by the ob gene and produced by adipocytes [1,2]. Leptin is thought to play a key role in the regulation of body weight [1-3]. In the human, leptin l...
Company:Diagnostic Systems Laboratories, Inc.

Eclipse TE2000E2

Description:...nger, fluorescence shutter, nosepiece, condenser, DIC Analyzer, and filter wheels. Boasting a new Remote Satellite Fine Focus and Nano-Position Linear encoded z-axis drive system, the TE2000E2 provides greater precision, improves fine focus, and allows the user to easily bring the microscope back to the same...
Company:Nikon

Eclipse TE2000E

Description:...tics, and extendible infinity design make it the perfect imaging workstation. In addition, its super-nanoprecision z-axis motorized focus with linerar encoded feedback control is perfect for precise imaging in 3D. It's the first inverted microscope to take full advantage of and utilize the infinity space....
Company:Nikon

Biomedical Systems' Cardiology Services

Description:...s' centers receive and process Holter, cardiac event, blood pressure monitoring, ECG, and pacemaker data. We provide accurate, timely reports that are encoded and transmitted to our clients' offices quickly and efficiently. Single reports can be faxed anywhere in the world and verbal reports can be given ins...
Company:BioMedical Systems
Encoded in Medical Dictionary

Von Hippel-Lindau

...ippel Lindau (VHL) disease was first described at the beginning of the 20th ... The Von Hippel - Lindau tumor suppressor protein is encoded by the VHL gene and ... The von Hippel - Lindau Tumor Suppressor Gene and Kidney Cancer" ... Article describes von Hippel - Lindau disea...

Tryptophan

... Tryptophan is one of the 20 standard amino acids, as well as an essential amino acid in the human diet. It is encoded in the standard genetic code as the codon UGG. Only the L-stereoisomer of tryptophan is used in structural... Physician reviewed L-tryptophan ...

Protein

... protein is a biological polymer comprising numerous amino acids linked ... The sequence of amino acids in a protein is defined by a gene and encoded in the ... Information Staff, Agricultural Research Service, USDA. Communicating news and information about ... Moreover, the soy- protein -substi...

Haptoglobin

... Haptoglobin is a protein that in humans is encoded by the HP gene. In blood plasma, haptoglobin binds free hemoglobin (Hb) released from erythrocytes with high affinity and thereby inhibits its o...

Factor XII

...so known as factor XII . It is the zymogen form of factor XIIa, an enzyme (EC 3.4.21.38) of the serine protease class. In humans, factor XII is encoded by the F12 gene. factor XII ( ′faktər ′twelv ) ( biochemistry ) A blood clotting factor effective experimentally only in vitro; deficient ...

Disk

... A hard disk drive is a non-volatile storage device that stores digitally encoded data on rapidly rotating platters with magnetic surfaces. Strictly speaking, "drive" refers to a device distinct from its medium, such as a ...
Encoded in Biological News

Rodent social behavior encoded in junk DNA

A discovery that may someday help to explain human social behavior and disorders such as autism has been made in a species of pudgy rodents by researchers funded, in part, by the National Institutes of Health's (NIH) National Institute of Mental Health (NIMH) and National Center for Research Resour...

DNA computation gets logical at the Weizmann Institute of Science

...s of DNA representing the rules, facts and queries were assembled by a robotic system and searched for a fit in a hierarchical process. The answer was encoded in a flash of green light: Some of the strands had a biological version of a flashlight signal they were equipped with a naturally glowing fluorescen...

Fox Chase researchers uncover one force behind the MYC oncogene in many cancers

...t a limb, for example. In adults, such genes are almost entirely inactive. After their previous studies demonstrated that expression of the protein encoded by the DLX5 gene correlated with that of the MYC gene, Testa and Jinfei Xu, PhD, a research associate in the laboratory, used a luciferase assay deve...

Baylor researchers unravel mystery of DNA conformation

...leagues tackled. Their results also addresses a question posed by another Nobel laureate, the late Dr. Linus Pauling, who asked how the information encoded by the bases could be read if it is sequestered inside the DNA molecular with phosphate molecules on the outside. It's easy to explain when the cel...

Gene evolution process discovered

...ng how specific traits develop in offspring. The study shows that REST controls the process by which proteins are made, following the instructions encoded in genes. It also reveals that while REST regulates a core set of genes in all vertebrates, it has also evolved to work with a greater number of gene...

Protein linked to mental retardation controls synapse maturation, plasticity, CSHL team finds

...xcitatory synapses. They have also made important progress in elucidating the pathophysiology of mutations in the OPHN1 gene. The protein normally encoded by the OPHN1 gene belongs to what scientists call the Rho subfamily of GTP-binding proteins. "Members of this family are known to be key regulators o...
Encoded in Biological Technology

Preparative SDS-PAGE Electrophoresis of a Recombinant Epstein-Barr Virus Encoded Protein and Its Application in Serodiagnostic Test Systems, Rev C

Udo Reischl and Christian Gerdes, Institute of Medical Microbiology and Hygiene, University of Regensburg, 93053 Regensburg, Germany Abstract Serodiagnosis of Epstein-Barr virus (EBV) infection is currently based on the detection of ...

Polycystic Kidney Disease Assay at Cornell University Uses Transgenomic's Surveyor Nuclease & WAVE Technology

...wide, about 10 million. It is the most commonly inherited kidney disease. In 85% of ADPKD cases, the disease is caused by altered polycystin proteins, encoded by the PKD1 and PKD2 genes. As diagnosis in young people can be ambiguous, genetic analysis gives a strong indication of disease prognosis. Curren...

Frost & Sullivan Applauds SHL Telemedicine for Excellence in Product Innovation

...ystem. (Logo: http://www.newscom.com/cgi-bin/prnh/20081117/FSLOGO ) "The CardioSen'C(TM) is a revolutionary product that transmits digital encoded ECG data through the cellular network (GPRS) and allows for comparable ECG accuracy due to the elimination of background noise present when using acou...

Finesse Demonstrates TruFluor(TM) pH, a Single-Use Optical pH Sensor and Transmitter

...H Sensor, by enabling automatic entry of calibration and traceability data using RFID, diagnostics, and verification. The calibration and lot data are encoded on a gamma radiation resistant tagging of disposable sheath. The RFID data is automatically read by the transmitter, thereby eliminating the need to c...

Finesse Announces TruTorr(TM) Single-Use Pressure Sensor

...ni or PLSS). The single-use sensor automatically compensates for temperature, and is self-calibrated. Specifically, the calibration and lot data are encoded on a gamma-radiation-resistant memory chip that is integrated inside the sensor and follows it through production and sterilization. This chip is aut...

Stanford writes in world's smallest letters

...rs in the words are assembled from subatomic sized bits as small as 0.3 nanometers, or roughly one third of a billionth of a meter. The researchers encoded the letters "S" and "U" (as in Stanford University) within the interference patterns formed by quantum electron waves on the surface of a sliver of co...
Encoded in Biological Products

pHyPer-dMito from Evrogen JSC

Description:... HyPer is the first fully genetically encoded fluorescent sensor capable for high specific detection of intracellular hydrogen peroxide (H2O2), one of the main ROS generated by cells. Developed on...
Company:Evrogen JSC

Rabbit Anti-Kv4.2 Polyclonal Antibody, Unconjugated from GeneTex

Description:...ants of the resting membrane potential and of membrane excitability, conditioning the frequency, and shape of action potential. Potassium channels are encoded by numerous genes whose products can be classified into distinct subfamilies of which the most distinctively characterized is that of the Kv1 shaker c...
Company:GeneTex

Mouse Anti-PRKAR2 Monoclonal Antibody, Unconjugated, Clone RS17 from GeneTex

Description:...free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits of AMPK have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. It may interact with various A-...
Company:GeneTex

Mouse Anti-MAP1 Light Chain Monoclonal Antibody, Unconjugated, Clone E12 from GeneTex

Description:... microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Immunogen: Bovine brain MAPs preparation. Specifici...
Company:GeneTex

Human Topoisomerase I Wild Type from Calbiochem

Description:...M DTT, 200 µM EDTA, 20% glycerol, pH 7.9. AVOID FREEZE/THAW CYCLES. Human DNA topoisomerase I (Topo I) is a monomeric protein of 765 amino acids encoded by a single-copy gene. It catalyzes the relaxation of both positive and negative supercoiled DNAs without the requirement of energy. In addition to DN...
Company:Calbiochem

Mouse Anti-RFC1 Monoclonal Antibody, Unconjugated, 1320 from GeneTex

Description:...quence-unspecific manner to DNA, is localized exclusively in the nucleus, and represents the 140-kD subunit of mouse replication factor C. The protein encoded by this cDNA showed 83% identity to the human protein....
Company:GeneTex
Encoded in Biological Definition

Alternative splicing

... eukaryotes it was a very important step towards higher efficiency, because information can be stored much more economically. Several proteins can be encoded in a DNA sequence whose length would only be enough for two proteins in the prokaryote way of coding. Others have noted that it is unnecessary to ch...

Amino acid

...blocks. They form short polymer chains called peptides or polypeptides which in turn form structures called proteins . Twenty amino acids are encoded by the standard genetic code and are called proteinogenic or standard amino acids . Rarer, more complicated ones are produced by the body and are...

Archaea

...icrobials, Dr Sarah Maloney Citat: "...Ground breaking research on extremophiles continues to this day, with the recently discovered 22nd genetically encoded amino acid – pyrrolysine – from the archaeon, Methanosarcina barkeri , (Hao et al., 2002; Srinivasan et al., 2002)...." BBC News ...

DNA

...s organized as two complementary strands, head-to-toe, with bonds between them that can be "unzipped" like a zipper, separating the strands; DNA is encoded with four interchangeable "building blocks", called " bases ", which can be abbreviated A , T , C , and G ; each base "pairs up" with only one oth...

Endosymbiotic theory

...yanobacteria. DNA sequence analysis and phylogeny suggests that nuclear DNA contains genes that probably came from the chloroplast. Some genes encoded in the nucleus are transported to the organelle, and both mitochondria and chloroplasts have unusually small genomes compared to other organisms. This...

Epigenetics

...smitted from one generation (of cells or organisms) to the next - that is (harking back to the Greek prefix), 'in addition to' the genetic information encoded in the DNA. In recent years, there has been rapid progress in understanding epigenetic mechanisms, which include differences in DNA methylation ,...
Encoded in Biological Dictionary

Viral oncogene

... is transformed as soon as ... v-rel reticuloendotheliosis viral oncogene homolog (avian), also known as REL, is a human gene. The protein encoded by the human REL gene is a member of the NF-κB family of transcription factors. The REL gene is amplified or mutated in several human B-ce...

Tubulin

...as long thought to be specific to eukaryote. Eukaryote ... Drosophila has four ß- tubulin genes: each encodes a distinct isoform. ... Maternally encoded ß1 tubulin is incorporated into zygotic mitotic spindles. ... The four ß- tubulin genes of Drosophila each encode a distinct isoform. ... The ß3...

Transferrin receptor

... transferrin receptor maintains cellular iron homeostasis. Transferrin is a blood plasma protein for iron ion delivery that, in humans, is encoded by the TF gene. Transferrin is a glycoprotein that binds iron very tightly but reversibly. Although iron bound to transferrin is less... Tra...

Splicing factor

... ASF serine-rich 1 or SFRS1, is a protein which in humans is encoded by the SFRS1 gene. ASF SF2 and is found on chromosome 17. The resulting splicing factor is a protein of approximately 33 kDa. ASF SF2 also media...

Ribosomes

...rms, the smaller, 70S ... It was expected that organellar ribosomes would be 70S particles (reminiscent of ... Explanation of how the information encoded in mRNA is translated into a polypeptide. ... Ribosomes that synthesize 13 of the proteins destined for the inner ... Ribosome , cell struct...

Pseudorevertant

...oned pseudorevertant sequence (ANISI 1) had a ... Both of the pseudorevertant proteins self-aggregate, and neither of the ... The protein encoded by the z11G3 pseudorevertant of z1 has a deletion of the ... ...
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