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Encephalopathy in Medical News

Center for the Study of Traumatic Encephalopathy announces new findings

(TAMPA, FLA) Leading medical experts at the Center for the Study of Traumatic Encephalopathy (CSTE) at Boston University School of Medicine (BUSM) reported today that nine-year NFL veteran, former Tampa Bay Buccaneer Tom McHale was suffering from chronic traumatic encephalopathy (CTE), a degenera...

Hyperion Therapeutics Announces Enrollment of First Patient in Phase 2 Clinical Trial in Patients With Hepatic Encephalopathy

SOUTH SAN FRANCISCO, Calif., Feb. 25 /PRNewswire/ -- Hyperion Therapeutics, Inc. today announced that the first patient has been enrolled in a Phase 2 clinical trial of AMMONUL(R) (sodium phenylacetate and sodium benzoate) Injection 10%/10% in patients with Grade III or IV hepatic encephalopat...

Whole-body hypothermia reduces risk of death in Encephalopathy in infants

Among infants, hypoxic–ischemic encephalopathy due to acute perinatal asphyxia remains an important cause of neurodevelopmental deficits in childhood//. Infants with moderate encephalopathy have a 10% risk of death, and those who survive have a 30% risk of disabilities. 60% of infants with seve...

Hyperion Therapeutics Raises $60 Million Series C

...mmonemia) resulting in brain damage, coma, and/or death. About Hepatic encephalopathy Hepatic encephalopathy (HE) is a serious but potentially reversible neurological disorder that can...

Farmed fish may pose risk for mad cow disease

... be contracted by eating parts of an animal infected with bovine spongiform encephalopathy (BSE or mad cow disease). An outbreak in England attributed to infected bee...n the United Kingdom attributed to eating infected beef. Bovine spongiform encephalopathy has been identified in nine Canadian and three U.S. cattle. ...

Hyperion Therapeutics Announces Results of Phase I Study in Patients With Liver Cirrhosis

...ny preparing to initiate phase II trial in hepatic encephalopathy - SOUTH SAN FRANCISCO, Calif., June 2 /PRNews...hemistry, and coagulation variables. "Hepatic encephalopathy (HE) is a significant clinical problem," said Bren...program for the use of HPN-100 in treating hepatic encephalopathy later this year. About Hepatic...

Resuscitated Newborns at Risk for Lower IQs

...ollowing birth called encephalopathy. The signs of encephalopathy can be seizures, abnormalities of muscle tone, abn...who require resuscitation at birth but are free of encephalopathy will have normal growth and development. "It wa...ren who had to be resuscitated and had symptoms of encephalopathy had more than a sixfold risk of having a low IQ. ...

Liver Cirrhosis May Also Harm Brain, Heart

...issues and a condition known as hepatic (liver) encephalopathy, which occurs when an increasing amount of unfiltered toxins reaches the brain. Hepatic encephalopathy can affect both physical and mental performance. All three conditions are linked to increased systemic inflammation, say a team from the Universit...

Give the foie gras a miss

...l mechanism akin to the replication of similar protein fragments in the brain diseases Creutzfeldt-Jakob Disease (CJD), scrapie, and Bovine Spongiform encephalopathy (BSE), also known as mad cow disease, might occur when amyloid fibrils enter brain tissue or the pancreas. He points out that high levels of these mat...

Hunter-Killed Elk Test Negative for CWD and Other Diseases

...tor for and collect samples from deer and elk that appear sick or behave abnormally. First identified in 1967, CWD is a transmissible spongiform encephalopathy (TSE) that affects cervids, including all species of deer, elk and moose. It is a progressive and always fatal disease, which scientists theorize is c...
Encephalopathy in Medical Technology

Schering-Plough Highlights Hepatitis C Clinical Data Presentations at the European Association for the Study of the Liver (EASL) Annual Meeting

...ia, injection site necrosis, vasculitis and phototoxicity. Additional serious adverse events included hallucinations. bipolar disorder, mania, encephalopathy (usually elderly treated with higher doses of PEGINTRON), hypotension, tachycardia, retinopathy including macular edema, retinal hemorrhage, cotton wo...

Final Results of Boceprevir Phase II HCV SPRINT-1 Study Showed Significantly Higher SVR Rates Compared to Standard of Care in Treatment-Naive Genotype 1 Hepatitis C Patients

...ia, injection site necrosis, vasculitis and phototoxicity. Additional serious adverse events included hallucinations. bipolar disorder, mania, encephalopathy (usually elderly treated with higher doses of PEGINTRON), hypotension, tachycardia, retinopathy including macular edema, retinal hemorrhage, cotton wo...

FDA Approves an Expanded Indication for Peginterferon-Based Combination Therapy for Patients With Chronic Hepatitis C

...ia, injection site necrosis, vasculitis and phototoxicity. Additional serious adverse events included hallucinations. bipolar disorder, mania, encephalopathy (usually elderly treated with higher doses of PEGINTRON), hypotension, tachycardia, retinopathy including macular edema, retinal hemorrhage, cotton wo...

Schering-Plough Provides Update on Boceprevir Clinical Development and Introduces Potent Next-Generation Oral HCV Protease Inhibitor for Treating Patients With Chronic Hepatitis C

...eatment with PEGINTRON and/or INTRON A be discontinued, and the patient be carefully followed with psychiatric intervention, as appropriate. Cases of encephalopathy have been observed in some patients, usually elderly, treated with higher doses of PEGINTRON and/or INTRON A. Ischemic and hemorrhagic cerebrovascula...

Boceprevir Phase II Study Showed High Rate of Sustained Response With 28- and 48-Week Regimens in Genotype 1 Treatment-Naive Hepatitis C Patients

...reatment with PEGINTRON and/or INTRON A be discontinued, and the patient be carefully followed with psychiatric intervention, as appropriate. Cases of encephalopathy have been observed in some patients, usually elderly, treated with higher doses of PEGINTRON and/or INTRON A. Ischemic and hemorrhagic cerebrovascular...

Variant of Mad Cow Disease May Be Transmitted by Blood Transfusions, According to Animal Study

... a study in sheep prepublished online in Blood, the official journal of the American Society of Hematology, the risk of transmitting bovine spongiform encephalopathy (BSE, commonly known as "mad cow disease") by blood transfusion is surprisingly high. BSE is one of a group of rare neurodegenerative disorders call...

Top-Line Results of Boceprevir Phase II Study Showed High Rate of Sustained Response (SVR) in Genotype 1 Treatment-Naive Hepatitis C Patients

...reatment with PEGINTRON and/or INTRON A be discontinued, and the patient be carefully followed with psychiatric intervention, as appropriate. Cases of encephalopathy have been observed in some patients, usually elderly, treated with higher doses of PEGINTRON and/or INTRON A. Ischemic and hemorrhagic cerebrovascular...

Schering-Plough To Initiate Phase III Studies With HCV Protease Inhibitor Boceprevir in Previously Untreated Hepatitis C Patients and Those Who Failed Prior Treatment

...reatment with PEGINTRON and/or INTRON A be discontinued, and the patient be carefully followed with psychiatric intervention, as appropriate. Cases of encephalopathy have been observed in some patients, usually elderly, treated with higher doses of PEGINTRON and/or INTRON A. Ischemic and hemorrhagic cerebrovascular...

Schering-Plough Highlights PEGINTRON(TM) and Boceprevir Hepatitis C Data Presentations at Digestive Disease Week (DDW) Annual Meeting

...reatment with PEGINTRON and/or INTRON A be discontinued, and the patient be carefully followed with psychiatric intervention, as appropriate. Cases of encephalopathy have been observed in some patients, usually elderly, treated with higher doses of PEGINTRON and/or INTRON A. Ischemic and hemorrhagic cerebrovascular...

Arbios Receives Approval From the FDA to Initiate Pivotal Trial for SEPET(TM) Liver Assist Device

...e of the trial. This segment is targeted to achieve the co-primary endpoints, which are 1) the percentage of patients achieving improvement in hepatic encephalopathy ("HE") grade by a minimum of two grades by the end of Day 7 in the SEPET treatment group versus the standard medical care group, using a 1:1 randomiza...
Encephalopathy in Medical Products

Bioglue

Description:...rgical adhesive composed of purified bovine serum albumin (BSA) and glutaraldehyde. The BSA is obtained from cattle exclusively from bovine spongiform encephalopathy (BSE) free countries and undergoes processing that reduces or inactivates viruses. The solutions are dispensed by a controlled delivery system, compos...
Company:Cryolife, Inc.
Encephalopathy in Medical Definition

Pathology

...l pathology ( E40-68 ) Malnutrition Kwashiorkor - Marasmus Other underconsumption B vitamins : B1: Beriberi / Wernicke's encephalopathy , B2: Ariboflavinosis , B3: Pellagra , B7: Biotin deficiency , B9: Folate deficiency other vitamins : A: Vitamin A deficiency / Bitot's spo...

Proteopathy

...ers (multiple) Proteins with tandem glutamine expansions Familial British dementia ABri Familial Danish dementia ADan Familial encephalopathy with neuroserpin inclusion bodies (FENIB) Neuroserpin Hereditary cerebral hemorrhage with amyloidosis (Icelandic) (HCHWA-I) Cystatin C ...
Encephalopathy in Medical Dictionary

Hepatic encephalopathy

Hepatic encephalopathy is a potentially-reversible neuropsychiatric abnormality in the setting of liver failure, whether chronic, or acutely. It can be diagnosed only after exclusion of other neurological, psychiatric,... Hepatic encephalopathy is caused by disorders that affect the liv...

Bovine Spongiform Encephalopathy

Bovine spongiform encephalopathy (BSE), commonly known as mad-cow disease (MCD), is a fatal, neurodegenerative disease in cattle, that causes a spongy degeneration in the brain and spinal cord. BSE has a long incubation... Bovine Spongiform Encephalopathy (BSE) is a transmissible, n...

Scrapie

...pongiform encephalopathies (TSEs), which are related to bovine spongiform encephalopathy and... Information on this fatal degenerative disease of sheep and go...neration of the Scrapie is a small ruminant, transmissible spongiform encephalopathy (TSE). Although in the past scrapie has not been considered a zoonosis, t...

Neonatal

...iversity of ... Aims to improve the quality and safety of medical care for newborn infants and their families. ... The Registry for Neonatal encephalopathy ... ...

Mad Cow Disease

... Bovine spongiform encephalopathy (BSE), commonly known as mad - cow disease (MC...r prions, mad cow disease (bovine spongiform encephalopathy or BSE), scrapie, Creutzfeldt-Jakob Disease (CJD... ... Mad cow disease , or bovine spongiform encephalopathy (BSE) ... Britain Bans Sale of Older Cattle to...

Krabbe disease

...tic disorder of the nervous system. From the University of Maryland Medical Center. globoid cell leukodystrophy ( ) n. An inherited metabolic encephalopathy of infancy with rapidly ... Infants with Krabbe disease are normal at birth. ... Krabbe disease Definition Krabbe disease is an inheri...

Hepatic

...hich leave the liver and empty ... Hepatic encephalopathy is a potentially-reversible neuropsychiatric abnor...nd complications. ... The exact cause of hepatic encephalopathy is unknown. ... Hepatic encephalopathy is brain and nervous system damage that occurs as ...
Encephalopathy in Biological News

Ocera Therapeutics licenses novel treatment for acute hepatic encephalopathy from UCLB

LONDON and SAN DIEGO, April 2, 2009 University College London Business PLC (UCLB) and Ocera Therapeutics Inc., a privately held biopharmaceutical company, announced the signing of an exclusive worldwide licensing agreement for UCL-L1V and all assets and technologies related to the compound for th...

Experimental treatment halts hypoxic-ischemic brain injury in newborns

...may be a promising therapeutic target in infants suffering hypoxic-ischemic encephalopathy (HIE). Identification of a treatment target is a vital step to finding better ways to treat newborns with HIE. "Not only is hypoxic-ischemic encephalopathy an important cause of perinatal mortality and permanent neurological morbid...

Antibody key to treating variant CJD, scientists find

...umans. It is thought that those who have developed vCJD became infected through the consumption of cattle products contaminated with Bovine Spongiform encephalopathy (BSE) a brain disorder in cows, commonly known as Mad Cow Disease. Prion diseases can develop when a naturally occurring brain prion protein calle...

Genetic mutation causes familial susceptibility for degenerative brain disease

...e in and out of the cell's genetic command center the nucleus puts some families at higher risk for the degenerative brain disease acute necrotizing encephalopathy (ANE). This is the conclusion of a global study to be published Jan. 9 by the American Journal of Human Genetics , and currently posted online, th...

K-State professor's USDA research shows mad cow disease also caused by genetic mutation

... Richt said, it was thought that the cattle prion disease bovine spongiform encephalopathy -- also called BSE or mad cow disease -- was a foodborne disease. But his t...t a 10-year-old cow from Alabama with an atypical form of bovine spongiform encephalopathy had the same type of prion protein gene mutation as found in human patients...

Scripps scientists develop new tests that identify lethal prion strains quickly and accurately

...stands for proteinaceous infectious particles) are unique infectious pathogens associated with some 15 different diseases, including Bovine Spongiform encephalopathy (mad cow) and its rare human form, variant Creutzfeldt-Jacob disease. Infectious prions, which are thought to consist mainly of an abnormally structur...

New treatment for severe malaria

..., researchers at Karolinska Institutet in Sweden have developed a powerful new weapon against the disease. Severe anaemia, respiratory problems and encephalopathy are common and life-threatening consequences of serious malaria infection. The diseases are caused when the malaria bacteria P.falciparium infects the...

Prion find points way to test for human 'mad cow' disease

...ymptoms. The scientists say that they detected prions--the infectious proteins responsible for such brain-destroying disorders as bovine spongiform encephalopathy (BSE) in cattle and vCJD in humans--in the blood of the hamsters in as few as 20 days after the animals had been infected. That discovery occurred abo...

Brittle prions are more infectious

...ety for their roles in such fatal brain-destroying human diseases as Creutzfeldt-Jakob disease and kuru, and in the animal diseases, bovine spongiform encephalopathy ("mad cow" disease) and scrapie. Yeast and mammalian prions are proteins that transmit their unique characteristics via interactions in which an ab...

Successful cell engineering may lead to mad cow prevention, say researchers

...s in a cloned goat fetus, perhaps paving the way for breeding disease resistance in other animals, even those genes that might cause bovine spongiform encephalopathy (BSE), commonly known as Mad Cow Disease. Researchers Mark Westhusin and Charles Long in Texas A&M's College of Veterinary Medicine & Biomed...
Encephalopathy in Biological Technology

Ocera Therapeutics Presents Data on AST-120 in Patients With Hepatic Encephalopathy at the European Association for the Study of Liver Disease Annual Meeting

The Company also Initiates the Phase 2b ASTUTE Clinical Trial for Mild Hepatic Encephalopathy SAN DIEGO, April 28 /PRNewswire/ -- Ocera Therapeutics, Inc., a privately held biopharmaceutical company, announced that data from its phase 2 study of AST-120 for the treatment of patients with low-...

Sanofi Pasteur Responds to Nation's Need for Hib Vaccine With Increased Supply

...eipt of a prior vaccine containing tetanus toxoid; or if adverse events have occurred in temporal relation to receipt of pertussis-containing vaccine. encephalopathy within 7 days of administration of a previous dose of a pertussis-containing vaccine or a progressive neurologic disorder is a contraindication. Vacci...

Astellas Receives FDA Approval for Use of Prograf(R) (Tacrolimus) in Conjunction With Mycophenolate Mofetil (MMF) in Kidney Transplant Recipients

...a concentrations of tacrolimus. In post marketing experience, patients treated with tacrolimus have been reported to develop posterior reversible encephalopathy syndrome (PRES). If PRES is suspected or diagnosed, immediate reduction of immunosuppression is advised. Activation of latent viral infections, inclu...

Arbios Announces It Has Suspended Operations

...ohn Vierling, M.D., FACP, Chairman of Arbios and Professor of Medicine and Surgery and Chief of Hepatology at the Baylor College of Medicine. "Hepatic encephalopathy represents one of the most frequent complications of cirrhosis necessitating hospitalization, and SEPET's rapid time to a sustained two-stage improvem...

CDC Immunization Advisory Committee Recommends Two New Pediatric Vaccines from GlaxoSmithKline

...wsiness, fever, and loss of appetite. Previous hypersensitivity to any component of KINRIX, including neomycin and polymyxin B, is a contraindication. encephalopathy within 7 days of administration of a previous pertussis-containing vaccine or a progressive neurologic disorder is a contraindication. The decision to...

ProMetic announces Octapharma publication of PRDT'S prion removal resin in Octaplas(R) manufacturing process at 30th International Congress of the International Society for Blood Transfusion meeting in Macao SAR, China

...will have some of the world leading authorities in Transmissible Spongiform encephalopathy ("TSE") disease research presenting data on the utility of Pathogen Removal...1996 following a massive exposure of the UK population to Bovine Spongiform encephalopathy ("BSE"; 'Mad Cow Disease') contaminated meat and other bovine products duri...

IDEXX Laboratories Announces First Quarter Results

...rowth. The favorable impact of higher sales volume was partly offset by lower average unit sales prices for our post-mortem test for bovine spongiform encephalopathy ("BSE") due to greater price competition. Compared to the same period of 2007, changes in foreign currency exchange rates contributed 12% to PAS reven...

ProMetic to obtain controlling stake in Pathogen Removal and Diagnostic Technologies Inc.

...regori L, Lambert BC, Gurgel P et al. Reduction of transmissible spongiform encephalopathy infectivity from human red blood cells with prion protein affinity ligand. ...fects humans, scrapie, which infects sheep and goats, and Bovine Spongiform encephalopathy ("BSE"), a newly emergent disease that affects both cattle and humans. Dr. ...

Prometic to present at the American Chemical Society

...neurodegenerative diseases that include Creutzfeldt-Jakob disease, which infects humans, scrapie, which infects sheep and goats, and Bovine Spongiform encephalopathy ("BSE"), a newly emergent disease that affects both cattle and humans. Dr. Rohwer's studies on the kinetics of inactivation of the TSE agents have pro...

U.S. FDA Licenses DAPTACEL(R) Vaccine for the Fifth Consecutive Dose in the Pediatric DTaP Immunization Series

...CEL vaccine should not be given to children who, after a previous dose of the vaccine, have had a serious allergic reaction (anaphylactic reaction) or encephalopathy not attributable to another cause. For more information about DAPTACEL vaccine, refer to the Patient Information on DAPTACEL.com and talk to your ch...
Encephalopathy in Biological Definition

Brain

...re caused by germs. Viral or bacterial infection of the meninges, the membrane that covers the brain, can lead to meningitis . Bovine spongiform encephalopathy is a deadly disease among cattle and is linked to prions . Some brain disorders are congenital . Tay-Sachs disease , Fragile X syndrome , D...

Prion

...erally classified under transmissible spongiform encephalopathy diseases (TSEs) , including scrapie (a disease ... Chronic Wasting Disease , and bovine spongiform encephalopathy (mad cow disease). These diseases affect the st... Scrapie prion OvPrP Sc Transmissible mink encephalopathy (TME) Mink TME prion MkPrP Sc Chronic...

Urea cycle

...ors of metabolism ), and in liver failure . The result in liver failure is accumulation of nitrogenous waste, mainly ammonia, which leads to hepatic encephalopathy . Reactions of cycle: NH 3 (ammonia) + CO 2 + 2 ATP → carbamoyl phosphate + 2 ADP + P i ( catalyzed by carbamoyl phosphate...
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(Date:4/17/2014)... most popular vaccine brands for children may not be ... some cost factors when choosing vaccines, driving the market ... to a new study by University of Illinois researchers. ... driven by numerous factors," says Sheldon H. Jacobson, a ... science and of mathematics at the U. of I. ...
(Date:4/17/2014)... issue of Experimental Biology and Medicine ... Gaskins and Paul Kenis in the Institute of ... University of Illinois Urbana-Champaign describe their recent work ... a variety of cell functions including energy metabolism, ... roles in regulating normal cellular behavior, redox status ...
(Date:4/17/2014)... Colo. (April 17, 2014) Two recent papers ... researcher and colleagues may help scientists develop treatments ... Yellow fever, Japanese encephalitis and other disease-causing flaviviruses. ... biochemistry and molecular genetics at the School of ... Howard Hughes Medical Institute, and colleagues recently published ...
(Date:4/17/2014)... Jon McCullers, MD, was recently invited to submit ... Nature Reviews Microbiology , one of the world,s ... infectious disease specialist, and chair of the Department ... Science Center, analyzed the epidemiology and microbiology of ... as well as more recent 2009 novel H1N1 ...
(Date:4/17/2014)... New Rochelle, NY, April 17, 2014U.S. military personnel ... "blast plus impact" concussive traumatic brain injury (TBI) ... were evacuated for other medical reasons. Differences in ... and depression 6-12 months after injury are reported ... , a peer-reviewed journal from Mary Ann Liebert, ...
Breaking Medicine News(10 mins):Health News:Study recalculates costs of combination vaccines 2Health News:Live cell imaging reveals distinct alterations of subcellular glutathione potentials 2Health News:CU researchers discover target for treating dengue fever 2Health News:Long-term effects of battle-related 'blast plus impact' concussive TBI in US military 2
(Date:4/20/2014)... gene expression analysis growing in importance for both ... Mellon University and the University of Maryland have ... up estimates of gene activity from RNA sequencing ... after the famously speedy fish, estimates of gene ... completed in a few minutes, with accuracy that ...
(Date:4/20/2014)... newborn baby a gift of germsgerms that help ... used to fend off infection, may paradoxically interrupt ... babies more susceptible to dangerous pathogens. , ... The Children,s Hospital of Philadelphia (CHOP) sheds light ... microbes play a crucial role in fostering the ...
(Date:4/20/2014)... crop residue to make ethanol and other biofuels reduces ... gasoline, according to a study published today in the ... by a University of Nebraska-Lincoln team of researchers cast ... meet federal mandates to ramp up ethanol production and ... stalks, leaves and cobs in cornfields after harvest -- ...
Breaking Biology News(10 mins):Computational method dramatically speeds up estimates of gene expression 2Study of gut microbes, antibiotics: Clues to improving immunity in premature infants 2Study casts doubt on climate benefit of biofuels from corn residue 2Study casts doubt on climate benefit of biofuels from corn residue 3
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