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Embo in Medical News

Olivier Voinnet awarded 2009 EMBO Gold Medal

Heidelberg, Germany, 22 April 2009 - Olivier Voinnet from the CNRS Institute of Plant Molecular Biology in Strasbourg, France, is awarded the 2009 EMBO Gold Medal. The researcher receives this medal for his pioneering work on the mechanisms and roles of gene silencing via RNA in plants. With th...

Stopgap DNA repair needs a second step

...letters after the damaged site; only one repair enzyme is capable of performing this vital second step. These findings were published recently in the embo Journal . Understanding how this major form of DNA repair works can have significant clinical implications. Since defects in this process increase ...

Bioengineered proteins: Trial confirms new way to tackle cancer

...ing and growing has created a potentially powerful therapy for people with many different types of cancer. In a study published in the first issue of embo Molecular Medicine , Canadian researchers modified the tumour inhibiting protein, von Hippel-Lindau (VHL), and demonstrated that it could suppress tum...

Seven life scientists get research boost to set up in Europe

... embo Installation Grants are awarded annually and aim t...science in selected member states of the EMBC, the embo intergovernmental funding body. The EMBC Member St...nity. Grantees are integrated into the prestigious embo Young Investigator network, providing networking o...

Sour comes after a lemon has gone

...f acid stimulus. They call this new type of response as "off-response" of sour taste receptor. They reports their finding in an international journal, embo reports, on June 6, 2008. They investigated the PKD1L3-PKD2L1 channel activity stimulated by acid stimulus with calcium imaging method and electrop...

South African scientists access European research via EMBC agreement

...ing scientists from South Africa to participate in embo programmes and activities. The agreement also provides for some embo activities to occur in South Africa. embo recognises and fosters talented scientists, empowe...

The good and bad side of anti-cancer compounds

... will eventually come in, he says. HDAC inhibition isnt without side effects, however. And another recent paper from Hieberts lab, published in the embo Journal in March, provides some insight into how HDAC inhibition might cause liver damage. In that study, Hieberts group turned off HDAC3 in the l...

The structure of resistance

...s Descartes has solved the structure of two proteins that allow bacteria to gain resistance to multiple types of antibiotics, according to a report in embo reports this month. This work provides new clues as to how bacteria adapt to resist antibiotics and how to design new drugs that counteract this defen...

Lost in the middle: author order matters, new paper says

..., and the order in which the authors names are listed makes a big difference. The new findings appear in the Nov. 1 issue of the scientific journal embo Reports. OMRFs Jonathan Wren, Ph.D., is the first author on the paper, which is entitled The write position. In scientific circles, the long-accept...

How Candida albicans transforms from its normally benign form into life-threatening form

...r other diseases that damage the immunity of the individual. In two separate papers published last month in Developmental Cell and in August in the embo journal, the team of scientists led by Wang Yue, principal investigator at IMCB, have managed to reveal previously unknown mechanisms which are respon...

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Embo in Medical Technology

Resveratrol Studies Suggest Broad Implications for SIRT1 Activation in Neurodegenerative Diseases of Aging Such as Alzheimer's Disease

...etylation of PGC1a. Resveratrol also promoted neuronal survival in cell based models of Alzheimer's Disease and ALS. The three senior authors of the embo article include Sirtris co-founder and co-chair of the Scientific Advisory Board (SAB), David A. Sinclair, Ph.D., Department of Pathology and Paul F. ...
Embo in Biological News

Call for abstracts and registration for the EMBO Meeting 2009

HEIDELBERG, GERMANY, 25 MARCH 2009 More than 120 researchers will speak at The EMBO Meeting 2009 the first annual life sciences conference to be organized by the European Molecular Biology Organization (EMBO) and held in Amsterdam from 29 August to 1 September 2009. The EMBO Meeting 2009 adv...

12 outstanding young scientists named as EMBO Young Investigators

Heidelberg, 5 November 2008 - Today, the European Molecular Biology Organization (EMBO) announced the selection of 12 of Europe's most talented young researchers as 2008 beneficiaries of the EMBO Young Investigator Programme. Now in its ninth year, the programme annually identifies the brightes...

Prominent German biologist wins EMBO Communication Award

Today, the European Molecular Biology Organization (EMBO) announced that the German evolutionary biologist Axel Meyer from the University of Konstanz, Germany, will receive the 2008 EMBO Award for Communication in the Life Sciences. EMBO awards the prize annually to a practicing scientist in Europ...

James Briscoe awarded 2008 EMBO Gold Medal

The European Molecular Biology Organization (EMBO) announced that James Briscoe of the Medical Research Council's National Institute for Medical Research will receive the prestigious EMBO Gold Medal for 2008. Briscoe receives the award in recognition of his discovery that cells integrate time o...

18 young scientists join EMBO Young Investigator network

The European Molecular Biology Organization (EMBO) announced today the selection of 18 of Europes most talented young researchers as the 2007 beneficiaries of its prestigious Young Investigator Programme. Each year since 2000, the programme identifies and supports outstanding young life scienti...

EMBO pioneers pension plan for internationally mobile postdoctoral researchers

...the introduction of a new private pension plan for embo Fellows. The plan offers a benefit package that op...t-doctoral researchers who are beneficiaries of an embo Long-Term Fellowship may begin enrolling in the pe...y move from country to country," said Jan Taplick, embo Deputy Director and manager of...

Protecting cells from their neighbors

... Made in the fruit fly Drosophila melanogaster , this finding could be universal. This research is published today in the advanced online edition of embo Reports . In the first hours of embryonic life, the egg cells show intense gene transcription activity to initiate development, with the exception ...

Parasites ready to jump

...n develop. We now want to find out whether mammalian cells possess this newly discovered defence mechanism and to elucidate precisely how it works." ( embo Journal online, 30 July 2009.) Transposons constitute a significant fraction of the genomes of most higher organisms. Indeed, it is estimated that...

Double success for Instituto Gulbenkian de Ciencia scientists working on chromosome segregation

...a paper in Nature Cell Biology and a prestigious embo installation grant, of 50,000 euro per year, for a...e centromere assembly and function, was awarded an embo installation grant and entrance into the prestigio... propose in this project. Moreover, entry into the embo Young Investigator Programme allows me to fully in...

Investigating the development of mechanosensitivity

...evelop their sensitivity to touch and pain during different developmental phases but always coincidentally with the growth of the neuronal pathways. ( embo Journal , 2009, doi:10.1038/emboj.2009.73).* The sensory neurons, which are sensitive to touch and pain, are located in the dorsal root ganglia bet...
Embo in Biological Technology

Enzyme promotes fat formation

... The enzyme TPPII may contribute to obesity by stimulating the formation of fat cells, suggests a study in embo reports this week. The enzyme, TPPII, has previously been linked to making people feel hungry, but Jonathan Graff and colleagues now show that it may ...

USB OptiKinase Eliminates Base Bias in Labeling of Oligonucleotide 5'-Ends

...A., PELLETIER, J., WILSON, G., AND STODDARD, B. L. (2002) Structure 10 , 1249- 1260. 2. WANG, L. K., LIMA, C. D., AND SHUMAN, S. (2002) embo J. 21 , 3873-3880. 3. RICHARDSON, C. C. (1981) The Enzymes , 3 rd Edition, Ed. P. D. Boyer, (Academic Press, New York) 14 , 299-314. ...

Transformation of Nematodes With the Helios Gene Gun

... D., J. Mol. Biol., 164 , 355375 (1983). 7. Fire, A., embo J., 5 , 26732680 (1986). 8. Franz, M. and Andrews, P., Z. Parasi... 9. Jefferson, R. A., Kavanagh, T. A. and Bevan, M. W., embo J., 6 , 39013907 (1987). 10. Kramer, J. M., French, R...

Sub-Micron Gold Particles Are Superior to Larger Particles for Efficient Biolistic Transformation of Organelles and Some Cells

...or correlating the genetic and molecular maps of the ARG7 locus, embo J., 8 , 2803-2809 (1989). 7. Goff, S. A., Klein, T. M., Roth, B.... genes following transfer of B regulatory genes into maize tissues, embo J., 9 , 2517-2522. (1990). 8. Klein, T. M., Goff, S. ...

Optimization of Biolistic Transformation Using the Helium-Driven PDS-1000/He System

.... A., Kavanagh, T. A. and Bevan, M. W., GUS fusions: β-glucuronidase as a sensitive and versatile gene fusion marker in higher plants, embo J., 6 , 3901-3907 (1987). Johnston, S. A., Anziano, P. Q., Shark, K., Sanford, J. C. and Butow, R. A., Mitochondrial ...

Biolistic Gene Transfer to Generate Transgenic Schistosomes, Rev A

... Gillingham AK and Munro S, The PACT domain, a conserved centrosomal targeting motif in the coiled-coil proteins AKAP450 and pericentrin, embo Rep 1, 524529 (2000) Grevelding CG et al., Female-specific gene expression in Schistosoma mansoni is regulated by pair...

Using the VersaFluor Fluorometer to Quantitate GUS Expression in Plant Tissues Bombarded With the Biolistic PDS-1000/He System

...er is reliable, simple, and accurate. References 1. Jefferson, R. A., Kavanagh, T. A. and Bevan, M. W., embo 6 , 3901-3907 (1987). 2. Kay, R., Chan, A., Daly, M. and McPherson, J., Science, 236 , 1299-1302 (1987). 3...

New Fusion Trans-Activator Plasmids for Studying Signal Transduction Pathways

...719-1723. Price, M.A., et al. (1995) embo J. 14: 2589-2601. Marais, R., Wynne,... Smeal, T., Hibi, M., and Karin, M. (1994) embo J. 13: 6006-6010. Lu, Q., and ... Livingstone, C., Patel, G., and Jones, N. (1995) embo J. 14: 1785-1797. Maekawa, T.,...

New Reporter Plasmids for Studying Interferon-Stimulated Signal Transduction Pathways

...anscription factors can be monitored with these two new PathDetect cis-reporter plasmids. REFERENCES Decker, T., et al. (1991) embo J. 10: 927-932. Wilks, A.F. and Harpur, A.G. (1994) BioEssays 16: 313-320. Ihle, J.N. (1996) Cell 84: 331-334. ...

Improved Vectors for PathDetect Trans-Reporting Systems

...al. (1994) Science 266: 1719-1723. Price, M.A., et al. (1995) embo J. 14: 2589-2601. Marais, R., Wynne, J., and Treisman, R. (19... 73: 381-393. Smeal, T., Hibi, M., and Karin, M. (1994) embo J. 13: 6006-6010. Xing, J., et al. (1996) Science 273: ...
Embo in Biological Dictionary

Polycistronic

... expression system enables the coexpression of up to 4 ... We have used this polycistronic expression system to produce milligrams of ... The embo Journal is a science journal containing review articles and research ... Furthermore, most polycistronic transcripts comprise genes contributing ......

Minicircles

...hen undergo replication, ultimately forming singly and ... The partially or fully replicated minicircles migrate to two antipodal sites ... The embo Journal is a science journal containing review articles and research papers in the broad areas of ... Minicircles , however, are unconventional, ... ...

Branch migration

...h migration to the distal end results in irreversible dissociation of the ... Figure 2 Population-averaged branch migration assay. ... The embo Journal is a science journal containing review articles and research papers in the broad areas of molecular, structural and cellular biology. ANALY...
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