New Study Data: JANUVIA™ (sitagliptin) Significantly Reduced Blood Sugar Levels and Was Not Associated with Hypoglycemia in Elderly Patients with Type 2 Diabetes

...icity assay, a Chinese hamster ovary (CHO) chromosome aberration assay, an in vitro cytogenetics assay in CHO, an in vitro rat hepatocyte DNA alkaline elution assay, and an in vivo micronucleus assay. rat fertility studies with oral gavage doses of 125, 250, and 1000mg/kg, males were treated for 4 wee...

QLT announces third quarter results for 2008

...nue to be significant to the Company and provide additional funding for our internal development programs, including our proprietary punctal plug drug elution technology trials. As we announced separately this morning, the data from our Phase 2 CORE trial showed a meaningful reduction in intra-ocular pressur...

QLT Inc. announces initial steps in strategic restructuring

... with drug technology and initiation of a Phase I/II clinical trial in glaucoma patients in H1, with results on plug retention and drug elution expected by year end 2008. 3) Photodynamic therapy with Lemuteporfin (QLT00748): Human proof-of- concept studies for the treatment of moder...

GlaxoSmithKline Obtains Exclusive U.S. OTC Marketing Rights to MEVACOR(R) (lovastatin) from Merck & Co., Inc.

...rium with or without rat or mouse liver metabolic activation. In addition, no evidence of damage to genetic material was noted in an in vitro alkaline elution assay using rat or mouse hepatocytes, a V-79 mammalian cell forward mutation study, an in vitro chromosome aberration study in CHO cells, or an in viv...

Prototype Detector detects Anthrax Quickly

... ester emitted in the analyzed gases at particular times - a process called elution - with already categorized elution peaks indicative of anthrax or other diseases. ...

Elution in Medical Technology

Micell Technologies Presents Data on Novel Drug-Eluting Stents

...rovements to conventional solvent based systems by maintaining control of drug morphology, targeting drug placement within the coating and customizing elution rates of single or multiple drugs. In addition, the SCF method avoids solvents and high temperatures so it can be used with new therapeutic classes, s...

Late Breaking Data Released at ADA Showed that the Investigational Use of Januvia and Metformin as Initial Combination Therapy Provided Significant Glucose Lowering Efficacy over 54 Weeks in Patients with Type 2 Diabetes

...ity assay, a Chinese hamster ovary (CHO) chromosome aberration assay, an in vitro cytogenetics assay in CHO, an in vitro rat hepatocyte DNA alkaline elution assay, and an in vivo micronucleus assay. In rat fertility studies with oral gavage doses of 125, 250, and 1000 mg/kg, males were treated for ...

An Investigational Study Released at ADA Showed that Initial Combination Therapy with Januvia (sitagliptin) and Metformin Led to Improvement in Markers of Beta Cell Function in Patients with Type 2 Diabetes

...ity assay, a Chinese hamster ovary (CHO) chromosome aberration assay, an in vitro cytogenetics assay in CHO, an in vitro rat hepatocyte DNA alkaline elution assay, and an in vivo micronucleus assay. In rat fertility studies with oral gavage doses of 125, 250, and 1000 mg/kg, males were treated for ...

Elution in Medical Products

High Pure Viral RNA Kit

Description:... is intended for general laboratory use and is designed to purify viral RNA from serum or plasma. Viral RNA is used for RT-PCR analysis directly after elution in nuclease-free water....
Company:Roche Diagnostics

Vacuum Manifold

Description:... in sample handling. The manifold is designed for consistent processing and elution of up to 12 samples simultaneously. Loading, washing, and elution steps can be performed rapidly, and all fractions can be collected in indiv...
Company:Novagen

Impulse

Description:...he pacemaker system by providing energy efficient pacing. The high impedance of the lead as a result of the small electrode surface, combined with the elution of steroid, saves energy and extends pacemaker longevity....
Company:Vitatron B.V.

CapSureZ Novus

Description:... The CapSure Z Novus is an endocardial, tined, high-efficiency lead. High efficiency combined with steroid elution allows safe, low output programming....
Company:Medtronic Inc.

Impulse II

Description:...he pacemaker system by providing energy efficient pacing. The high impedance of the lead as a result of the small electrode surface, combined with the elution of steroid, saves energy and extends pacemaker longevity....
Company:Vitatron B.V.

Tendril SDX Model 1488T

Features:... Steroid elution TiN-coated electrodes Silicone insulation Fast-Pass coating T models use a proprietary one-handed fixation tool. ...
Company:St. Jude Medical, Inc.

Tendril SDX Model 1688TC

Features:... Steroid elution TiN-coated electrodes Silicone insulation Fast-Pass coating TC models use a standard clip-on tool ...
Company:St. Jude Medical, Inc.

Tendril SDX Model 1688T

Features:... Steroid elution TiN-coated electrodes Silicone insulation Fast-Pass coating T models use a proprietary one-handed fixation tool ...
Company:St. Jude Medical, Inc.

MagNA Pure Compact System

Features:...igh quality nucleic acids from diverse sample types with proven reagent chemistry. Incorporate a variety of protocols using different specimen and elution volumes for a broad range of sample materials. Save time through easy setup with pre-filled reagents and disposables. Eliminate contamination ...
Company:Roche Diagnostics

TVL™ ADX Leads

Features:... True bipolar Single shock Single-coil cardioversion Low defibrillation Steroid elution Active fixation helix...
Company:St. Jude Medical, Inc.

Elution in Biological Technology

Higher gDNA Concentrations with the Perfect gDNA Blood Mini Kit by Varying the Final Elution Volume

Higher gDNA Concentrations with the Perfect gDNA Blood Mini Kit by Varying the Final Elution Volume Laura Pollock and Jennifer Halcomez Eppendorf 5 Prime, Boulder, Colorado Introduction ...

Higher gDNA Concentrations with the Perfect gDNA Blood Mini Kit by Varying the Final Elution Volume

Higher gDNA Concentrations with the Perfect gDNA Blood Mini Kit by Varying the Final Elution Volume Laura Pollock and Jennifer Halcomez Eppendorf 5 Prime, Boulder, Colorado Introduction ...

febit First to Offer Newly Published Mouse Genome on a Chip for DNA/RNA Detection and Enrichment

...rofiling applications as well as targeted Next-Generation Sequencing. HybSelect, sequence-specific DNA enrichment is enabled through hybridization and elution of high-value target regions by utilizing febit's flexible Geniom Biochips. The enriched DNA is ideally suited for cost-effective targeted sequencing ...

ElutraSep Inc. Announces the Launch of the Cryptonite™ HV Filter Module for Cryptosporidium and Giardia Testing

...ntages including a recovery procedure with a total elution volume of less than 50 milliliters, no specialized elution equipment or post filtration required and a start ...aboratories will no longer have to conduct tedious elution protocols or have to deal with hundreds of millili...

OrbusNeich's Genous(TM) Bio-engineered R stent(TM) Demonstrates Impressive Results in Higher Risk Patients

...d results from pre-clinical models demonstrating the effectiveness in combining OrbusNeich's pro-healing cell capture with their fully absorbable drug elution technologies to address the shortcomings with current drug eluting stents (DES), namely the safety concerns associated with the delay and often lack o...

Micell Technologies' Rapid Absorption Polymer DES System to be Presented at CRT 2009

...ventional cardiology systems. By applying its unique surface and polymer modification technologies, Micell can precisely and consistently control drug elution and the duration of polymer exposure creating the potential for a therapeutic solution for coronary artery disease without the long-term safety concer...

Micell Forges Strategic Agreement to Develop Advanced Drug-Eluting Stents and Balloons

...a drug-polymer formulation that can precisely and consistently control drug elution and the duration of polymer exposure. As a result, Micell's coating has the...dification technologies, Micell can precisely and consistently control drug elution and the duration of polymer exposure creating the potential for a therapeut...

QLT reports initial proof of concept data for punctal plug delivery technology

... Small study supports the potential for QLT's drug elution technology to reduce and sustain in... program is to demonstrate that the Company's drug elution technology leads to a statistically significant re...nted today are an early indication that QLT's drug elution technology has the potential to provide a meaningf...

Boston Scientific Receives Canadian Approval for TAXUS(R) Liberte(R) Stent System

...interventional cardiologists and patients in Canada who suffer from coronary artery disease." "This stent is designed specifically for improved drug elution and deliverability," said David McFaul, Boston Scientific Senior Vice President, International. "Coupled with our proven paclitaxel-eluting technology...

Mobile Phase Optimization for the Analysis of an Antibody-Based Fusion Protein and Aggregates using a TSKgel Super SW3000 Size-Exclusion Column

... Introduction: During method development, many variables are examined to ensure method robustness. Factors such as elution profile, peak shape, and recovery are required to be consistent by GMP/GLP protocols. During a recent method re-qualification at...

Elution in Biological Products

RiboCap™ from RNAture, Inc.

Description:...well GenePlate®. RiboCap™ plates are available in larger package sizes and contain the appropriate buffers for cell lysis, hybridization or elution of mRNA....
Company:RNAture, Inc.

T7Select Biopanning Kit from Novagen

Description:... Kit Components 25 g Blocking Reagent 2 x 50 ml 10X TBST Wash Buffer 10 ml T7 elution Buffer 0.2 ml BL21 glycerol stock 0.2 ml BLT5403 glycerol stock 0.2 ml BLT5615 glycerol stock 1010 pfu T7Select Positive Control L...
Company:Novagen

One•STrEP™ Protein Interaction Kit from Novagen

Description:...ctor StrepTag II Antibody HRP Conjugate PP2Ac Goat Polyclonal Antibody 1X StrepTactin Lysis Buffer 1X StrepTactin Wash Buffer 1X StrepTactin elution Buffer with Biotin ...
Company:Novagen

GST Expression and Purification Kit from BD Biosciences Pharmingen

Description:...-XylE Baculovirus Control Vector Thrombin Powder Thrombin Dilution Buffer Protease Inhibitor Cocktail Insect Cell Lysis Buffer Glutathione Powder GST elution Buffer PBS Wash Buffer Transfection Buffer...
Company:BD Biosciences Pharmingen

ImmunoPure IgM Purification Kit from Pierce Biotechnology, Inc.

Description:...emonstrates the high purity of Immobilized MBP purified IgM from mouse ascites. Immobilized MBP Column 5 ml IgM Binding Buffer 800 ml IgM elution Buffer 500 ml MBP Column Preparation Buffer 50 ml Column Extender ...
Company:Pierce Biotechnology, Inc.

Autotrace SPE Workstation from Caliper Life Sciences

Description:...workstation dedicated specifically for automating Solid Phase Extraction (SPE). The AutoTrace automates the cartridge conditioning, sample loading and elution steps for large volumes aqueous solution extractions (up to 2000ml's). ...
Company:Caliper Life Sciences

Ultra Agarose Spin Kit from ABgene

Description:...utes Low melting point agarose not required Can be used for TAE and TBE gels No specialised equipment required DNA is eluted into sterile water or elution buffer (supplied) No precipitation required Size Range DNA 100bp50kb Applications Purification of DNA from all types of agarose gels...
Company:ABgene

DNA Spin Gel Extraction/PCR Purification Kit from Yorkshire Bioscience Ltd

Description:...e for PCR product with equal volume of binding buffer. Up to 25 g of DNA can be purified with a single prep using YORBIO Gel/PCR DNA Purification Kit. elution volume 25-50 ul...
Company:Yorkshire Bioscience Ltd

Rabbit Anti-PLAU N-term RB4087 Polyclonal Antibody, Unconjugated from Abgent

Description:... sodium azide. This antibody is purified through a protein G column and eluted out with both high and low pH buffers and neutralized immediately after elution then followed by dialysis against PBS....
Company:Abgent

Catch & Release v2.0 High Throughput (HT) Immunoprecipitation Assay Kit- 96 well from Upstate

Description:...ashing the protein A/G agarose without disrupting the agarose bed. The binding of the antibody/antigen complex in Catch and Release is reversible, and elution of the immune complex can occur with native or denaturing buffers. The system has been tested successfully with rabbit, mouse, sheep and goat antibodi...
Company:Upstate

Elution in Biological Definition

Affinity chromatography

...terest is the unbound mixture, and the washing and elution steps can be omitted or used simply for analytical... purposes of solid medium entrapment [ [1] ]. For elution purposes a nickel chelating agent is used. GST has...ercially available as glutathione sepharose ). For elution purposes glutathione is used. Another use for th...