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Eliciting in Medical News

Yerkes researchers propose ambitious new strategies for AIDS vaccine research

...inated individuals from HIV transmission or disease progression. This has been demonstrated in two large-scale clinical trials aimed, respectively, at eliciting HIV specific-antibodies to neutralize the virus and stimulating the immune system's "killer T-cells" to target the virus. "To put it another way, a...

Tips from the journals of the American Society for Microbiology

... New DNA Vaccine Inhibits Deadly Skin Cancer in Mice A new DNA vaccine inhibited malignant melanoma, a deadly form of skin cancer, in mice by eliciting antibodies that target a gastrin-releasing peptide which is known to play a key role in cancer development. The researchers from China and the U.S. r...

Aderans Research BIO International Press Release

...ir supply for any one person. Through leading edge cell engineering, Aderans Research is pioneering efforts to multiply existing hair cells capable of eliciting hair growth, providing patients with a comprehensive solution to hair loss regardless of the quantity of their existing hair. About the BIO Inter...

If You Could Travel to Mars, Would You Go?

... digitally counted as they enter through a YES or NO gate. At the exhibit's exit, the question is repeated: "Would You Still Go to Mars?" - this time eliciting from visitors a more reflective answer. In challenging visitors to bring their own perspectives to the human toll of long space voyages as well as eng...

Team Regrows Neurons Controlling Movement in Rats

... connections that arise from some types of cells affected by a spinal cord injury," Tuszynski said. "However, until now, there has not been success in eliciting the regeneration of injured connections from corticospinal motor axons, cells which are essential to restoring voluntary movement in humans." While...

AST President-Elect Joren Madsen Attends Regional White House Forum on Health Care Reform

...Madsen noted, "Health care reform is one of our country's most pressing issues. I commend President Obama for bringing this issue to the forefront and eliciting feedback from a wide range of participants." About AST The American Society of Transplantation is an international organization of transpl...

Scripps Research Institute and IAVI launch world's first dedicated HIV neutralizing antibody center

...clinical testing were devised almost exclusively to elicit cell-mediated immune (CMI) responses. Most existing vaccines against other diseases work by eliciting neutralizing antibodies. The NAC is part of a global AIDS vaccine discovery program that extends to Africa, Asia and Europe. Current members of the...

Reeve Foundation Recruits Distinguished Stem-Cell Neurobiologist - The Salk Institute's Samuel L. Pfaff, Ph.D. - to its International Research Consortium

...across eight international laboratories that focuses on optimizing the intrinsic capacity of the adult nervous system to repair and remodel itself and eliciting robust regenerative responses after injury. "Dr. Pfaff's expertise in the embryonic development of the spinal cord will add significant value to our...

Study sees need for standardized evaluation of antibody response to HIV-1

...neutralizing antibodies are likely to play a key role in any successful global vaccine for HIV. This study looked specifically at the role of clade in eliciting protective responses. Working with USMHRP colleague Francine McCuthan, Ph.D., researchers had access to a wide range of pure clade reagents, which the...

Whom do we fear or trust?

...hose models were established, the scientists could exaggerate faces along these dimensions, show them to other test subjects to confirm that they were eliciting the predicted emotional response, and find out what facial features are critical for different social judgments. "If you can think of an emotion be...
Eliciting in Medical Technology

Data Presented at AUA Demonstrate PROVENGE Significantly Prolongs Survival for Men With Advanced Prostate Cancer in Pivotal Phase 3 IMPACT Study

...munotherapies (ACI). PROVENGE and other ACIs are uniquely designed to use live human cells to engage the patient's own immune system with the goal of eliciting a specific long-lasting response against cancer. Conference Call Scheduled for Today at 5:30 pm ET Dendreon will host a conference call tod...

Nobilon Advances First Vaccine Into Human Trials - Intranasal Influenza Vaccine Begins Phase I Clinical Development

...ve Attenuated Influenza Vaccine (LAIV) is expected to be more effective in inducing local and cellular immunity and as such may be more efficacious in eliciting protection. About SCH 900795 Nobilon acquired in 2004 the majority of rights to develop, commercialize and manufacture the LAIV technology fr...

12-Month ATLANTA Trial Data Show Sustained Benefit of Catania(TM) Stent in Treatment of De Novo Coronary Lesions

...ncluding other polymers, metals, and ceramics. Medical devices coated with Polyzene(R)-F do not cause a negative reaction in the body when introduced, eliciting a normalized and positive bodily response. Polyzene(R)-F can be customized for the desired application and applied in a variety of ways including as a...

Dendreon Announces Interim Data From Phase 3 PROVENGE IMPACT Trial

...class of active cellular immunotherapies that are uniquely designed to use live human cells to engage the patient's own immune system with the goal of eliciting a specific long-lasting response against cancer. Active cellular immunotherapy holds promise because it may provide patients with a meaningful clinica...

Successful Results for Mymetics Corporation's Mucosal HIV/AIDS Vaccine Viral Challenge Significantly Exceeds Expectations

... antigen engineering, minimal human protein homologies and virosome technology licensed from Pevion Biotech Ltd. Mymetics' vaccine approach focuses on eliciting immune protection capable of interfering with late events of pathogen transmission, a generally accepted approach coupled, uniquely and most important...

ActivBiotics Proposes Development Strategy for Its Novel Rifamycin Antibiotics

...cins rifampin and rifabutin have been used because of their potency against these pathogens. However, these rifamycins share the negative attribute of eliciting drug-drug interactions; that is, they interfere with the actions of many other medications that the patient may require. The NCEs are breakthrough dru...

GeoVax Vaccine Only 5th AIDS Vaccine Moving to Phase 2 Human Trials

...e has been selected to move forward into Phase 2 trials. Our vaccine continues to demonstrate the promise of not only being safe but also effective at eliciting potentially protective immune responses," stated Dr Harriet Robinson, Senior Vice President, Research & Development at GeoVax. "GeoVax is extremely ...

Pre-clinical Data on Recent Advances with HIV VLP Vaccine Presented at AIDS Vaccine 07 Conference

...de. The study also demonstrated that HIV-1 VLPs formulated without an adjuvant were as potent as an adjuvanted protein subunit vaccine with respect to eliciting neutralizing antibody responses to both tier 1 and tier 2 viruses. Dr. Richard Compans, chairman of the department of microbiology and immunology, Em...

Cell Genesys Reports GVAX Immunotherapy for Prostate Cancer Induces a Broad, Patient-Specific Antibody Response

...t for the concept that a whole-cell immunotherapy, such as GVAX immunotherapy for prostate cancer, is an ideal multi-antigen source that is capable of eliciting an immune response to a broad array of tumor-associated antigens," stated Peter K. Working, Ph.D., senior vice president of Research and Development a...

CytoGenix to Present at 2007 International DNA Vaccines Conference in Spain

...asites in many species from fish to primates. Our animal tests demonstrate that DNA vaccines made with synDNA(TM) technology are not only effective in eliciting robust immune responses, but also provide protection against dangerous pathogens. Presentation of our data at the DNA vaccine conference is a great op...
Eliciting in Biological News

Nano vaccine for hepatitis B shows promise for third world

...oxicity studies in rodents and dogs showed the vaccine was safe and well-tolerated. The vaccine was as effective as current hepatitis B vaccines in eliciting systemic protective antibodies in the blood of animals. The nanoemulsion acted as an effective adjuvant, without the need for a traditional adjuvant o...

Killer whales, blind bats, discriminating dolphins, mating birds

...ubs in future studies, to better establish the meaning of the communications. Paper 4pABd1, "Vocalizations of the Spotted Hyena (Crocuta crocuta): eliciting Acoustic Variation in Groans" will be presented at 5:20 p.m. on Thursday, July 3 in room 343. 4) CHINESE FROGS GO ULTRASONIC Among vertebrates, ...

LIAI researchers discover new cellular mechanism that will significantly advance vaccine development

...response from the B cells, we can cross check that against the viral pieces eliciting a good response from the CD4 T cells. The point at which these virus pieces cross in other words where the same piece is eliciting a response from both the B cells and CD4 T cells then we know we have foun...

Sirtris unveils promising, novel SIRT1 activators for treating diseases of aging

.... Milne, Ph.D., lead author of the Nature study and Senior Director of Biology at Sirtris. Westphal added, Now we have an even more potent way of eliciting the beneficial effects observed in earlier research with resveratrol. The NCEs characterized in this study are significantly more potent than and str...

ATR checkpoint-activating DNA structure

...se have been uncovered, this type of structural information is quite novel and valuable. The elucidation of the first defined DNA structure capable of eliciting the ATR checkpoint will aid researchers to further identify additional checkpoint proteins, as well as understand how checkpoint signals are generated...

Novel antigen-cloning technique may boost efforts to develop a melanoma vaccine

...r lab, RPL8, is an ideal vaccine candidate because it has the potential for eliciting both helper T cells and CTL responses, Herlyn says. RPL8 is a protein invol...dy also showed that RPL8 might contain multiple regions that are capable of eliciting an immune response, suggesting that RPL8 may be an ideal vaccine target for...

Scientists unveil piece of HIV protein that may be key to AIDS vaccine development

...n and this neutralizing antibody," says NIAID Director Anthony S. Fauci, M.D. "This finding could help in the development of an HIV vaccine capable of eliciting a robust antibody response." For years, AIDS vaccine developers have been stymied by the seemingly unlimited ways HIV eludes natural and vaccine...

Progress made in HIV vaccine development

...r accompanying editorial. "The DNA studies are a landmark for DNA-based vaccines in that they are the first to demonstrate a DNA vaccine successfully eliciting immune responses in essentially all vaccinated volunteers," they said. "The Ad5 recombinant HIV vaccine had both a higher percentage of responders an...

Radiation-killed bacteria vaccine induces broad immune response in mice

...ive response from immune system cells called T cells. Previously, only vaccines made from live, weakened Listeria bacteria were believed capable of eliciting a T-cell response. "This advance is potentially of great importance in meeting the challenge of creating vaccines that are safe, effective and s...

Do plants have the potential to vaccinate against HIV?

...ues in Dr Julian Ma's laboratory are working with the p24 core protein of the Human Immunodeficiency Virus (HIV). This protein plays a central role in eliciting the immune response to HIV infection, and is therefore likely to be an integral part of any multicomponent vaccine for HIV. Plants have already be...
Eliciting in Biological Technology

Dendreon Announces Data on PROVENGE Potency and Long-Term Immune Responses in Androgen-Dependent Prostate Cancer

...unotherapies (ACIs). PROVENGE and other ACIs are uniquely designed to use live human cells to engage the patient's own immune system with the goal of eliciting a specific long-lasting response against cancer. In controlled clinical trials, the most common adverse events were chills, fever, headache, fatigue, ...

PROVENGE Significantly Prolongs Survival in Men With Advanced Prostate Cancer in Pivotal Phase 3 IMPACT Study

...unotherapies (ACIs). PROVENGE and other ACIs are uniquely designed to use live human cells to engage the patient's own immune system with the goal of eliciting a specific long-lasting response against cancer. In controlled clinical trials, the most common adverse events were chills, fever, headache, fatigue,...

GeoVax Labs, Inc. Reports Fourth Quarter and Year-End 2008 Financial Results

... were similar for the 1/10th and full dose. O Two DNA primes were more effective than one DNA prime or no DNA primes at eliciting T cell responses. O The second MVA vaccination positively increased CD8 T cell and antibody responses. Dr. Harriet...

CeloNova BioSciences Commercializes CATANIA(TM) Coronary Stent With NanoThin Polyzene(R)-F in Europe and Middle East

...ncluding other polymers, metals, and ceramics. Medical devices coated with Polyzene(R)-F do not cause a negative reaction in the body when introduced, eliciting a normalized and positive bodily response. Polyzene(R)-F can be customized for the desired application and applied in a variety of ways including as a...

GeoVax Labs, Inc. Announces Third Quarter 2008 Financial Results and Provides Operational Update

... were similar for the 1/10th and full dose. o Two DNA primes were more effective than one DNA prime or no DNA primes at eliciting T cell responses. o The 2nd MVA vaccination positively increased CD8 T cell and antibody responses. Dr. Harriet Robinson, the ...

GeoVax Presents Data at AIDS Vaccine 2008 Conference

...s response rates for T cells were similar for the 1/10th and full dose. -- Two DNA primes were more effective than one DNA prime or no DNA primes at eliciting T cell responses. -- The 2nd MVA vaccination positively increased CD8 T cell and antibody responses. "As the entire world tries to find a solution...

Nventa announces publication of HspE7 data

...m dosing regimen for inducing effective antitumor immunity. These published study results demonstrated that a single injection of HspE7 is capable of eliciting long-lasting memory CD8+ T cells and conferring protection against tumor challenges in mice lacking CD4+ functions. CD8+ T cells are a type of white b...

Intra-Cellular Therapies Provides Overview of its Proprietary Portfolio of Compounds for the Treatment of Female Sexual Dysfunction (FSD)

...nly classified as "female sexual dysfunction." ITI's molecules have demonstrated promising activity in animal models of sexual behavior, specifically eliciting enhanced female sexual interest and activity. The Company's lead compounds show behavioral effects equivalent to those observed after treatment with p...

For Now, Michigan Can Celebrate $150 Million Entrepreneurial VC Fund

...yers). If the guarantee is as reported, economists would call it a subsidy. Subsidies are notorious for leading to overly risky investment and for eliciting more quantity than objective conditions warrant. This may be exactly the reason for the MVIC, but if so, its a risk for Michigan taxpayers and workers...

With patents and research tools, when is private really public?

...n contrast, the facts of a later case concerned a dentist inventor who installed an inventive orthodontic appliance in several of his patients without eliciting or receiving an express promise of confidentiality. The Federal Circuit recognized the confidential nature of the dentist-patient relationship and the...
Eliciting in Biological Definition

Apoptosis

... recognize PS and carry out their disposal job in an orderly manner without eliciting an inflammatory response [5] , [6] . In studies on mouse embryos lacki...esponse not only contributes to tumor suppression, but is also important in eliciting an apoptotic response to viral infection and consequent damage to the cell'...
Eliciting in Biological Dictionary

Epitope

...nself proteins, sequences derived from the host that can... epitope ( ) n. A localized region on the surface of an antigen that is capable of eliciting an immune response and of combining with a specific Linear epitope Recognition of epitopes in a linear fashion. ... If you have 5 epitops how...

Conformational epitope

... Clonal deletion. Antigen. Immune complex. Immunogenetics ... epitope ( ) n. A localized region on the surface of an antigen that is capable of eliciting an immune response ... Epitope (Linear, Conformational ) Antibodies ... a web interface to the conformational epitope pre- diction algorit...
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